Saccadic inhibition reveals the timing of automatic and voluntary signals in the human brain

Journal of Neuroscience

Volumn 31, Issue 35, 2011, Pages 12501-12512

  Bompas, Aline ^a   Sumner, Petroc ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BEHAVIOR; BRAIN FUNCTION; CONTROLLED STUDY; EYE MOVEMENT CONTROL; FACILITATION; FEMALE; HUMAN; HUMAN EXPERIMENT; LATENT PERIOD; MALE; MATHEMATICAL MODEL; NEUROPHYSIOLOGY; NORMAL HUMAN; PREDICTION; PRIORITY JOURNAL; RETINOTECTAL PROJECTION; SACCADIC EYE MOVEMENT; SACCADIC INHIBITION; SIGNAL TRANSDUCTION; THEORETICAL MODEL; VISUAL STIMULATION;

BRAIN; EVOKED POTENTIALS, VISUAL; FEMALE; HUMANS; INHIBITION (PSYCHOLOGY); MALE; MODELS, NEUROLOGICAL; PHOTIC STIMULATION; REACTION TIME; SACCADES; VISUAL FIELDS; VISUAL PERCEPTION;

EID: 80052383703     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2234-11.2011     Document Type: Article

References (62)

1. Anderson AJ, Carpenter RH (2008) The effect of stimuli that isolate S-cones on early saccades and the gap effect. Proc R Soc Lond B Biol Sci 275:335-344.
2. Antoniades CA, Altham PM, Mason SL, Barker RA, Carpenter R (2007) Saccadometry: a new tool for evaluating presymptomatic Huntington patients. Neuroreport 18:1133-1136.
3. Bichot NP, Schall JD (2002) Priming in macaque frontal cortex during popout visual search: feature-based facilitation and location-based inhibition of return. J Neurosci 22:4675-4685.
4. Bompas A, Sumner P (2008) Sensory sluggishness dissociates saccadic, manual, and perceptual responses: an S-cone study. J Vis 8:1-13.
5. Bompas A, Sumner P (2009a) Oculomotor distraction by signals invisible to the retinotectal and magnocellular pathways. J Neurophysiol 102:2387-2395.
6. Bompas A, Sumner P (2009b) Temporal dynamics of saccadic distraction. J Vis 9:1-14.
7. Bompas A, Sterling T, Rafal RD, Sumner P (2008) Naso-temporal asymmetry for signals invisible to the retinotectal pathway. J Neurophysiol 100:412-421.
8. Boot WR, Kramer AF, Peterson MS (2005) Oculomotor consequences of abrupt object onsets and offsets: onsets dominate oculomotor capture. Percept Psychophys 67:910-928.
9. Boucher L, Palmeri TJ, Logan GD, Schall JD (2007) Inhibitory control in mind and brain: an interactive race model of countermanding saccades. Psychol Rev 114:376-397.
10. Brown S, Heathcote A (2005) A ballistic model of choice response time. Psychol Rev 112:117-128.
11. Brown SD, Heathcote A (2008) The simplest complete model of choice response time: linear ballistic accumulation. Cogn Psychol 57:153-178.
12. Buonocore A, McIntosh RD (2008) Saccadic inhibition underlies the remote distractor effect. Exp Brain Res 191:117-122.
13. Carpenter RHS (1994) SPIC: a PC-based system for rapid measurement of saccadic responses. J Physiol 480:4P.
14. Carpenter RH, Williams ML (1995) Neural computation of log likelihood in control of saccadic eye-movements. Nature 377:59-62.
15. Carpenter RH, Reddi BA, Anderson AJ (2009) A simple two-stage model predicts response time distributions. J Physiol 587:4051-4062.
16. Cutsuridis V, Smyrnis N, Evdokimidis I, Perantonis S (2007) A neural model of decision-making by the superior colicullus in an antisaccade task. Neural Netw 20:690-704.
17. DeSouza JF, Menon RS, Everling S (2003) Preparatory set associated with pro-saccades and anti-saccades in humans investigated with event-related FMRI. J Neurophysiol 89:1016-1023.
18. Dorris MC, Olivier E, Munoz DP (2007) Competitive integration of visual and preparatory signals in the superior colliculus during saccadic programming. J Neurosci 27:5053-5062.
