Intraindividual Variability in HIV Infection: Evidence for Greater Neurocognitive Dispersion in Older HIV Seropositive Adults

Neuropsychology

Volumn 25, Issue 5, 2011, Pages 645-654

  Morgan, Erin E ^a   Woods, Steven Paul ^a   Delano Wood, Lisa ^a,b   Bondi, Mark W ^a,b   Grant, Igor ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Aging; HIV; Neuropsychological assessment; Variability

Indexed keywords

ADULT; AGING; ARTICLE; CLINICAL ASSESSMENT; COGNITION; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHOLOGY; PRIORITY JOURNAL; SERODIAGNOSIS; TASK PERFORMANCE;

ADULT; AGING; CASE-CONTROL STUDIES; CLUSTER ANALYSIS; COGNITION DISORDERS; FEMALE; HIV SEROPOSITIVITY; HUMANS; INDIVIDUALITY; MALE; MENTAL PROCESSES; NEUROPSYCHOLOGICAL TESTS; REFERENCE VALUES;

EID: 80052227468     PISSN: 08944105     EISSN: 19311559     Source Type: Journal    
DOI: 10.1037/a0023792     Document Type: Article

References (70)

1. Achim C., Adame A., Dumaop W., Everall I.P., Masliah E., the Neurobehavioral Research Center Increased accumulation of intraneuronal amyloid beta in HIV-infected patients. Journal of Neuroimmune Pharmacology 2009, 4:190-199.
2. American Psychological Association Diagnostic and Statistical Manual of Mental Disorders 1994, Author, Washington, DC. 4th ed.
3. Antinori A., Arendt G., Becker J.T., Brew B.J., Byrd D.A., Cherner M., Wojna V.E. Updated research nosology for HIV-associated neurocognitive disorders. Neurology 2007, 69:1789-1799.
4. Barclay T.R., Hinkin C.H., Castellon S.A., Mason K.I., Reinhard M.J., Marion S.D. Age-associated predictors of medication adherence in HIV-positive adults: Health beliefs, self-efficacy, and neurocognitive status. Health Psychology 2007, 26:40-49.
5. Becker J.T., Lopes O.L., Dew M.A., Aizenstein H.J. Prevalence of cognitive disorders differs as a function of age in HIV virus infection. AIDS 2004, 18:S11-S18.
6. Benton A.L., Hamsher K., Sivan A.B. Multilingual Aphasia Examination 1994, AJA Associates, Iowa City, IA. 3rd ed.
7. Bhaskaran K., Mussini C., Antinori A., Walker A.S., Dorrucci M., Sabin C., CASCADE Collaboration Changes in the incidence and predictors of human immunodeficiency virus-associated dementia in the era of highly active antiretroviral therapy. Annals of Neurology 2008, 63:213-221.
8. Brew B.J., Crowe S.M., Landay A., Cysique L.A., Guillemin G. Neurodegeneration and ageing in the HAART era. Journal of Neuroimmune Pharmacology 2009, 4:163-174.
9. Bunce D., Anstey K.J., Christensen H., Dear K., Wen W., Sachdev P. White matter hyperintensities and within-person variability in community-dwelling adults aged 60-64 years. Neuropsychologia 2007, 45:2009-2015.
10. Burke S.N., Barnes C.A. Neural plasticity in the ageing brain. Nature Reviews Neuroscience 2006, 7:30-40.
11. Burton C.L., Strauss E., Hultsch D.F., Moll A., Hunter M.A. Intraindividual variability as a marker of neurological dysfunction: A comparison of Alzheimer's disease and Parkinson's disease. Journal of Clinical and Experimental Neuropsychology 2006, 28:67-83.
12. Butters N., Grant I., Haxby J., Judd L.L., Martin A., McClelland J., Stover E. Assessment of AIDS-related cognitive changes: Recommendations of the NIMH workshop on neuropsychological assessment approaches. Journal of Clinical and Experimental Neuropsychology 1990, 12:963-978.
13. Carey C.L., Woods S.P., Rippeth J.D., Gonzalez R., Moore D.J., Marcotte T.D., HNRC Group Initial validation of a screening battery for the detection of HIV-associated neurocognitive impairment. The Clinical Neuropsychologist 2004, 18:234-248.
14. Centers for Disease Control HIV/AIDS surveillance report, 2005 2007, 1-63. U.S. Department of Health and Human Services, CDC, Atlanta.
