Bax shuttling after neonatal hypoxia-ischemia: Hyperoxia effects

Journal of Neuroscience Research

Volumn 86, Issue 16, 2008, Pages 3584-3604

  Gill, Martin B ^a   Bockhorst, Kurt ^b   Narayana, Ponnada ^b   Perez Polo, J Regino ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Bax; Hyperoxia; Hypoxia ischemia; Inflammation; Necrosis

Indexed keywords

CALPAIN; CASPASE 12; CASPASE 3; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1BETA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN NECROSIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HYPEROXIA; INFLAMMATION; MITOCHONDRION; NEWBORN; NEWBORN HYPOXIA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BRAIN INFARCTION; CELL COMPARTMENTATION; CYTOPLASM; DISEASE MODELS, ANIMAL; HYPEROXIA; HYPOXIA-ISCHEMIA, BRAIN; INFLAMMATION MEDIATORS; NECROSIS; NERVE DEGENERATION; NEURONS; OXYGEN INHALATION THERAPY; PHENOTYPE; PROTEIN TRANSPORT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 59349101005     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21795     Document Type: Article

References (56)

1. Ashraf QM, Zanelli SA, Mishra OP, Ivoria-Papadopoulos M. 2001. Phosphorylation of Bcl-2 and Bax proteins during hypoxia in newborn piglets. Neurochem Res 26:1-9.
2. Bissinger RL, Ohning BL. 2006. Neonatal resuscitation. Available at: http://www.emedicine.com/ped/topic2598.htm Accessed 6 June 2008.
3. Blomgren K, Zhu C, Wang X, Karlsson JO, Leverin AL, Bahr BA, Mallard C, Hagberg H. 2001. Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"? J Biol Chem 276:10191-10198.
4. Bochning D, Patterson RL, Sedaghat L, Glebova NO, Kurosaki T, Snyder SH. 2003. Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat Cell Biol 5:1051-1061.
5. Brooks TF, Humphreys WM. 2004. A deconvolution approach for the mapping of acoustic sources (DAMAS) determined from phased microphone arrays. American Institute of Aeronautics and Astronautics 2954. p 1-18.
6. Cittelly DM, Nesic-Taylor O, Perez-Polo JR. 2007. Phosphorylation of Bcl-x(L) after spinal cord injury. J Neurosci Res 85:1894-1911.
7. Clarkson AN, Clarkson J, Jackson DM, Sammut IA. 2007. Mitochondrial involvement in transhemispheric diaschisis following hypoxia-ischemia: clomethiazole-mediated amelioration. Neuroscience. 144:547-561.
8. 2 injury. J. Neurochemistry 82:19-29.
9. Cole K, Perez-Polo JR. 2004. Neuronal trauma model: in search of Thanatos. Int J Dev Neurosci 22:485-496.
10. Culmsee C, Zhu C, Landshamer S, Becattini B, Wagner E, Pellecchia M, Blomgren K, Plesnila N. 2005. Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia. J Neurosci 25:10262-10272.
11. de Menezes MS, Shaw DW. 2006. Hypoxic-ischemic brain injury in the newborn. Available at: http://www.emedicine.com/neuro/topic696.htm. Accessed June 6, 2008.
12. Ditsworth D, Zong WX, Thompson CB. 2007. Activation of poly (ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus. J Biol Chem 282:17845-17854.
13. Dougherty RP. 2005. Extensions of DAMAS and benefits and limitations of deconvolution in beamforming. American Institute of Aeronautics and Astronautics 2961. p 1-18.
14. Edinger AL, Thompson CB. 2004. Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 16:663-669.
15. Englander EW, Greeley GH Jr, Wanger G Jr, Perez-Polo JR, Lee HM. 1999. Hypoxia-induced mitochondrial and nuclear DNA damage in the rat brain. J Neurosci Res 58:262-269.
