Neuronal tryptophan hydroxylase expression in BALB/cJ and C57Bl/6J mice

Journal of Neurochemistry

Volumn 118, Issue 6, 2011, Pages 1067-1074

  Bach, Helene ^a,b   Arango, Victoria ^b   Huang, Yung Yu ^a,b   Leong, Sharlene ^a   John Mann, J ^a,b   Underwood, Mark D ^a,b  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

5 HT; depression; dorsal raphe nucleus; immunocytochemistry; Tph2

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; MESSENGER RNA; SEROTONIN; TRYPTOPHAN HYDROXYLASE;

ANIMAL BEHAVIOR; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; BRAIN CORTEX; BRAIN NERVE CELL; BRAIN STEM; C57BL 6 MOUSE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; GENE; GENETIC TRANSCRIPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MESENCEPHALON; MOUSE; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRAIN DIFFERENCE; TPH2 GENE;

ANIMALS; AUTORADIOGRAPHY; BRAIN CHEMISTRY; CELL COUNT; DENSITOMETRY; HYDROXYINDOLEACETIC ACID; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEURONS; RAPHE NUCLEI; SEROTONIN; SPECIES SPECIFICITY; TRYPTOPHAN HYDROXYLASE;

MUS;

EID: 80052357619     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07379.x     Document Type: Article

References (37)