15. Centers for Disease Control HIV/AIDS surveillance report, 2007 2009, 1-65. U.S. Department of Health and Human Services, CDC, Atlanta.
16. Chang L., Lee P.L., Yiannoutsos C., HIV MRS Consortium A multicenter in vivo proton-MRS study of HIV-associated dementia and its relationship to age. Neuroimage 2004, 23:1336-1347.
17. Cherner M., Ellis R.J., Lazzaretto D., Young C., Mindt A.R., Atkinson J.H., HNRC Group Effects of HIV-1 infection and aging on neurobehavioral functioning: Preliminary findings. AIDS 2004, 18:S27-S34.
18. Christensen H., MacKinnon A.J., Korten A.E., Jorm A.F., Henderson A.S., Jacomb P. Dispersion in cognitive ability as a function of age: A longitudinal study of an elderly community sample. Aging, Neuropsychology, & Cognition 1999, 6:214-228.
19. Clifford D.B., Fagan A.M., Holtzman D.M., Morris J.C., Teshome M., Shah A.R., Kauwe J.S. CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease. Neurology 2009, 73:1982-1987.
20. Culbertson W.C., Zillmer E.A. The Tower of London, Drexel University, Research Version: Examiner's Manual 2001, Multi-Health Systems, North Tonawanda, NY.
21. Dawes S., Suarez P., Casey C.Y., Cherner M., Marcotte T.D., Letendre S., HNRC Group Variable patterns of neuropsychological performance in HIV-1 infection. Journal of Clinical and Experimental Neuropsychology 2008, 30:613-626.
22. Delis D.C., Kramer J.H., Kaplan E., Ober B.A. The California Verbal Learning Test, 2nd Edition 2000, The Psychological Corporation, San Antonio, TX.
23. Ernst T., Chang L. Effect of aging on brain metabolism in antiretroviral-naïve HIV patients. AIDS 2004, 18:S61-S67.
24. Ettenhofer M.L., Foley J., Behdin N., Levine A.J., Castellon S.A., Hinkin C.H. Reaction time variability in HIV-positive individuals. Archives of Clinical Neuropsychology 2009, 25:791-798.
25. Everall I.P., Hansen L.A., Masliah E. The shifting patterns of HIV encephalitis neuropathology. Neurotoxicity Research 2009, 8:51-61.
26. Gladsjo J.A., Schuman C.C., Evans J.D., Peavy G.M., Miller S.W., Heaton R.K. Norms for letter and category fluency: Demographic corrections for age, education, and ethnicity. Assessment 1999, 6:147-178.
27. Goodglass H., Kaplan E., Barresi B. Boston Diagnostic Aphasia Examination, 3rd Edition 2001, Lippincott Williams & Wilkins, Philadelphia, PA.
28. Heaton R.K., Clifford D.B., Franklin D.R., Woods S.P., Ake C., Vaida F., CHARTER Group HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology 2010, 75:2087-2096.
29. Hilborn J.V., Strauss E., Hultsch D.F., Hunter M.A. Intraindividual variability across cognitive domains: Investigation of dispersion levels and performance profiles in older adults. Journal of Clinical and Experimental Neuropsychology 2009, 31:412-424.
30. Hinkin C.H., Hardy D.J., Mason K.L., Castellon S.A., Durvasula R.S., Larn M.N., Stefaniak M. Medication adherence in HIV-infected adults: Effect of patient age, cognitive status, and substance abuse. AIDS 2004, 1:S19-S25.
31. Hultsch D.F., MacDonald S.W., Dixon R.A. Variability in reaction time performance of younger and older adults. Journal of Gerontology Series B: Social Sciences 2002, 57:P101-P115.
32. Hultsch D.F., MacDonald S.W., Hunter M.A., Levy-Bencheton J., Strauss E. Intraindividual variability in cognitive performance in older adults: Comparison of adults with mild dementia, adults with arthritis, and healthy adults. Neuropsychology 2000, 14:588-598.
33. Kløve H. Grooved pegboard 1963, Lafayette Instruments, Indiana.
34. Langford T.D., Everall I.P., Masliah E. Current concepts in HIV neuropathogenesis: Neural injury, white matter disease, and neurotropic factors. The Neurology of AIDS 2005, 403-414. Oxford University Press, London. 2nd Edition. H.E. Gendelment, I. Grant, I.P. Everall, S. Lipton, S. Swindells (Eds.).
