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Volumn 8, Issue 12, 2009, Pages 3244-3254

A novel two-step transcriptional activation system for gene therapy directed toward epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

GAL4 VP16 PROTEIN; GLYCOPROTEIN E2; HYBRID PROTEIN; PROTEIN VP16; RNA; RNA DIRECTED DNA POLYMERASE; TELOMERASE; TRANSCRIPTION FACTOR GAL4; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; VP16 E2 FUSION PROTEIN;

EID: 73149098714     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-09-0543     Document Type: Article
Times cited : (6)

References (26)
  • 1
    • 25144469762 scopus 로고    scopus 로고
    • Cancer-specific gene therapy
    • Lo HW, Day CP, Hung MC. Cancer-specific gene therapy. Adv Genet 2005;54:235-55.
    • (2005) Adv Genet , vol.54 , pp. 235-255
    • Lo, H.W.1    Day, C.P.2    Hung, M.C.3
  • 2
    • 0018376559 scopus 로고
    • Constitutive synthesis of the GAL4 protein, a galactose pathway regulator in Saccharomyces cerevisiae
    • Perlman D, Hopper JE. Constitutive synthesis of the GAL4 protein, a galactose pathway regulator in Saccharomyces cerevisiae. Cell 1979;16:89-95.
    • (1979) Cell , vol.16 , pp. 89-95
    • Perlman, D.1    Hopper, J.E.2
  • 3
    • 0023697252 scopus 로고
    • GAL4-VP16 is an unusually potent transcriptional activator
    • Sadowski I, Ma J, Triezenberg S, Ptashne M. GAL4-VP16 is an unusually potent transcriptional activator. Nature 1988;335:563-4.
    • (1988) Nature , vol.335 , pp. 563-564
    • Sadowski, I.1    Ma, J.2    Triezenberg, S.3    Ptashne, M.4
  • 4
    • 0035807838 scopus 로고    scopus 로고
    • Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters
    • Iyer M, Wu L, Carey M, Wang Y, Smallwood A, Gambhir SS. Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters. Proc Natl Acad Sci U S A 2001;98:14595-600.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14595-14600
    • Iyer, M.1    Wu, L.2    Carey, M.3    Wang, Y.4    Smallwood, A.5    Gambhir, S.S.6
  • 5
    • 15044363143 scopus 로고    scopus 로고
    • Non-invasive imaging of a transgenic mouse model using a prostate-specific two-step transcriptional amplification strategy
    • Iyer M, Salazar FB, Lewis X, et al. Non-invasive imaging of a transgenic mouse model using a prostate-specific two-step transcriptional amplification strategy. Transgenic Res 2005;14:47-55.
    • (2005) Transgenic Res , vol.14 , pp. 47-55
    • Iyer, M.1    Salazar, F.B.2    Lewis, X.3
  • 6
    • 0036192826 scopus 로고    scopus 로고
    • Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer
    • Zhang L, Adams JY, Billick E, et al. Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer. Mol Ther 2002;5:223-32.
    • (2002) Mol Ther , vol.5 , pp. 223-232
    • Zhang, L.1    Adams, J.Y.2    Billick, E.3
  • 7
    • 33745620050 scopus 로고    scopus 로고
    • Two-step transcriptional amplification-lipid-based nanoparticles using PSMA or midkine promoter for suicide gene therapy in prostate cancer
    • Hattori Y, Maitani Y. Two-step transcriptional amplification-lipid-based nanoparticles using PSMA or midkine promoter for suicide gene therapy in prostate cancer. Cancer Sci 2006;97:787-98.
    • (2006) Cancer Sci , vol.97 , pp. 787-798
    • Hattori, Y.1    Maitani, Y.2
  • 8
    • 33847020818 scopus 로고    scopus 로고
    • Two-step amplification of the human PPT sequence provides specific gene expression in an immunocompetent murine prostate cancer model
    • Dzojic H, Cheng WS, Essand M. Two-step amplification of the human PPT sequence provides specific gene expression in an immunocompetent murine prostate cancer model. Cancer Gene Ther 2007;14:233-40.
    • (2007) Cancer Gene Ther , vol.14 , pp. 233-240
    • Dzojic, H.1    Cheng, W.S.2    Essand, M.3
  • 9
    • 0034989410 scopus 로고    scopus 로고
    • Augmenting transgene expression from carcinoembryonic antigen (CEA) promoter via a GAL4 gene regulatory system
    • Koch PE, Guo ZS, Kagawa S, Gu J, Roth JA, Fang B. Augmenting transgene expression from carcinoembryonic antigen (CEA) promoter via a GAL4 gene regulatory system. Mol Ther 2001;3:278-83.
