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Volumn 57, Issue 9, 2011, Pages 1263-1266

Heritability, weak effects, and rare variants in genomewide association studies

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; LOW DENSITY LIPOPROTEIN; PEPTIDASE; SORTILIN; UBIQUITIN SPECIFIC PEPTIDASE 3; UNCLASSIFIED DRUG;

EID: 80052191652     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2010.155655     Document Type: Note
Times cited : (5)

References (23)
  • 1
    • 78650134241 scopus 로고    scopus 로고
    • Multi-locus models of genetic risk of disease
    • Wray NR, Goddard ME. Multi-locus models of genetic risk of disease. Genome Med 2010;2:10.
    • (2010) Genome Med , vol.2 , pp. 10
    • Wray, N.R.1    Goddard, M.E.2
  • 2
    • 77957947562 scopus 로고    scopus 로고
    • Hundreds of variants clustered in genomic loci and biological pathways affect human height
    • Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010;467: 832-8.
    • (2010) Nature , vol.467 , pp. 832-838
    • Lango Allen, H.1    Estrada, K.2    Lettre, G.3    Berndt, S.I.4    Weedon, M.N.5    Rivadeneira, F.6
  • 5
    • 77955868822 scopus 로고    scopus 로고
    • Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry:A prospective meta-analysis from the CHARGE Consortium
    • Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, et al. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the CHARGE Consortium. Circ Cardiovasc Genet 2010;3:256-66.
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 256-266
    • Smith, N.L.1    Felix, J.F.2    Morrison, A.C.3    Demissie, S.4    Glazer, N.L.5    Loehr, L.R.6
  • 6
    • 80052186988 scopus 로고    scopus 로고
    • A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy
    • Villard E, Perret C, Gary F, Proust C, Dilanian G, Hengstenberg C, et al. A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. Eur Heart J 2011;32:1065-76.
    • (2011) Eur Heart J , vol.32 , pp. 1065-1076
    • Villard, E.1    Perret, C.2    Gary, F.3    Proust, C.4    Dilanian, G.5    Hengstenberg, C.6
  • 8
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Schunkert H, Konig IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 2011;43: 333-8.
    • (2011) Nat Genet , vol.43 , pp. 333-338
    • Schunkert, H.1    Konig, I.R.2    Kathiresan, S.3    Reilly, M.P.4    Assimes, T.L.5    Holm, H.6
  • 9
    • 79955464911 scopus 로고    scopus 로고
    • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
    • Naj AC, Jun G, Beecham GW, Wang L-S, Vardarajan BN, Buros J, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet 2011;43:436-41.
    • (2011) Nat Genet , vol.43 , pp. 436-441
    • Naj, A.C.1    Jun, G.2    Beecham, G.W.3    Wang, L.-S.4    Vardarajan, B.N.5    Buros, J.6
  • 11
    • 66249120705 scopus 로고    scopus 로고
    • The impact of newly identified loci on coronary heart disease, stroke and total mortality in the MORGAM prospective cohorts
    • Karvanen J, Silander K, Kee F, Tiret L, Salomaa V, Kuulasmaa K, et al. The impact of newly identified loci on coronary heart disease, stroke and total mortality in the MORGAM prospective cohorts. Genet Epidemiol 2009;33: 237-46.
    • (2009) Genet Epidemiol , vol.33 , pp. 237-246
    • Karvanen, J.1    Silander, K.2    Kee, F.3    Tiret, L.4    Salomaa, V.5    Kuulasmaa, K.6
  • 14
    • 78149436551 scopus 로고    scopus 로고
    • Synthetic associations in the context of genome-wide association scan signals
    • Orozco G, Barrett JC, Zeggini E. Synthetic associations in the context of genome-wide association scan signals. Hum Mol Genet 2010; 19:R137-44.
    • (2010) Hum Mol Genet , vol.19
    • Orozco, G.1    Barrett, J.C.2    Zeggini, E.3
  • 15
    • 79851487367 scopus 로고    scopus 로고
    • Synthetic associations created by rare variants do not explain most GWAS results
    • Wray NR, Purcell SM, Visscher PM. Synthetic associations created by rare variants do not explain most GWAS results. PLoS Biol 2011;9: e1000579.
    • (2011) PLoS Biol , vol.9
    • Wray, N.R.1    Purcell, S.M.2    Visscher, P.M.3
  • 16
    • 79851468862 scopus 로고    scopus 로고
    • Synthetic associations are unlikely to account for many common disease genome-wide association signals
    • Anderson CA, Soranzo N, Zeggini E, Barrett JC. Synthetic associations are unlikely to account for many common disease genome-wide association signals. PLoS Biol 2011;9:e1000580.
    • (2011) PLoS Biol , vol.9
    • Anderson, C.A.1    Soranzo, N.2    Zeggini, E.3    Barrett, J.C.4
  • 17
    • 77955070766 scopus 로고    scopus 로고
    • Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia
    • Johansen CT, Wang J, Lanktree MB, Cao H, Mc- Intyre AD, Ban MR, et al. Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet 2010; 42:684-7.
    • (2010) Nat Genet , vol.42 , pp. 684-687
    • Johansen, C.T.1    Wang, J.2    Lanktree, M.B.3    Cao, H.4    Mc- Intyre, A.D.5    Ban, M.R.6
  • 20
    • 77956327982 scopus 로고    scopus 로고
    • Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export
    • Kjolby M, Andersen OM, Breiderhoff T, Fjorback AW, Pedersen KM, Madsen P, et al. Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export. Cell Metab 2010;12:213-23.
    • (2010) Cell Metab , vol.12 , pp. 213-223
    • Kjolby, M.1    Andersen, O.M.2    Breiderhoff, T.3    Fjorback, A.W.4    Pedersen, K.M.5    Madsen, P.6
  • 22
    • 80051827842 scopus 로고    scopus 로고
    • Optimum designs for nextgeneration sequencing to discover rare variants for common complex disease
    • Epub ahead of print 2011 May 26
    • Shi G, Rao DC. Optimum designs for nextgeneration sequencing to discover rare variants for common complex disease. Genet Epidemiol [Epub ahead of print 2011 May 26].
    • Genet Epidemiol
    • Shi, G.1    Rao, D.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.