-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus D, Linde-Zwirble W, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001; 29:1303-10.
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.1
Linde-Zwirble, W.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
2
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001; 344:699-709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
3
-
-
0036840629
-
Risk and the efficacy of antiinflammatory agents: Retrospective and confirmatory studies of sepsis
-
Eichacker PQ, Parent C, Kalil A, et al. Risk and the efficacy of antiinflammatory agents: retrospective and confirmatory studies of sepsis. Am J Respir Crit Care Med. 2002; 166:1197-205.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 1197-1205
-
-
Eichacker, P.Q.1
Parent, C.2
Kalil, A.3
-
4
-
-
25444492831
-
Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death
-
Abraham E, Laterre PF, Garg R, et al. Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. N Engl J Med. 2005; 353:1332-41.
-
(2005)
N Engl J Med
, vol.353
, pp. 1332-1341
-
-
Abraham, E.1
Laterre, P.F.2
Garg, R.3
-
5
-
-
20844459638
-
Fluvast- atin reduces the 4-year cardiac risk in patients with multivessel disease
-
Lemos PA, de Feyter PJ, Serruys PW, et al. Fluvast- atin reduces the 4-year cardiac risk in patients with multivessel disease. Int J Cardiol. 2005; 98:479-86.
-
(2005)
Int J Cardiol
, vol.98
, pp. 479-486
-
-
Lemos, P.A.1
de Feyter, P.J.2
Serruys, P.W.3
-
6
-
-
4143083577
-
Prior statin therapy is associated with a decreased rate of severe sepsis
-
Almog Y, Shefer A, Novack V, et al. Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 2004; 110:880-5.
-
(2004)
Circulation
, vol.110
, pp. 880-885
-
-
Almog, Y.1
Shefer, A.2
Novack, V.3
-
8
-
-
29844445926
-
Statin therapy is associated with fewer deaths in patients with bacteraemia
-
Kruger P, Fitzsimmons K, Cook D, Jones M, Nimmo G. Statin therapy is associated with fewer deaths in patients with bacteraemia. Intensive Care Med. 2006; 32:75-9.
-
(2006)
Intensive Care Med
, vol.32
, pp. 75-79
-
-
Kruger, P.1
Fitzsimmons, K.2
Cook, D.3
Jones, M.4
Nimmo, G.5
-
9
-
-
29844438975
-
Statin therapy prior to ICU admission: Protection against infection or a severity marker?
-
Fernandez R, De Pedro VJ, Artigas A. Statin therapy prior to ICU admission: protection against infection or a severity marker? Intensive Care Med. 2006; 32:160-4.
-
(2006)
Intensive Care Med
, vol.32
, pp. 160-164
-
-
Fernandez, R.1
De Pedro, V.J.2
Artigas, A.3
-
10
-
-
34249287370
-
Statins do not improve short-term survival in an oriental population with sepsis
-
Yang KC, Chien JY, Tseng WK, Hsueh PR, Yu CJ, Wu CC. Statins do not improve short-term survival in an oriental population with sepsis. Am J Emerg Med. 2007; 25:494-501.
-
(2007)
Am J Emerg Med
, vol.25
, pp. 494-501
-
-
Yang, K.C.1
Chien, J.Y.2
Tseng, W.K.3
Hsueh, P.R.4
Yu, C.J.5
Wu, C.C.6
-
11
-
-
33750360916
-
Simvastatin suppresses endotoxin-induced upregulation of tolllike receptors 4 and 2 in vivo
-
Niessner A, Steiner S, Speidl WS, et al. Simvastatin suppresses endotoxin-induced upregulation of tolllike receptors 4 and 2 in vivo. Atherosclerosis 2006; 189:408-13.
-
(2006)
Atherosclerosis
, vol.189
, pp. 408-413
-
-
Niessner, A.1
Steiner, S.2
Speidl, W.S.3
-
12
-
-
34247150706
-
Statins and sepsis: Multiple modifications at multiple levels
-
Terblanche M, Almog Y, Rosenson RS, Smith TS, Hackam DG. Statins and sepsis: multiple modifications at multiple levels. Lancet Infect Dis. 2007; 7:358-68.
-
(2007)
Lancet Infect Dis
, vol.7
, pp. 358-368
-
-
Terblanche, M.1
Almog, Y.2
Rosenson, R.S.3
Smith, T.S.4
Hackam, D.G.5
-
13
-
-
33644595198
-
Effects of atorvastatin on systemic inflammatory response after coronary bypass surgery
-
Chello M, Patti G, Candura D, et al. Effects of atorvastatin on systemic inflammatory response after coronary bypass surgery. Crit Care Med. 2006; 34:660-7.
