-
1
-
-
78951491924
-
Silibinin activated p53 and induced autophagic death in human fibrosarcoma HT1080 cells via reactive oxygen species-p38 and c-Jun N-terminal kinase pathways
-
Duan, W.J.; Li, Q.S.; Xia, M.Y.; Tashiro, S.; Onodera, S.; Ikejima, T. Silibinin activated p53 and induced autophagic death in human fibrosarcoma HT1080 cells via reactive oxygen species-p38 and c-Jun N-terminal kinase pathways. Biol. Pharm. Bull. 2011, 34, 47-53.
-
(2011)
Biol. Pharm. Bull
, vol.34
, pp. 47-53
-
-
Duan, W.J.1
Li, Q.S.2
Xia, M.Y.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
2
-
-
77957598340
-
Antimetastatic efficacy of Silibinin: Molecular mechanisms and therapeutic potential against cancer
-
Deep, G.; Agarwal, R. Antimetastatic efficacy of Silibinin: Molecular mechanisms and therapeutic potential against cancer. Cancer Metast. Rev. 2010, 29, 447-463.
-
(2010)
Cancer Metast. Rev
, vol.29
, pp. 447-463
-
-
Deep, G.1
Agarwal, R.2
-
3
-
-
0014294313
-
Pharmacology and toxicology of silymarin antihepatotoxic agent of Silybum marianum (L) gaertn
-
Hahn, V.G.; Lehmann, H.D.; Kürten, M.; Uebel, H.; Vogel, G. Pharmacology and toxicology of silymarin antihepatotoxic agent of Silybum marianum (L) gaertn. Arzneim.-Forsch.-Drug Res. 1968, 18, 698-704.
-
(1968)
Arzneim.-Forsch.-Drug Res
, vol.18
, pp. 698-704
-
-
Hahn, V.G.1
Lehmann, H.D.2
Kürten, M.3
Uebel, H.4
Vogel, G.5
-
4
-
-
0016433509
-
Pharmacodynamics, site and mechanism of action of silymarin, the antihepatoxic principle from Silybum mar. (L) Gaertn. 1. Acute toxicology or tolerance, general and specific (liver-) pharmacology
-
Vogel, G.; Trost, W.; Braatz, R.; Odenthal, K.P.; Brüsewitz, G.; Antweiler, H.; Seeger, R. Pharmacodynamics, site and mechanism of action of silymarin, the antihepatoxic principle from Silybum mar. (L) Gaertn. 1. Acute toxicology or tolerance, general and specific (liver-) pharmacology. Arzneim.-Forsch.-Drug Res. 1975, 25, 82-89.
-
(1975)
Arzneim.-Forsch.-Drug Res
, vol.25
, pp. 82-89
-
-
Vogel, G.1
Trost, W.2
Braatz, R.3
Odenthal, K.P.4
Brüsewitz, G.5
Antweiler, H.6
Seeger, R.7
-
5
-
-
0032008339
-
Milk thistle (Silybum marianum) for the therapy of liver disease
-
Flora, K.; Hahn, M.; Rosen, H.; Benner, K. Milk thistle (Silybum marianum) for the therapy of liver disease. Am. J. Gastroenterol. 1998, 93, 139-143.
-
(1998)
Am. J. Gastroenterol
, vol.93
, pp. 139-143
-
-
Flora, K.1
Hahn, M.2
Rosen, H.3
Benner, K.4
-
6
-
-
0034859659
-
Silymarin: A review of its clinical properties in the management of hepatic disorders
-
Wellington, K.; Jarvis, B. Silymarin: A review of its clinical properties in the management of hepatic disorders. Biodrugs 2001, 15, 465-489.