19. Edelman JA, Xu KZ (2009) Inhibition of voluntary saccadic eye movement commands by abrupt visual onsets. J Neurophysiol 101:1222-1234.
20. Everling S, Munoz DP (2000) Neuronal correlates for preparatory set associated with pro-saccades and anti-saccades in the primate frontal eye field. J Neurosci 20:387-400.
21. Everling S, Tinsley CJ, Gaffan D, Duncan J (2006) Selective representation of task-relevant objects and locations in the monkey prefrontal cortex. Eur J Neurosci 23:2197-2214.
22. Glimcher PW (2001) Making choices: the neurophysiology of visualsaccadic decision making. Trends Neurosci 24:654-659.
23. Godijn R, Theeuwes J (2002) Programming of endogenous and exogenous saccades: evidence for a competitive integration model. J Exp Psychol Hum Percept Perform 28:1039-1054.
24. Hanes DP, Schall JD (1996) Neural control of voluntary movement initiation. Science 274:427-430.
25. Hermens F, Walker W (2010) The influence of onsets and offsets on saccade programming. i-Perception 1:83-94.
26. Kopecz K (1995) Saccadic reaction times in gap/overlap paradigms: a model based on integration of intentional and visual information on neural, dynamic fields. Vision Res 35:2911-2925.
27. Leigh RJ, Kennard C (2004) Using saccades as a research tool in the clinical neurosciences. Brain 127:460-477.
28. Lo CC, Boucher L, Paré M, Schall JD, Wang XJ (2009) Proactive inhibitory control and attractor dynamics in countermanding action: a spiking neural circuit model. J Neurosci 29:9059-9071.
29. Logan GD, Cowan WB (1984) On the ability to inhibit thought and action: a theory of an act of control. Psychol Rev 91:295-327.
30. Ludwig CJ, Mildinhall JW, Gilchrist ID (2007) Apopulation coding account for systematic variation in saccadic dead time. J Neurophysiol 97:795-805.
31. Ludwig CJ, Butler SH, Rossit S, Harvey M, Gilchrist ID (2009) Modelling contralesional movement slowing after unilateral brain damage. Neurosci Lett 452:1-4.
32. Meeter M, Van der Stigchel S, Theeuwes J (2010) A competitive integration model of exogenous and endogenous eye movements. Biol Cybern 102:271-291.
33. Munoz DP, Everling S (2004) Look away: the anti-saccade task and the voluntary control of eye movement. Nat Rev Neurosci 5:218-228.
34. Munoz DP, Wurtz RH (1993) Fixation cells in monkey superior colliculus. II. Reversible activation and deactivation. J Neurophysiol 70:576-589.
35. Ottes FP, Van Gisbergen JA, Eggermont JJ (1986) Visuomotor fields of the superior colliculus: a quantitative model. Vision Res 26:857-873.
36. Posner MI, Cohen Y (1980) Attention and the control of movements. In: Tutorials in motor behaviour (Stelmach GE, Requin J, eds), pp 243-258. Amsterdam: North Holland.
37. Rafal R, Smith J, Krantz J, Cohen A, Brennan C (1990) Extrageniculate vision in hemianopic humans: saccade inhibition by signals in the blind field. Science 250:118-121.
38. Ratcliff R, Cherian A, Segraves M (2003) A comparison of macaque behavior and superior colliculus neuronal activity to predictions from models of two-choice decisions. J Neurophysiol 90:1392-1407.
39. Reingold EM, Stampe DM (1999) Saccadic inhibition in complex visual tasks. In: Current oculomotor research: physiological and psychological aspects (Becker W, Deubel H, Mergner T, eds), pp 249-255. New York: Plenum.
40. Reingold EM, Stampe DM (2000) Saccadic inhibition and gaze contingent research paradigms. In: Reading as a perceptual process (Kennedy A, Radach R, Heller D, Pynte J, eds), pp 119-145. Amsterdam: Elsevier.
