Complement regulates CD4 T-cell help to CD8 T cells required for murine allograft rejection

American Journal of Pathology

Volumn 179, Issue 2, 2011, Pages 766-774

  Vieyra, Mark ^a   Leisman, Staci ^a   Raedler, Hugo ^a   Kwan, Wing Hong ^a   Yang, Min ^a   Strainic, Michael G ^b   Medof, M Edward ^b   Heeger, Peter S ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CARDIAC GRAFT REJECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INTERACTION; DENDRITIC CELL; HEART GRAFT; IMMUNOCOMPETENT CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; WILD TYPE;

ANIMALS; ANTIGENS, CD40; BONE MARROW CELLS; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; COMPLEMENT C3A; COMPLEMENT C5A; COMPLEMENT SYSTEM PROTEINS; CROSSES, GENETIC; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRAFT REJECTION; HEART TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 80052430849     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.04.038     Document Type: Article

References (32)

1. A.S. Rosenberg, T.I. Munitz, T.G. Maniero, and A. Singer Cellular basis of skin allograft rejection across a class I major histocompatibility barrier in mice depleted of CD8+ T cells in vivo J Exp Med 173 1991 1463 1471
2. A.S. Rosenberg, T. Mizuochi, and A. Singer Cellular interactions resulting in skin-allograft rejection Ann N Y Acad Sci 532 1988 76 85 (Pubitemid 19017629)
3. A.S. Rosenberg, T. Mizuochi, S.O. Sharrow, and A. Singer Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection J Exp Med 165 1987 1296 1315 (Pubitemid 17073529)
4. S.Y. Chan, L.A. DeBruyne, R.E. Goodman, E.J. Eichwald, and D.K. Bishop In vivo depletion of CD8+ T cells results in Th2 cytokine production and alternate mechanisms of allograft rejection Transplantation 59 1995 1155 1161
5. K.L. Csencsits, and D.K. Bishop Contrasting alloreactive CD4+ and CD8+ T cells: there's more to it than MHC restriction Am J Transplant 3 2003 107 115 (Pubitemid 36329127)
6. N.R. Krieger, D.P. Yin, and C.G. Fathman CD4+ but not CD8+ cells are essential for allorejection J Exp Med 184 1996 2013 2018 (Pubitemid 26404491)
7. I.S. Grewal, and R.A. Flavell The role of CD40 ligand in costimulation and T-cell activation Immunol Rev 153 1996 85 106 (Pubitemid 27010764)
8. J.P. Ridge, F. Di Rosa, and P. Matzinger A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell Nature 393 1998 474 478
9. S.P. Schoenberger, R.E. Toes, E.I. van der Voort, R. Offringa, and C.J. Melief T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions Nature 393 1998 480 483
10. J.M. Curtsinger, C.M. Johnson, and M.F. Mescher CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine J Immunol 171 2003 5165 5171 (Pubitemid 37432800)
11. B.E. Burrell, G. Lu, X.C. Li, and D.K. Bishop OX40 costimulation prevents allograft acceptance induced by CD40-CD40L blockade J Immunol 182 2009 379 390
12. M.J. Nathan, J.E. Mold, S.C. Wood, K. Csencsits, G. Lu, E.J. Eichwald, and D.K. Bishop Requirement for donor and recipient CD40 expression in cardiac allograft rejection: induction of Th1 responses and influence of donor-derived dendritic cells J Immunol 172 2004 6626 6633 (Pubitemid 38669097)
13. M.P. Fischbein, A. Ardehali, J. Yun, S. Schoenberger, H. Laks, Y. Irie, P. Dempsey, G. Cheng, M.C. Fishbein, and B. Bonavida CD40 signaling replaces CD4+ lymphocytes and its blocking prevents chronic rejection of heart transplants J Immunol 165 2000 7316 7322 (Pubitemid 32001212)
14. M.G. Strainic, J. Liu, D. Huang, F. An, P.N. Lalli, N. Muqim, V.S. Shapiro, G.R. Dubyak, P.S. Heeger, and M.E. Medof Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells Immunity 28 2008 425 435
