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Volumn 129, Issue 2, 2011, Pages 85-94

Echinococcus multilocularis: Molecular characterization of EmSmadE, a novel BR-Smad involved in TGF-β and BMP signaling

Author keywords

BMP; Cestode; Development; Echinococcus; Smad; TGF

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; COMPLEMENTARY DNA; EMSMADA PROTEIN; EMSMADB PROTEIN; EMSMADD PROTEIN; EMSMADE PROTEIN; HETERODIMER; HOMODIMER; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG;

EID: 80052416877     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2011.07.013     Document Type: Article
Times cited : (14)

References (45)
  • 2
    • 0035943697 scopus 로고    scopus 로고
    • Human transforming growth factor-β activates a receptor serine/threonine kinase from the intravascular parasite Schistosoma mansoni
    • Beall M.J., Pearce E.J. Human transforming growth factor-β activates a receptor serine/threonine kinase from the intravascular parasite Schistosoma mansoni. Journal of Biological Chemistry 2001, 276:31613-31619.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 31613-31619
    • Beall, M.J.1    Pearce, E.J.2
  • 6
    • 0033006930 scopus 로고    scopus 로고
    • Characterization of the genomic locus expressing the ERM-like protein of Echinococcus multilocularis
    • Brehm K., Jensen K., Frosch P., Frosch M. Characterization of the genomic locus expressing the ERM-like protein of Echinococcus multilocularis. Molecular and Biochemical Parasitology 1999, 100:147-152.
    • (1999) Molecular and Biochemical Parasitology , vol.100 , pp. 147-152
    • Brehm, K.1    Jensen, K.2    Frosch, P.3    Frosch, M.4
  • 7
    • 0041825108 scopus 로고    scopus 로고
    • Analysis of differential gene expression in Echinococcus multilocularis larval stages by means of spliced leader differential display
    • Brehm K., Wolf M., Beland H., Kroner A., Frosch M. Analysis of differential gene expression in Echinococcus multilocularis larval stages by means of spliced leader differential display. International Journal for Parasitology 2003, 33:1145-1159.
    • (2003) International Journal for Parasitology , vol.33 , pp. 1145-1159
    • Brehm, K.1    Wolf, M.2    Beland, H.3    Kroner, A.4    Frosch, M.5
  • 9
    • 46749097155 scopus 로고    scopus 로고
    • Recent advances in the in vitro cultivation and genetic manipulation of Echinococcus multilocularis metacestodes and germinal cells
    • Brehm K., Spiliotis M. Recent advances in the in vitro cultivation and genetic manipulation of Echinococcus multilocularis metacestodes and germinal cells. Experimental Parasitology 2008, 119:506-515.
    • (2008) Experimental Parasitology , vol.119 , pp. 506-515
    • Brehm, K.1    Spiliotis, M.2
  • 10
    • 77949656573 scopus 로고    scopus 로고
    • Echinococcus multilocularis as an experimental model in stem cell research and molecular host-parasite interaction
    • Brehm K. Echinococcus multilocularis as an experimental model in stem cell research and molecular host-parasite interaction. Parasitology 2010, 137:537-555.
    • (2010) Parasitology , vol.137 , pp. 537-555
    • Brehm, K.1
  • 11
    • 77955550523 scopus 로고    scopus 로고
    • The role of evolutionarily conserved signalling systems in Echinococcus multilocularis development and host-parasite interaction
    • Brehm K. The role of evolutionarily conserved signalling systems in Echinococcus multilocularis development and host-parasite interaction. Medical Microbiology and Immunology 2010, 199:247-259.
    • (2010) Medical Microbiology and Immunology , vol.199 , pp. 247-259
    • Brehm, K.1
  • 14
    • 2942620640 scopus 로고    scopus 로고
    • Tegumental expression of a novel type II receptor serine/threonine kinase (SmRK2) in Schistosoma mansoni
    • Forrester S.G., Warfel P.W., Pearce E.J. Tegumental expression of a novel type II receptor serine/threonine kinase (SmRK2) in Schistosoma mansoni. Molecular and Biochemical Parasitology 2004, 136:149-156.
    • (2004) Molecular and Biochemical Parasitology , vol.136 , pp. 149-156
