-
1
-
-
1842455329
-
Genetics of inflammatory bowel disease: Progress and prospects
-
C.G. Mathew, and C.M. Lewis Genetics of inflammatory bowel disease: progress and prospects Hum Mol Genet 13 2004 R161 R168
-
(2004)
Hum Mol Genet
, vol.13
-
-
Mathew, C.G.1
Lewis, C.M.2
-
2
-
-
2442563304
-
Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences
-
DOI 10.1053/j.gastro.2004.01.063
-
E.V. Loftus Jr Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences Gastroenterology 126 2004 1504 1517 (Pubitemid 38649869)
-
(2004)
Gastroenterology
, vol.126
, Issue.6
, pp. 1504-1517
-
-
Loftus Jr., E.V.1
-
5
-
-
70449724721
-
Genetics of inflammatory bowel disease: Implications for disease pathogenesis and natural history
-
C.W. Lees, and J. Satsangi Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history Exp Rev Gastroenterol Hepatol 3 2009 513 534
-
(2009)
Exp Rev Gastroenterol Hepatol
, vol.3
, pp. 513-534
-
-
Lees, C.W.1
Satsangi, J.2
-
6
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
A. Franke, D.P.B. McGovern, and J.C. Barrett Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci Nat Genet 42 2010 1118 1125
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.B.2
Barrett, J.C.3
-
7
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
C.A. Anderson, G. Boucher, and C.W. Lees Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 Nat Genet 43 2011 246 252
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
-
8
-
-
70649103789
-
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
-
J.C. Barrett, J.C. Lee, and C.W. Lees Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region Nat Genet 41 2009 1330 1334
-
(2009)
Nat Genet
, vol.41
, pp. 1330-1334
-
-
Barrett, J.C.1
Lee, J.C.2
Lees, C.W.3
-
9
-
-
0037379915
-
TNF-α and IFN-γ regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells
-
DOI 10.1053/gast.2003.50157
-
P. Rosenstiel, M. Fantini, and K. Brautigam TNF-[alpha] and IFN-[gamma] regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells Gastroenterology 124 2003 1001 1009 (Pubitemid 36389803)
-
(2003)
Gastroenterology
, vol.124
, Issue.4
, pp. 1001-1009
-
-
Rosenstiel, P.1
Fantini, M.2
Brautigam, K.3
Kuhbacher, T.4
Waetzig, G.H.5
Seegert, D.6
Schreiber, S.7
-
10
-
-
20844454920
-
Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release
-
M.G. Netea, G. Ferwerda, and D.J. de Jong Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release J Immunol 174 2005 6518 6523 (Pubitemid 40663847)
-
(2005)
Journal of Immunology
, vol.174
, Issue.10
, pp. 6518-6523
-
-
Netea, M.G.1
Ferwerda, G.2
De Jong, D.J.3
Jansen, T.4
Jacobs, L.5
Kramer, M.6
Naber, T.H.J.7
Drenth, J.P.H.8
Girardin, S.E.9
Kullberg, B.J.10
Adema, G.J.11
Van Der Meer, J.W.M.12
-
11
-
-
0037380969
-
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
-
DOI 10.1053/gast.2003.50153
-
T. Hisamatsu, M. Suzuki, and H.C. Reinecker CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells Gastroenterology 124 2003 993 1000 (Pubitemid 36389802)
-
(2003)
Gastroenterology
, vol.124
, Issue.4
, pp. 993-1000
-
-
Hisamatsu, T.1
Suzuki, M.2
Reinecker, H.-C.3
Nadeau, W.J.4
McCormick, B.A.5
Podolsky, D.K.6
-
12
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal α-defensin expression
-
DOI 10.1136/gut.2003.032805
-
J. Wehkamp, J. Harder, and M. Weichenthal NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression Gut 53 2004 1658 1664 (Pubitemid 39434112)
-
(2004)
Gut
, vol.53
, Issue.11
, pp. 1658-1664
-
-
Wehkamp, J.1
Harder, J.2
Weichenthal, M.3
Schwab, M.4
Schaffeler, E.5
