Programmed death-1 pathway limits central nervous system inflammation and neurologic deficits in murine experimental stroke

Stroke

Volumn 42, Issue 9, 2011, Pages 2578-2583

  Ren, Xuefang ^a,b   Akiyoshi, Kozaburo ^b,c   Vandenbark, Arthur A ^a,b   Hurn, Patricia D ^b   Offner, Halina ^a,b  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c KYUSHU UNIVERSITY HOSPITAL   (Japan)

Author keywords

coinhibitory pathway; inflammatory cells; MCAO; programmed death 1

Indexed keywords

CD19 ANTIGEN; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; PROGRAMMED DEATH 1 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BRAIN INFARCTION SIZE; CELL INFILTRATION; CELL POPULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE EXACERBATION; IMMUNOCOMPETENT CELL; INFLAMMATION; MACROPHAGE ACTIVATION; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPLEEN; STROKE; T LYMPHOCYTE; UPREGULATION;

ANIMALS; ANTIGENS, CD80; ANTIGENS, SURFACE; APOPTOSIS REGULATORY PROTEINS; B-LYMPHOCYTES; BRAIN INFARCTION; DISEASE MODELS, ANIMAL; INFLAMMATION; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MICROGLIA; PEPTIDES; SIGNAL TRANSDUCTION; STROKE; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 80052423806     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.613182     Document Type: Article

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