Myocardial oxygen consumption change predicts left ventricular relaxation improvement in obese humans after weight loss

Obesity

Volumn 19, Issue 9, 2011, Pages 1804-1812

  Lin, C Huie ^a   Kurup, Suraj ^a   Herrero, Pilar ^b   Schechtman, Kenneth B ^a   Eagon, J Christopher ^a   Klein, Samuel ^a   Dávila Román, Víctor G ^a   Stein, Richard I ^a   Dorn Ii, Gerald W ^a   Gropler, Robert J ^b   Waggoner, Alan D ^a   Peterson, Linda R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROCHLOROTHIAZIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METFORMIN; SULFONYLUREA DERIVATIVE; TRIACYLGLYCEROL;

ADULT; ARTICLE; BLOOD FLOW; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DIABETES MELLITUS; DIET THERAPY; ECHOCARDIOGRAPHY; ESTERIFICATION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FEMALE; HEART FUNCTION; HEART LEFT VENTRICLE RELAXATION; HEART MUSCLE METABOLISM; HEART MUSCLE OXYGEN CONSUMPTION; HUMAN; HYPERTENSION; INSULIN RESISTANCE; MALE; OBESITY; PHLEBOTOMY; POSITRON EMISSION TOMOGRAPHY; PROSPECTIVE STUDY; SLEEP APNEA SYNDROME; STOMACH BYPASS; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION;

ADULT; BODY MASS INDEX; COMBINED MODALITY THERAPY; DIET, REDUCING; ECHOCARDIOGRAPHY, DOPPLER; FEMALE; GASTRIC BYPASS; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; MUSCLE RELAXATION; MYOCARDIUM; OBESITY; OBESITY, MORBID; OXYGEN CONSUMPTION; POSITRON-EMISSION TOMOGRAPHY; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT; WEIGHT LOSS;

EID: 80052154999     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.186     Document Type: Article

References (36)

