메뉴 건너뛰기




Volumn 16, Issue 3, 2011, Pages 477-492

The use of a human papillomavirus 18 promoter for tissue-specific expression in cervical carcinoma cells

Author keywords

Cervical cancer; E2 binding site; Gene therapy; HPV18; Long control region

Indexed keywords

DNA FRAGMENT; E2 PROTEIN; LUCIFERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 80052441278     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-011-0018-8     Document Type: Article
Times cited : (7)

References (57)
  • 1
    • 67651147063 scopus 로고    scopus 로고
    • Implications of HPV infection in uterine cervical cancer
    • Jo, H. and Kim, J. W. Implications of HPV infection in uterine cervical cancer. Cancer Ther. 3 (2005) 419-434.
    • (2005) Cancer Ther. , vol.3 , pp. 419-434
    • Jo, H.1    Kim, J.W.2
  • 5
    • 0033560677 scopus 로고    scopus 로고
    • Improved treatment for cervical cancer-concurrent chemotherapy and radiotherapy
    • Thomas, G. M. Improved treatment for cervical cancer-concurrent chemotherapy and radiotherapy. N. Engl. J. Med. 340 (1999) 1198-1200.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1198-1200
    • Thomas, G.M.1
  • 6
    • 0035216188 scopus 로고    scopus 로고
    • The role of chemotherapy in invasive cancer of the cervix uteri: current standards and future prospects
    • Rein, D. T. and Kurbacher, C. M. The role of chemotherapy in invasive cancer of the cervix uteri: current standards and future prospects. Anticancer Drugs12 (2001) 787-795.
    • (2001) Anticancer Drugs , vol.12 , pp. 787-795
    • Rein, D.T.1    Kurbacher, C.M.2
  • 8
    • 65749089629 scopus 로고    scopus 로고
    • Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis
    • Dorer, D. E. and Nettelbeck, D. M. Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis. Adv. Drug. Deliv. Rev. 61 (2009) 554-571.
    • (2009) Adv. Drug. Deliv. Rev. , vol.61 , pp. 554-571
    • Dorer, D.E.1    Nettelbeck, D.M.2
  • 9
    • 34447526800 scopus 로고    scopus 로고
    • Impact of the human papilloma vaccine on cervical cancer
    • Chan, J. K. and Berek, J. S. Impact of the human papilloma vaccine on cervical cancer. J. Clin. Oncol. 25 (2007) 2975-2982.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 2975-2982
    • Chan, J.K.1    Berek, J.S.2
  • 10
    • 33646675570 scopus 로고    scopus 로고
    • Molecular biology of human papillomavirus infection and cervical cancer
    • Doorbar, J. Molecular biology of human papillomavirus infection and cervical cancer. Clin. Sci. (Lond)110 (2006) 525-541.
    • (2006) Clin. Sci. (Lond) , vol.110 , pp. 525-541
    • Doorbar, J.1
  • 11
    • 77956233744 scopus 로고    scopus 로고
    • HPV is detectable in virtually all abnormal cervical cytology samples after reinvestigation of HPV negatives with multiple alternative PCR tests
    • Evans, M. F., Adamson, C. S., Schned, L. M., St John, T. L., Leiman, G., Ashikaga, T. and Cooper, K. HPV is detectable in virtually all abnormal cervical cytology samples after reinvestigation of HPV negatives with multiple alternative PCR tests. Diagn. Mol. Pathol. 19 (2010) 144-150.
    • (2010) Diagn. Mol. Pathol. , vol.19 , pp. 144-150
    • Evans, M.F.1    Adamson, C.S.2    Schned, L.M.3    St John, T.L.4    Leiman, G.5    Ashikaga, T.6    Cooper, K.7
  • 12
    • 0034612296 scopus 로고    scopus 로고
    • Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein
    • Butz, K., Denk, C., Ullmann, A., Scheffner, M. and Hoppe-Seyler, F. Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 6693-6697.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 6693-6697
    • Butz, K.1    Denk, C.2    Ullmann, A.3    Scheffner, M.4    Hoppe-Seyler, F.5
  • 13
    • 0035208333 scopus 로고    scopus 로고
    • Identification of a promoter in position 56 within the long control region of human papillomavirus type 18
    • Steger, G., Rehtanz, M. and Schnabel, C. Identification of a promoter in position 56 within the long control region of human papillomavirus type 18. Arch. Virol. 146 (2001) 2069-2084.
