Efficacy of predictive modeling as a scientific criterion in dermal hazard identification for assignment of skin notations

Regulatory Toxicology and Pharmacology

Volumn 61, Issue 1, 2011, Pages 63-72

  Chen, Chen Peng ^a   Ahlers, Heinz W ^b   Scott Dotson, G ^b   Lin, Yi Chun ^a   Chang, Wei Chen ^a   Maier, Andrew ^c   Gadagbui, Bernard ^c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^c Toxicology Excellence for Risk Assessment   (United States)

Author keywords

Dermal lethal dose 50 ; Globally Harmonized System of Classification and Labeling of Chemicals; Hazard characterization; Hazard ranking; Occupational skin exposure; Octanol water partition coefficient; Predictive modeling; Skin notation

Indexed keywords

ACUTE TOXICITY; ARTICLE; CHEMICAL ACCIDENT; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; HAZARD ASSESSMENT; LD 50; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; OCCUPATIONAL HAZARD; OCCUPATIONAL SAFETY; OCCUPATIONAL TOXICOLOGY; PHYSICOCHEMICAL MODEL; PREDICTION; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SKIN ABSORPTION; SKIN NOTATION; SKIN TOXICITY; TOXIC INHALATION;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, INHALATION; ADMINISTRATION, TOPICAL; DERMIS; HAZARDOUS SUBSTANCES; HUMANS; LETHAL DOSE 50; LINEAR MODELS; MODELS, BIOLOGICAL; NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH (U.S.); OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; SKIN; SKIN DISEASES; UNITED STATES;

EID: 80052413568     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2011.05.013     Document Type: Article

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