Anti-HIV siamycin i directly inhibits autophosphorylation activity of the bacterial FsrC quorum sensor and other ATP-dependent enzyme activities

FEBS Letters

Volumn 585, Issue 17, 2011, Pages 2660-2664

  Ma, Pikyee ^a,c   Nishiguchi, Kenzo ^b   Yuille, Hayley M ^a   Davis, Lianne M ^a   Nakayama, Jiro ^b   Phillips Jones, Mary K ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b KYUSHU UNIVERSITY   (Japan)

^c INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

Author keywords

Bacterial two component signal transduction system; Enterococcus faecalis; FsrC; HIV inhibitor; Quorum sensing; Siamycin I

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; BACTERIAL ENZYME; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; PHEROMONE; PROTEIN HISTIDINE KINASE; SENSOR HISTIDINE KINASE FSRC; SENSOR HISTIDINE KINASE PRRB; SIAMYCIN I; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; COW; ENTEROCOCCUS FAECALIS; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; QUORUM SENSING; RHODOBACTER SPHAEROIDES; SWINE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BACTERIAL PROTEINS; BETA-GALACTOSIDASE; CATTLE; ENTEROCOCCUS FAECALIS; ENZYME ACTIVATION; ENZYME INHIBITORS; KINETICS; MICROBIAL SENSITIVITY TESTS; PEPTIDES; PHOSPHORYLATION; QUORUM SENSING; RHODOBACTER SPHAEROIDES; SWINE;

BACTERIA (MICROORGANISMS); BOVINAE; ENTEROCOCCUS FAECALIS; RHODOBACTER SPHAEROIDES; SUS;

EID: 80052263187     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.07.026     Document Type: Article

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