Adsorptive modulation of inflammatory mediators dampens endothelial cell activation

Blood Purification

Volumn 32, Issue 4, 2011, Pages 286-295

  Schildberger, Anita ^a   Buchacher, Tanja ^a   Weber, Viktoria ^a   Falkenhagen, Dieter ^a  

^a DANUBE UNIVERSITY KREMS   (Austria)

Author keywords

Adsorption; Blood purification; Endothelial cell activation; Polymers; Sepsis

Indexed keywords

ALBUMIN; COPOLYMER; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; POLYSTYRENE DIVINYLBENZENE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BLOOD COMPATIBILITY; CELL ACTIVATION; CELL CULTURE; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

ADSORPTION; CELL ADHESION MOLECULES; CELL LINE; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; POLYMERS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80052084583     PISSN: 02535068     EISSN: 14219735     Source Type: Journal    
DOI: 10.1159/000330329     Document Type: Article

References (26)

1. Aird WC: Endothelium in health and disease. Pharmacol Rep 2008; 60: 139-143. (Pubitemid 351586552)
2. Hack CE, Zeerleder S: The endothelium in sepsis: source of and a target for inflammation. Crit Care Med 2001; 29:S21-S27. (Pubitemid 32681578)
3. Matsuda N, Hattori Y: Vascular biology in sepsis: pathophysiological and therapeutic significance of vascular dysfunction. J Smooth Muscle Res 2007; 43: 117-137.
4. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR: Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29: 1303-1310. (Pubitemid 32641789)
5. Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM: Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 2004; 32: 858-873. (Pubitemid 38344143)
6. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL; International Surviving Sepsis Campaign Guidelines Committee; American Association of Critical- Care Nurses; American College of Chest Physicians; American College of Emergency Physicians; Canadian Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases; European Society of Intensive Care Medicine; European Respiratory Society; International Sepsis Forum; Japanese Association for Acute Medicine; Japanese Society of Intensive Care Medicine; Society of Critical Care Medicine; Society of Hospital Medicine; Surgical Infection Society; World Federation of Societies of Intensive and Critical Care Medicine: Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008; 36: 296-327.
7. Sarangi PP, Lee HW, Kim M: Activated protein C action in inflammation. Br J Haematol 2010; 148: 817-833.
8. Marshall JC: Such stuff as dreams are made on: mediator-directed therapy in sepsis. Nat Rev Drug Discov 2003; 2: 391-405. (Pubitemid 37361709)
9. Remick DG: Cytokine therapeutics for the treatment of sepsis: why has nothing worked? Curr Pharm Des 2003; 9: 75-82. (Pubitemid 36131707)
10. Bellomo R, Honore PM, Matson J, Ronco C, Winchester J: Extracorporeal blood treatment methods in SIRS/sepsis. Int J Artif Organs 2005; 28: 450-458. (Pubitemid 40823645)
11. Falkenhagen D, Strobl W, Vogt G, Schrefl A, Linsberger I, Gerner FJ, Schoenhofen M: Fractionated plasma separation and adsorption system: a novel system for blood purification to remove albumin bound substances. Artif Organs 1999; 23: 81-86. (Pubitemid 29047501)
12. Cruz DN, Perazella MA, Bellomo R, de Cal M, Polanco N, Corradi V, Lentini P, Nalesso F, Ueno T, Ranieri VM, Ronco C: Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review. Crit Care 2007; 11:R47.
13. Ronco C, Brendolan A, Lonnemann G, Bellomo R, Piccinni P, Digito A, Dan M, Irone M, La Greca G, Inguaggiato P, Maggiore U, De Nitti C, Wratten ML, Ricci Z, Tetta C: A pilot study of coupled plasma filtration with adsorption in septic shock. Crit Care Med 2002; 30: 1250-1255. (Pubitemid 34620967)
14. Schefold JC, von Haehling S, Corsepius M, Pohle C, Kruschke P, Zuckermann H, Volk HD, Reinke P: A novel selective extracorporeal intervention in sepsis: immunoadsorption of endotoxin, interleukin 6, and complement-activating product 5a. Shock 2007; 28: 418-425. (Pubitemid 47415252)
15. Weber V, Hartmann J, Linsberger I, Falkenhagen D: Efficient adsorption of tumor necrosis factor with an in vitro set-up of the microspheres-based detoxification system. Blood Purif 2007; 25: 169-174. (Pubitemid 46447075)
16. Weber V, Linsberger I, Ettenauer M, Loth F, Hoyhtya M, Falkenhagen D: Development of specific adsorbents for human tumor necrosis factor-alpha: influence of antibody immobilization on performance and biocompatibility. Biomacromolecules 2005; 6: 1864-1870. (Pubitemid 41052178)
17. Schildberger A, Rossmanith E, Weber V, Falkenhagen D: Monitoring of endothelial cell activation in experimental sepsis with a two-step cell culture model. Innate Immun 2010; 16: 278-287.
18. Kellum JA, Song M, Venkataraman R: Hemoadsorption removes tumor necrosis factor, interleukin-6, and interleukin-10, reduces nuclear factor-kappaB DNA binding, and improves short-term survival in lethal endotoxemia. Crit Care Med 2004; 32: 801-805. (Pubitemid 38340080)
19. Tetta C, Cavaillon JM, Schulze M, Ronco C, Ghezzi PM, Camussi G, Serra AM, Curti F, Lonnemann G: Removal of cytokines and activated complement components in an experimental model of continuous plasma filtration coupled with sorbent adsorption. Nephrol Dial Transplant 1998; 13: 1458-1464. (Pubitemid 28254321)
20. Cantaluppi V, Weber V, Lauritano C, Figliolini F, Beltramo S, Biancone L, De Cal M, Cruz D, Ronco C, Segoloni GP, Tetta C, Camussi G: Protective effect of resin adsorption on septic plasma-induced tubular injury. Crit Care 2010; 14:R4.
21. Bellomo R, Tetta C, Ronco C: Coupled plasma filtration adsorption. Intensive Care Med 2003; 29: 1222-1228. (Pubitemid 37041147)
22. Formica M, Olivieri C, Livigni S, Cesano G, Vallero A, Maio M, Tetta C: Hemodynamic response to coupled plasma filtration-adsorption in human septic shock. Intensive Care Med 2003; 29: 703-708. (Pubitemid 36609560)
23. Ronco C, Brendolan A, d'Intini V, Ricci Z, Wratten ML, Bellomo R: Coupled plasma filtration adsorption: rationale, technical development and early clinical experience. Blood Purif 2003; 21: 409-416. (Pubitemid 37346716)
24. DiLeo MV, Fisher JD, Burton BM, Federspiel WJ: Selective improvement of tumor necrosis factor capture in a cytokine hemoadsorption device using immobilized anti-tumor necrosis factor. J Biomed Mater Res B Appl Biomater 2011; 96: 127-133.
25. Hamaguchi E, Takamura T, Shimizu A, Nagai Y: Tumor necrosis factor-alpha and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal-regulated kinase- and nuclear factorkappaB- dependent pathways in cultured human umbilical vein endothelial cells. J Pharmacol Exp Ther 2003; 307: 987-994. (Pubitemid 37494216)
26. Orbe J, Chorda C, Montes R, Paramo JA: Changes in the fibrinolytic components of cultured human umbilical vein endothelial cells induced by endotoxin, tumor necrosis factor-alpha and interleukin-1alpha. Haematologica 1999; 84: 306-311. (Pubitemid 29474343)