41. Reingold EM, Stampe DM (2002) Saccadic inhibition in voluntary and reflexive saccades. J Cogn Neurosci 14:371-388.
42. Reingold EM, Stampe DM (2003) Using the saccadic inhibition paradigm to investigate saccadic control in reading. In: Mind's eye: cognitive and applied aspects of eye movement research (Radach R, Hyona J, Deubel H, eds), pp 347-360. Amsterdam: Elsevier Science.
43. Reingold EM, Stampe DM (2004) Saccadic inhibition in reading. J Exp Psychol Human 30:194-211.
44. Satel J, Wang Z, Trappenberg TP, Klein RM (2011) Modeling inhibition of return as short-term depression of early sensory input to the superior colliculus. Vision Res 51:987-996.
45. Schall JD (2004) On building a bridge between brain and behavior. Annu Rev Psychol 55:23-50.
46. Shadlen MN, Britten KH, Newsome WT, Movshon JA (1996) A computational analysis of the relationship between neuronal and behavioral responses to visual motion. J Neurosci 16:1486-1510.
47. Smit AC, Van Gisbergen JA (1989) A short-latency transition in saccade dynamics during square-wave tracking and its significance for the differentiation of visually-guided and predictive saccades. Exp Brain Res 76:64-74.
48. Smith PL, Ratcliff R (2004) Psychology and neurobiology of simple decisions. Trends Neurosci 27:161-168.
49. Smithson HE, Sumner P, Mollon JD (2003) How to find a tritan line. In: Normal and defective colour vision (Mollon JD, Pokorny J, Knoblauch K, eds), pp 279-287. Oxford: Oxford UP.
50. Smyrnis N, Karantinos T, Malogiannis I, Theleritis C, Mantas A, Stefanis NC, Hatzimanolis J, Evdokimidis I (2009) Larger variability of saccadic reaction times in schizophrenia patients. Psychiatry Res 168: 129-136.
51. Sumner P, Adamjee T, Mollon JD (2002) Signals invisible to the collicular and magnocellular pathways can capture visual attention. Curr Biol 12:1312-1316.
52. Sumner P, Nachev P, Castor-Perry S, Isenman H, Kennard C (2006) Which visual pathways cause fixation-related inhibition? J Neurophysiol 95:1527-1536.
53. Temel Y, Visser-Vandewalle V, Carpenter RH (2009) Saccadometry: a novel clinical tool for quantification of the motor effects of subthalamic nucleus stimulation in Parkinson's disease. Exp Neurol 216:481-489.
54. Trappenberg TP, Dorris MC, Munoz DP, Klein RM (2001) A model of saccade initiation based on the competitive integration of exogenous and endogenous signals in the superior colliculus. J Cogn Neurosci 13: 256-271.
55. Usher M, McClelland JL (2001) The time course of perceptual choice: the leaky, competing accumulator model. Psychol Rev 108:550-592.
56. Walker R, Deubel H, Schneider WX, Findlay JM (1997) Effect of remote distractors on saccade programming: evidence for an extended fixation zone. J Neurophysiol 78:1108-1119.
57. Weiskrantz L (1986) Blindsight: a case study and implications. Oxford: Oxford UP.
58. White BJ, Munoz DP (2011) Separate visual signals for saccade initiation during target selection in the primate superior colliculus. J Neurosci 31:1570-1578.
59. White BJ, Boehnke SE, Marino RA, Itti L, Munoz DP (2009) Color-related signals in the primate superior colliculus. J Neurosci 29:12159-12166.
60. Wilimzig C, Schneider S, Schöner G (2006) The time course of saccadic decision making: dynamic field theory. Neural Netw 19:1059-1074.
61. Wong-Lin K, Eckhoff P, Holmes P, Cohen JD (2010) Optimal performance in a countermanding saccade task. Brain Res 1318:178-187.
62. Yoshida M, Takaura K, Kato R, Ikeda T, Isa T (2008) Striate cortical lesions affect deliberate decision and control of saccade: implication for blindsight. J Neurosci 28:10517-10530.