메뉴 건너뛰기




Volumn 19, Issue 3, 2011, Pages 142-150

Involvement of subtypes γ and ε of protein kinase C in colon pain induced by formalin injection

Author keywords

Colon; Formalin; Protein kinase C; Visceral pain; Wide dynamic range neuron

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; FORMALDEHYDE; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C EPSILON; PROTEIN KINASE C GAMMA;

EID: 80052344191     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000328311     Document Type: Article
Times cited : (15)

References (55)
  • 1
    • 0030881680 scopus 로고    scopus 로고
    • Preserved acute pain and reduced neuropathic pain in mice lacking PKCγ
    • DOI 10.1126/science.278.5336.279
    • Malmberg AB, Chen C, Tonegawa S, Basbaum AI: Preserved acute pain and reduced neuropathic pain in mice lacking PKC-gamma. Science 1997; 278: 279-283. (Pubitemid 27450873)
    • (1997) Science , vol.278 , Issue.5336 , pp. 279-283
    • Malmberg, A.B.1    Chen, C.2    Tonegawa, S.3    Basbaum, A.I.4
  • 2
    • 0034589725 scopus 로고    scopus 로고
    • Protein kinase subtypes involved in injury-induced nociception
    • DOI 10.1016/S0079-6123(00)29005-5
    • Malmberg AB: Protein kinase subtypes involved in injury-induced nociception. Prog Brain Res 2000; 129: 51-59. (Pubitemid 35461185)
    • (2000) Progress in Brain Research , vol.129 , pp. 51-59
    • Malmberg, A.B.1
  • 3
    • 0026713777 scopus 로고
    • Painrelated increases in spinal cord membranebound protein kinase C following peripheral nerve injury
    • Mao J, Price DD, Mayer DJ, Hayes RL: Painrelated increases in spinal cord membranebound protein kinase C following peripheral nerve injury. Brain Res 1992; 588: 144-149.
    • (1992) Brain Res , vol.588 , pp. 144-149
    • Mao, J.1    Price, D.D.2    Mayer, D.J.3    Hayes, R.L.4
  • 5
    • 77952289342 scopus 로고    scopus 로고
    • Involvement of the spinal NMDA receptor/PKC-gamma signaling pathway in the development of bone cancer pain
    • Xiaoping G, Xiaofang Z, Yaguo Z, Juan Z, Junhua W, Zhengliang M: Involvement of the spinal NMDA receptor/PKC-gamma signaling pathway in the development of bone cancer pain. Brain Res 2010; 1335: 83-90.
    • (2010) Brain Res , vol.1335 , pp. 83-90
    • Xiaoping, G.1    Xiaofang, Z.2    Yaguo, Z.3    Juan, Z.4    Junhua, W.5    Zhengliang, M.6
  • 6
    • 77649339670 scopus 로고    scopus 로고
    • The effects of sympathetic outflow on upregulation of vanilloid receptors TRPV(1) in primary afferent neurons evoked by intradermal capsaicin
    • Xu X, Wang P, Zou X, Li D, Fang L, Gong K, Lin Q: The effects of sympathetic outflow on upregulation of vanilloid receptors TRPV(1) in primary afferent neurons evoked by intradermal capsaicin. Exp Neurol 2010; 222: 93-107.
