Oxidative stress mediates through apoptosis the anticancer effect of phospho-nonsteroidal anti-inflammatory drugs: Implications for the role of oxidative stress in the action of anticancer agents

Journal of Pharmacology and Experimental Therapeutics

Volumn 338, Issue 3, 2011, Pages 775-783

  Sun, Yu ^a   Huang, Liqun ^a   Mackenzie, Gerardo G ^a   Rigas, Basil ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORAMBUCIL; CREATININE; FLUOROURACIL; GLUTATHIONE; IRINOTECAN; ISOPROSTANE DERIVATIVE; MDC 43; MDC 813; MDC 917; NONSTEROID ANTIINFLAMMATORY AGENT; OXALIPLATIN; OXT 328; PACLITAXEL; PHOSPHOASPIRIN; PHOSPHOFLURBIPROFEN; PHOSPHOIBUPROFEN; PHOSPHOSULINDAC; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG; VINCRISTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL KINETICS; CELL LEVEL; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; CREATININE URINE LEVEL; DRUG MEGADOSE; DRUG POTENCY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN URINE LEVEL; TUMOR XENOGRAFT;

ANIMALS; ANNEXIN A5; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; APOPTOSIS; BROMODEOXYURIDINE; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; F2-ISOPROSTANES; FLOW CYTOMETRY; GLUTATHIONE; HUMANS; MEMBRANE POTENTIALS; MICE; MICE, NUDE; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; THIOREDOXIN-DISULFIDE REDUCTASE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80052179488     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.183533     Document Type: Article

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