-
(2006)
Crit Care Med
, vol.34
, pp. 660-667
-
-
Chello, M.1
Patti, G.2
Candura, D.3
-
14
-
-
2642553075
-
HMG-CoA reductase inhibitor simvastatin profoundly improves survival in a murine model of sepsis
-
Merx MW, Liehn EA, Janssens U, et al. HMG-CoA reductase inhibitor simvastatin profoundly improves survival in a murine model of sepsis. Circulation 2004; 109:2560-5.
-
(2004)
Circulation
, vol.109
, pp. 2560-2565
-
-
Merx, M.W.1
Liehn, E.A.2
Janssens, U.3
-
15
-
-
34447559811
-
Performance of severity of illness scoring systems in emergency department patients with infection
-
Howell MD, Donnino MW, Talmor D, Clardy P, Ngo L, Shapiro NI. Performance of severity of illness scoring systems in emergency department patients with infection. Acad Emerg Med. 2007; 14:709-14.
-
(2007)
Acad Emerg Med
, vol.14
, pp. 709-714
-
-
Howell, M.D.1
Donnino, M.W.2
Talmor, D.3
Clardy, P.4
Ngo, L.5
Shapiro, N.I.6
-
16
-
-
0037351815
-
Mortality in Emergency Department Sepsis (MEDS) score: A prospectively derived and validated clinical prediction rule
-
Shapiro NI, Wolfe RE, Moore RB, Smith E, Burdick E, Bates DW. Mortality in Emergency Department Sepsis (MEDS) score: a prospectively derived and validated clinical prediction rule. Crit Care Med. 2003; 31:670-5.
-
(2003)
Crit Care Med
, vol.31
, pp. 670-675
-
-
Shapiro, N.I.1
Wolfe, R.E.2
Moore, R.B.3
Smith, E.4
Burdick, E.5
Bates, D.W.6
-
17
-
-
0023092594
-
A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
-
Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987; 40:373-83.
-
(1987)
J Chronic Dis
, vol.40
, pp. 373-383
-
-
Charlson, M.E.1
Pompei, P.2
Ales, K.L.3
MacKenzie, C.R.4
-
18
-
-
10744233133
-
Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha- induced thrombomodulin downregulation
-
Shi J, Wang J, Zheng H, et al. Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha- induced thrombomodulin downregulation. Blood Coagul Fibrinolysis. 2003; 14:575-85.
-
(2003)
Blood Coagul Fibrinolysis
, vol.14
, pp. 575-585
-
-
Shi, J.1
Wang, J.2
Zheng, H.3
-
19
-
-
33846930580
-
Effects of simvastatin in abdominal sepsis in rats
-
Souza Neto JL, Araujo Filho I, Rego AC, et al. Effects of simvastatin in abdominal sepsis in rats. Acta Cir Bras. 2006; 21(Suppl 4):8-12.
-
(2006)
Acta Cir Bras
, vol.21
, Issue.SUPPL. 4
, pp. 8-12
-
-
Souza Neto, J.L.1
Araujo Filho, I.2
Rego, A.C.3
-
20
-
-
33947305316
-
Simvasta- tin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery
-
Chello M, Anselmi A, Spadaccio C, et al. Simvasta- tin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery. Ann Thorac Surg. 2007; 83:1374-80.
-
(2007)
Ann Thorac Surg
, vol.83
, pp. 1374-1380
-
-
Chello, M.1
Anselmi, A.2
Spadaccio, C.3
-
21
-
-
33847729386
-
Beneficial effects of statins on the microcirculation during sepsis: The role of nitric oxide
-
McGown CC, Brookes ZL. Beneficial effects of statins on the microcirculation during sepsis: the role of nitric oxide. Br J Anaesth. 2007; 98:163-75.
-
(2007)
Br J Anaesth
, vol.98
, pp. 163-175
-
-
McGown, C.C.1
Brookes, Z.L.2
-
22
-
-
9344256068
-
Simvastatin prevents vascular hyporeactivity during inflammation
-
Pleiner J, Schaller G, Mittermayer F, et al. Simvastatin prevents vascular hyporeactivity during inflammation. Circulation 2004; 110:3349-54.
-
(2004)
Circulation
, vol.110
, pp. 3349-3354
-
-
Pleiner, J.1
Schaller, G.2
Mittermayer, F.3
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