    • (2001) Mol Ther , vol.3 , pp. 278-283
    • Koch, P.E.1    Guo, Z.S.2    Kagawa, S.3    Gu, J.4    Roth, J.A.5    Fang, B.6
  • 10
    • 33645790767 scopus 로고    scopus 로고
    • Noninvasive indirect imaging of vascular endothelial growth factor gene expression using bioluminescence imaging in living transgenic mice
    • Wang Y, Iyer M, Annala A, Wu L, Carey M, Gambhir SS. Noninvasive indirect imaging of vascular endothelial growth factor gene expression using bioluminescence imaging in living transgenic mice. Physiol Genomics 2006;24:173-80.
    • (2006) Physiol Genomics , vol.24 , pp. 173-180
    • Wang, Y.1    Iyer, M.2    Annala, A.3    Wu, L.4    Carey, M.5    Gambhir, S.S.6
  • 11
    • 54949096930 scopus 로고    scopus 로고
    • Noninvasive imaging of therapeutic gene expression using a bidirectional transcriptional amplification strategy
    • Ray S, Paulmurugan R, Patel MR, et al. Noninvasive imaging of therapeutic gene expression using a bidirectional transcriptional amplification strategy. Mol Ther 2008;16:1848-56.
    • (2008) Mol Ther , vol.16 , pp. 1848-1856
    • Ray, S.1    Paulmurugan, R.2    Patel, M.R.3
  • 12
    • 33750996986 scopus 로고    scopus 로고
    • Gal4-NF-κB fusion protein augments transgene expression from neuronal promoters in the rat brain
    • Liu BH, Yang Y, Paton JF, et al. Gal4-NF-κB fusion protein augments transgene expression from neuronal promoters in the rat brain. Mol Ther 2006;14:872-82.
    • (2006) Mol Ther , vol.14 , pp. 872-882
    • Liu, B.H.1    Yang, Y.2    Paton, J.F.3
  • 13
    • 33750345199 scopus 로고    scopus 로고
    • Lee M, Oh S, Ahn CH, Kim SW, Rhee BD, Ko KS. An efficient GLP-1 expression system using two-step transcription amplification. J Control Release 2006;115:316-21
    • Lee M, Oh S, Ahn CH, Kim SW, Rhee BD, Ko KS. An efficient GLP-1 expression system using two-step transcription amplification. J Control Release 2006;115:316-21.
  • 14
    • 1642576197 scopus 로고    scopus 로고
    • Development of a cancer-targeted tissue-specific promoter system
    • Fukazawa T, Maeda Y, Sladek FM, Owen-Schaub LB. Development of a cancer-targeted tissue-specific promoter system. Cancer Res 2004;64:363-69.
    • (2004) Cancer Res , vol.64 , pp. 363-369
    • Fukazawa, T.1    Maeda, Y.2    Sladek, F.M.3    Owen-Schaub, L.B.4
  • 15
    • 3142770344 scopus 로고    scopus 로고
    • Novel bidirectional vector strategy for amplification of therapeutic and reporter gene expression
    • Ray S, Paulmurugan R, Hildebrandt I, et al. Novel bidirectional vector strategy for amplification of therapeutic and reporter gene expression. Hum Gene Ther 2004;15:681-90.
    • (2004) Hum Gene Ther , vol.15 , pp. 681-690
    • Ray, S.1    Paulmurugan, R.2    Hildebrandt, I.3
  • 16
    • 4444252923 scopus 로고    scopus 로고
    • Noninvasive imaging of enhanced prostate-specific gene expression using a two-step transcriptional amplification-based lentivirus vector
    • Iyer M, Salazar FB, Lewis X, et al. Noninvasive imaging of enhanced prostate-specific gene expression using a two-step transcriptional amplification-based lentivirus vector. Mol Ther 2004;10:545-52.
    • (2004) Mol Ther , vol.10 , pp. 545-552
    • Iyer, M.1    Salazar, F.B.2    Lewis, X.3
  • 17
    • 0348133605 scopus 로고    scopus 로고
    • Optimization of adenoviral vectors to direct highly amplified prostate-specific expression for imaging and gene therapy
    • Sato M, Johnson M, Zhang L, et al. Optimization of adenoviral vectors to direct highly amplified prostate-specific expression for imaging and gene therapy. Mol Ther 2003;8:726-37.
