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Volumn 118, Issue 8, 2011, Pages 2184-2190

In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINASE; CARRIER PROTEIN; DAUNORUBICIN; FORODESINE; GUANOSINE TRIPHOSPHATE; MESSENGER RNA; NELARABINE; NUCLEOSIDE; PREDNISONE; PROTEIN ENT1; PROTEIN ENT2; UNCLASSIFIED DRUG; VINCRISTINE;

EID: 80052158260     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-02-337840     Document Type: Article
Times cited : (36)

References (44)
  • 1
    • 30444437486 scopus 로고    scopus 로고
    • Treatment of acute lymphoblastic leukemia
    • Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med. 2006;354(2):166-178.
    • (2006) N Engl J Med , vol.354 , Issue.2 , pp. 166-178
    • Pui, C.H.1    Evans, W.E.2
  • 2
    • 36349018880 scopus 로고    scopus 로고
    • Pediatric acute myeloid leukemia: Towards high-quality cure of all patients
    • Kaspers GJ, Zwaan CM. Pediatric acute myeloid leukemia: towards high-quality cure of all patients. Haematologica. 2007;92(11):1519-1532.
    • (2007) Haematologica , vol.92 , Issue.11 , pp. 1519-1532
    • Kaspers, G.J.1    Zwaan, C.M.2
  • 3
    • 79952095577 scopus 로고    scopus 로고
    • Modern therapy of acute lymphoblastic leukemia
    • Bassan R, Hoelzer D. Modern therapy of acute lymphoblastic leukemia. J Clin Oncol. 2011;29(5):532-543.
    • (2011) J Clin Oncol , vol.29 , Issue.5 , pp. 532-543
    • Bassan, R.1    Hoelzer, D.2
  • 4
    • 79952086942 scopus 로고    scopus 로고
    • Therapeutic advances in acute myeloid leukemia
    • Burnett A, Wetzler M, Lowenberg B. Therapeutic advances in acute myeloid leukemia. J Clin Oncol. 2011;29(5):487-494.
    • (2011) J Clin Oncol , vol.29 , Issue.5 , pp. 487-494
    • Burnett, A.1    Wetzler, M.2    Lowenberg, B.3
  • 5
    • 0032537481 scopus 로고    scopus 로고
    • One-third-the-sites transitionstate inhibitors for purine nucleoside phosphorylase
    • Miles RW, Tyler PC, Furneaux RH, Bagdassarian CK, Schramm VL. One-third-the-sites transitionstate inhibitors for purine nucleoside phosphorylase. Biochemistry. 1998;37(24):8615-8621.
    • (1998) Biochemistry , vol.37 , Issue.24 , pp. 8615-8621
    • Miles, R.W.1    Tyler, P.C.2    Furneaux, R.H.3    Bagdassarian, C.K.4    Schramm, V.L.5
  • 6
    • 70349567556 scopus 로고    scopus 로고
    • Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM
    • Alonso R, Lopez-Guerra M, Upshaw R, et al. Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM. Blood. 2009;114(8):1563- 1575.
    • (2009) Blood , vol.114 , Issue.8 , pp. 1563-1575
    • Alonso, R.1    Lopez-Guerra, M.2    Upshaw, R.3
  • 7
    • 0038730672 scopus 로고    scopus 로고
    • Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor-BCX-1777
    • Bantia S, Ananth SL, Parker CD, Horn LL, Upshaw R. Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor-BCX-1777. Int Immunopharmacol. 2003;3(6):879-887.
    • (2003) Int Immunopharmacol , vol.3 , Issue.6 , pp. 879-887
    • Bantia, S.1    Ananth, S.L.2    Parker, C.D.3    Horn, L.L.4    Upshaw, R.5
  • 8
    • 0035836674 scopus 로고    scopus 로고
    • Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes
    • Kicska GA, Long L, Horig H, et al. Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes. Proc Natl Acad Sci U S A. 2001;98(8):4593-4598.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.8 , pp. 4593-4598
    • Kicska, G.A.1    Long, L.2    Horig, H.3
  • 9
    • 33749365341 scopus 로고    scopus 로고
    • Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells
    • Balakrishnan K, Nimmanapalli R, Ravandi F, Keating MJ, Gandhi V. Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells. Blood. 2006;108(7):2392-2398.