    • (2010) Exp Neurol , vol.222 , pp. 93-107
    • Xu, X.1    Wang, P.2    Zou, X.3    Li, D.4    Fang, L.5    Gong, K.6    Lin, Q.7
  • 7
    • 0034808388 scopus 로고    scopus 로고
    • Differential effects of NMDA and group I mGluR antagonists on both nociception and spinal cord protein kinase C translocation in the formalin test and a model of neuropathic pain in rats
    • DOI 10.1016/S0304-3959(01)00337-2, PII S0304395901003372
    • Yashpal K, Fisher K, Chabot JG, Coderre TJ: Differential effects of NMDA and group I mGluR antagonists on both nociception and spinal cord protein kinase C translocation in the formalin test and a model of neuropathic pain in rats. Pain 2001; 94: 17-29. (Pubitemid 32907554)
    • (2001) Pain , vol.94 , Issue.1 , pp. 17-29
    • Yashpal, K.1    Fisher, K.2    Chabot, J.-G.3    Coderre, T.J.4
  • 8
    • 0032104245 scopus 로고    scopus 로고
    • The extended protein kinase C superfamily
    • Mellor H, Parker PJ: The extended protein kinase C superfamily. Biochem J 1998; 332: 281-292. (Pubitemid 28271856)
    • (1998) Biochemical Journal , vol.332 , Issue.2 , pp. 281-292
    • Mellor, H.1    Parker, P.J.2
  • 9
    • 2342642103 scopus 로고    scopus 로고
    • Synaptic plasticity in the amygdala in a visceral pain model in rats
    • DOI 10.1016/j.neulet.2003.12.027, PII S0304394003014113
    • Han JS, Neugebauer V: Synaptic plasticity in the amygdala in a visceral pain model in rats. Neurosci Lett 2004; 361: 254-257. (Pubitemid 38609264)
    • (2004) Neuroscience Letters , vol.361 , Issue.1-3 , pp. 254-257
    • Han, J.S.1    Neugebauer, V.2
  • 10
    • 0035370250 scopus 로고    scopus 로고
    • A new model of visceral pain and referred hyperalgesia in the mouse
    • DOI 10.1016/S0304-3959(01)00275-5, PII S0304395901002755
    • Laird JM, Martinez-Caro L, Garcia-Nicas E, Cervero F: A new model of visceral pain and referred hyperalgesia in the mouse. Pain 2001; 92: 335-342. (Pubitemid 32480163)
    • (2001) Pain , vol.92 , Issue.3 , pp. 335-342
    • Laird, J.M.A.1    Martinez-Caro, L.2    Garcia-Nicas, E.3    Cervero, F.4
  • 11
    • 28844497653 scopus 로고    scopus 로고
    • Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon
    • DOI 10.1053/j.gastro.2005.09.013, PII S001650850501797X
    • Qin C, Malykhina AP, Akbarali HI, Foreman RD: Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon. Gastroenterology 2005; 129: 1967-1978. (Pubitemid 41772974)
    • (2005) Gastroenterology , vol.129 , Issue.6 , pp. 1967-1978
    • Qin, C.1    Malykhina, A.P.2    Akbarali, H.I.3    Foreman, R.D.4
  • 12
    • 0028246219 scopus 로고
    • Inflammation of the colonic wall induced by formalin as a model of acute visceral pain
    • DOI 10.1016/0304-3959(94)90008-6
    • Miampamba M, Chery-Croze S, Gorry F, Berger F, Chayvialle JA: Inflammation of the colonic wall induced by formalin as a model of acute visceral pain. Pain 1994; 57: 327-334. (Pubitemid 24197333)
    • (1994) Pain , vol.57 , Issue.3 , pp. 327-334
    • Miampamba, M.1    Chery-Croze, S.2    Gorry, F.3    Berger, F.4    Chayvialle, J.-A.5
  • 13
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • DOI 10.1016/0304-3959(83)90201-4
    • Zimmermann M: Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983; 16: 109-110. (Pubitemid 13058546)
    • (1983) Pain , vol.16 , Issue.2 , pp. 109-110
    • Zimmermann, M.1
  • 14
    • 0017036162 scopus 로고
    • Chronic catheterization of the spinal subarachnoid space
    • DOI 10.1016/0031-9384(76)90029-9
    • Yaksh TL, Rudy TA: Chronic catheterization of the spinal subarachnoid space. Physiol Behav 1976; 17: 1031-1036. (Pubitemid 8063691)
    • (1976) Physiology and Behavior , vol.17 , Issue.6 , pp. 1031-1036
    • Yaksh, T.L.1    Rudy, T.A.2
  • 15
    • 0026728704 scopus 로고
    • Contribution of protein kinase C to central sensitization and persistent pain following tissue injury
    • Coderre TJ: Contribution of protein kinase C to central sensitization and persistent pain following tissue injury. Neurosci Lett 1992; 140: 181-184.
