In vitro dermal absorption rate testing of certain chemicals of interest to the Occupational Safety and Health Administration: Summary and evaluation of USEPA's mandated testing

Regulatory Toxicology and Pharmacology

Volumn 51, Issue 2, 2008, Pages 181-194

  Fasano, William J ^a   McDougal, James N ^b  

^a DUPONT COMPANY   (United States)

^b WRIGHT STATE UNIVERSITY   (United States)

Author keywords

Aqueous solutions; Flux; Human cadaver skin; In vitro dermal penetration and absorption; Industrial chemicals; Isopropyl myristate (IPM); Neat chemical; Permeability coefficient (Kp); Quantitative structure activity relationships (QSARs); Short term absorption rate; Skin notation; Steady state penetration; Structure activity relationships (SARs); Threshold limit values (TLVs); USEPA in vitro dermal test rule

Indexed keywords

INDUSTRIAL CHEMICAL; MYRISTIC ACID ISOPROPYL ESTER; WATER;

AQUEOUS SOLUTION; ARTICLE; CADAVER; CHEMICAL INDUSTRY; EXPOSURE VARIABLE; GOVERNMENT; HEALTH CARE MANAGEMENT; HUMAN; HUMAN TISSUE; IN VITRO STUDY; ISOTOPE LABELING; OCCUPATIONAL SAFETY; OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION; PERMEABILITY; PRIORITY JOURNAL; ROOM TEMPERATURE; SKIN ABSORPTION; SKIN DEFECT; STEADY STATE; STRUCTURE ACTIVITY RELATION; UNITED STATES;

HAZARDOUS SUBSTANCES; HUMANS; MODELS, BIOLOGICAL; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; PERMEABILITY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SKIN ABSORPTION; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

EID: 44649195620     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2008.04.005     Document Type: Article

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