35. Larussa D., Lorenzini P., Cingolani A., Bossolasco S., Grisetti S., Bongiovanni M., Italian Registry Investigative NeuroAIDS (IRINA) Highly active antiretroviral therapy reduces the age-associated risk of dementia in a cohort of older HIV-1 infected patients. AIDS Research and Human Retroviruses 2006, 22:386-392.
36. Letendre S., Marquie-Beck J., Capparelli E., Best B., Clifford D., Collier A.C., CHARTER Group Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Archives of Neurology 2008, 65:65-70.
37. Levine A.J., Hardy D.J., Barclay T.R., Reinhard M.J., Cole M.M., Hinkin C.H. Elements of attention in HIV-infected adults: Evaluation of an existing model. Journal of Clinical and Experimental Neuropsychology 2008, 30:53-62.
38. MacDonald S.W., Hultch D.F., Dixon R.A. Performance variability is related to change in cognition: Evidence from the Victoria Longitudinal Study. Psychological Aging 2003, 18:510-523.
39. MacDonald S.W., Li S.C., Backman L. Neural underpinnings of within-person variability in cognitive functioning. Psychological Aging 2009, 24:792-808.
40. Magalhaes M.G., Greenberg B., Hansen H., Glick M. Comorbidities in older patients with HIV: A retrospective study. Journal of the American Dental Association 2007, 138:1468-1475.
41. Malaspina, L., Woods, S. P., Moore, D. J., Depp, C., Letendre, S. L., Jeste, D. HNRP Group (in press). Successful cognitive aging in persons living with HIV infection. Journal of NeuroVirology.
42. McMurtray A., Nakamoto B., Shikuma C., Valcour V. Small vessel vascular damage in human immunodeficiency virus infection: The Hawaii Aging with HIV Cohort. Cerebrovascular Disease 2007, 24:236-241.
43. McNair D.M., Lorr M., Droppleman L.F. Manual for the Profile of Mood States 1981, EdITS, San Diego.
44. Morgan E.E., Woods S.P., Weber E., Dawson M.S., Carey C.L., Moran L.M., HNRC Group HIV-associated episodic memory impairment: Evidence of a possible differential deficit in source memory for complex visual stimuli. Journal of Neuropsychiatry and Clinical Neuroscience 2009, 21:189-198.
45. Prins N.D., van Dijk E.J., den H.T., Vermeer S.E., Jolles J., Koudstall P.J., Breteler M.M. Cerebral small-vessel disease and decline in information processing speed, executive function, and memory. Brain 2005, 128:2034-2041.
46. Psychological Corporation WAIS-III and WMS-III Technical Manual 1997, Author, San Antonio, TX.
47. Psychological Corporation Wechsler Test of Adult Reading 2001, Psychological Corporation, San Antonio, TX.
48. Rapp M.A., Schnaider-Beeri M., Sano M., Silverman J.M., Haroutunian V. Cross-domain variability of cognitive performance in very old nursing home residents and community dwellers: Relationship to functional status. Gerontology 2005, 51:206-212.
49. Raskin S. Memory for Intentions Screening Test. Journal of the International Neuropsychological Society 2004, 10(Suppl. 1):110. [abstract].
50. Reger M., Welsh R., Razani J., Martin D.J., Boone K.B. A meta-analysis of the neuropsychological sequelae of HIV infection. Journal of the International Neuropsychological Society 2002, 8:410-424.
51. Reitan R.M., Wolfson D. The Halstead-Reitan Neuropsychological Test Battery: Theory and clinical interpretation 1993, Neuropsychology Press, Tucson, AZ.
52. Sacktor N., Skolasky R., Selnes O.A., Watters M., Poff P., Shiramizu B., Shikuma C., Valcour V. Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals. Journal of NeuroVirology 2007, 13:203-209.
