GATA4 regulates ANF expression synergistically with Sp1 in a cardiac hypertrophy model

Journal of Cellular and Molecular Medicine

Volumn 15, Issue 9, 2011, Pages 1865-1877

  Hu, Xiaoqing ^a   Li, Tao ^b   Zhang, Chenguang ^a   Liu, Yinan ^a   Xu, Ming ^c,d   Wang, Weiping ^a,d   Jia, Zhuqing ^a,d   Ma, Kangtao ^a,d   Zhang, Youyi ^c,d   Zhou, Chunyan ^a,d  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b ZHEJIANG NORMAL UNIVERSITY   (China)

^c PEKING UNIVERSITY THIRD HOSPITAL   (China)

^d PEKING UNIVERSITY   (China)

Author keywords

ANF expression; Cardiac hypertrophy; GATA4; Sp1; Sp3; Transcription

Indexed keywords

ATRIAL NATRIURETIC FACTOR; PHENYLEPHRINE; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3;

ANIMAL; ARTICLE; BINDING SITE; CARDIOMEGALY; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HELA CELL; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHOSPHORYLATION; PROMOTER REGION; PROTEIN BINDING; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ATRIAL NATRIURETIC FACTOR; BASE SEQUENCE; BINDING SITES; CARDIOMEGALY; DISEASE MODELS, ANIMAL; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PHENYLEPHRINE; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC;

RATTUS;

EID: 80052166566     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01182.x     Document Type: Article

References (37)