Schlee, M.6
Herrlinger, K.R.7
Stallmach, A.8
Noack, F.9
Fritz, P.10
Schroder, J.M.11
Bevins, C.L.12
Fellermann, K.13
Stange, E.F.14
-
13
-
-
33644849605
-
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2
-
DOI 10.1074/jbc.M511044200
-
E. Voss, J. Wehkamp, and K. Wehkamp NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2 J Biol Chem 281 2006 2005 2011 (Pubitemid 43845788)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.4
, pp. 2005-2011
-
-
Voss, E.1
Wehkamp, J.2
Wehkamp, K.3
Stange, E.F.4
Schroder, J.M.5
Harder, J.6
-
14
-
-
0024406857
-
A novel genetic system to detect protein-protein interactions
-
DOI 10.1038/340245a0
-
S. Fields, and O. Song A novel genetic system to detect protein-protein interactions Nature 340 1989 245 246 (Pubitemid 19171591)
-
(1989)
Nature
, vol.340
, Issue.6230
, pp. 245-246
-
-
Fields, S.1
Song, O.-K.2
-
15
-
-
0037766786
-
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: Regulation and loss of interaction with mutation
-
DOI 10.1093/hmg/ddg162
-
J.A. Morris, G. Kandpal, and L. Ma DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation Hum Mol Genet 12 2003 1591 1608 (Pubitemid 36857306)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.13
, pp. 1591-1608
-
-
Morris, J.A.1
Kandpal, G.2
Ma, L.3
Austin, C.P.4
-
16
-
-
28844448136
-
A role for Erbin in the regulation of Nod2-dependent NF-κB signaling
-
DOI 10.1074/jbc.M508538200
-
C. McDonald, F.F. Chen, and V. Ollendorff A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling J Biol Chem 280 2005 40301 40309 (Pubitemid 41779167)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.48
, pp. 40301-40309
-
-
McDonald, C.1
Chen, F.F.2
Ollendorff, V.3
Ogura, Y.4
Marchetto, S.5
Lecine, P.6
Borg, J.-P.7
Nunez, G.8
-
17
-
-
2942535858
-
Reciprocal cross-talk between Nod2 and TAK1 signaling pathways
-
DOI 10.1074/jbc.M400682200
-
C.M. Chen, Y. Gong, and M. Zhang Reciprocal cross-talk between Nod2 and TAK1 signaling pathways J Biol Chem 279 2004 25876 25882 (Pubitemid 38756853)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.24
, pp. 25876-25882
-
-
Chen, C.-M.1
Gong, Y.2
Zhang, M.3
Chen, J.-J.4
-
18
-
-
20444486755
-
GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells
-
DOI 10.1074/jbc.M413776200
-
N. Barnich, T. Hisamatsu, and J.E. Aguirre GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells J Biol Chem 280 2005 19021 19026 (Pubitemid 41379607)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.19
, pp. 19021-19026
-
-
Barnich, N.1
Hisamatsu, T.2
Aguirre, J.E.3
Xavier, R.4
Reinecker, H.-C.5
Podolsky, D.K.6
-
19
-
-
33845975666
-
Centaurin β1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-κB activation
-
DOI 10.1074/jbc.M602383200
-
J.K. Yamamoto-Furusho, N. Barnich, and R. Xavier Centaurin beta-1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation J Biol Chem 281 2006 36060 36070 (Pubitemid 46041339)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.47
, pp. 36060-36070
-
-
Yamamoto-Furusho, J.K.1
Barnich, N.2
Xavier, R.3
Hisamatsu, T.4
Podolsky, D.K.5
-
20
-
-
0027250250
-
Mammalian ras interacts directly with the serine/threonine kinase Raf
-
DOI 10.1016/0092-8674(93)90307-C
-
A.B. Vojtek, S.M. Hollenberg, and J.A. Cooper Mammalian Ras interacts directly with the serine/threonine kinase Raf Cell 74 1993 205 214 (Pubitemid 23219891)
-
(1993)
Cell
, vol.74
, Issue.1
, pp. 205-214
-
-
Vojtek, A.B.1
Hollenberg, S.M.2
Cooper, J.A.3
-
21
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a working party of the 2005 Montreal World Congress of Gastroenterology