    • (1992) Neurosci Lett , vol.140 , pp. 181-184
    • Coderre, T.J.1
  • 16
    • 0002946460 scopus 로고    scopus 로고
    • Intracolonic zymosan produces visceral hyperalgesia in the rat that is mediated by spinal NMDA and non-NMDA receptors
    • DOI 10.1016/0006-8993(96)00661-0, PII S0006899396006610
    • Coutinho SV, Meller ST, Gebhart GF: Intracolonic zymosan produces visceral hyperalgesia in the rat that is mediated by spinal NMDA and non-NMDA receptors. Brain Res 1996; 736: 7-15. (Pubitemid 26356457)
    • (1996) Brain Research , vol.736 , Issue.1-2 , pp. 7-15
    • Coutinho, S.V.1    Meller, S.T.2    Gebhart, G.F.3
  • 17
    • 1842608894 scopus 로고    scopus 로고
    • Colonic inflammation decreases thermal sensitivity of the forepaw and hindpaw in the rat
    • DOI 10.1016/j.neulet.2004.02.026, PII S0304394004002101
    • Traub RJ, Wang G: Colonic inflammation decreases thermal sensitivity of the forepaw and hindpaw in the rat. Neurosci Lett 2004; 359: 81-84. (Pubitemid 38446644)
    • (2004) Neuroscience Letters , vol.359 , Issue.1-2 , pp. 81-84
    • Traub, R.J.1    Wang, G.2
  • 19
    • 0032777046 scopus 로고    scopus 로고
    • C-Fos expression in the myenteric plexus, spinal cord and brainstem following injection of formalin in the rat colonic wall
    • Miampamba M, Sharkey AK: C-Fos expression in the myenteric plexus, spinal cord and brainstem following injection of formalin in the rat colonic wall. J Auton Nerv Syst 1999; 77: 140-151.
    • (1999) J Auton Nerv Syst , vol.77 , pp. 140-151
    • Miampamba, M.1    Sharkey, A.K.2
  • 20
    • 0026647529 scopus 로고
    • Spinal and intestinal levels of substance P, calcitonin gene-related peptide and vasoactive intestinal polypeptide following perendoscopic injection of formalin in rat colonic wall
    • Miampamba M, Chery-Croze S, Chayvialle JA: Spinal and intestinal levels of substance P, calcitonin gene-related peptide and vasoactive intestinal polypeptide following perendoscopic injection of formalin in rat colonic wall. Neuropeptides 1992; 22: 73-80.
    • (1992) Neuropeptides , vol.22 , pp. 73-80
    • Miampamba, M.1    Chery-Croze, S.2    Chayvialle, J.A.3
  • 21
    • 0026744376 scopus 로고
    • Visceral nociceptors: A new world order?
    • Cervero F, Janig W: Visceral nociceptors: A new world order? Trends Neurosci 1992; 15: 374-378.
    • (1992) Trends Neurosci , vol.15 , pp. 374-378
    • Cervero, F.1    Janig, W.2
  • 22
    • 0029076498 scopus 로고
    • Visceral pain: Mechanisms of peripheral and central sensitization
    • Cervero F: Visceral pain: Mechanisms of peripheral and central sensitization. Ann Med 1995; 27: 235-239.
    • (1995) Ann Med , vol.27 , pp. 235-239
    • Cervero, F.1
  • 23
    • 0028934006 scopus 로고
    • The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E 2 using microdialysis in conscious rats
    • Malmberg AB, Yaksh TL: The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E 2 using microdialysis in conscious rats. Br J Pharmacol 1995; 114: 1069-1075.
