Treatment effects of rhBMP-2 on invasiveness of oral carcinoma cell lines

Laryngoscope

Volumn 121, Issue 9, 2011, Pages 1876-1880

  Kokorina, Natalia A ^a,d   Zakharkin, Stanislav O ^b   Krebsbach, Paul H ^c   Nussenbaum, Brian ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Technology and Innovation ^*  (United States)

^c UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^d UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

Author keywords

Bone morphogenetic protein; oral cancer; squamous cell carcinoma

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; MATRIGEL; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ARTICLE; CANCER INVASION; DRUG EFFECT; GENE EXPRESSION; GENOTYPE; HUMAN; HUMAN CELL; METASTASIS; MOUTH CARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TREATMENT RESPONSE;

BONE MORPHOGENETIC PROTEIN 2; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOUTH NEOPLASMS; NEOPLASM INVASIVENESS; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 80052089419     PISSN: 0023852X     EISSN: 15314995     Source Type: Journal    
DOI: 10.1002/lary.21914     Document Type: Article

References (26)

1. Chin M, Ng T, Tom WK, et al. Repair of alveolar clefts with recombinant human bone morphogenetic protein (rhBMP-2) in patients with clefts. J Craniofac Surg 2005; 16: 778-789. (Pubitemid 41428923)
2. Herford AS, Boyne PJ,. Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (BMP-2). J Oral Maxillofac Surg 2008; 66: 616-624. (Pubitemid 351381799)
3. Nussenbaum B, Krebsbach PH,. The role of gene therapy for craniofacial and dental tissue engineering. Adv Drug Deliv Rev 2006; 58: 577-591. (Pubitemid 43928173)
4. Gao Q, Tong W, Luria JS, Wang Z, Nussenbaum B, Krebsbach PH,. Effects of bone morphogenetic protein-2 on proliferation and angiogenesis in oral squamous cell carcinoma. Int J Oral Maxillofac Surg 2010; 39: 266-271.
5. Zhou X, Temam S, Oh M, et al. Global expression-based classification of lymph node metastasis and extracapsular spread of oral tongue squamous cell carcinoma. Neoplasia 2006; 8: 925-932. (Pubitemid 44706242)
6. Makizumi R, Ravikumar TS, Dong H, Yang W, Yang WL,. Bone morphogenetic protein-4 is overexpressed in colonic adenocarcinomas and promotes migration and invasion of HCT116 cells. Exp Cell Res 2007; 313: 1033-1044. (Pubitemid 46273448)
7. Yang S, Zhong C, Frenkel B, Reddi AH, Roy-Burman P,. Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Res 2005; 65: 5769-5777. (Pubitemid 40911180)
8. Langenfeld EM, Calvano SE, Abou-Nukta F, Lowry SF, Amenta P, Langenfeld J,. The mature bone morphogenetic protein-2 is aberrantly expressed in non-small cell lung carcinomas and stimulates tumor growth of A549 cells. Carcinogenesis 2003; 24: 1445-1454. (Pubitemid 37160834)
9. Willette RN, Gu JL, Lysko PG, Anderson KM, Minehart H, Yue T-L,. BMP-2 gene expression and effects on human vascular smooth muscle cells. J Vasc Res 1999; 36: 120-125. (Pubitemid 29210918)
10. Simic P, Culej JB, Orlic I, Grgurevic L, Draca N, Spaventi R, Vukicevic S,. Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption. J Biol Chem 2006; 281: 25509-25521. (Pubitemid 44401940)
11. Jin Y, Tipoe GL, Liong EC, et al. Overexpression of BMP-2/4, -5 and BMPR-1A is associated with malignancy of oral epithelium. Oral Oncol 2001; 37: 225-233. (Pubitemid 32245846)
12. Sun J, Wei L, Liu X, Li J, Li B, Wang G, Meng F,. Influences of ionic dissolution products of dicalcium silicate coating on osteoblastic proliferation, differentiation and gene expression. Acta Biomater 2009; 5: 1284-1293.
13. Hanahan D, Weinberg RA,. The hallmarks of cancer. Cell 2000; 100: 57-70. (Pubitemid 30046295)
14. Kleeff J, Maruyama H, Ishiwata T, et al. Bone morphogenetic protein 2 diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo. Gastroenterology 1999; 116: 1202-1216. (Pubitemid 29203031)
15. Asano N, Yamakazi T, Seto M, Matsumine A, Yoshikawa H, Uchida A,. The expression and prognostic significance of bone morphogenetic protein-2 in patients with malignant fibrous histiocytoma. J Bone Joint Surg [Br] 2004; 86: 607-612. (Pubitemid 38660071)
16. Parr C, Jiang WG,. Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer. Eur J Cancer 2009; 45: 1673-1683.
17. Liu K, Wang G, Ding H, Chen Y, Yu G, Wang J,. Downregulation of metastasis suppressor 1 (MTSS1) is associated with nodal metastasis and poor outcome in Chinese patients with gastric cancer. BMC Cancer 2010; 10: 428.
18. Beck BH, Welch DR,. The KISS1 metastasis suppressor: a good night kiss for disseminated cancer cells. Eur J Cancer 2010; 46: 1283-1289.
19. Zheng S, Chang Y, Hodges KB, et al. Expression of KISS1 and MMP-9 in non-small cell lung cancer and their relations to metastasis and survival. Anticancer Res 2010; 30: 713-718.
20. Nagai K, Doi R, Katagiri F, et al. Prognostic value of metastin expression in human pancreatic cancer. J Exp Clin Cancer Res 2009; 28: 9.
21. Vidal-Vanaclocha F, Alvarez A, Asumendi A, Urcelay B, Tonino P, Dinarello CA,. Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro. J Natl Cancer Inst 1996; 88: 198-205. (Pubitemid 26065832)
22. Voronov E, Shouval DS, Krelin Y, et al. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci USA 2003; 100: 2645-2650. (Pubitemid 36297552)
23. Kessenbrock K, Plaks V, Werb Z,. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 2010; 141: 52-67.
24. Martin MD, Matrisian, LM,. The other side of MMPs: protective roles in tumor progression. Cancer Metastasis Rev 2007; 26: 717-724. (Pubitemid 350115119)
25. Wen XZ, Miyake S, Akiyama Y, Yuasa Y,. BMP-2 modulates the proliferation and differentiation of normal and cancerous gastric cells. Biochem Biophys Res Commun 2004; 316: 100-106. (Pubitemid 38299134)
26. Wu JB, Fu HQ, Huang LZ, Liu AW, Zhang JX,. Effects of siRNA targeting BMP-2 on the abilities of migration and invasion of human liver cancer SMMC7721 cells and its mechanism. Cancer Gene Ther 2011; 18: 20-25.