Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication

Structure

Volumn 19, Issue 9, 2011, Pages 1317-1327

  Osborne, Brent W ^a   Wu, Jian ^b   McFarland, Caitlin J ^a   Nickl, Christian K ^a   Sankaran, Banumathi ^c   Casteel, Darren E ^d   Woods Jr , Virgil L ^d   Kornev, Alexandr P ^b   Taylor, Susan S ^b   Dostmann, Wolfgang R ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE IALPHA; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CATALYTIC DOMAIN; CATTLE; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENZYME ASSAYS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 80052446199     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2011.06.012     Document Type: Article

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