53. Sacktor N., Skolasky R.L., Cox C., Selnes O., Becker J.T., Cohen B., Miller E.N. Multicenter AIDS Cohort Study (MACS). Longitudinal psychomotor speed performance in human immunodeficiency virus-seropositive individuals: Impact of age and serostatus. Journal of Neurovirology 2010, 16:335-341.
54. Salthouse T.A. The processing-speed theory of adult age differences in cognition. Psychological Reviews 1996, 103:403-428.
55. Schmiedek F., Lovden M., Lindenberger U. On the relation of mean reaction time and intraindividual reaction time variability. Psychological Aging 2009, 24:841-857.
56. Schretlen D.J., Munro C.A., Anthony J.C., Pearlson G.D. Examining the range of normal intraindividual variability in neuropsychological test performance. Journal of the International Neuropsychological Society 2003, 9:864-870.
57. Scott, J. C., Woods, S. P., Weber, E., Carey, C. L., Dawson, M., Bondi, M., ... & The HNRC Group (in press). Neurocognitive consequences of HIV infection in older adults: An evaluation of the " cortical" hypothesis. AIDS and Behavior.
58. Shimamura A.P., Jurica P.J. Memory interference effects and aging: Findings from a test of frontal lobe function. Neuropsychology 1994, 8:408-412.
59. Stern R.A., Javorsky D.J., Singer E.A., Harris N.G., Somerville J., Duke L.M., Kaplan E. Boston Qualitative Scoring System for the Rey-Osterreith Complex Figure (BQSS) 1999, Psychological Assessment Resources, Lutz.
60. Thames, A. D., Kim, M. S., Becker, B. W., Foley, J. M., Hines, L. J., Singer, E. J., Hinkin, C. H. (in press). Medication and finance management among HIV-infected adults: The impact of age and cognition. Journal of Clinical and Experimental Neuropsychology.
61. Valcour V., Paul R. HIV infection ad dementia in older adults. Clinical Infectious Diseases 2006, 42:1449-1454.
62. Valcour, V., Paul, R., Neuhaus, J., & Shikuma, C. (in press). The effects of age and HIV on neuropsychological performance. Journal of the International Neuropsychological Society.
63. Valcour V., Shikuma C., Shiramizu B., Watters M., Poff P., Selnes O., Sacktor N. Higher frequency of dementia in older HIV-1 individuals: The Hawaii Aging with HIV Cohort. Neurology 2004, 63:822-827.
64. Valcour V., Shikuma C., Shiramizu B., Watters M., Poff P., Selnes O., Sacktor N. Age, apolipoprotein E4, and the risk of HIV dementia: The Hawaii Aging with HIV Cohort. Journal of Neuroimmunology 2004, 157:197-2002.
65. West R., Murphy K.J., Armillo M.L., Craik F.M., Stuss D.T. Lapses of intention and performance variability reveal age-related increases in fluctuations of executive control. Brain and Cognition 2002, 49:402-419.
66. Wetter S.R., Delis D.C., Houston W.S., Jacobson M.W., Lansing A., Cobell K., Bondi M.W. Heterogeneity in verbal memory: A marker of preclinical Alzheimer's disease?. Aging, Neuropsychology, and Cognition 2006, 13:503-515.
67. Woods S.P., Moran L.M., Dawson M.S., Carey C.L., Grant I., the HIV Neurobehavioral Research Center Psychometric characteristics of the memory for intentions screening test. Clinical Neuropsychology 2008, 22:864-878.
68. Woods S.P., Scott J.C., Sires D.A., Grant I., Heaton R.K., Troster A.I., The HIV Neurobehavioral Research Center Group Action (verb) fluency: Test-retest reliability, normative standards, and construct validity. Journal of the International Neuropsychological Society 2005, 11:408-415.
69. Woods S.P., Weber E., Cameron M.V., Dawson M.S., Delano-Wood L., Bondi M., HNRP Group Spontaneous Strategy Use Protects Against Visual Working Memory Deficits in Older Adults Infected with HIV. Archives of Clinical Neuropsychology 2010, 25:724-733.
70. World Health Organization Composite International Diagnostic Interview (CIDI, version 2.1) 1998, World Health Organization, Geneva, Switzerland.