    • (1995) Br J Pharmacol , vol.114 , pp. 1069-1075
    • Malmberg, A.B.1    Yaksh, T.L.2
  • 24
    • 0035056034 scopus 로고    scopus 로고
    • 2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation
    • DOI 10.1016/S0304-3959(01)00258-5, PII S0304395901002585
    • Vetter G, Geisslinger G, Tegeder I: Release of glutamate, nitric oxide and prostaglandin E 2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation. Pain 2001; 92: 213-218. (Pubitemid 32367952)
    • (2001) Pain , vol.92 , Issue.1-2 , pp. 213-218
    • Vetter, G.1    Geisslinger, G.2    Tegeder, I.3
  • 25
    • 0027400778 scopus 로고
    • Amino acids and serotonin are released into the lumbar spinal cord of the anesthetized cat following intradermal capsaicin injections
    • Sorkin LS, McAdoo DJ: Amino acids and serotonin are released into the lumbar spinal cord of the anesthetized cat following intradermal capsaicin injections. Brain Res 1993; 607: 89-98. (Pubitemid 23104951)
    • (1993) Brain Research , vol.607 , Issue.1-2 , pp. 89-98
    • Sorkin, L.S.1    McAdoo, D.J.2
  • 26
    • 0025308929 scopus 로고
    • 2+ in mammalian neurons
    • DOI 10.1016/0165-6147(90)90254-6
    • Mayer ML, Miller RJ: Excitatory amino acid receptors, second messengers and regulation of intracellular Ca 2+ in mammalian neurons. Trends Pharmacol Sci 1990; 11: 254-260. (Pubitemid 20175421)
    • (1990) Trends in Pharmacological Sciences , vol.11 , Issue.6 , pp. 254-260
    • Mayer, M.L.1    Miller, R.J.2
  • 27
    • 0024416291 scopus 로고
    • The family of protein kinase C for signal transduction
    • DOI 10.1001/jama.262.13.1826
    • Nishizuka Y: The Albert Lasker Medical Awards: The family of protein kinase C for signal transduction. JAMA 1989; 262: 1826-1833. (Pubitemid 19239471)
    • (1989) Journal of the American Medical Association , vol.262 , Issue.13 , pp. 1826-1833
    • Nishizuka, Y.1
  • 29
    • 0037474067 scopus 로고    scopus 로고
    • Postsynaptic dorsal column neurons express NK1 receptors following colon inflammation
    • DOI 10.1016/S0306-4522(02)00660-7
    • Palecek J, Paleckova V, Willis WD: Postsynaptic dorsal column neurons express NK1 receptors following colon inflammation. Neuroscience 2003; 116: 565-572. (Pubitemid 36139926)
    • (2003) Neuroscience , vol.116 , Issue.2 , pp. 565-572
    • Palecek, J.1    Paleckova, V.2    Willis, W.D.3
  • 30
    • 68349111767 scopus 로고    scopus 로고
    • PKC-epsilon-dependent potentiation of TTX-resistant Nav1.8 current by neurokinin- 1 receptor activation in rat dorsal root ganglion neurons
    • Cang CL, Zhang H, Zhang YQ, Zhao ZQ: PKC-epsilon-dependent potentiation of TTX-resistant Nav1.8 current by neurokinin- 1 receptor activation in rat dorsal root ganglion neurons. Mol Pain 2009; 5: 33.
    • (2009) Mol Pain , vol.5 , pp. 33
    • Cang, C.L.1    Zhang, H.2    Zhang, Y.Q.3    Zhao, Z.Q.4
  • 32
    • 0036182217 scopus 로고    scopus 로고
    • Mild gastritis alters voltage-sensitive sodium currents in gastric sensory neurons in rats
    • Bielefeldt K, Ozaki N, Gebhart GF: Mild gastritis alters voltage-sensitive sodium currents in gastric sensory neurons in rats. Gastroenterology 2002; 122: 752-761. (Pubitemid 34173827)
    • (2002) Gastroenterology , vol.122 , Issue.3 , pp. 752-761
    • Bielefeldt, K.1    Ozaki, N.2    Gebhart, G.F.3
  • 33
    • 72049107843 scopus 로고    scopus 로고
    • Gap junctions in dorsal root ganglia: Possible contribution to visceral pain
    • Huang TY, Belzer V, Hanani M: Gap junctions in dorsal root ganglia: Possible contribution to visceral pain. Eur J Pain 2010; 14: 49-11.