-
M.S. Silverberg, J. Satsangi, and T. Ahmad Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a working party of the 2005 Montreal World Congress of Gastroenterology Can J Gastroenterol 19 Suppl A 2005 5 36
-
(2005)
Can J Gastroenterol
, vol.19
, Issue.SUPPL. A
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
-
22
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
S.A. Miller, D.D. Dykes, and H.F. Polesky A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res 16 1988 1215
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
23
-
-
52649097493
-
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis
-
C.L. Noble, A.R. Abbas, and J. Cornelius Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis Gut 57 2008 1398 1405
-
(2008)
Gut
, vol.57
, pp. 1398-1405
-
-
Noble, C.L.1
Abbas, A.R.2
Cornelius, J.3
-
24
-
-
58449134949
-
Tests for gene-environment interaction from case-control data: A novel study of type i error, power and designs
-
B. Mukherjee, J. Ahn, and S.B. Gruber Tests for gene-environment interaction from case-control data: a novel study of type I error, power and designs Genet Epidemiol 32 2008 615 626
-
(2008)
Genet Epidemiol
, vol.32
, pp. 615-626
-
-
Mukherjee, B.1
Ahn, J.2
Gruber, S.B.3
-
25
-
-
4344671141
-
NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: Evidence for genetic heterogeneity within Europe?
-
DOI 10.1038/sj.gene.6364111
-
I.D.R. Arnott, E.R. Nimmo, and H.E. Drummond NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe? Genes Immun 5 2004 417 425 (Pubitemid 39139770)
-
(2004)
Genes and Immunity
, vol.5
, Issue.5
, pp. 417-425
-
-
Arnott, I.D.R.1
Nimmo, E.R.2
Drummond, H.E.3
Fennell, J.4
Smith, B.R.K.5
MacKinlay, E.6
Morecroft, J.7
Anderson, N.8
Kelleher, D.9
O'Sullivan, M.10
McManus, R.11
Satsangi, J.12
-
26
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
J.C. Barrett, S. Hansoul, and D.L. Nicolae Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Nat Genet 40 2008 955 962
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
27
-
-
77951454833
-
The Groucho/TLE/Grg family of transcriptional co-repressors
-
B.H. Jennings, and D. Ish-Horowicz The Groucho/TLE/Grg family of transcriptional co-repressors Genome Biol 9 2008 205
-
(2008)
Genome Biol
, vol.9
, pp. 205
-
-
Jennings, B.H.1
Ish-Horowicz, D.2
-
28
-
-
58249091528
-
The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors
-
C. Desjobert, P. Noy, and T. Swingler The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors Biochem J 417 2009 121 132
-
(2009)
Biochem J
, vol.417
, pp. 121-132
-
-
Desjobert, C.1
Noy, P.2
Swingler, T.3
-
29
-
-
67650255063
-
Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
-
D.P.B. McGovern, J.I. Rotter, and L. Mei Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease Inflamm Bowel Dis 15 2009 883 889
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 883-889
-
-
McGovern, D.P.B.1
Rotter, J.I.2
Mei, L.3
-
30
-
-
77950298959
-
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
-
D.P.B. McGovern, A. Gardet, and L. Torkvist Genome-wide association identifies multiple ulcerative colitis susceptibility loci Nat Genet 42 2010 332 337
-
(2010)
Nat Genet
, vol.42
, pp. 332-337
-
-
McGovern, D.P.B.1
Gardet, A.2
Torkvist, L.3
-
33
-
-
63449140634
-
The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways
-
L. Mattera, F. Escaffit, and M.J. Pillaire The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways Oncogene 28 2009 1506 1517
-
(2009)
Oncogene
, vol.28
, pp. 1506-1517