    • (2001) Arch. Virol. , vol.146 , pp. 2069-2084
    • Steger, G.1    Rehtanz, M.2    Schnabel, C.3
  • 14
    • 0023199906 scopus 로고
    • Characterization of a transcriptional promoter of human papillomavirus 18 and modulation of its expression by simian virus 40 and adenovirus early antigens
    • Thierry, F., Heard, J. M., Dartmann, K. and Yaniv, M. Characterization of a transcriptional promoter of human papillomavirus 18 and modulation of its expression by simian virus 40 and adenovirus early antigens. J. Virol. 61 (1987) 134-142.
    • (1987) J. Virol. , vol.61 , pp. 134-142
    • Thierry, F.1    Heard, J.M.2    Dartmann, K.3    Yaniv, M.4
  • 15
    • 0021821058 scopus 로고
    • Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines
    • Yee, C., Krishnan-Hewlett, I., Baker, C. C., Schlegel, R. and Howley, P. M. Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines. Am. J. Pathol. 119 (1985) 361-366.
    • (1985) Am. J. Pathol. , vol.119 , pp. 361-366
    • Yee, C.1    Krishnan-Hewlett, I.2    Baker, C.C.3    Schlegel, R.4    Howley, P.M.5
  • 16
    • 0025879362 scopus 로고
    • The viral transcriptional regulatory region upstream of the E6 and E7 genes is a major determinant of the differential immortalization activities of human papillomavirus types 16 and 18
    • Romanczuk, H., Villa, L. L., Schlegel, R. and Howley, P. M. The viral transcriptional regulatory region upstream of the E6 and E7 genes is a major determinant of the differential immortalization activities of human papillomavirus types 16 and 18. J. Virol. 65 (1991) 2739-2744.
    • (1991) J. Virol. , vol.65 , pp. 2739-2744
    • Romanczuk, H.1    Villa, L.L.2    Schlegel, R.3    Howley, P.M.4
  • 17
    • 78650748371 scopus 로고    scopus 로고
    • Persistence of human papillomavirus infection: keys to malignant progression
    • Bodily, J. and Laimins, L. A. Persistence of human papillomavirus infection: keys to malignant progression. Trends Microbiol. 19 (2011) 33-39.
    • (2011) Trends Microbiol. , vol.19 , pp. 33-39
    • Bodily, J.1    Laimins, L.A.2
  • 18
    • 77952236280 scopus 로고    scopus 로고
    • Activities of E7 promoters in the human papillomavirus type 16 genome during cell differentiation
    • Hansen, C. N., Nielsen, L. and Norrild, B. Activities of E7 promoters in the human papillomavirus type 16 genome during cell differentiation. Virus Res. 150 (2010) 34-42.
    • (2010) Virus Res. , vol.150 , pp. 34-42
    • Hansen, C.N.1    Nielsen, L.2    Norrild, B.3
  • 19
    • 77954955259 scopus 로고    scopus 로고
    • Human papillomavirus oncoproteins: pathways to transformation
    • Moody, C. A. and Laimins, L. A. Human papillomavirus oncoproteins: pathways to transformation. Nat. Rev. Cancer10 (2010) 550-560.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 550-560
    • Moody, C.A.1    Laimins, L.A.2
  • 20
    • 48349097446 scopus 로고    scopus 로고
    • Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy
    • Hsu, K. F., Wu, C. L., Huang, S. C., Hsieh, J. L., Huang, Y. S., Chen, Y. F., Shen, M. R., Chung, W. J., Chou, C. Y. and Shiau, A. L. Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy. Cancer Gene Ther. 15 (2008) 526-534.
    • (2008) Cancer Gene Ther. , vol.15 , pp. 526-534
    • Hsu, K.F.1    Wu, C.L.2    Huang, S.C.3    Hsieh, J.L.4    Huang, Y.S.5    Chen, Y.F.6    Shen, M.R.7    Chung, W.J.8    Chou, C.Y.9    Shiau, A.L.10
  • 21
    • 77957958961 scopus 로고    scopus 로고
    • Addition of a single E2 binding site to the human papillomavirus (HPV) type 16 long control region enhances killing of HPV positive cells via HPV E2 protein-regulated herpes simplex virus type 1 thymidine kinase-mediated suicide gene therapy
    • Sharma, R. and Palefsky, J. M. Addition of a single E2 binding site to the human papillomavirus (HPV) type 16 long control region enhances killing of HPV positive cells via HPV E2 protein-regulated herpes simplex virus type 1 thymidine kinase-mediated suicide gene therapy. Hum. Gene Ther. 21 (2010) 843-854.