    • (2010) Eur J Pain , vol.14 , pp. 49-11
    • Huang, T.Y.1    Belzer, V.2    Hanani, M.3
  • 34
    • 0030439407 scopus 로고    scopus 로고
    • 2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice
    • Bilsky EJ, Bernstein RN, Wang ZJ, Sadee W, Porreca F: Effects of naloxone and D-Phe- Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice. J Pharmacol Exp Ther 1996; 277: 484-490. (Pubitemid 27169095)
    • (1996) Journal of Pharmacology and Experimental Therapeutics , vol.277 , Issue.1 , pp. 484-490
    • Bilsky, E.J.1    Bernstein, R.N.2    Wang, Z.3    Sadee, W.4    Porreca, F.5
  • 35
    • 0032873813 scopus 로고    scopus 로고
    • Protein kinase C inhibition blocks the early appearance of vestibular compensation
    • DOI 10.1016/S0006-8993(99)01958-7, PII S0006899399019587
    • Balaban CD, Freilino M, Romero GG: Protein kinase C inhibition blocks the early appearance of vestibular compensation. Brain Res 1999; 845: 97-101. (Pubitemid 29472373)
    • (1999) Brain Research , vol.845 , Issue.1 , pp. 97-101
    • Balaban, C.D.1    Freilino, M.2    Romero, G.G.3
  • 36
    • 3042648414 scopus 로고    scopus 로고
    • A linear signal transduction pathway involving phosphatidylinositol 3-kinase, protein kinase Cε, and MAPK in mesangial cells regulates interferon-γ-induced STAT1α transcriptional activation
    • DOI 10.1074/jbc.M403530200
    • Choudhury GG: A linear signal transduction pathway involving phosphatidylinositol 3-kinase, protein kinase C epsilon, and MAPK in mesangial cells regulates interferon- gamma-induced STAT1 alpha transcriptional activation. J Biol Chem 2004; 279: 27399-27409. (Pubitemid 38812579)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.26 , pp. 27399-27409
    • Choudhury, G.G.1
  • 37
    • 0023713997 scopus 로고
    • Protein kinase C (PKC) inhibitors inhibit primary ( 1-0) but not secondary ( 1-1) or cloned cytotoxic T lymphocytes
    • Howcroft TK, Tatum SM, Cosgrove JM, Lindquist RR: Protein kinase C (PKC) inhibitors inhibit primary (1-0) but not secondary (1-1) or cloned cytotoxic T lymphocytes. Biochem Biophys Res Commun 1988; 154: 1280-1286.
    • (1988) Biochem Biophys Res Commun , vol.154 , pp. 1280-1286
    • Howcroft, T.K.1    Tatum, S.M.2    Cosgrove, J.M.3    Lindquist, R.R.4
  • 38
    • 0022446595 scopus 로고
    • The protein kinase C inhibitors H-7 and H-9 fail to inhibit human neutrophil activation
    • Wright CD, Hoffman MD: The protein kinase C inhibitors H-7 and H-9 fail to inhibit human neutrophil activation. Biochem Biophys Res Commun 1986; 135: 749-755. (Pubitemid 16039963)
    • (1986) Biochemical and Biophysical Research Communications , vol.135 , Issue.3 , pp. 749-755
    • Wright, C.D.1    Hoffman, M.D.2
  • 39
    • 33646026212 scopus 로고    scopus 로고
    • Increased glutamate synaptic transmission in the nucleus raphe magnus neurons from morphine-tolerant rats
    • Bie B, Pan ZZ: Increased glutamate synaptic transmission in the nucleus raphe magnus neurons from morphine-tolerant rats. Mol Pain 2005; 1: 7.