    • (2003) Mol Ther , vol.8 , pp. 726-737
    • Sato, M.1    Johnson, M.2    Zhang, L.3
  • 18
    • 43049165871 scopus 로고    scopus 로고
    • Configurations of a two-tiered amplified gene expression system in adenoviral vectors designed to improve the specificity of in vivo prostate cancer imaging
    • Sato M, Figueiredo ML, Burton JB, et al. Configurations of a two-tiered amplified gene expression system in adenoviral vectors designed to improve the specificity of in vivo prostate cancer imaging. Gene Ther 2008;15:583-93.
    • (2008) Gene Ther , vol.15 , pp. 583-593
    • Sato, M.1    Figueiredo, M.L.2    Burton, J.B.3
  • 19
    • 49149086250 scopus 로고    scopus 로고
    • Adenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer
    • Burton JB, Johnson M, Sato M, et al. Adenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer. Nat Med 2008;14:882-8.
    • (2008) Nat Med , vol.14 , pp. 882-888
    • Burton, J.B.1    Johnson, M.2    Sato, M.3
  • 20
    • 0029833154 scopus 로고    scopus 로고
    • E2 proteins: Modulators of papillomavirus transcription and replication
    • Steger G, Ham J, Yaniv M. E2 proteins: modulators of papillomavirus transcription and replication. Methods Enzymol 1996;274:173-85.
    • (1996) Methods Enzymol , vol.274 , pp. 173-185
    • Steger, G.1    Ham, J.2    Yaniv, M.3
  • 21
    • 39749163359 scopus 로고    scopus 로고
    • Telomerase and cancer therapeutics
    • Harley CB. Telomerase and cancer therapeutics. Nat Rev Cancer 2008;8:167-79.
    • (2008) Nat Rev Cancer , vol.8 , pp. 167-179
    • Harley, C.B.1
  • 22
    • 0033600743 scopus 로고    scopus 로고
    • An enhanced epithelial response of a papillomavirus promoter to transcriptional activators
    • Vance KW, Campo MS, Morgan IM. An enhanced epithelial response of a papillomavirus promoter to transcriptional activators. J Biol Chem 1999;274:27839-44.
    • (1999) J Biol Chem , vol.274 , pp. 27839-27844
    • Vance, K.W.1    Campo, M.S.2    Morgan, I.M.3
  • 23
    • 0035120371 scopus 로고    scopus 로고
    • A novel silencer element in the bovine papillomavirus type 4 promoter represses the transcriptional response to papillomavirus E2 protein
    • Vance KW, Campo MS, Morgan IM. A novel silencer element in the bovine papillomavirus type 4 promoter represses the transcriptional response to papillomavirus E2 protein. J Virol 2001;75:2829-38.
    • (2001) J Virol , vol.75 , pp. 2829-2838
    • Vance, K.W.1    Campo, M.S.2    Morgan, I.M.3
  • 24
    • 0035936001 scopus 로고    scopus 로고
    • Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954
    • Plumb JA, Bilsland A, Kakani R, et al. Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954. Oncogene 2001;20:7797-803.
    • (2001) Oncogene , vol.20 , pp. 7797-7803
    • Plumb, J.A.1    Bilsland, A.2    Kakani, R.3
  • 25
    • 2542423588 scopus 로고    scopus 로고
    • Casein kinase II phosphorylation-induced conformational switch triggers degradation of the papillomavirus E2 protein
    • Penrose KJ, Garcia-Alai M, de Prat-Gay G, McBride AA. Casein kinase II phosphorylation-induced conformational switch triggers degradation of the papillomavirus E2 protein. J Biol Chem 2004;279:22430-9.
    • (2004) J Biol Chem , vol.279 , pp. 22430-22439
    • Penrose, K.J.1    Garcia-Alai, M.2    de Prat-Gay, G.3    McBride, A.A.4
  • 26
    • 33847074257 scopus 로고    scopus 로고
    • Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses
    • Bilsland AE, Merron A, Vassaux G, Keith WN. Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses. Cancer Res 2007;67:1299-307.
    • (2007) Cancer Res , vol.67 , pp. 1299-1307
    • Bilsland, A.E.1    Merron, A.2    Vassaux, G.3    Keith, W.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.