Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes

Journal of Allergy and Clinical Immunology

Volumn 128, Issue 3, 2011, Pages

  Brand, Stephanie ^a   Teich, René ^b   Dicke, Tanja ^a   Harb, Hani ^a   Yildirim, Ali Ö ^c   Tost, Jörg ^d,e   Schneider Stock, Regine ^f   Waterland, Robert A ^g   Bauer, Uta Maria ^a   Von Mutius, Erika ^h   Garn, Holger ^a   Pfefferle, Petra I ^a   Renz, Harald ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^e FONDATION JEAN DAUSSET CEPH   (France)

^f UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^g CHILDREN S NUTRITION RESEARCH CENTER   (United States)

^h LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

allergy; Asthma; epigenetics; histone acetylation; hygiene hypothesis; T cells

Indexed keywords

ACYLTRANSFERASE INHIBITOR; CONSERVED NONCODING SEQUENCE 1; GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; GARCINOL; HISTONE H4; INTERLEUKIN 4; INTERLEUKIN 5; NUCLEOTIDE; UNCLASSIFIED DRUG;

ACINETOBACTER LWOFFII; ANIMAL EXPERIMENT; ARTICLE; ASTHMA; BACTERIAL STRAIN; CD4+ T LYMPHOCYTE; DNA MODIFICATION; ENVIRONMENTAL EXPOSURE; EPIGENETICS; FARMING SYSTEM; FEMALE; GENE EXPRESSION; HISTONE ACETYLATION; MICROORGANISM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PROTEIN DEPLETION; TH1 CELL; TH2 CELL;

EID: 80052260940     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.04.035     Document Type: Article

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