Simvastatin induces estrogen receptor-alpha expression in bone, restores bone loss, and decreases ERα expression and uterine wet weight in ovariectomized rats

Journal of Bone and Mineral Metabolism

Volumn 29, Issue 4, 2011, Pages 396-403

  Li, Xu ^a   Song, Quan Sheng ^a   Wang, Jing Ying ^a   Leng, Hui Jie ^a   Chen, Zhong Qiang ^a   Liu, Zhong Jun ^a   Dang, Geng Ting ^a   Song, Chun Li ^a  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

Bone; Estrogen receptor alpha (ER ); Osteoporosis; Simvastatin; Uterus

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; SIMVASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE MASS; BONE STRENGTH; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ESTROGEN DEFICIENCY; ESTROGEN METABOLISM; FEMALE; LUMBAR VERTEBRA; MONOTHERAPY; NONHUMAN; OSTEOLYSIS; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UTERUS WEIGHT;

ABSORPTIOMETRY, PHOTON; ANIMALS; BIOMECHANICS; BLOTTING, WESTERN; BODY WEIGHT; BONE AND BONES; BONE DENSITY; BONE RESORPTION; ESTROGEN RECEPTOR ALPHA; FEMALE; IMMUNOHISTOCHEMISTRY; LUMBAR VERTEBRAE; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; SIMVASTATIN; UTERUS;

EID: 80052450615     PISSN: 09148779     EISSN: 14355604     Source Type: Journal    
DOI: 10.1007/s00774-010-0231-y     Document Type: Article

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