Roles of the endoplasmic reticulum stress transducer OASIS in fracture healing

Bone

Volumn 49, Issue 4, 2011, Pages 724-732

  Funamoto, Taro ^a   Sekimoto, Tomohisa ^a   Murakami, Tomohiko ^a   Kurogi, Syuji ^a   Imaizumi, Kazunori ^a   Chosa, Etsuo ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Endoplasmic reticulum; Fracture healing; OASIS; Osteoblast; Type I collagen

Indexed keywords

BONE MATRIX PROTEIN; COLLAGEN TYPE 1; ENDOPLASMIC RETICULUM STRESS TRANSDUCER PROTEIN; MATRIX PROTEIN; MESSENGER RNA; OLD ASTROCYTE SPECIFICALLY INDUCED SUBSTANCE PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE STRENGTH; BONE VOLUME; CALLUS; CELL EXPANSION; CONTROLLED STUDY; ELECTRON MICROSCOPY; ELECTROPHORESIS; ENDOPLASMIC RETICULUM; FRACTURE HEALING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICRO-COMPUTED TOMOGRAPHY; MORPHOGENESIS; MOUSE; NONHUMAN; ORGAN SIZE; OSTEOBLAST; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BONY CALLUS; COLLAGEN TYPE I; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMORAL FRACTURES; FRACTURE HEALING; GENE EXPRESSION REGULATION; MICE; NERVE TISSUE PROTEINS; OSTEOBLASTS; X-RAY MICROTOMOGRAPHY;

EID: 80052290474     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.06.012     Document Type: Article

References (26)

1. Shapiro F. Bone development and its relation to fracture repair. The role of mesenchymal osteoblasts and surface osteoblasts. Eur Cell Mater 2008, 15:53-76.
2. Tsiridis E., Upadhyay N., Giannoudis P. Molecular aspects of fracture healing: which are the important molecules?. Injury 2007, 38(SUPPL 1):S11-S25.
3. Cho T., Gerstenfeld L., Einhorn T. Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res 2002, 17:513-520.
4. Tsuji K., Bandyopadhyay A., Harfe B., Cox K., Kakar S., Gerstenfeld L., et al. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet 2006, 38:1424-1429.
5. Viguet-Carrin S., Garnero P., Delmas P. The role of collagen in bone strength. Osteoporos Int 2006, 17:319-336.
6. Davison K., Siminoski K., Adachi J., Hanley D., Goltzman D., Hodsman A., et al. Bone strength: the whole is greater than the sum of its parts. Semin Arthritis Rheum 2006, 36:22-31.
7. Xu K., Nowak I., Kirchner M., Xu Y. Recombinant collagen studies link the severe conformational changes induced by osteogenesis imperfecta mutations to the disruption of a set of interchain salt bridges. J Biol Chem 2008, 283:34337-34344.
8. Lisse T., Thiele F., Fuchs H., Hans W., Przemeck G., Abe K., et al. ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta. PLoS Genet 2008, 4:e7.
9. Morello R., Bertin T., Chen Y., Hicks J., Tonachini L., Monticone M., et al. CRTAP is required for prolyl 3- hydroxylation and mutations cause recessive osteogenesis imperfecta. Cell 2006, 127:291-304.
10. Cabral W., Chang W., Barnes A., Weis M., Scott M., Leikin S., et al. Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta. Nat Genet 2007, 39:359-365.
11. Nagai N., Hosokawa M., Itohara S., Adachi E., Matsushita T., Hosokawa N., et al. Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. J Cell Biol 2000, 150:1499-1506.
12. Murakami T., Saito A., Hino S., Kondo S., Kanemoto S., Chihara K., et al. Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation. Nat Cell Biol 2009, 11:1205-1211.
13. Honma Y., Kanazawa K., Mori T., Tanno Y., Tojo M., Kiyosawa H., et al. Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue. Brain Res Mol Brain Res 1999, 69:93-103.
14. Nikaido T., Yokoya S., Mori T., Hagino S., Iseki K., Zhang Y., et al. Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Histochem Cell Biol 2001, 116:141-148.
15. Kondo S., Murakami T., Tatsumi K., Ogata M., Kanemoto S., Otori K., et al. OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes. Nat Cell Biol 2005, 7:186-194.
16. Murakami T., Kondo S., Ogata M., Kanemoto S., Saito A., Wanaka A., et al. Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress. J Neurochem 2006, 96:1090-1100.
17. Sekiya H., Murakami T., Saito A., Hino S., Tsumagari K., Ochiai K., et al. Effects of the bisphosphonate risedronate on osteopenia in OASIS-deficient mice. J Bone Miner Metab 2010, 28:384-394.
18. Lyons K.M., Hogan B.L., Robertson E.J. Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech Dev 1995, 50:71-83.
19. Solloway M.J., Dudley A.T., Bikoff E.K., Lyons K.M., Hogan B.L., Robertson E.J. Mice lacking Bmp6 function. Dev Genet 1998, 22:321-339.
20. Katagiri T., Boorla S., Frendo J.L., Hogan B.L., Karsenty G. Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice. Dev Genet 1998, 22:340-348.
21. Gabet Y., Müller R., Regev E., Sela J., Shteyer A., Salisbury K., et al. Osteogenic growth peptide modulates fracture callus structural and mechanical properties. Bone 2004, 35:65-73.
22. Murakami T., Hino S., Nishimura R., Yoneda T., Wanaka A., Imaizumi K. Distinct mechanisms are responsible for osteopenia and growth retardation in OASIS-deficient mice. Bone 2011, 48:514-523.
23. Schindeler A., McDonald M., Bokko P., Little D. Bone remodeling during fracture repair: the cellular picture. Semin Cell Dev Biol 2008, 19:459-466.
24. Suda T., Takahashi N., Udagawa N., Jimi E., Gillespie M., Martin T. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 1999, 20:345-357.
25. Sitara D., Aliprantis A. Transcriptional regulation of bone and joint remodeling by NFAT. Immunol Rev 2010, 233:286-300.
26. Takayanagi H., Kim S., Koga T., Nishina H., Isshiki M., Yoshida H., et al. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell 2002, 3:889-901.