    • (2010) Hum. Gene Ther. , vol.21 , pp. 843-854
    • Sharma, R.1    Palefsky, J.M.2
  • 22
    • 0026691230 scopus 로고
    • Inhibition of tumorigenicity of cervical cancer cells in nude mice by HPV E6-E7 anti-sense RNA
    • von Knebel Doeberitz, M., Rittmuller, C., Zur Hausen, H. and Durst, M. Inhibition of tumorigenicity of cervical cancer cells in nude mice by HPV E6-E7 anti-sense RNA. Int. J. Cancer51 (1992) 831-834.
    • (1992) Int. J. Cancer , vol.51 , pp. 831-834
    • von Knebel Doeberitz, M.1    Rittmuller, C.2    Zur Hausen, H.3    Durst, M.4
  • 23
    • 0023116091 scopus 로고
    • Nucleotide sequence and comparative analysis of the human papillomavirus type 18 genome. Phylogeny of papillomaviruses and repeated structure of the E6 and E7 gene products
    • Cole, S. T. and Danos, O. Nucleotide sequence and comparative analysis of the human papillomavirus type 18 genome. Phylogeny of papillomaviruses and repeated structure of the E6 and E7 gene products. J. Mol. Biol. 193 (1987) 599-608.
    • (1987) J. Mol. Biol. , vol.193 , pp. 599-608
    • Cole, S.T.1    Danos, O.2
  • 24
    • 0023774522 scopus 로고
    • Interplay of viral and cellular proteins along the long control region of human papillomavirus type 18
    • Garcia-Carranca, A., Thierry, F. and Yaniv, M. Interplay of viral and cellular proteins along the long control region of human papillomavirus type 18. J. Virol. 62 (1988) 4321-4330.
    • (1988) J. Virol. , vol.62 , pp. 4321-4330
    • Garcia-Carranca, A.1    Thierry, F.2    Yaniv, M.3
  • 25
    • 0023837298 scopus 로고
    • Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18
    • Gius, D., Grossman, S., Bedell, M. A. and Laimins, L. A. Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18. J. Virol. 62 (1988) 665-672.
    • (1988) J. Virol. , vol.62 , pp. 665-672
    • Gius, D.1    Grossman, S.2    Bedell, M.A.3    Laimins, L.A.4
  • 26
    • 0026440998 scopus 로고
    • Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1
    • Bauknecht, T., Angel, P., Royer, H. D. and Zur Hausen, H. Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1. EMBO J. 11 (1992) 4607-4617.
    • (1992) EMBO J. , vol.11 , pp. 4607-4617
    • Bauknecht, T.1    Angel, P.2    Royer, H.D.3    Zur Hausen, H.4
  • 27
    • 0032489497 scopus 로고    scopus 로고
    • DNA structure and flexibility in the sequence-specific binding of papillomavirus E2 proteins
    • Hines, C. S., Meghoo, C., Shetty, S., Biburger, M., Brenowitz, M. and Hegde, R. S. DNA structure and flexibility in the sequence-specific binding of papillomavirus E2 proteins. J. Mol. Biol. 276 (1998) 809-818.
    • (1998) J. Mol. Biol. , vol.276 , pp. 809-818
    • Hines, C.S.1    Meghoo, C.2    Shetty, S.3    Biburger, M.4    Brenowitz, M.5    Hegde, R.S.6
  • 28
    • 0000557716 scopus 로고    scopus 로고
    • Human papillomavirus DNA replication compartments in a transient DNA replication system
    • Swindle, C. S., Zou, N., van Tine, B. A., Shaw, G. M., Engler, J. A. and Chow, L. T. Human papillomavirus DNA replication compartments in a transient DNA replication system. J. Virol. 73 (1999) 1001-1009.