    • (2005) Mol Pain , vol.1 , pp. 7
    • Bie, B.1    Pan, Z.Z.2
  • 40
    • 48549088794 scopus 로고    scopus 로고
    • Continuous delta-opioid receptor activation reduces neuronal voltage-gated sodium channel (NaV1.7) levels through activation of protein kinase C in painful diabetic neuropathy
    • Chattopadhyay M, Mata M, Fink DJ: Continuous delta-opioid receptor activation reduces neuronal voltage-gated sodium channel (NaV1.7) levels through activation of protein kinase C in painful diabetic neuropathy. J Neurosci 2008; 28: 6652-6658.
    • (2008) J Neurosci , vol.28 , pp. 6652-6658
    • Chattopadhyay, M.1    Mata, M.2    Fink, D.J.3
  • 41
    • 5644280204 scopus 로고    scopus 로고
    • Cloning and pharmacological characterization of mouse TRPV1
    • DOI 10.1016/j.neulet.2004.07.058, PII S0304394004009413
    • Correll CC, Phelps PT, Anthes JC, Umland S, Greenfeder S: Cloning and pharmacological characterization of mouse TRPV1. Neurosci Lett 2004; 370: 55-60. (Pubitemid 39369856)
    • (2004) Neuroscience Letters , vol.370 , Issue.1 , pp. 55-60
    • Correll, C.C.1    Phelps, P.T.2    Anthes, J.C.3    Umland, S.4    Greenfeder, S.5
  • 42
    • 0027978054 scopus 로고
    • Effects of protein kinase C activators upon the late stages of the ACTH secretory pathway of AtT-20 cells
    • McFerran BW, Guild SB: Effects of protein kinase C activators upon the late stages of the ACTH secretory pathway of AtT-20 cells. Br J Pharmacol 1994; 113: 171-178. (Pubitemid 24271734)
    • (1994) British Journal of Pharmacology , vol.113 , Issue.1 , pp. 171-178
    • McFerran, B.W.1    Guild, S.B.2
  • 43
    • 0026728704 scopus 로고
    • Contribution of protein kinase C to central sensitization and persistent pain following tissue injury
    • Coderre TJ: Contribution of protein kinase C to central sensitization and persistent pain following tissue injury. Neurosci Lett 1992; 140: 181-184.
    • (1992) Neurosci Lett , vol.140 , pp. 181-184
    • Coderre, T.J.1
  • 47
    • 0037716476 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor type-1 in sensory neurons contributes to induction of chronic enhancement of inflammatory hyperalgesia in rat
    • DOI 10.1046/j.1460-9568.2003.02626.x
    • Parada CA, Yeh JJ, Joseph EK, Levine JD: Tumor necrosis factor receptor type-1 in sensory neurons contributes to induction of chronic enhancement of inflammatory hyperalgesia in rat. Eur J Neurosci 2003; 17: 1847-1852. (Pubitemid 36645334)
    • (2003) European Journal of Neuroscience , vol.17 , Issue.9 , pp. 1847-1852
    • Parada, C.A.1    Yeh, J.J.2    Joseph, E.K.3    Levine, J.D.4
  • 48
    • 0034659718 scopus 로고    scopus 로고
    • Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the ε isozyme of protein kinase C
    • Aley KO, Messing RO, Mochly-Rosen D, Levine JD: Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C. J Neurosci 2000; 20: 4680-4685. (Pubitemid 30396633)
    • (2000) Journal of Neuroscience , vol.20 , Issue.12 , pp. 4680-4685
    • Aley, K.O.1    Messing, R.O.2    Mochly-Rosen, D.3    Levine, J.D.4
  • 49
    • 0033166535 scopus 로고    scopus 로고
    • Specific involvement of PKC-ε in sensitization of the neuronal response to painful heat