    • Forrester, S.G.1    Warfel, P.W.2    Pearce, E.J.3
  • 15
    • 79954504855 scopus 로고    scopus 로고
    • Molecular characterisation of a serum-responsive, DAF-12-like nuclear hormone receptor of the fox-tapeworm Echinococcus multilocularis
    • Förster S., Günthel D., Kiss F., Brehm K. Molecular characterisation of a serum-responsive, DAF-12-like nuclear hormone receptor of the fox-tapeworm Echinococcus multilocularis. Journal of Cellular Biochemistry 2011, 112:1630-1642.
    • (2011) Journal of Cellular Biochemistry , vol.112 , pp. 1630-1642
    • Förster, S.1    Günthel, D.2    Kiss, F.3    Brehm, K.4
  • 16
    • 34250689543 scopus 로고    scopus 로고
    • TGF-β signaling controls embryo development in the parasitic flatworm Schistosoma mansoni
    • Freitas T.C., Jung E., Pearce E.J. TGF-β signaling controls embryo development in the parasitic flatworm Schistosoma mansoni. PLoS Pathogens 2007, 3:e52.
    • (2007) PLoS Pathogens , vol.3
    • Freitas, T.C.1    Jung, E.2    Pearce, E.J.3
  • 17
    • 58549119947 scopus 로고    scopus 로고
    • A bone morphogenetic protein homologue in the parasitic flatworm, Schistosoma mansoni
    • Freitas T.C., Jung E., Pearce E.J. A bone morphogenetic protein homologue in the parasitic flatworm, Schistosoma mansoni. International Journal for Parasitology 2009, 39:281-287.
    • (2009) International Journal for Parasitology , vol.39 , pp. 281-287
    • Freitas, T.C.1    Jung, E.2    Pearce, E.J.3
  • 18
    • 0033768824 scopus 로고    scopus 로고
    • Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution
    • Funaba M., Mathews L.S. Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution. Molecular Endocrinology 2000, 14:1583-1591.
    • (2000) Molecular Endocrinology , vol.14 , pp. 1583-1591
    • Funaba, M.1    Mathews, L.S.2
  • 19
    • 79951771552 scopus 로고    scopus 로고
    • A Bmp/Admp regulatory circuit controls maintenance and regeneration of dorsal-ventral polarity in planarians
    • Gavino M.A., Reddien P.W. A Bmp/Admp regulatory circuit controls maintenance and regeneration of dorsal-ventral polarity in planarians. Current Biology 2011, 21:294-299.
    • (2011) Current Biology , vol.21 , pp. 294-299
    • Gavino, M.A.1    Reddien, P.W.2
  • 20
    • 24644524014 scopus 로고    scopus 로고
    • Echinococcus multilocularis: cloning and characterization of a member of the SNW/SKIP family of transcriptional coregulators
    • Gelmedin V., Zavala-Gongora R., Fernandez C., Brehm K. Echinococcus multilocularis: cloning and characterization of a member of the SNW/SKIP family of transcriptional coregulators. Experimental Parasitology 2005, 111:115-120.
    • (2005) Experimental Parasitology , vol.111 , pp. 115-120
    • Gelmedin, V.1    Zavala-Gongora, R.2    Fernandez, C.3    Brehm, K.4
  • 21
    • 77950022749 scopus 로고    scopus 로고
    • Molecular characterisation of MEK1/2- and MKK3/6-like mitogen-activated protein kinase kinases (MAPKK) from the fox tapeworm Echinococcus multilocularis
    • Gelmedin V., Spiliotis M., Brehm K. Molecular characterisation of MEK1/2- and MKK3/6-like mitogen-activated protein kinase kinases (MAPKK) from the fox tapeworm Echinococcus multilocularis. International Journal for Parasitology 2010, 40:555-567.
    • (2010) International Journal for Parasitology , vol.40 , pp. 555-567
    • Gelmedin, V.1    Spiliotis, M.2    Brehm, K.3
  • 23
    • 0034533657 scopus 로고    scopus 로고
    • Signaling of transforming growth factor-β family members through Smad proteins
    • Itoh S., Itoh F., Goumans M.J., Ten Dijke P. Signaling of transforming growth factor-β family members through Smad proteins. European Journal of Biochemistry 2000, 267:6954-6967.
    • (2000) European Journal of Biochemistry , vol.267 , pp. 6954-6967
    • Itoh, S.1    Itoh, F.2    Goumans, M.J.3    Ten Dijke, P.4
  • 24
    • 35448990369 scopus 로고    scopus 로고
    • Tyrosine kinase and cooperative TGFβ signaling in the reproductive organs of Schistosoma mansoni
