A cost-effective protocol for screening patients for methicillin-resistant Staphylococcus aureus

British Journal of Biomedical Science

Volumn 68, Issue 3, 2011, Pages 126-130

  Dickson, Elizabeth M ^a   Davidson, M M ^a   Hay, A J ^a   Ho Yen, D O ^a  

^a RAIGMORE HOSPITAL   (United Kingdom)

Author keywords

Agglutination; Latex fixation tests; Methicillin resistant Staphylococcus aureus; Penicillin binding proteins

Indexed keywords

AGAR; PENICILLIN BINDING PROTEIN;

ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC KIT; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCREENING;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

EID: 80052222356     PISSN: 09674845     EISSN: None     Source Type: Journal    
DOI: 10.1080/09674845.2011.11730339     Document Type: Article

References (31)

1. Humphreys H. Can we do better in controlling and preventing methicillin-resistant Staphylococcus aureus (MRSA) in the intensive care unit (ICU)? Eur J Clin Microbiol Infect Dis 2008; 27: 409-13.
2. Gould IM. The clinical significance of methicillin-resistant Staphylococcus aureus. J Hosp Infect 2005; 61: 277-82. (Pubitemid 43009071)
3. European Antimicrobial Resistance Surveillance System annual report. 2008. Antimicrobial Resistance in Europe. Ch 5, Subsection 5.3: Staphylococcus aureus, 55-8.
4. Department of Health. Screening for MRSA colonisation: a strategy for NHS trusts. London: NHS, 2006.
5. Rajan L, Smyth E, Humphreys H. Screening for MRSA in ICU patients. How does PCR compare with culture? J Infect 2007; 55: 353-7.
6. Aldeyab MA, Kearney MP, Hughes CM et al. Can the use of a rapid polymerase chain screening method decrease the incidence of nosocomial meticillin-resistant Staphylococcus aureus? J Hosp Infect 2009; 71: 22-8.
7. Brown DFJ, Edwards DI, Hawkey PM et al. Guidelines for the laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA). J Antimicrob Chemother 2005; 56: 1000-18. (Pubitemid 43009813)
8. Perry JD, Davies A, Butterworth LA, Hopley ALJ, Nicholson A, Gould KF. Development and evaluation of a chromogenic agar medium for methicillin- resistant Staphylococcus aureus. J Clin Microbiol 2004; 42: 4519-23. (Pubitemid 39362365)
9. Struelens MJ, Hawkey PM, French GL, Witte W, Tacconelli E. Laboratory tools and strategies for methicillin-resistant Staphylococcus aureus screening, surveillance and typing: state of the art and unmet needs. Clin Microbiol Infect 2009; 15: 112-9.
10. Hagen RM, Seegmüller I, Navai J, Kappstein I, Lehn N, Miethke T. Development of a real-time PCR assay for rapid identification of methicillin-resistant Staphylococcus aureus from clinical samples. Int J Med Microbiol 2005; 295: 77-86. (Pubitemid 40692859)
11. Nilsson P, Alexandersson H, Ripa T. Use of broth enrichment and real-time PCR to exclude the presence of methicillin-resistant Staphylococcus aureus in clinical samples: a sensitive screening approach. Clin Microbiol Infect 2005; 11: 1027-34. (Pubitemid 41748939)
12. Renwick L, Hardie A, Girvan EK et al. Detection of meticillin-resistant Staphylococcus aureus and Panton-Valentine leukocidin directly from clinical samples and the development of a multiplex assay using real-time polymerase chain reaction. Eur J Clin Microbiol Infect Dis 2008; 27: 791-6.
13. Cunningham R, Jenks P, Northwood J, Wallis M, Ferguson S, Hunt S. Effect on MRSA transmission of rapid PCR testing of patients admitted to critical care. J Hosp Infect 2007; 65: 24-8. (Pubitemid 44932976)
14. Wolk DM, Picton E, Johnson D et al. Multicenter evaluation of the Cepheid Xpert methicillin-resistant Staphylococcus aureus (MRSA) test as a rapid screening method for detection of MRSA in nares. J Clin Microbiol 2009; 47: 758-64.