1. Abumaria N., Rygula R., Hiemke C., Fuchs E., Havemann-Reinecke U., Ruther E., and, Flugge G., (2007) Effect of chronic citalopram on serotonin-related and stress-regulated genes in the dorsal raphe nucleus of the rat. Eur. Neuropsychopharmacol. 17, 417-429. (Pubitemid 46497654)
2. Arango V., Underwood M. D., Boldrini M., Tamir H., Kassir S. A., Hsiung S., Chen J. J. X., and, Mann J. J., (2001) Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims. Neuropsychopharmacology 25, 892-903. (Pubitemid 34031894)
3. Bach-Mizrachi H., Underwood M. D., Kassir S. A., Bakalian M. J., Sibille E., Tamir H., Mann J. J., and, Arango V., (2006) Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide. Neuropsychopharmacology 31, 814-824.
4. Bach-Mizrachi H., Underwood M. D., Tin A., Ellis S. P., Mann J. J., and, Arango V., (2008) Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides. Mol. Psychiatry 13, 507-513. (Pubitemid 351556034)
5. Beaulieu J. M., Zhang X., Rodriguiz R. M., Sotnikova T. D., Cools M. J., Wetsel W. C., Gainetdinov R. R., and, Caron M. G., (2008) Role of GSK3beta in behavioral abnormalities induced by serotonin deficiency. Proc. Natl Acad. Sci. US A 105, 1333-1338. (Pubitemid 351397053)
6. Bethea C. L., Centeno M. L., and, Cameron J. L., (2008) Neurobiology of stress-induced reproductive dysfunction in female macaques. Mol. Neurobiol. 38, 199-230.
7. Bhansali P., Dunning J., Singer S. E., David L., and, Schmauss C., (2007) Early life stress alters adult serotonin 2C receptor pre-mRNA editing and expression of the alpha subunit of the heterotrimeric G-protein G q. J. Neurosci. 27, 1467-1473.
8. Boldrini M., Underwood M. D., Mann J. J., and, Arango V., (2005) More tryptophan hydroxylase in the brainstem dorsal raphe nucleus in depressed suicides. Brain Res. 1041, 19-28. (Pubitemid 40445385)
9. Bonkale W. L., Murdock S., Janosky J. E., and, Austin M. C., (2004) Normal levels of tryptophan hydroxylase immunoreactivity in the dorsal raphe of depressed suicide victims. J. Neurochem. 88, 958-964. (Pubitemid 38199317)
10. Briones-Aranda A., Rocha L., and, Picazo O., (2005) Influence of forced swimming stress on 5-HT1A receptors and serotonin levels in mouse brain. Prog. Neuropsychopharmacol. Biol. Psychiatry 29, 275-281. (Pubitemid 40202914)
11. Brodal A., Taber E., and, Walberg F., (1960) The raphe nuclei of the brain stem of the cat: efferent projections. J. Comp. Neurol. 114, 239-259.
12. Browne C. A., Clarke G., Dinan T. G., and, Cryan J. F., (2011) Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains. Neuropharmacology 60, 683-691.
13. Cervo L., Canetta A., Calcagno E., Burbassi S., Sacchetti G., Caccia S., Fracasso C., Albani D., Forloni G., and, Invernizzi R. W., (2005) Genotype-dependent activity of tryptophan hydroxylase-2 determines the response to citalopram in a mouse model of depression. J. Neurosci. 25, 8165-8172. (Pubitemid 41292111)
14. Chamas F. M., Underwood M. D., Arango V., Serova L., Kassir S. A., Mann J. J., and, Sabban E. L., (2004) Immobilization stress elevates tryptophan hydroxylase mRNA and protein in the rat raphe nuclei. Biol. Psychiatry 55, 278-283. (Pubitemid 38117164)
15. Crawley J. N., Belknap J. K., Collins A., et al. (1997) Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology (Berl) 132, 107-124. (Pubitemid 27338986)
16. Dulawa S. C., Holick K. A., Gundersen B., and, Hen R., (2004) Effects of chronic fluoxetine in animal models of anxiety and depression. Neuropsychopharmacology 29, 1321-1330. (Pubitemid 38780655)
17. Franklin K. B. J., and, Paxinos G., (1997) The Mouse Brain in Stereotaxic Coordinates. Academic Press, San Diego.
18. Goswami D. B., May W. L., Stockmeier C. A., and, Austin M. C., (2010) Transcriptional expression of serotonergic regulators in laser-captured microdissected dorsal raphe neurons of subjects with major depressive disorder: sex-specific differences. J. Neurochem. 112, 397-409.
19. Holick K. A., Lee D. C., Hen R., and, Dulawa S. C., (2007) Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor. Neuropsychopharmacology 33, 406-417.
20. Hornung J. P., (2003) The human raphe nuclei and the serotonergic system. J. Chem. Neuroanat. 26, 331-343.
21. Lima F. B., Centeno M. L., Costa M. E., Reddy A. P., Cameron J. L., and, Bethea C. L., (2009) Stress sensitive female macaques have decreased fifth Ewing variant (Fev) and serotonin-related gene expression that is not reversed by citalopram. Neuroscience 164, 676-691.
22. Lira A., Zhou M., Castanon N., et al. (2003) Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biol. Psychiatry 54, 960-971. (Pubitemid 37415032)
23. Lucki I., Dalvi A., and, Mayorga A. J., (2001) Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice. Psychopharmacology (Berl) 155, 315-322. (Pubitemid 32477289)
24. Mann J. J., Bortinger J., Oquendo M. A., Currier D., Li S., and, Brent D. A., (2005) Family history of suicidal behavior and mood disorders in probands with mood disorders. Am. J. Psychiatry 162, 1672-1679. (Pubitemid 41318237)
25. Mann J. J., Currier D., Stanley B., Oquendo M. A., Amsel L. V., and, Ellis S. P., (2006) Can biological tests assist prediction of suicide in mood disorders? Int. J. Neuropsychopharmacol. 9, 465-474. (Pubitemid 43979707)
26. 14C-plastic standards for quantitative autoradiography using LKB Ultrofilm or Amersham Hyperfilm. Neurosci. Lett. 121, 211-214.
27. Nakamura K., Sugawara Y., Sawabe K., et al. (2006) Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels. J. Neurosci. 26, 530-534. (Pubitemid 43237117)
28. Osipova D. V., Kulikov A. V., and, Popova N. K., (2009) C1473G polymorphism in mouse tph2 gene is linked to tryptophan hydroxylase-2 activity in the brain, intermale aggression, and depressive-like behavior in the forced swim test. J. Neurosci. Res. 87, 1168-1174.
29. Pierce E. T., Foote W. E., and, Hobson J. A., (1976) The efferent connection of the nucleus raphe dorsalis. Brain Res. 107, 137-144.
30. Siesser W. B., Zhang X., Jacobsen J. P., Sotnikova T. D., Gainetdinov R. R., and, Caron M. G., (2010) Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice. Neurosci. Lett. 481, 6-11.
31. Träskman L., Ãsberg M., Bertilsson L., and, Sjöstrand L., (1981) Monoamine metabolites in CSF and suicidal behavior. Arch. Gen. Psychiatry 38, 631-636. (Pubitemid 11064819)
32. Underwood M. D., Khaibulina A. A., Ellis S. P., Moran A., Rice P. M., Mann J. J., and, Arango V., (1999) Morphometry of the dorsal raphe nucleus serotonergic neurons in suicide victims. Biol. Psychiatry 46, 473-483. (Pubitemid 29369073)
33. Underwood M. D., Landau A. P., Liu Y., Kassir S. A., Francis J. H., Lisanby S. H., Fairbanks L. A., Bakalian M. J., Mann J. J., and, Arango V., (2003) Comparative neuroanatomy of the serotonergic dorsal raphe nucleus in rodents, monkeys, and humans. Program No. 94.15 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2003.
34. Winge I., McKinney J. A., Knappskog P. M., and, Haavik J., (2007) Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2. J. Neurochem. 100, 1648-1657. (Pubitemid 46376200)
35. Winge I., McKinney J. A., Ying M., D'Santos C. S., Kleppe R., Knappskog P. M., and, Haavik J., (2008) Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding. Biochem. J. 410, 195-204. (Pubitemid 351300339)
36. Zhang X., Beaulieu J. M., Sotnikova T. D., Gainetdinov R. R., and, Caron M. G., (2004) Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science 305, 217. (Pubitemid 38886729)
37. Zhang X., Gainetdinov R. R., Beaulieu J. M., Sotnikova T. D., Burch L. H., Williams R. B., Schwartz D. A., Krishnan K. R., and, Caron M. G., (2005) Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16. (Pubitemid 40075345)