    • (2006) Blood , vol.108 , Issue.7 , pp. 2392-2398
    • Balakrishnan, K.1    Nimmanapalli, R.2    Ravandi, F.3    Keating, M.J.4    Gandhi, V.5
  • 10
    • 0004514220 scopus 로고
    • Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines
    • Carson DA, Kaye J, Matsumoto S, Seegmiller JE, Thompson L. Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines. Proc Natl Acad Sci U S A. 1979;76(5):2430-2433.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , Issue.5 , pp. 2430-2433
    • Carson, D.A.1    Kaye, J.2    Matsumoto, S.3    Seegmiller, J.E.4    Thompson, L.5
  • 11
    • 0017639365 scopus 로고
    • Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)
    • Carson DA, Kaye J, Seegmiller JE. Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s). Proc Natl Acad Sci U S A. 1977;74(12):5677-5681.
    • (1977) Proc Natl Acad Sci U S A , vol.74 , Issue.12 , pp. 5677-5681
    • Carson, D.A.1    Kaye, J.2    Seegmiller, J.E.3
  • 12
    • 0017807276 scopus 로고
    • Deoxyguanosine triphosphate as a possible toxic metabolite in the immunodeficiency associated with purine nucleoside phosphorylase deficiency
    • Cohen A, Gudas LJ, Ammann AJ, Staal GE, Martin DW Jr. Deoxyguanosine triphosphate as a possible toxic metabolite in the immunodeficiency associated with purine nucleoside phosphorylase deficiency. J Clin Invest. 1978;61(5):1405-1409.
    • (1978) J Clin Invest , vol.61 , Issue.5 , pp. 1405-1409
    • Cohen, A.1    Gudas, L.J.2    Ammann, A.J.3    Staal, G.E.4    Martin Jr., D.W.5
  • 13
    • 84919573117 scopus 로고
    • Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity
    • Giblett ER, Ammann AJ, Wara DW, Sandman R, Diamond LK. Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity. Lancet. 1975;1(7914):1010-1013.
    • (1975) Lancet , vol.1 , Issue.7914 , pp. 1010-1013
    • Giblett, E.R.1    Ammann, A.J.2    Wara, D.W.3    Sandman, R.4    Diamond, L.K.5
  • 14
    • 0020614859 scopus 로고
    • Selective toxicity of deoxyguanosine and arabinosyl guanine for T-leukemic cells
    • Cohen A, Lee JW, Gelfand EW. Selective toxicity of deoxyguanosine and arabinosyl guanine for T-leukemic cells. Blood. 1983;61(4):660-666.
    • (1983) Blood , vol.61 , Issue.4 , pp. 660-666
    • Cohen, A.1    Lee, J.W.2    Gelfand, E.W.3
  • 15
    • 0021933378 scopus 로고
    • Metabolic basis of arabinonucleoside selectivity for human leukemic T- and B-lymphoblasts
    • Verhoef V, Fridland A. Metabolic basis of arabinonucleoside selectivity for human leukemic T- and B-lymphoblasts. Cancer Res. 1985;45(8):3646-3650.
    • (1985) Cancer Res , vol.45 , Issue.8 , pp. 3646-3650
    • Verhoef, V.1    Fridland, A.2
  • 16
    • 0021920019 scopus 로고
    • Metabolism and selective cytotoxicity of 9-beta-D-arabinofuranosylguanine in human lymphoblasts
    • Shewach DS, Daddona PE, Ashcraft E, Mitchell BS. Metabolism and selective cytotoxicity of 9-beta-D-arabinofuranosylguanine in human lymphoblasts. Cancer Res. 1985;45(3):1008-1014.
    • (1985) Cancer Res , vol.45 , Issue.3 , pp. 1008-1014
    • Shewach, D.S.1    Daddona, P.E.2    Ashcraft, E.3    Mitchell, B.S.4
  • 17
    • 0021159928 scopus 로고
    • Specific cytotoxicity of arabinosylguanine toward cultured T lymphoblasts
    • Ullman B, Martin DW Jr. Specific cytotoxicity of arabinosylguanine toward cultured T lymphoblasts. J Clin Invest. 1984;74(3):951-955.