    • Knobloch J., Beckmann S., Burmeister C., Quack T., Grevelding C.G. Tyrosine kinase and cooperative TGFβ signaling in the reproductive organs of Schistosoma mansoni. Experimental Parasitology 2007, 117:318-336.
    • (2007) Experimental Parasitology , vol.117 , pp. 318-336
    • Knobloch, J.1    Beckmann, S.2    Burmeister, C.3    Quack, T.4    Grevelding, C.G.5
  • 26
    • 0037350035 scopus 로고    scopus 로고
    • Identification and molecular characterisation of a gene encoding a member of the insulin receptor family in Echinococcus multilocularis
    • Konrad C., Kroner A., Spiliotis M., Zavala-Gongora R., Brehm K. Identification and molecular characterisation of a gene encoding a member of the insulin receptor family in Echinococcus multilocularis. International Journal of Parasitology 2003, 33:301-312.
    • (2003) International Journal of Parasitology , vol.33 , pp. 301-312
    • Konrad, C.1    Kroner, A.2    Spiliotis, M.3    Zavala-Gongora, R.4    Brehm, K.5
  • 27
    • 0032481351 scopus 로고    scopus 로고
    • The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-β receptors
    • Lo R.S., Chen Y.G., Shi Y., Pavletich N.P., Massague J. The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-β receptors. EMBO Journal 1998, 17:996-1005.
    • (1998) EMBO Journal , vol.17 , pp. 996-1005
    • Lo, R.S.1    Chen, Y.G.2    Shi, Y.3    Pavletich, N.P.4    Massague, J.5
  • 29
    • 77954569645 scopus 로고    scopus 로고
    • Echinococcosis with particular reference to Southeast Asia
    • McManus D.P. Echinococcosis with particular reference to Southeast Asia. Advances in Parasitology 2010, 72:267-303.
    • (2010) Advances in Parasitology , vol.72 , pp. 267-303
    • McManus, D.P.1
  • 30
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of TGFβ signal transduction
    • Moustakas A., Heldin C.H. The regulation of TGFβ signal transduction. Development 2009, 136:3699-3714.
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.H.2
  • 31
    • 0035971223 scopus 로고    scopus 로고
    • Identification and characterization of a Smad2 homologue from Schistosoma mansoni, a transforming growth factor-β signal transducer
    • Osman A., Niles E.G., LoVerde P.T. Identification and characterization of a Smad2 homologue from Schistosoma mansoni, a transforming growth factor-β signal transducer. Journal of Biological Chemistry 2001, 276:10072-10082.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 10072-10082
    • Osman, A.1    Niles, E.G.2    LoVerde, P.T.3
  • 32
    • 1342282987 scopus 로고    scopus 로고
    • Expression of functional Schistosoma mansoni Smad4: role in Erk-mediated transforming growth factor β (TGF-β) down-regulation
    • Osman A., Niles E.G., LoVerde P.T. Expression of functional Schistosoma mansoni Smad4: role in Erk-mediated transforming growth factor β (TGF-β) down-regulation. Journal of Biological Chemistry 2004, 279:6474-6486.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 6474-6486
    • Osman, A.1    Niles, E.G.2    LoVerde, P.T.3
  • 33
    • 33745684276 scopus 로고    scopus 로고
    • Schistosoma mansoni TGF-β receptor II: role in host ligand-induced regulation of a schistosome target gene
    • Osman A., Niles E.G., Verjovski-Almeida S., LoVerde P.T. Schistosoma mansoni TGF-β receptor II: role in host ligand-induced regulation of a schistosome target gene. PLoS Pathogens 2006, 2:e54.
    • (2006) PLoS Pathogens , vol.2
    • Osman, A.1    Niles, E.G.2    Verjovski-Almeida, S.3    LoVerde, P.T.4
  • 36
    • 0345059072 scopus 로고    scopus 로고
    • Identification, molecular characterization and expression of the gene encoding the epidermal growth factor receptor orthologue from the fox-tapeworm Echinococcus multilocularis
    • Spiliotis M., Kroner A., Brehm K. Identification, molecular characterization and expression of the gene encoding the epidermal growth factor receptor orthologue from the fox-tapeworm Echinococcus multilocularis. Gene 2003, 323:57-65.
    • (2003) Gene , vol.323 , pp. 57-65
    • Spiliotis, M.1    Kroner, A.2    Brehm, K.3
  • 37
    • 33747135696 scopus 로고    scopus 로고