    • (1999) J. Virol. , vol.73 , pp. 1001-1009
    • Swindle, C.S.1    Zou, N.2    van Tine, B.A.3    Shaw, G.M.4    Engler, J.A.5    Chow, L.T.6
  • 29
    • 0026558934 scopus 로고
    • During negative regulation of the human papillomavirus-16 E6 promoter, the viral E2 protein can displace Sp1 from a proximal promoter element
    • Tan, S. H., Gloss, B. and Bernard, H. U. During negative regulation of the human papillomavirus-16 E6 promoter, the viral E2 protein can displace Sp1 from a proximal promoter element. Nucleic Acids Res. 20 (1992) 251-256.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 251-256
    • Tan, S.H.1    Gloss, B.2    Bernard, H.U.3
  • 30
    • 59549085974 scopus 로고    scopus 로고
    • Transcriptional regulation of the papillomavirus oncogenes by cellular and viral transcription factors in cervical carcinoma
    • Thierry, F. Transcriptional regulation of the papillomavirus oncogenes by cellular and viral transcription factors in cervical carcinoma. Virology384 (2009) 375-379.
    • (2009) Virology , vol.384 , pp. 375-379
    • Thierry, F.1
  • 31
    • 0028833930 scopus 로고
    • Two E2 binding sites alone are sufficient to function as the minimal origin of replication of human papillomavirus type 18 DNA
    • Sverdrup, F. and Khan, S. A. Two E2 binding sites alone are sufficient to function as the minimal origin of replication of human papillomavirus type 18 DNA. J. Virol. 69 (1995) 1319-1323.
    • (1995) J. Virol. , vol.69 , pp. 1319-1323
    • Sverdrup, F.1    Khan, S.A.2
  • 32
    • 0036891226 scopus 로고    scopus 로고
    • Novel cellular interacting partners of the human papillomavirus 16 transcription/replication factor E2
    • Boner, W. and Morgan, I. M. Novel cellular interacting partners of the human papillomavirus 16 transcription/replication factor E2. Virus Res. 90 (2002) 113-118.
    • (2002) Virus Res. , vol.90 , pp. 113-118
    • Boner, W.1    Morgan, I.M.2
  • 33
    • 0028020627 scopus 로고
    • The E2 transcriptional repressor can compensate for Sp1 activation of the human papillomavirus type 18 early promoter
    • Demeret, C., Yaniv, M. and Thierry, F. The E2 transcriptional repressor can compensate for Sp1 activation of the human papillomavirus type 18 early promoter. J. Virol. 68 (1994) 7075-7082.
    • (1994) J. Virol. , vol.68 , pp. 7075-7082
    • Demeret, C.1    Yaniv, M.2    Thierry, F.3
  • 34
    • 0025953354 scopus 로고
    • The papillomavirus E2 regulatory proteins
    • McBride, A. A., Romanczuk, H. and Howley, P. M. The papillomavirus E2 regulatory proteins. J. Biol. Chem. 266 (1991) 18411-18414.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18411-18414
    • McBride, A.A.1    Romanczuk, H.2    Howley, P.M.3
  • 35
    • 80052447421 scopus 로고    scopus 로고
    • The E2 proteins
    • Los Alamos National Laboratory Bioscience Division
    • McBride, A. and Myers, G. (1997) The E2 proteins. The E2 proteins. Los Alamos National Laboratory Bioscience Division.
    • (1997) The E2 proteins
    • McBride, A.1    Myers, G.2
  • 37
    • 0027083517 scopus 로고
    • Activation of human papillomavirus type 18 E6-E7 oncogene expression by transcription factor Sp1
    • Hoppe-Seyler, F. and Butz, K. Activation of human papillomavirus type 18 E6-E7 oncogene expression by transcription factor Sp1. Nucleic Acids Res. 20 (1992) 6701-6706.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 6701-6706
    • Hoppe-Seyler, F.1    Butz, K.2
  • 38
    • 0025990183 scopus 로고
    • Repression of the human papillomavirus type 18 enhancer by the cellular transcription factor Oct-1
    • Hoppe-Seyler, F., Butz, K. and Zur Hausen, H. Repression of the human papillomavirus type 18 enhancer by the cellular transcription factor Oct-1. J. Virol. 65 (1991) 5613-5618.
    • (1991) J. Virol. , vol.65 , pp. 5613-5618
    • Hoppe-Seyler, F.1    Butz, K.2    Zur Hausen, H.3
  • 39
    • 0024429348 scopus 로고
    • The human papillomavirus type 18 (HPV18) E2 gene product is a repressor of the HPV18 regulatory region in human keratinocytes
    • Bernard, B. A., Bailly, C., Lenoir, M. C., Darmon, M., Thierry, F. and Yaniv, M. The human papillomavirus type 18 (HPV18) E2 gene product is a repressor of the HPV18 regulatory region in human keratinocytes. J. Virol. 63 (1989) 4317-4324.