    • DOI 10.1016/S0896-6273(00)80813-2
    • Cesare P, Dekker LV, Sardini A, Parker PJ, McNaughton PA: Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat. Neuron 1999; 23: 617-624. (Pubitemid 29359931)
    • (1999) Neuron , vol.23 , Issue.3 , pp. 617-624
    • Cesare, P.1    Dekker, L.V.2    Sardini, A.3    Parker, P.J.4    McNaughton, P.A.5
  • 50
    • 0024418739 scopus 로고
    • Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture
    • Burgess GM, Mullaney I, McNeill M, Dunn PM, Rang HP: Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture. J Neurosci 1989; 9: 3314-3325. (Pubitemid 19260844)
    • (1989) Journal of Neuroscience , vol.9 , Issue.9 , pp. 3314-3325
    • Burgess, G.M.1    Mullaney, I.2    McNeill, M.3    Dunn, P.M.4    Rang, H.P.5
  • 51
    • 34848814724 scopus 로고    scopus 로고
    • PLC-β3 signals upstream of PKCε in acute and chronic inflammatory hyperalgesia
    • DOI 10.1016/j.pain.2007.01.027, PII S030439590700053X
    • Joseph EK, Bogen O, essandri-Haber N, Levine JD: PLC-beta 3 signals upstream of PKC epsilon in acute and chronic inflammatory hyperalgesia. Pain 2007; 132: 67-73. (Pubitemid 47494562)
    • (2007) Pain , vol.132 , Issue.1-2 , pp. 67-73
    • Joseph, E.K.1    Bogen, O.2    Alessandri-Haber, N.3    Levine, J.D.4
  • 52
    • 0037134417 scopus 로고    scopus 로고
    • Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cε and identification of two target serine residues
    • DOI 10.1074/jbc.C200104200
    • Numazaki M, Tominaga T, Toyooka H, Tominaga M: Direct phosphorylation of capsaicin receptor VR1 by protein kinase C-epsilon and identification of two target serine residues. J Biol Chem 2002; 277: 13375-13378. (Pubitemid 34967929)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.16 , pp. 13375-13378
    • Numazaki, M.1    Tominaga, T.2    Toyooka, H.3    Tominaga, M.4
  • 53
    • 38149119710 scopus 로고    scopus 로고
    • Protein kinase C-beta inhibitor enzastaurin (LY317615.HCI) enhances radiation control of murine breast cancer in an orthotopic model of bone metastasis
    • Dudek AZ, Zwolak P, Jasinski P, Terai K, Gallus NJ, Ericson ME, Farassati F: Protein kinase C-beta inhibitor enzastaurin (LY317615.HCI) enhances radiation control of murine breast cancer in an orthotopic model of bone metastasis. Invest New Drugs 2008; 26: 13-24.
    • (2008) Invest New Drugs , vol.26 , pp. 13-24
    • Dudek, A.Z.1    Zwolak, P.2    Jasinski, P.3    Terai, K.4    Gallus, N.J.5    Ericson, M.E.6    Farassati, F.7
  • 54
    • 1542269754 scopus 로고    scopus 로고
    • Peripheral nerve injury induces trans-synaptic modification of channels, receptors and signal pathways in rat dorsal spinal cord
    • DOI 10.1111/j.0953-816X.2004.03121.x
    • Yang L, Zhang FX, Huang F, Lu YJ, Li GD, Bao L, Xiao HS, Zhang X: Peripheral nerve injury induces trans-synaptic modification of channels, receptors and signal pathways in rat dorsal spinal cord. Eur J Neurosci 2004; 19: 871-883. (Pubitemid 38297024)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.4 , pp. 871-883
    • Yang, L.1    Zhang, F.-X.2    Huang, F.3    Lu, Y.-J.4    Li, G.-D.5    Bao, L.6    Xiao, H.-S.7    Zhang, X.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.