    • Characterisation of EmMPK1, an ERK-like MAP kinase from Echinococcus multilocularis which is activated in response to human epidermal growth factor
    • Spiliotis M., Konrad C., Gelmedin V., Tappe D., Bruckner S., Mösch H.U., Brehm K. Characterisation of EmMPK1, an ERK-like MAP kinase from Echinococcus multilocularis which is activated in response to human epidermal growth factor. International Journal for Parasitology 2006, 36:1097-1112.
    • (2006) International Journal for Parasitology , vol.36 , pp. 1097-1112
    • Spiliotis, M.1    Konrad, C.2    Gelmedin, V.3    Tappe, D.4    Bruckner, S.5    Mösch, H.U.6    Brehm, K.7
  • 38
    • 43849097222 scopus 로고    scopus 로고
    • Transient transfection of Echinococcus multilocularis primary cells and complete in vitro regeneration of metacestode vesicles
    • Spiliotis M., Lechner S., Tappe D., Scheller C., Krohne G., Brehm K. Transient transfection of Echinococcus multilocularis primary cells and complete in vitro regeneration of metacestode vesicles. International Journal for Parasitology 2008, 38:1025-1039.
    • (2008) International Journal for Parasitology , vol.38 , pp. 1025-1039
    • Spiliotis, M.1    Lechner, S.2    Tappe, D.3    Scheller, C.4    Krohne, G.5    Brehm, K.6
  • 39
    • 59249083514 scopus 로고    scopus 로고
    • Axenic in vitro cultivation of Echinococcus multilocularis metacestode vesicles and the generation of primary cell cultures
    • Spiliotis M., Brehm K. Axenic in vitro cultivation of Echinococcus multilocularis metacestode vesicles and the generation of primary cell cultures. Methods in Molecular Biology 2009, 470:245-262.
    • (2009) Methods in Molecular Biology , vol.470 , pp. 245-262
    • Spiliotis, M.1    Brehm, K.2
  • 42
    • 0347664883 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of Smad1 conferred by its nuclear localization and nuclear export signals
    • Xiao Z., Watson N., Rodriguez C., Lodish H.F. Nucleocytoplasmic shuttling of Smad1 conferred by its nuclear localization and nuclear export signals. Journal of Biological Chemistry 2001, 276:39404-39410.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 39404-39410
    • Xiao, Z.1    Watson, N.2    Rodriguez, C.3    Lodish, H.F.4
  • 43
    • 0242551302 scopus 로고    scopus 로고
    • Identification and characterisation of two distinct Smad proteins from the fox-tapeworm Echinococcus multilocularis
    • Zavala-Gongora R., Kroner A., Wittek B., Knaus P., Brehm K. Identification and characterisation of two distinct Smad proteins from the fox-tapeworm Echinococcus multilocularis. International Journal for Parasitology 2003, 33:1665-1677.
    • (2003) International Journal for Parasitology , vol.33 , pp. 1665-1677
    • Zavala-Gongora, R.1    Kroner, A.2    Wittek, B.3    Knaus, P.4    Brehm, K.5
  • 44
    • 33644829445 scopus 로고    scopus 로고
    • A member of the transforming growth factor-beta receptor family from Echinococcus multilocularis is activated by human bone morphogenetic protein 2
    • Zavala-Gongora R., Kroner A., Bernthaler P., Knaus P., Brehm K. A member of the transforming growth factor-beta receptor family from Echinococcus multilocularis is activated by human bone morphogenetic protein 2. Molecular and Biochemical Parasitology 2006, 146:265-271.
    • (2006) Molecular and Biochemical Parasitology , vol.146 , pp. 265-271
    • Zavala-Gongora, R.1    Kroner, A.2    Bernthaler, P.3    Knaus, P.4    Brehm, K.5
  • 45
    • 37249021554 scopus 로고    scopus 로고
    • Molecular characterisation of a second structurally unusual AR-Smad without an MH1 domain and a Smad4 orthologue from Echinococcus multilocularis
    • Zavala-Gongora R., Derrer B., Gelmedin V., Knaus P., Brehm K. Molecular characterisation of a second structurally unusual AR-Smad without an MH1 domain and a Smad4 orthologue from Echinococcus multilocularis. International Journal for Parasitology 2008, 38:161-176.
    • (2008) International Journal for Parasitology , vol.38 , pp. 161-176
    • Zavala-Gongora, R.1    Derrer, B.2    Gelmedin, V.3    Knaus, P.4    Brehm, K.5


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