    • (1989) J. Virol. , vol.63 , pp. 4317-4324
    • Bernard, B.A.1    Bailly, C.2    Lenoir, M.C.3    Darmon, M.4    Thierry, F.5    Yaniv, M.6
  • 40
    • 0037114361 scopus 로고    scopus 로고
    • The role of human papillomavirus oncoproteins E6 and E7 in apoptosis
    • Finzer, P., Aguilar-Lemarroy, A. and Rosl, F. The role of human papillomavirus oncoproteins E6 and E7 in apoptosis. Cancer Lett. 188 (2002) 15-24.
    • (2002) Cancer Lett. , vol.188 , pp. 15-24
    • Finzer, P.1    Aguilar-Lemarroy, A.2    Rosl, F.3
  • 41
    • 33645893204 scopus 로고    scopus 로고
    • Papillomaviruses as targets for cancer gene therapy
    • Shillitoe, E. J. Papillomaviruses as targets for cancer gene therapy. Cancer Gene Ther. 13 (2006) 445-450.
    • (2006) Cancer Gene Ther. , vol.13 , pp. 445-450
    • Shillitoe, E.J.1
  • 42
    • 0023178901 scopus 로고
    • Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product
    • Phelps, W. C. and Howley, P. M. Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product. J. Virol. 61 (1987) 1630-1638.
    • (1987) J. Virol. , vol.61 , pp. 1630-1638
    • Phelps, W.C.1    Howley, P.M.2
  • 43
    • 0024231822 scopus 로고
    • A dimer of BPV-1 E2 containing a protease resistant core interacts with its DNA target
    • Dostatni, N., Thierry, F. and Yaniv, M. A dimer of BPV-1 E2 containing a protease resistant core interacts with its DNA target. EMBO J. 7 (1988) 3807-3816.
    • (1988) EMBO J. , vol.7 , pp. 3807-3816
    • Dostatni, N.1    Thierry, F.2    Yaniv, M.3
  • 44
    • 0028039853 scopus 로고
    • Human papillomavirus type 11 E2 proteins repress the homologous E6 promoter by interfering with the binding of host transcription factors to adjacent elements
    • Dong, G., Broker, T. R. and Chow, L. T. Human papillomavirus type 11 E2 proteins repress the homologous E6 promoter by interfering with the binding of host transcription factors to adjacent elements. J. Virol. 68 (1994) 1115-1127.
    • (1994) J. Virol. , vol.68 , pp. 1115-1127
    • Dong, G.1    Broker, T.R.2    Chow, L.T.3
  • 45
    • 0025950547 scopus 로고
    • The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex
    • Dostatni, N., Lambert, P. F., Sousa, R., Ham, J., Howley, P. M. and Yaniv, M. The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex. Genes Dev. 5 (1991) 1657-1671.
    • (1991) Genes Dev. , vol.5 , pp. 1657-1671
    • Dostatni, N.1    Lambert, P.F.2    Sousa, R.3    Ham, J.4    Howley, P.M.5    Yaniv, M.6
  • 46
    • 33748159277 scopus 로고    scopus 로고
    • Gene expression profiles reveal an upregulation of E2F and downregulation of interferon targets by HPV18 but no changes between keratinocytes with integrated or episomal viral genomes
    • Karstensen, B., Poppelreuther, S., Bonin, M., Walter, M., Iftner, T. and Stubenrauch, F. Gene expression profiles reveal an upregulation of E2F and downregulation of interferon targets by HPV18 but no changes between keratinocytes with integrated or episomal viral genomes. Virology353 (2006) 200-209.
    • (2006) Virology , vol.353 , pp. 200-209
    • Karstensen, B.1    Poppelreuther, S.2    Bonin, M.3    Walter, M.4    Iftner, T.5    Stubenrauch, F.6
  • 48
    • 70450223323 scopus 로고    scopus 로고
    • Cell-type specific transcriptional activities among different papillomavirus long control regions and their regulation by E2
    • Ottinger, M., Smith, J. A., Schweiger, M. R., Robbins, D., Powell, M. L., You, J. and Howley, P. M. Cell-type specific transcriptional activities among different papillomavirus long control regions and their regulation by E2. Virology395 (2009) 161-171.