    • (1984) J Clin Invest , vol.74 , Issue.3 , pp. 951-955
    • Ullman, B.1    Martin Jr., D.W.2
  • 19
    • 28844495976 scopus 로고    scopus 로고
    • A proof-of- principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine)
    • Gandhi V, Kilpatrick JM, Plunkett W, et al. A proof-of- principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine). Blood. 2005;106(13):4253-4260.
    • (2005) Blood , vol.106 , Issue.13 , pp. 4253-4260
    • Gandhi, V.1    Kilpatrick, J.M.2    Plunkett, W.3
  • 20
    • 77956299127 scopus 로고    scopus 로고
    • Phase 2 and pharmacodynamic study of oral forodesine in patients with advanced, fludarabine-treated chronic lymphocytic leukemia
    • Balakrishnan K, Verma D, O'Brien S, et al. Phase 2 and pharmacodynamic study of oral forodesine in patients with advanced, fludarabine-treated chronic lymphocytic leukemia. Blood. 2010;116(6):886-892.
    • (2010) Blood , vol.116 , Issue.6 , pp. 886-892
    • Balakrishnan, K.1    Verma, D.2    O'Brien, S.3
  • 22
    • 34250003760 scopus 로고    scopus 로고
    • Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801
    • DeAngelo DJ, Yu D, Johnson JL, et al. Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801. Blood. 2007;109(12):5136-5142.
    • (2007) Blood , vol.109 , Issue.12 , pp. 5136-5142
    • DeAngelo, D.J.1    Yu, D.2    Johnson, J.L.3
  • 23
    • 20644464975 scopus 로고    scopus 로고
    • Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: A report from the Children's Oncology Group
    • Berg SL, Blaney SM, Devidas M, et al. Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group. J Clin Oncol. 2005;23(15):3376-3382.
    • (2005) J Clin Oncol , vol.23 , Issue.15 , pp. 3376-3382
    • Berg, S.L.1    Blaney, S.M.2    Devidas, M.3
  • 24
    • 20644435369 scopus 로고    scopus 로고
    • Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies
    • Kurtzberg J, Ernst TJ, Keating MJ, et al. Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies. J Clin Oncol. 2005;23(15):3396-3403.
    • (2005) J Clin Oncol , vol.23 , Issue.15 , pp. 3396-3403
    • Kurtzberg, J.1    Ernst, T.J.2    Keating, M.J.3
  • 25
    • 0037441744 scopus 로고    scopus 로고
    • Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL generearranged infant acute lymphoblastic leukemia
    • Stam RW, den Boer ML, Meijerink JP, et al. Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL generearranged infant acute lymphoblastic leukemia. Blood. 2003;101(4):1270-1276.
    • (2003) Blood , vol.101 , Issue.4 , pp. 1270-1276
    • Stam, R.W.1    Den Boer, M.L.2    Meijerink, J.P.3
  • 26
    • 0141799965 scopus 로고    scopus 로고
    • Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia
    • Den Boer ML, Harms DO, Pieters R, et al. Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia. J Clin Oncol. 2003;21(17):3262-3268.
    • (2003) J Clin Oncol , vol.21 , Issue.17 , pp. 3262-3268
    • Den Boer, M.L.1    Harms, D.O.2    Pieters, R.3
  • 27
    • 0024402491 scopus 로고
    • Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers
    • Sherman PA, Fyfe JA. Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers. Anal Biochem. 1989;180(2):222-226.
    • (1989) Anal Biochem , vol.180 , Issue.2 , pp. 222-226
    • Sherman, P.A.1    Fyfe, J.A.2
  • 28
    • 0035003174 scopus 로고    scopus 로고
    • A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR
    • Meijerink J, Mandigers C, van de Locht L, Tonnissen E, Goodsaid F, Raemaekers J. A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR. J Mol Diagn. 2001;3(2):55-61.
