Formulation optimization of estradiol microemulsion using response surface methodology

Journal of Pharmaceutical Sciences

Volumn 100, Issue 10, 2011, Pages 4383-4389

  Tsai, Yi Hung ^a   Fu, Li Tse ^a   Huang, Chi Te ^a   Chang, Jui Sheng ^a   Huang, Yaw Bin ^a   Wu, Pao Chu ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Estradiol; Formulation; Microemulsion; Permeability; Response surface methodology; Skin; Transdermal drug delivery

Indexed keywords

ALCOHOL; ESTRADIOL; MYRISTIC ACID ISOPROPYL ESTER; WATER; EMULSION; MYRISTIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG PENETRATION; IN VITRO STUDY; MICROEMULSION; NONHUMAN; RAT; RESPONSE SURFACE METHOD; SKIN; VISCOSITY; ANIMAL; CHEMISTRY; EMULSION; INTRADERMAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; PERMEABILITY; PHARMACEUTICS; PROCEDURES; SKIN ABSORPTION; SPRAGUE DAWLEY RAT; STATISTICAL MODEL;

ADMINISTRATION, CUTANEOUS; ANIMALS; CHEMISTRY, PHARMACEUTICAL; EMULSIONS; ESTRADIOL; ETHANOL; IN VITRO TECHNIQUES; MODELS, STATISTICAL; MYRISTATES; PERMEABILITY; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION; TECHNOLOGY, PHARMACEUTICAL; VISCOSITY; WATER;

EID: 80052260703     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22600     Document Type: Article

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