-
-
Mattera, L.1
Escaffit, F.2
Pillaire, M.J.3
-
34
-
-
0022648047
-
Differential diagnosis of Crohn's disease of the colon from ulcerative colitis: Ultrastructure study with the scanning electron microscope
-
Trabucchi, S. Mukenge, and C. Baratti Differential diagnosis of Crohn's disease of the colon from ulcerative colitis: ultrastructure study with the scanning electron microscope Int J Tissue React 8 2011 79 84
-
(2011)
Int J Tissue React
, vol.8
, pp. 79-84
-
-
Trabucchi1
Mukenge, S.2
Baratti, C.3
-
35
-
-
27744556965
-
Cellular integrity plus: Organelle-related and protein-targeting functions of intermediate filaments
-
DOI 10.1016/j.tcb.2005.09.004, PII S096289240500228X
-
D.M. Toivola, G.Z. Tao, and A. Habtezion Cellular integrity plus: organelle-related and protein-targeting functions of intermediate filaments Trends Cell Biol 15 2005 608 617 (Pubitemid 41619425)
-
(2005)
Trends in Cell Biology
, vol.15
, Issue.11
, pp. 608-617
-
-
Toivola, D.M.1
Tao, G.-Z.2
Habtezion, A.3
Liao, J.4
Omary, M.B.5
-
36
-
-
9444239263
-
The endo-lysosomal sorting machinery interacts with the intermediate filament cytoskeleton
-
DOI 10.1091/mbc.E04-03-0272
-
M.L. Styers, G. Salazar, and R. Love The endo-lysosomal sorting machinery interacts with the intermediate filament cytoskeleton Mol Biol Cell 15 2004 5369 5382 (Pubitemid 39564731)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.12
, pp. 5369-5382
-
-
Styers, M.L.1
Salazar, G.2
Love, R.3
Peden, A.A.4
Kowalczyk, A.P.5
Faundez, V.6
-
37
-
-
0022904836
-
Intracellular protein catabolism: Evidence for sequestration of proteins into an intermediate-filament fraction before lysosomal degradation
-
R.J. Mayer, M.J. Gaskell, and R. Earl Intracellular protein catabolism: evidence for sequestration of proteins into an intermediate-filament fraction before lysosomal degradation Biomed Biochem Acta 45 1986 1591 1602 (Pubitemid 17018593)
-
(1986)
Biomedica Biochimica Acta
, vol.45
, Issue.11-12
, pp. 1591-1602
-
-
Mayer, R.J.1
Gaskell, M.J.2
Earl, R.3
-
38
-
-
0023123336
-
A putative protein-sequestration site involving intermediate filaments for protein degradation by autophagy. Studies with transplanted Sendai-viral envelope proteins in HTC cells
-
R. Earl, H.E. Mangiapane, and E.E. Billett A putative protein-sequestration site involving intermediate filaments for protein degradation by autophagy Studies with transplanted Sendai-viral envelope proteins in HTC cells Biochem J 241 1987 809 815 (Pubitemid 17000734)
-
(1987)
Biochemical Journal
, vol.241
, Issue.3
, pp. 809-815
-
-
Earl, R.T.1
Mangiapane, E.H.2
Billett, E.E.3
Mayer, R.J.4
-
39
-
-
28844448136
-
A role for Erbin in the regulation of Nod2-dependent NF-κB signaling
-
DOI 10.1074/jbc.M508538200
-
C. McDonald, F.F. Chen, and V. Ollendorff A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling J Biol Chem 280 2005 40301 40309 (Pubitemid 41779167)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.48
, pp. 40301-40309
-
-
McDonald, C.1
Chen, F.F.2
Ollendorff, V.3
Ogura, Y.4
Marchetto, S.5
Lecine, P.6
Borg, J.-P.7
Nunez, G.8
-
40
-
-
20444486755
-
GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells
-
DOI 10.1074/jbc.M413776200
-
N. Barnich, T. Hisamatsu, and J.E. Aguirre GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells J Biol Chem 280 2005 19021 19026 (Pubitemid 41379607)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.19
, pp. 19021-19026
-
-
Barnich, N.1
Hisamatsu, T.2
Aguirre, J.E.3
Xavier, R.4
Reinecker, H.-C.5
Podolsky, D.K.6
|