    • (2001) J Mol Diagn , vol.3 , Issue.2 , pp. 55-61
    • Meijerink, J.1    Mandigers, C.2    Van De Locht, L.3    Tonnissen, E.4    Goodsaid, F.5    Raemaekers, J.6
  • 29
    • 28644447388 scopus 로고    scopus 로고
    • The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia
    • Hubeek I, Stam RW, Peters GJ, et al. The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia. Br J Cancer. 2005;93(12):1388-1394.
    • (2005) Br J Cancer , vol.93 , Issue.12 , pp. 1388-1394
    • Hubeek, I.1    Stam, R.W.2    Peters, G.J.3
  • 30
    • 0036098159 scopus 로고    scopus 로고
    • Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome
    • Zwaan CM, Kaspers GJ, Pieters R, et al. Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome. Blood. 2002;99(1):245-251.
    • (2002) Blood , vol.99 , Issue.1 , pp. 245-251
    • Zwaan, C.M.1    Kaspers, G.J.2    Pieters, R.3
  • 32
    • 0035026893 scopus 로고    scopus 로고
    • Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)-a novel potent and orally active immunosuppressive agent
    • Bantia S, Miller PJ, Parker CD, et al. Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)-a novel potent and orally active immunosuppressive agent. Int Immunopharmacol. 2001;1(6):1199-1210.
    • (2001) Int Immunopharmacol , vol.1 , Issue.6 , pp. 1199-1210
    • Bantia, S.1    Miller, P.J.2    Parker, C.D.3
  • 33
    • 0024378948 scopus 로고
    • Differential metabolism of 9-beta-D-arabinofuranosylguanine in human leukemic cells
    • Shewach DS, Mitchell BS. Differential metabolism of 9-beta-D- arabinofuranosylguanine in human leukemic cells. Cancer Res. 1989;49(23): 6498-6502.
    • (1989) Cancer Res , vol.49 , Issue.23 , pp. 6498-6502
    • Shewach, D.S.1    Mitchell, B.S.2
  • 34
    • 0026762749 scopus 로고
    • Adenosine deaminase and purine nucleoside phosphorylase in childhood lymphoblastic leukemia: Relation with differentiation stage, in vitro drug resistance and clinical prognosis
    • Pieters R, Huismans DR, Loonen AH, et al. Adenosine deaminase and purine nucleoside phosphorylase in childhood lymphoblastic leukemia: relation with differentiation stage, in vitro drug resistance and clinical prognosis. Leukemia. 1992;6(5):375-380.
    • (1992) Leukemia , vol.6 , Issue.5 , pp. 375-380
    • Pieters, R.1    Huismans, D.R.2    Loonen, A.H.3
  • 35
    • 0013040873 scopus 로고    scopus 로고
    • Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562
    • Dumontet C, Fabianowska-Majewska K, Mantincic D, et al. Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562. Br J Haematol. 1999;106(1):78-85.
    • (1999) Br J Haematol , vol.106 , Issue.1 , pp. 78-85
    • Dumontet, C.1    Fabianowska-Majewska, K.2    Mantincic, D.3
  • 36
    • 0030221526 scopus 로고    scopus 로고
    • Deoxycytidine kinase mRNA levels in leukemia cells with competitive polymerase chain reaction assay
    • Kawasaki H, Shindou K, Higashigawa M, et al. Deoxycytidine kinase mRNA levels in leukemia cells with competitive polymerase chain reaction assay. Leuk Res. 1996;20(8):677-682.
    • (1996) Leuk Res , vol.20 , Issue.8 , pp. 677-682
    • Kawasaki, H.1    Shindou, K.2    Higashigawa, M.3
  • 37
    • 0026637308 scopus 로고
    • Resistance to 1-beta-D-arabinofuranosylcytosine in human T-lymphoblasts mediated by mutations within the deoxycytidine kinase gene
    • Owens JK, Shewach DS, Ullman B, Mitchell BS. Resistance to 1-beta-D-arabinofuranosylcytosine in human T-lymphoblasts mediated by mutations within the deoxycytidine kinase gene. Cancer Res. 1992;52(9):2389-2393.
