Transcriptional activation of TMSG-1 by complex of KLF6 and Sp1

Chinese Journal of Pathology

Volumn 40, Issue 8, 2011, Pages 542-548

  Gong, Miao Zi ^a   You, Jiang Feng ^a   Pei, Fei ^a   Cui, Xiang Lin ^a   Gang, L I ^a   Zheng, Jie ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Cell line; Genes; Genetic; Neoplasm metastasis; Transcription; Tumor; Tumor suppressor

Indexed keywords

CERS2 PROTEIN, HUMAN; KLF6 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; MEMBRANE PROTEIN; MESSENGER RNA; ONCOPROTEIN; SPHINGOSINE ACYLTRANSFERASE; TRANSCRIPTION FACTOR SP1; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BINDING SITE; CANCER INVASION; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; GENETICS; HUMAN; IMMUNOPRECIPITATION; LUNG TUMOR; MALE; METABOLISM; MUTATION; PATHOLOGY; PROSTATE TUMOR; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

BINDING SITES; CELL LINE, TUMOR; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; IMMUNOPRECIPITATION; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LUNG NEOPLASMS; MALE; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEOPLASM INVASIVENESS; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; SPHINGOSINE N-ACYLTRANSFERASE; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 80052447064     PISSN: 05295807     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0529-5807.2011.08.009     Document Type: Article

References (11)

1. Ma C., Liu Y., Zheng J., et al. Identification of tumor metastasisrelated gene TMSG-1 by mRNA differential display. Sci China C Life Sci, 2002, 45(5): 553-560.
2. Xu X.Y., Pei F., You J.F. TMSG-1 and its roles in tumor biology. Chin J Cancer, 2010, 29(7): 697-702.
3. Pewzner-Jung Y., Ben-Dor S., Futerman A.H. When do Lasses (longevity assurance genes) become CerS (ceramide synthases) ? Insights into the regulation of ceramide synthesis. J Biol Chem, 2006, 281 (35): 25001-25005. (Pubitemid 44401887)
4. Pewzner-Jung Y., Park H., Laviad E.L., et al. A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways. J Biol Chem, 2010, 285(14): 10902-10910.
5. Li H., Liu H., Wang Z., et al. The role of transcription factors Sp1 and YY1 in proximal promoter region in initiation of transcription of the mu opioid receptor gene in human lymphocytes. J Cell Biochem, 2008, 104(1): 237-250.
6. Albini A., Iwamoto Y., Kleinman H.K., et al. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res, 1987, 47(12): 3239-3245. (Pubitemid 17082655)
7. Vostrov A.A., Taheny M.J., Izkhakov N., et al. A nuclear factorbinding domain in the 5'-untranslated region of the amyloid precursor protein promoter: Implications for the regulation of gene expression. BMC Res Notes, 2010, 3: 4.
8. Botella L.M., Sanz-Rodriguez F., Komi Y., et al. TGF-beta regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3-Spl-KLF6 interaction. Biochem J, 2009, 419(2): 485495.
9. DiFeo A., Martignetti J.A., Narla G. The role of KLF6 and its splice variants in cancer therapy. Drug Resist Updat, 2009, 12 (1-2): 1-7.
10. DiFeo A., Narla G., Camacho-Vanegas O., et al. E-cadherin is a novel transcriptional target of the KLF6 tumor suppressor. Oncogene, 2006, 25(44): 6026-6031. (Pubitemid 44477296)
11. Das A., Fernandez-Zapico M.E., Cao S., et al. Disruption of an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration. J Biol Chem, 2006, 281 (51): 39105-39113. (Pubitemid 46041869)