15. Matsuhashi M, Song MD, Ishino F et al. Molecular cloning of the gene of a penicillin-binding protein supposed to cause high resistance to beta-lactam antibiotics in Staphylococcus aureus. J Bacteriol 1986; 167: 975-80. (Pubitemid 16045033)
16. Nakatomi Y, Sugiyama J. A rapid latex agglutination assay for the detection of penicillin-binding protein 2′. Microbiol Immunol 1998; 42: 739-43. (Pubitemid 28547596)
17. Van Leeuwen WB, Van Pelt C, Luijendijk A, Verbrugh HA, Goessens WHF. Rapid detection of methicillin resistance in Staphylococcus aureus isolates by the MRSA-Screen latex agglutination test. J Clin Microbiol 1999; 37: 3029-30. (Pubitemid 29391933)
18. Chapin KC, Musgnug MC. Evaluation of penicillin binding protein 2a latex agglutination assay for identification of methicillin-resistant Staphylococcus aureus directly from blood cultures. J Clin Microbiol 2004; 42: 1283-4. (Pubitemid 38332867)
19. Khandavilli S, Wilson P, Cookson B, Cepeda J, Bellingan G, Brown J. Utility of spa typing for investigating the local epidemiology of MRSA on a UK intensive care ward. J Hosp Infect 2009; 71: 29-35.
20. Harbarth S. Control of endemic methicillin-resistant Staphylococcus aureus - recent advances and future challenges. Clin Microbiol Infect 2006; 12: 1154-62. (Pubitemid 44762516)
21. Louie L, Soares D, Meaney H, Vearncombe M, Simor AE. Evaluation of a new chromogenic medium, MRSA Select, for detection of methicillin-resistant Staphylococcus aureus. J Clin Microbiol 2006; 44: 4561-3. (Pubitemid 44937096)
22. Carson J, Lui B, Rosmus L, Rennick H, Fuller J. Interpretation of MRSASelect screening agar at 24 hours of incubation. J Clin Microbiol 2009; 47: 566-8.
23. Nonhoff C, Denis O, Brenner A et al. Comparison of three chromogenic media and enrichment broth media for the detection of methicillin-resistant Staphylococcus aureus from mucocutaneous screening specimens. Eur J Clin Microbiol Infect Dis 2009; 28: 363-9.
24. Ibrahem S, Salmenlinna S, Virolainen A et al. Carriage of methicillin-resistant staphylococci and their SCCmec types in a long-term-care facility. J Clin Microbiol 2009; 47: 32-7.
25. Cavassini M, Wenger A, Jaton K, Bille J, Blanc DS. Authors' reply. Further evaluation of the MRSA-Screen kit for rapid detection of methicillin resistance. J Clin Microbiol 1999; 37: 3784.
26. Reilly JS, Stewart S, Christie P et al. Universal screening for meticillin-resistant Staphylococcus aureus: interim results for the NHS Scotland pathfinder project. J Hosp Infect 2010; 74: 35-41.
27. Conterno LO, Shymanski J, Ramotar K et al. Real-time polymerase chain reaction detection of methicillin-resistant Staphylococcus aureus: impact on nosocomial transmission and costs. Infect Control Hosp Epidemiol 2007; 28: 1134-41. (Pubitemid 47580455)
28. Davidson MM, Evans R, Hay AJ. Same-day detection of meticillin-resistant Staphylococcus aureus from screening swabs by real-time polymersase chain reaction. J Hosp Infect 2006; 63: 484-5.
29. Clancy M, Gaepler A, Wilson M, Douglas I, Johnson J, Price CS. Active screening in high-risk units is an effective and cost-avoidant method to reduce the rate of methicillin-resistant Staphylococcus aureus infection in the hospital. Infect Control Hosp Epidemiol 2006; 27: 1009-17. (Pubitemid 44670975)
30. Gavaldà L, Masuet C, Beltran J et al. Comparative cost of selective screening to prevent transmission of methicillin-resistant Staphylococcus aureus (MRSA), compared with the attributable costs of MRSA infection. Infect Control Hosp Epidemiol 2006; 27: 1264-6. (Pubitemid 44807476)
31. Schulz M, Nonnenmacher C, Mutters R. Cost-effectiveness of rapid MRSA screening in surgical patients. Eur J Clin Microbiol Infect Dis 2009; 28: 1291-6.