    • (1992) Cancer Res , vol.52 , Issue.9 , pp. 2389-2393
    • Owens, J.K.1    Shewach, D.S.2    Ullman, B.3    Mitchell, B.S.4
  • 38
    • 0027327388 scopus 로고
    • Role of deoxycytidine kinase in an in vitro model for AraC- and DAC-resistance: Substrate-enzyme interactions with deoxycytidine, 1-beta-D-arabinofuranosylcytosine and 5-aza-2′-deoxycytidine
    • Stegmann AP, Honders MW, Kester MG, Landegent JE, Willemze R. Role of deoxycytidine kinase in an in vitro model for AraC- and DAC-resistance: substrate-enzyme interactions with deoxycytidine, 1-beta-D- arabinofuranosylcytosine and 5-aza-2′-deoxycytidine. Leukemia. 1993;7(7):1005-1011.
    • (1993) Leukemia , vol.7 , Issue.7 , pp. 1005-1011
    • Stegmann, A.P.1    Honders, M.W.2    Kester, M.G.3    Landegent, J.E.4    Willemze, R.5
  • 39
    • 0032409839 scopus 로고    scopus 로고
    • Expression of deoxycytidine kinase (dCK) gene in leukemic cells in childhood: Decreased expression of dCK gene in relapsed leukemia
    • Kakihara T, Fukuda T, Tanaka A, et al. Expression of deoxycytidine kinase (dCK) gene in leukemic cells in childhood: decreased expression of dCK gene in relapsed leukemia. Leuk Lymphoma. 1998;31(3-4):405-409.
    • (1998) Leuk Lymphoma , vol.31 , Issue.3-4 , pp. 405-409
    • Kakihara, T.1    Fukuda, T.2    Tanaka, A.3
  • 40
    • 0030858503 scopus 로고    scopus 로고
    • Deoxycytidine kinase mRNA expression in childhood acute lymphoblastic leukemia
    • Stammler G, Zintl F, Sauerbrey A, Volm M. Deoxycytidine kinase mRNA expression in childhood acute lymphoblastic leukemia. Anticancer Drugs. 1997;8(5):517-521.
    • (1997) Anticancer Drugs , vol.8 , Issue.5 , pp. 517-521
    • Stammler, G.1    Zintl, F.2    Sauerbrey, A.3    Volm, M.4
  • 41
    • 0036606777 scopus 로고    scopus 로고
    • Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase
    • Rodriguez CO Jr, Mitchell BS, Ayres M, Eriksson S, Gandhi V. Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. Cancer Res. 2002;62(11):3100-3105.
    • (2002) Cancer Res , vol.62 , Issue.11 , pp. 3100-3105
    • Rodriguez Jr., C.O.1    Mitchell, B.S.2    Ayres, M.3    Eriksson, S.4    Gandhi, V.5
  • 42
    • 0023115207 scopus 로고
    • Membrane transport influences the rate of accumulation of cytosine arabinoside in human leukemia cells
    • White JC, Rathmell JP, Capizzi RL. Membrane transport influences the rate of accumulation of cytosine arabinoside in human leukemia cells. J Clin Invest. 1987;79(2):380-387.
    • (1987) J Clin Invest , vol.79 , Issue.2 , pp. 380-387
    • White, J.C.1    Rathmell, J.P.2    Capizzi, R.L.3
  • 43
    • 42749084016 scopus 로고    scopus 로고
    • Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H
    • Huang M, Wang Y, Gu J, et al. Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H. Leuk Res. 2008;32(8):1268-1278.
    • (2008) Leuk Res , vol.32 , Issue.8 , pp. 1268-1278
    • Huang, M.1    Wang, Y.2    Gu, J.3
  • 44
    • 77956307784 scopus 로고    scopus 로고
    • Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells
    • Balakrishnan K, Burger JA, Quiroga MP, et al. Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells. Blood. 2010;116(7):1083-1091.
    • (2010) Blood , vol.116 , Issue.7 , pp. 1083-1091
    • Balakrishnan, K.1    Burger, J.A.2    Quiroga, M.P.3


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