1. Kenchaiah S, Evans JC, Levy D et al. Obesity and the risk of heart failure. N Engl J Med 2002;347:305-313. (Pubitemid 34815352)
2. Wong CY, O'Moore-Sullivan T, Leano R et al. Alterations of left ventricular myocardial characteristics associated with obesity. Circulation 2004;110:3081-3087. (Pubitemid 39492002)
3. Banerjee S, Peterson LR. Myocardial metabolism and cardiac performance in obesity and insulin resistance. Curr Cardiol Rep 2007;9:143-149. (Pubitemid 46681116)
4. Peterson LR, Herrero P, Schechtman KB et al. Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women. Circulation 2004;109:2191-2196. (Pubitemid 38625396)
5. Cook SA, Varela-Carver A, Mongillo M et al. Abnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction. Eur Heart J 2010;31:100-111.
6. Zhou YT, Grayburn P, Karim A et al. Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci USA 2000;97:1784-1789. (Pubitemid 30118520)
7. Listenberger LL, Ory DS, Schaffer JE. Palmitate-induced apoptosis can occur through a ceramide-independent pathway. J Biol Chem 2001;276:14890-14895.
8. Aasum E, Hafstad AD, Severson DL, Larsen TS. Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice. Diabetes 2003;52:434-441. (Pubitemid 36173200)
9. Vincent HK, Powers SK, Dirks AJ, Scarpace PJ. Mechanism for obesityinduced increase in myocardial lipid peroxidation. Int J Obes Relat Metab Disord 2001;25:378-388. (Pubitemid 32209814)
10. Abdul-Ghani MA, Muller FL, Liu Y et al. Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance. Am J Physiol Endocrinol Metab 2008;295:E678-E685.
11. Vincent HK, Innes KE, Vincent KR. Oxidative stress and potential interventions to reduce oxidative stress in overweight and obesity. Diabetes Obes Metab 2007;9:813-839. (Pubitemid 47555204)
12. Leichman JG, Wilson EB, Scarborough T et al. Dramatic reversal of derangements in muscle metabolism and left ventricular function after bariatric surgery. Am J Med 2008;121:966-973.
13. Wong CY, Byrne NM, O'Moore-Sullivan T et al. Effect of weight loss due to lifestyle intervention on subclinical cardiovascular dysfunction in obesity (body mass index 〉30 kg/m2). Am J Cardiol 2006;98:1593-1598. (Pubitemid 44827966)
14. de las Fuentes L, Waggoner AD, Mohammed BS et al. Effect of moderate diet-induced weight loss and weight regain on cardiovascular structure and function. J Am Coll Cardiol 2009;54:2376-2381.
15. Viljanen AP, Karmi A, Borra R et al. Effect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults. Am J Cardiol 2009;103:1721-1726.
16. Hammer S, Snel M, Lamb HJ et al. Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function. J Am Coll Cardiol 2008;52: 1006-1012.
17. Kates AM, Herrero P, Dence C et al. Impact of aging on substrate metabolism by the human heart. J Am Coll Cardiol 2003;41:293-299. (Pubitemid 36092200)
18. Sjöström L, Narbro K, Sjöström CD et al.; Swedish Obese Subjects Study. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 2007;357:741-752. (Pubitemid 47295641)
19. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults-The Evidence Report. National Institutes of Health. Obes Res 1998;6 (Suppl 2):51S-209S.
20. Herrero P, Markham J, Bergmann SR. Quantitation of myocardial blood flow with H2 15O and positron emission tomography: assessment and error analysis of a mathematical approach. J Comput Assist Tomogr 1989;13:862-873. (Pubitemid 19245083)
21. Buck A, Wolpers HG, Hutchins GD et al. Effect of carbon-11-acetate recirculation on estimates of myocardial oxygen consumption by PET. J Nucl Med 1991;32:1950-1957.
22. Bergmann SR, Weinheimer CJ, Markham J, Herrero P. Quantitation of myocardial fatty acid metabolism using PET. J Nucl Med 1996;37: 1723-1730. (Pubitemid 26337187)
23. Matthews DR, Hosker JP, Rudenski AS et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28: 412-419. (Pubitemid 15018832)
24. Peterson LR, Waggoner AD, Schechtman KB et al. Alterations in left ventricular structure and function in young healthy obese women: assessment by echocardiography and tissue Doppler imaging. J Am Coll Cardiol 2004;43:1399-1404. (Pubitemid 38496345)
25. Dokainish H, Gonzalez R, Hartley WB et al. Usefulness of B-type natriuretic peptide levels to predict left ventricular filling pressures in patients with body mass index 〉35, 31 to 35, and 〈 or =30 kg/m2. Am J Cardiol 2007;100:1166-1171. (Pubitemid 47404472)
26. Peterson LR, Soto PF, Herrero P et al. Sex differences in myocardial oxygen and glucose metabolism. J Nucl Cardiol 2007;14:573-581. (Pubitemid 47163554)
27. Peterson LR, Soto PF, Herrero P et al. Impact of gender on the myocardial metabolic response to obesity. JACC Cardiovasc Imaging 2008;1:424-433. (Pubitemid 351998685)
28. Carey DG, Pliego GJ, Raymond RL, Skau KB. Body composition and metabolic changes following bariatric surgery: effects on fat mass, lean mass and basal metabolic rate. Obes Surg 2006;16:469-477.
29. Vik-Mo H, Mjøs OD. Influence of free fatty acids on myocardial oxygen consumption and ischemic injury. Am J Cardiol 1981;48:361-365. (Pubitemid 11019075)
30. Taegtmeyer H, Overturf ML. Effects of moderate hypertension on cardiac function and metabolism in the rabbit. Hypertension 1988;11:416-426.
31. Taegtmeyer H. Genetics of energetics: transcriptional responses in cardiac metabolism. Ann Biomed Eng 2000;28:871-876. (Pubitemid 32085371)
32. Willens HJ, Chakko SC, Byers P et al. Effects of weight loss after gastric bypass on right and left ventricular function assessed by tissue Doppler imaging. Am J Cardiol 2005;95:1521-1524. (Pubitemid 40824786)
33. Sawyer DB, Colucci WS. Mitochondrial oxidative stress in heart failure: "oxygen wastage" revisited. Circ Res 2000;86:119-120. (Pubitemid 30086169)
34. Vettor R, Mingrone G, Manco M et al. Reduced expression of uncoupling proteins-2 and-3 in adipose tissue in post-obese patients submitted to biliopancreatic diversion. Eur J Endocrinol 2003;148:543-550. (Pubitemid 36622162)
35. Baliga RR, Young JB. "Stiff central arteries" syndrome: does a weak heart really stiff the kidney? Heart Fail Clin 2008;4:ix-xii.
36. Santry HP, Gillen DL, Lauderdale DS. Trends in bariatric surgical procedures. JAMA 2005;294:1909-1917. (Pubitemid 41464692)