Effects of Enterococcus faecalis fsr genes on production of gelatinase and a serine protease and virulence

Infection and Immunity

Volumn 68, Issue 5, 2000, Pages 2579-2586

  Qin, Xiang ^a   Singh, Kavindra V ^a   Weinstock, George M ^a   Murray, Barbara E ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE; SERINE PROTEINASE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL VIRULENCE; ENTEROCOCCUS FAECALIS; ENZYME SYNTHESIS; GENE MUTATION; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; BLOTTING, NORTHERN; DATABASES, FACTUAL; DIHYDROPTERIDINE REDUCTASE; DISEASE MODELS, ANIMAL; DNA, BACTERIAL; DNA-BINDING PROTEINS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI PROTEINS; GELATINASES; GENES, BACTERIAL; GENETIC COMPLEMENTATION TEST; HEMEPROTEINS; MICE; MOLECULAR SEQUENCE DATA; NADH, NADPH OXIDOREDUCTASES; PERITONITIS; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SERINE ENDOPEPTIDASES; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; VIRULENCE;

EID: 0034061486     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.5.2579-2586.2000     Document Type: Article

References (26)

1. Abdelnour, A., S. Arvidson, T. Bremell, C. Ryden, and A. Tarkowski. 1993. The accessory gene regulator (agr) controls Staphylococcus aureus virulence in a murine arthritis model. Infect. Immun. 61:3879-3885.
2. Beliveau, C., C. Potvin, J. Trudel, A. Asselin, and G. Bellemare. 1991. Cloning, sequencing, and expression in Escherichia coli of a Streptococcus faecalis autolysin. J. Bacteriol. 173:5619-5623.
3. Birnboim, H. C., and J. Doly. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1513-1523.
4. Coque, T. M., J. E. Patterson, J. M. Steckelberg, and B. E. Murray. 1995. Incidence of hemolysin, gelatinase and aggregative substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons. J. Infect. Dis. 171:1223-1229.
5. Ji, G., R. Beavis, and R. P. Novick. 1997. Bacterial interference caused by autoinducing variants. Science 276:2027-2030.
6. Ji, G., R. C. Beavis, and R. P. Novick. 1995. Cell density control of staphylococcal virulence mediated by an octapeptide pheromone. Proc. Natl. Acad. Sci. USA 92:12055-12059.
7. Li, X., G. M. Weinstock, and B. E. Murray. 1995. Generation of auxotrophic mutants of Enterococcus faecalis. J. Bacteriol. 177:6866-6873.
8. Lindberg, M., K. Jonsson, H. Muller, H. Jonsson, C. Signas, M. Hook, R. Raja, G. Raucci, and G. M. Anantharamaiah. 1990. Fibronectin-binding proteins in Staphylococcus aureus, p. 343-356. In R. P. Novick (ed.), Molecular biology of the staphylococci. VCH, New York, N.Y.
9. Murray, B. E. 1990. The life and times of the enterococcus. Clin. Microbiol. Rev. 3:46-65.
10. Murray, B. E., K. V. Singh, R. P. Ross, J. D. Heath, G. M. Dunny, and G. M. Weinstock. 1993. Generation of restriction map of Enterococcus faecalis strain OG1 and investigation of growth requirements and regions encoding biosynthetic function. J. Bacteriol. 175:5216-5223.
11. Novick, R. P., S. J. Projan, J. Kornblum, H. F. Ross, G. Ji, B. Kreiswirth, F. Vandenesch, and S. Moghazeh. 1995. The agr P2 operon: an autocatalytic sensory transduction system in Staphylococcus aureus. Mol. Gen. Genet. 248:446-458.
12. Novick, R. P., H. F. Ross, S. J. Projan, J. Kornblum, B. Kreiswirth, and S. Moghazeh. 1993. Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule. EMBO J. 12:3967-3975.
13. Otto, M., R. SuBmuth, G. Jung, and F. Golz. 1998. Structure of the pheromone peptide of the Staphylococcus epidermidis agr system. FEBS Lett. 424:89-94.
14. Peng, H.-L., R. P. Novick, B. Kreiswirth, J. Kornblum, and P. Schlievert. 1988. Cloning, characterization, and sequencing of an accessory gene regulator (agr) in Staphylococcus aureus. J. Bacteriol. 170:4365-4372.
15. Prober, J. M., G. L. Trainor, R. J. Dam, F. W. Hobbs, C. W. Robertson, R. J. Zagursky, A. J. Cocuzza, M. A. Jensen, and K. Baumeister. 1987. A system for rapid DNA sequencing with fluorescent chain-terminating dideoxynucleotides. Science 238:336-341.
16. Recsei, P., B. Kreiswirth, M. O'Reilly, P. Schlievert, A. Gruss, and R. P. Novick. 1985. Regulation of exoprotein gene expression by agr. Mol. Gen. Genet. 202:58-61.
17. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
18. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
19. Singh, K. V., X. Qin, G. M. Weinstock, and B. E. Murray. 1998. Generation and testing of mutants of Enterococcus faecalis in a mouse peritonitis model. J. Infect. Dis. 178:1416-1420.
20. Stock, J. B., A. J. Ninfa, and A. M. Stock. 1989. Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol. Rev. 53:450-490.
21. Su, Y. A., M. C. Sulavik, P. He, K. K. Makinen, P.-L. Makinen, S. Fiedler, R. Wirth, and D. B. Clewell. 1991. Nucleotide sequence of the gelatinase gene (gelE) from Enterococcus faecalis subsp. liquefaciens. Infect. Immun. 59:415-420.
22. Tegmark, K., E. Morfeldt, and S. Arvidson. 1998. Regulation of agr-dependent virulence genes in Staphylococcus aureus by RNAIII from coagulase-negative staphylococci. J. Bacteriol. 180:3181-3186.
23. Trieu-Cuot, P., C. Carlier, C. Poyart-Salmeron, and P. Courvalin. 1991. Shuttle vectors containing a multiple cloning site and a lacZα gene for conjugal transfer of DNA from Escherichia coli to gram-positive bacteria. Gene 102:99-104.
24. Van Wamel, W. J., G. Van Rossum, J. Verhoef, C. M. Vandenbroucke-Grauls, and A. C. Fluit. 1998. Cloning and characterization of an accessory gene regulator (agr)-like locus from Staphylococcus epidermidis. FEMS Microbiol. Lett. 163:1-9.
25. Vandenesch, F., S. Projan, B. Kreiswirth, J. Etienne, and R. P. Novick. 1993. agr-related sequences in Staphylococcus ludunensis. FEMS Microbiol. Lett. 111:115-122.
26. Wilson, K. 1990. Current protocols in molecular biology, p. 2.4.1-2.4.2. Green Publishing Associates, Brooklyn, N.Y.