16. Fabian RH, Perez-Polo JR, Kent TA. 2007. A decoy oligonucleotide inhibiting NF-κB binding to the IgGκB consensus site reduces cerebral injury and apoptosis in neonatal hypoxic-ischemic encephalopathy. J Neurosci Res 85:1420-1426.
17. Fatemi SH, Pearce DA, Brooks AI, Sidwell RW. 2005. Prenatal viral infection in mouse causes differential expression of genes in brains of mouse progeny: a potential animal model for schizophrenia and autism. Synapse 57:91-99.
18. Gajkowska B, Wojewodzka U, Gajda J. 2004. Translocation of Bax and Bid to mitochondria, endoplasmic reticulum and nuclear envelope: possible control points in apoptosis. J Mol Histol 35:11-19.
19. Gill MB, Perez-Polo JR. 2008. Hypoxia ischemia-mediated cell death in neonatal rat brain. Neurochem Res [Epub ahead of print].
20. Gobeil S, Boucher CC, Nadeau D, Poirier GG. 2001. Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases. Cell Death Differ 8:588-594.
21. Godlewski MM, Motyl MA, Gajkowska B, Wareski P, Koronkiewicz M, Motyl T. 2001. Subcellular redistribution of BAX during apoptosis induced by anticancer drugs. Anticancer Drugs 12:607-617.
22. Grafe MR, Woodworth KN, Noppens K, Perez-Polo JR. 2008. Long-term histological outcome after post-hypoxic treatment with 100% or 40% oxygen in a model of perinatal hypoxic-ischemic brain injury. Int J Dev Neurosci 26:119-124.
23. 2+ oscillation. J Biochem Mol Biol 38:709-716.
24. Hu X, Qiu J, Grafe MR, Rea HC, Rassin DK, Perez-Polo JR. 2003. Bcl-2 family members make different contributions to cell death in hypoxia and/ or hyperoxia in rat cerebral cortex. Int J Dev Neurosci 21:371-378.
25. Hu X, Nesic-Tavlor O, Qiu J, Rea HC, Fabian R, Rassin DK, Perez-Polo JR. 2005b. Activation of nuclear factor-κB signaling pathway by interleukin-1 after hypoxia/ischemia in neonatal rat hippocampus and cortex. J Neurochem 93:26-37.
26. Hu X, Rea HC, Wiktorowicz JE, Percz-Polo JR. 2006. Proteomic analysis of hypoxia/ischemia-induced alteration of cortical development and dopamine neurotransmission in neonatal rat. J Protcome Res 5:2396-2404.
27. Kalai M, Lamkanfi M, Denecker G, Boogmans M, Lippens S, Meeus A, Declercq W, Vandenabeele P. 2003. Regulation of the expression and processing of caspase-12. J Cell Biol 162:457-467.
28. Karlsson J, Pietras A, Beckman S, Pettersson HM, Larsson C, Pahlman S. 2007. Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax. Oncogene 13:6150-6159.
29. Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH. 2006a. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nat Cell Biol 8:1348-1358.
30. Kim JB, Sig CJ, Yu YM, Nam K, Piao CS, Kim SW, Lee MH, Han PL, Park JS, Lee JK. 2006b. HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain. J Neurosci 26:6413-6421.
31. Korsmeyer SJ, Gross A, Harada H, Zha J, Wang K, Yin XM, Wei M, Zinkel S. 1999. Death and survival signals determine active/inactive conformations of pro-apoptotic BAX, BAD, and BID molecules. Cold Spring Harb Symp Quant Biol 64:343-350.
32. Larner SF, Hayes RL, Wang KK. 2006. Unfolded protein response after neurotrauma. J Neurotrauma 23:807-829.
33. 4. Int J Dev Neurosci 26:77-85.
34. Martin SS, Perez-Polo JR, Noppens KM, Grafe MR. 2005. Biphasic changes in the levels of poly(ADP-ribose) polymerase-1 and caspase 3 in the immature grain following hypoxia-ischemia. Int J Dev Neurosci 23:673-686.
35. Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissierde MJ, Susin SA. 2007. Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol Cell Biol 27:4844-4862.