15. P.N. Lalli, M.G. Strainic, M. Yang, F. Lin, M.E. Medof, and P.S. Heeger Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis Blood 112 2008 1759 1766
16. P.S. Heeger, P.N. Lalli, F. Lin, A. Valujskikh, J. Liu, N. Muqim, Y. Xu, and M.E. Medof Decay-accelerating factor modulates induction of T cell immunity J Exp Med 201 2005 1523 1530 (Pubitemid 40720998)
17. F. Lin, Y. Fukuoka, A. Spicer, R. Ohta, N. Okada, C.L. Harris, S.N. Emancipator, and M.E. Medof Tissue distribution of products of the mouse decay-accelerating factor (DAF) genes Exploitation of a Daf1 knock-out mouse and site-specific monoclonal antibodies Immunology 104 2001 215 225 (Pubitemid 32989522)
18. P.N. Lalli, M.G. Strainic, F. Lin, M.E. Medof, and P.S. Heeger Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production J Immunol 179 2007 5793 5802
19. V. Pavlov, H. Raedler, S. Yuan, S. Leisman, W.H. Kwan, P.N. Lalli, M.E. Medof, and P.S. Heeger Donor deficiency of decay-accelerating factor accelerates murine T cell-mediated cardiac allograft rejection J Immunol 181 2008 4580 4589
20. H. Raedler, M. Yang, P.N. Lalli, M.E. Medof, and P.S. Heeger Primed CD8 T-cell responses to allogeneic endothelial cells are controlled by local complement activation Am J Transplant 9 2009 1784 1795
21. Y. Chen, Y. Demir, A. Valujskikh, and P.S. Heeger Antigen location contributes to the pathological features of a transplanted heart graft Am J Pathol 164 2004 1407 1415 (Pubitemid 38387806)
22. C. Fang, X. Zhang, T. Miwa, and W.C. Song Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production Blood 114 2009 1005 1015
23. J. Liu, F. Lin, M.G. Strainic, F. An, R.H. Miller, C.Z. Altuntas, P.S. Heeger, V.K. Tuohy, and M.E. Medof IFN-gamma and IL-17 production in experimental autoimmune encephalomyelitis depends on local APC-T cell complement production J Immunol 180 2008 5882 5889
24. J.E. Marsh, C.K. Farmer, S. Jurcevic, Y. Wang, M.C. Carroll, and S.H. Sacks The allogeneic T and B cell response is strongly dependent on complement components C3 and C4 Transplantation 72 2001 1310 1318 (Pubitemid 33026614)
25. M. Suresh, H. Molina, M.S. Salvato, D. Mastellos, J.D. Lambris, and M. Sandor Complement component 3 is required for optimal expansion of CD8 T cells during a systemic viral infection J Immunol 170 2003 788 794 (Pubitemid 36070530)
26. M. Kopf, B. Abel, A. Gallimore, M. Carroll, and M.F. Bachmann Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection Nat Med 8 2002 373 378 (Pubitemid 34407032)
27. C. Fang, T. Miwa, H. Shen, and W.C. Song Complement-dependent enhancement of CD8+ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice J Immunol 179 2007 3178 3186
28. G. Qiao, M. Lei, Z. Li, Y. Sun, A. Minto, Y.X. Fu, H. Ying, R.J. Quigg, and J. Zhang Negative regulation of CD40-mediated B cell responses by E3 ubiquitin ligase Casitas-B-lineage lymphoma protein-B J Immunol 179 2007 4473 4479
29. S.H. Hanissian, and R.S. Geha Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells Immunity 6 1997 379 387 (Pubitemid 27208193)
30. P. Revy, C. Hivroz, G. Andreu, P. Graber, C. Martinache, A. Fischer, and A. Durandy Activation of the Janus kinase 3-STAT5a pathway after CD40 triggering of human monocytes but not of resting B cells J Immunol 163 1999 787 793 (Pubitemid 29328086)
31. R. Elgueta, M.J. Benson, V.C. de Vries, A. Wasiuk, Y. Guo, and R.J. Noelle Molecular mechanism and function of CD40/CD40L engagement in the immune system Immunol Rev 229 2009 152 172
32. E.J. Wherry, S.J. Ha, S.M. Kaech, W.N. Haining, S. Sarkar, V. Kalia, S. Subramaniam, J.N. Blattman, D.L. Barber, and R. Ahmed Molecular signature of CD8+ T cell exhaustion during chronic viral infection Immunity 27 2007 670 684 (Pubitemid 47615511)