-
(2001)
Biodrugs
, vol.15
, pp. 465-489
-
-
Wellington, K.1
Jarvis, B.2
-
7
-
-
80052174795
-
Silibinin induces apoptosis by downregulating survivin through inhibition of hypoxia-inducible factor-1 alpha in non-small cell lung cancer cells
-
Kim, H.O.; Choi, H.K.; Ha, E.S.; Lee, K.J.; Hur, G.Y.; Jung, K.H.; Lee, S.Y.; Lee, S.Y.; Kim, J.H.; Shin, C.; et al. Silibinin induces apoptosis by downregulating survivin through inhibition of hypoxia-inducible factor-1 alpha in non-small cell lung cancer cells. J. Thorac. Oncol. 2010, 5, S248.
-
(2010)
J. Thorac. Oncol
, vol.5
-
-
Kim, H.O.1
Choi, H.K.2
Ha, E.S.3
Lee, K.J.4
Hur, G.Y.5
Jung, K.H.6
Lee, S.Y.7
Lee, S.Y.8
Kim, J.H.9
Shin, C.10
-
8
-
-
33750468718
-
Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: Evidence for a regulatory loop between p53 and caspase 2
-
Tyagi, A.; Singh, R.P.; Agarwal, C.; Agarwal, R. Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: Evidence for a regulatory loop between p53 and caspase 2. Carcinogenesis 2006, 27, 2269-2280.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2269-2280
-
-
Tyagi, A.1
Singh, R.P.2
Agarwal, C.3
Agarwal, R.4
-
9
-
-
0344827261
-
Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells
-
Agarwal, C.; Singh, R.P.; Dhanalakshmi, S.; Tyagi, A.K.; Tecklenburg, M.; Sclafani, R.A.; Agarwal, R. Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene 2003, 22, 8271-8282.
-
(2003)
Oncogene
, vol.22
, pp. 8271-8282
-
-
Agarwal, C.1
Singh, R.P.2
Dhanalakshmi, S.3
Tyagi, A.K.4
Tecklenburg, M.5
Sclafani, R.A.6
Agarwal, R.7
-
10
-
-
77955635233
-
Cancer Statistics, 2010
-
Jemal, A.; Siegel, R.; Xu, J.Q.; Ward, E. Cancer Statistics, 2010. CA Cancer J. Clin. 2010, 60, 277-300.
-
(2010)
CA Cancer J. Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.Q.3
Ward, E.4
-
11
-
-
33750685296
-
[6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells
-
Park, Y.J.; Wen, J.; Bang, S.; Park, S.W.; Song, S.Y. [6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells. Yonsei Med. J. 2006, 47, 688-697.
-
(2006)
Yonsei Med. J
, vol.47
, pp. 688-697
-
-
Park, Y.J.1
Wen, J.2
Bang, S.3
Park, S.W.4
Song, S.Y.5
-
12
-
-
0034057320
-
Apoptosis in cancer
-
Lowe, S.W.; Lin, A.W. Apoptosis in cancer. Carcinogenesis 2000, 21, 485-495.
-
(2000)
Carcinogenesis
, vol.21
, pp. 485-495
-
-
Lowe, S.W.1
Lin, A.W.2
-
13
-
-
0034899716
-
Shared pathways: Death receptors and cytotoxic drugs in cancer therapy
-
Petak, I.; Houghton, J.A. Shared pathways: Death receptors and cytotoxic drugs in cancer therapy. Pathol. Oncol. Res. 2001, 7, 95-106.
-
(2001)
Pathol. Oncol. Res
, vol.7
, pp. 95-106
-
-
Petak, I.1
Houghton, J.A.2
-
14
-
-
0037069929
-
Chemotherapy: Targeting the mitochondrial cell death pathway
-
Debatin, K.M.; Poncet, D.; Kroemer, G. Chemotherapy: Targeting the mitochondrial cell death pathway. Oncogene 2002, 21, 8786-8803.
-
(2002)
Oncogene
, vol.21
, pp. 8786-8803
-
-
Debatin, K.M.1
Poncet, D.2
Kroemer, G.3
-
15
-
-
20344385260
-
Targeting apoptosis Pathways in Cancer Therapy
-
Irene, M.; Thomas, E.; Alex, A. Targeting apoptosis Pathways in Cancer Therapy. CA Cancer J. Clin. 2005, 55, 178-194.