36. Nakajima W, Ishida A, Lange MS, Gabrielson KL, Wilson MA, Martin LJ, Blue ME, Johnston MV. 2000. Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat. J Neurosci 20:7994-8004.
37. Noda T, Farquhar MG. 1992. A non-autophagic pathway for diversion of ER secretory proteins to lysosomes. J Cell Biol 119:85-97.
38. Oakes SA, Scorrano L, Opferman JT, Bassik MC, Nishino M, Pozzan T, Korsmeyer SJ. 2005. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proc Natl Acad Sci U S A 102:105-110.
39. Odding E, Roebroeck ME, Stam HJ. 2006. The epidemiology of cerebral palsy: incidence, impairments and risk factors. Disabil Rehabil 28:183-191.
40. Pal R, Mandal A, Ran HS, Rao MS, Khanna A. 2007. A panel of tests to standardize the characterization of human embryonic stem cells. Regen Med 2:179-192.
41. Palkovits M, Brownstein MJ. 1988. Maps and guide to microdissection of the rat brain. New York: Elsevier. p 128.
42. Platt MJ, Cans C, Johnson A, Surman G, Topp M, Torrioli MG, Krageloh-Mann I. 2007. Trends in cerebral palsy among infants of very low birthweight (<1500 g) or born prematurely (<32 weeks) in 16 European centres: a database study. Lancet 369:43-50.
43. Polster BM, Basanez G, Etxebarria A, Hardwick JM, Nicholls DG. 2005. Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J Biol Chem 280:6447-6454.
44. Qiu J, Hu X, Nesic O, Grafe MR, Rassin DK, Perez-Polo JR. 2004. Effects of NF-κB oligonucleotide "decoys" on gene expression in p7 rat hippocampus after hypoxia/ischemia. J Neursci Res 77:108-118.
45. Raffo AJ, Kim AL, Fine RL. 2000. Formation of nuclear Bax/p53 complexes is associated with chemotreatment induced apoptosis. Oncogene 19:6216-6228.
46. Reed JC. 2006. Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities. Cell Death Differ 13:1378-1386.
47. Salah-Eldin A, Inoue S, Tsuda M, Matsuura A. 2000. Abnormal intracellular localization of Bax with a normal membrane anchor domain in human lung cancer cell lines. Jpn J Cancer Res 91:1269-1277.
48. Sanges D, Comitato A, Tammaro R, Marigo V. 2006. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci U S A 103:17366-17371.
49. She QB, Chen N, Deng Z. 2000. ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation. J Biol Chem 275:20444-20449.
50. Smith KE, Keeney S, Zhang L, Perez-Polo R, Rassing DK. 2008. The association of early blood oxygenation with child development in preterm infants with acute respiratory disorders. Int J Dev Neurosci 26:125-131
51. Vannucci RC, Lyons DT, Vasta F. 1988. Regional cerebral blood flow during hypoxia-ischemia in immature rats. Stroke 19:245-250.
52. Walton M, Connor B, Lawlor P, Young D, Sirimanne E, Gluckman P, Cole G, Dragunow M. 1999. Neuronal death and survival in two models of hypoxic-ischemic brain damage. Brain Res Brain Res Rev 29:137-168.
53. Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ. 2001. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292:727-730.
54. Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG, Youle RJ. 1997. Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol 139:1281-1292.
55. Zhu C, Wang X, Hagberg H, Blomgren K. 2000. Correlation between caspase-3 activation and three different markers of DNA damage in neonatal cerebral hypoxia-ischemia. J Neurochem 75:819-829.
56. Zhu C, Wang X, Huang Z, Qiu L, Xu F, Vahsen N, Nilsson M, Eriksson PS, Hagberg H, Culmsee C, Plesnila N, Kroemer G, Blomgren K. 2007. Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia. Cell Death Differ 14:775-784.