1. Akazawa H, Komuro I. Roles of cardiac transcription factors in cardiac hypertrophy. Circ Res. 2003; 92: 1079-88.
2. Molkentin JD, Lin Q, Duncan SA, et al. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 1997; 11: 1061-72.
3. Kuo CT, Morrisey EE, Anandappa R, et al. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 1997; 11: 1048-60.
4. Liang Q, Molkentin JD. Divergent signaling pathways converge on GATA4 to regulate cardiac hypertrophic gene expression. J Mol Cell Cardiol. 2002; 34: 611-6.
5. Charron F, Tsimiklis G, Arcand M, et al. Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA. Genes Dev. 2001; 15: 2702-19.
6. Liang Q, De Windt LJ, Witt SA, et al. The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophyin vitroandin vivo. J Biol Chem. 2001; 276: 30245-53.
7. Chandrasekar B, Mummidi S, Claycomb WC, et al. Interleukin-18 is a pro-hypertrophic cytokine that acts through a phosphatidylinositol 3-kinase-phosphoinositide-dependent kinase-1-Akt-GATA4 signaling pathway in cardiomyocytes. J Biol Chem. 2005; 280: 4553-67.
8. Liang Q, Wiese RJ, Bueno OF, et al. The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes. Mol Cell Biol. 2001; 21: 7460-9.
9. Morisco C, Seta K, Hardt SE, et al. Glycogen synthase kinase 3 beta regulates GATA4 in cardiac myocytes. J Biol Chem. 2001; 276: 28586-97.
10. Tenhunen O, Sarman B, Kerkela R, et al. Mitogen-activated protein kinases p38 and ERK 1/2 mediate the wall stress-induced activation of GATA-4 binding in adult heart. J Biol Chem. 2004; 279: 24852-60.
11. Wang J, Paradis P, Aries A, et al. Convergence of protein kinase C and JAK-STAT signaling on transcription factor GATA-4. Mol Cell Biol. 2005; 25: 9829-44.
12. Yanazume T, Hasegawa K, Wada H, et al. Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy. J Biol Chem. 2002; 277: 8618-25.
13. Morimoto T, Hasegawa K, Wada H, et al. Calcineurin-GATA4 pathway is involved in beta-adrenergic agonist-responsive endothelin-1 transcription in cardiac myocytes. J Biol Chem. 2001; 276: 34983-9.
14. Kiela PR, LeSueur J, Collins JF, et al. Transcriptional regulation of the rat NHE3 gene. Functional interactions between GATA-5 and Sp family transcription factors. J Biol Chem. 2003; 278: 5659-68.
15. Suske G. The Sp-family of transcription factors. Gene. 1999; 238: 291-300.
16. Li L, He S, Sun JM, et al. Gene regulation by Sp1 and Sp3. Biochem Cell Biol. 2004; 82: 460-71.
17. Wooten LG, Ogretmen B. Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide. J Biol Chem. 2005; 280: 28867-76.
18. Fandos C, Sanchez-Feutrie M, Santalucia T, et al. GLUT1 glucose transporter gene transcription is repressed by Sp3. J Mol Biol. 1999; 294: 103-19.
19. Biesiada E, Hamamori Y, Kedes L, et al. Myogenic basic helix-loop-helix proteins and Sp1 interact as components of a multiprotein transcriptional complex required for activity of the human cardiac alpha-actin promoter. Mol Cell Biol. 1999; 19: 2577-84.
20. McDonough PM, Hanford DS, Sprenkle AB, et al. Collaborative roles for c-Jun N-terminal kinase, c-Jun, serum response factor, and Sp1 in calcium-regulated myocardial gene expression. J Biol Chem. 1997; 272: 24046-53.
21. Feldman AM, Weinberg EO, Ray PE, et al. Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. Circ Res. 1993; 73: 184-92.
22. Wang J, Xu N, Feng X, et al. Targeted disruption of Smad4 in cardiomyocytes results in cardiac hypertrophy and heart failure. Circ Res. 2005; 97: 821-8.
23. Palm-Leis A, Singh US, Herbelin BS, et al. Mitogen-activated protein kinases and mitogen-activated protein kinase phosphatases mediate the inhibitory effects of all-trans retinoic acid on the hypertrophic growth of cardiomyocytes. J Biol Chem. 2004; 279: 54905-17.
24. Liu Z, Li T, Liu Y, et al. WNT signaling promotes Nkx2.5 expression and early cardiomyogenesisviadownregulation of Hdac1. Biochim Biophys Acta. 2009; 1793: 300-11.
25. Gupta P, Huq MD, Khan SA, et al. Regulation of co-repressive activity of and HDAC recruitment to RIP140 by site-specific phosphorylation. Mol Cell Proteomics. 2005; 4: 1776-84.
26. 2+ channel and ryanodine receptor signaling in hypertrophy. PLoS Biol. 2007; 5: 0203-11.
27. Sepulveda JL, Vlahopoulos S, Iyer D, et al. Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity. J Biol Chem. 2002; 277: 25775-82.
28. Hou CH, Huang J, He QY, et al. Involvement of Sp1/Sp3 in the activation of the GATA-1 erythroid promoter in K562 cells. Cell Res. 2008; 18: 302-10.
29. Tremblay JJ, Viger RS. Transcription factor GATA-4 is activated by phosphorylation of serine 261viathe cAMP/protein kinase A signaling pathway in gonadal cells. J Biol Chem. 2003; 278: 22128-35.
30. Zakie A, Fineman JR, He Y. Sp3 inhibits Sp1-mediated activation of the cardiac troponin T promoter and is downregulated during pathological cardiac hypertrophyin vivo. Am J Physiol Heart Circ Physiol. 2006; 291: H600-11.
31. Fluck CE, Miller WL. GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1. Mol Endocrinol. 2004; 18: 1144-57.
32. Song XW, Li Q, Lin L, et al. MicroRNAs are dynamically regulated in hypertrophic hearts, and miR-199a is essential for the maintenance of cell size in cardiomyocytes. J Cell Physiol. 2010; 225: 437-43.
33. Matkovich SJ, Wang W, Tu Y, et al. MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res. 2010; 106: 166-75.
34. Callis TE, Pandya K, Seok HY, et al. MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009; 119: 2772-86.
35. Cordes KR, Srivastava D. MicroRNA regulation of cardiovascular development. Circ Res. 2009; 104: 724-32.
36. Oliveira E, Tang Y, Qian K, et al. Different microRNA in mouse heart, cardiac stem cells and cardiac stem cells with GATA4, indicate different sets of microRNA involved in stem cell differentiation by gene repression. Circulation. 2008; 118: S491.
37. Ikeda S, He A, Kong SW, et al. MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009; 29: 2193-204.