-
(2005)
CA Cancer J. Clin
, vol.55
, pp. 178-194
-
-
Irene, M.1
Thomas, E.2
Alex, A.3
-
16
-
-
4544287556
-
Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages
-
Tyagi, A.; Agarwal, C.; Harrison, G.; Glode, L.M.; Agarwal, R. Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages. Carcinogenesis 2004, 25, 1711-1720.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1711-1720
-
-
Tyagi, A.1
Agarwal, C.2
Harrison, G.3
Glode, L.M.4
Agarwal, R.5
-
17
-
-
35248818831
-
Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer
-
Hogan, F.S.; Krishnegowda, N.K.; Mikhailova, M.; Kahlenberg, M.S. Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer. J. Surg. Res. 2007, 143, 58-65.
-
(2007)
J. Surg. Res
, vol.143
, pp. 58-65
-
-
Hogan, F.S.1
Krishnegowda, N.K.2
Mikhailova, M.3
Kahlenberg, M.S.4
-
18
-
-
33244472101
-
Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: A comparison of flavanone silibinin with flavanolignan mixture silymarin
-
Deep, G.; Singh, R.P.; Agarwal, C.; Kroll, D.J.; Agarwal, R. Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: A comparison of flavanone silibinin with flavanolignan mixture silymarin. Oncogene 2006, 25, 1053-1069.
-
(2006)
Oncogene
, vol.25
, pp. 1053-1069
-
-
Deep, G.1
Singh, R.P.2
Agarwal, C.3
Kroll, D.J.4
Agarwal, R.5
-
19
-
-
77949907818
-
Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators
-
Mateen, S.; Tyagi, A.; 1, Agarwal, C.; Singh, R.P.; Agarwal, R. Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators. Mol. Carcinog. 2010, 49, 247-258.
-
(2010)
Mol. Carcinog
, vol.49
, pp. 247-258
-
-
Mateen, S.1
Tyagi, A.2
Agarwal, C.3
Singh, R.P.4
Agarwal, R.5
-
20
-
-
0344827261
-
Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells
-
Agarwal, C.; Singh, R.P.; Dhanalakshmi, S.; Tyagi, A.K.; Tecklenburg, M.; Sclafani, R.A.; Agarwal, R. Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene 2003, 22, 8271-8282.
-
(2003)
Oncogene
, vol.22
, pp. 8271-8282
-
-
Agarwal, C.1
Singh, R.P.2
Dhanalakshmi, S.3
Tyagi, A.K.4
Tecklenburg, M.5
Sclafani, R.A.6
Agarwal, R.7
-
21
-
-
53949096956
-
Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR-ERK activation in renal cell carcinoma
-
Li, L.; Gao, Y.; Zhang, L.; Zeng, J.; He, D.; Sun, Y. Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR-ERK activation in renal cell carcinoma. Cancer Lett. 2008, 272, 61-69.
-
(2008)
Cancer Lett
, vol.272
, pp. 61-69
-
-
Li, L.1
Gao, Y.2
Zhang, L.3
Zeng, J.4
He, D.5
Sun, Y.6
-
22
-
-
0346327392
-
Dual action of cyclin-dependent kinase inhibitors: Induction of cell cycle arrest and apoptosis. A comparison of the effects exerted by roscovitine and cisplatin
-
Wesierska-Gadek, J.; Gueorguieva, M.; Horky, M. Dual action of cyclin-dependent kinase inhibitors: induction of cell cycle arrest and apoptosis. A comparison of the effects exerted by roscovitine and cisplatin. Pol. J. Pharmacol. 2003, 55, 895-902.
-
(2003)
Pol. J. Pharmacol
, vol.55
, pp. 895-902
-
-
Wesierska-Gadek, J.1
Gueorguieva, M.2
Horky, M.3
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