Towards the development of novel Trypanosoma brucei RNA editing ligase 1 inhibitors

BMC Pharmacology

Volumn 11, Issue 1, 2011, Pages

  Durrant, Jacob D ^a   McCammon, J Andrew ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGASE; NAPHTHALENE; RNA EDITING LIGASE 1; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; ENZYME INHIBITOR; MITOCHONDRIAL PROTEIN; REL1 RNA LIGASE, TRYPANOSOMA BRUCEI;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; EVOLUTIONARY ALGORITHM; HYDROGEN BOND; NONHUMAN; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN MODIFICATION; RNA EDITING; SOFTWARE; STATIC ELECTRICITY; TRYPANOSOMA BRUCEI; AFRICAN TRYPANOSOMIASIS; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER PROGRAM; DRUG ANTAGONISM; DRUG DESIGN; DRUG DEVELOPMENT; DRUG EFFECT; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; METHODOLOGY; PARASITOLOGY; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CARBON-OXYGEN LIGASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; DRUG DISCOVERY; ENZYME INHIBITORS; HUMANS; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA EDITING; SOFTWARE; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

EID: 80052112069     PISSN: None     EISSN: 14712210     Source Type: Journal    
DOI: 10.1186/1471-2210-11-9     Document Type: Article

References (14)

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