    • (2009) Virology , vol.395 , pp. 161-171
    • Ottinger, M.1    Smith, J.A.2    Schweiger, M.R.3    Robbins, D.4    Powell, M.L.5    You, J.6    Howley, P.M.7
  • 49
    • 77956633936 scopus 로고    scopus 로고
    • The E2F5 repressor is an activator of E6/E7 transcription and of the S-phase entry in HPV18-associated cells
    • Teissier, S., Pang, C. L. and Thierry, F. The E2F5 repressor is an activator of E6/E7 transcription and of the S-phase entry in HPV18-associated cells. Oncogene29 (2010) 5061-5070.
    • (2010) Oncogene , vol.29 , pp. 5061-5070
    • Teissier, S.1    Pang, C.L.2    Thierry, F.3
  • 51
    • 69449100234 scopus 로고    scopus 로고
    • Interferon-beta treatment increases human papillomavirus early gene transcription and viral plasmid genome replication by activating interferon regulatory factor (IRF)-1
    • Lace, M. J., Anson, J. R., Klingelhutz, A. J., Harada, H., Taniguchi, T., Bossler, A. D., Haugen, T. H. and Turek, L. P. Interferon-beta treatment increases human papillomavirus early gene transcription and viral plasmid genome replication by activating interferon regulatory factor (IRF)-1. Carcinogenesis30 (2009) 1336-1344.
    • (2009) Carcinogenesis , vol.30 , pp. 1336-1344
    • Lace, M.J.1    Anson, J.R.2    Klingelhutz, A.J.3    Harada, H.4    Taniguchi, T.5    Bossler, A.D.6    Haugen, T.H.7    Turek, L.P.8
  • 52
    • 55249103186 scopus 로고    scopus 로고
    • Functional mapping of the human papillomavirus type 16 E1 cistron
    • Lace, M. J., Anson, J. R., Turek, L. P. and Haugen, T. H. Functional mapping of the human papillomavirus type 16 E1 cistron. J. Virol. 82 (2008) 10724-10734.
    • (2008) J. Virol. , vol.82 , pp. 10724-10734
    • Lace, M.J.1    Anson, J.R.2    Turek, L.P.3    Haugen, T.H.4
  • 53
    • 67650928010 scopus 로고    scopus 로고
    • Upstream regulatory region alterations found in human papillomavirus type 16 (HPV-16) isolates from cervical carcinomas increase transcription, ori function, and HPV immortalization capacity in culture
    • Lace, M. J., Isacson, C., Anson, J. R., Lorincz, A. T., Wilczynski, S. P., Haugen, T. H. and Turek, L. P. Upstream regulatory region alterations found in human papillomavirus type 16 (HPV-16) isolates from cervical carcinomas increase transcription, ori function, and HPV immortalization capacity in culture. J. Virol. 83 (2009) 7457-7466.
    • (2009) J. Virol. , vol.83 , pp. 7457-7466
    • Lace, M.J.1    Isacson, C.2    Anson, J.R.3    Lorincz, A.T.4    Wilczynski, S.P.5    Haugen, T.H.6    Turek, L.P.7
  • 54
    • 77249119657 scopus 로고    scopus 로고
    • Interferon regulatory factor (IRF)-2 activates the HPV-16 E6-E7 promoter in keratinocytes
    • Lace, M. J., Anson, J. R., Haugen, T. H. and Turek, L. P. Interferon regulatory factor (IRF)-2 activates the HPV-16 E6-E7 promoter in keratinocytes. Virology399 (2010) 270-279.
    • (2010) Virology , vol.399 , pp. 270-279
    • Lace, M.J.1    Anson, J.R.2    Haugen, T.H.3    Turek, L.P.4
  • 56
    • 0034163475 scopus 로고    scopus 로고
    • Strength and specificity of different gene promoters in oral cancer cells
    • Shillitoe, E. J. and Noonan, S. Strength and specificity of different gene promoters in oral cancer cells. Oral Oncol. 36 (2000) 214-220.
    • (2000) Oral Oncol. , vol.36 , pp. 214-220
    • Shillitoe, E.J.1    Noonan, S.2
  • 57
    • 73149098714 scopus 로고    scopus 로고
    • A novel two-step transcriptional activation system for gene therapy directed toward epithelial cells
    • Arendt, M. L., Nasir, L. and Morgan, I. M. A novel two-step transcriptional activation system for gene therapy directed toward epithelial cells. Mol. Cancer Ther. 8 (2009) 3244-3254.
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 3244-3254
    • Arendt, M.L.1    Nasir, L.2    Morgan, I.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.