Elaboration of peptidomimetics derived from a PADAM approach: Synthesis of polyfunctionalised 2(1H)-pyrazinones via an unexpected aromatisation

Synlett

Volumn , Issue 14, 2011, Pages 2009-2012

  Basso, Andrea ^a   Banfi, Luca ^a   Guanti, Giuseppe ^a   Riva, Renata ^a   Tosatti, Paolo ^a,b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

aromatisation; heterocycles; isocyanides; Passerini multicomponent reaction; protecting groups; ring closure

Indexed keywords

3 BENZYL N BUTYL 6 METHYL 5 OXO 4,5 DIHYDROPYRAZINE 2 CARBOXAMIDE; N (TERT BUTYL) 3 ISOPROPYL 4 OXO 6,7,8,9 TETRAHYDRO 4H PYRIDO[1,2 A]PYRAZINE 1 CARBOXAMIDE; N BUTYL 3 [[2 (N BOC AMINO)PROPIONYL]AMINO] 4 PHENYL 2 OXYBUTANAMIDE; PYRAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ACIDIFICATION; AROMATIZATION; ARTICLE; BIOMIMETICS; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; COLUMN CHROMATOGRAPHY; CYCLIZATION; EPIMERIZATION; HYDROGENATION; MULTICOMPONENT REACTION; OXIDATION; PASSERINI REACTION AMINE DEPROTECTION ACYL MIGRATION; PEPTIDOMICS; STEREOCHEMISTRY; SYNTHESIS;

EID: 80052049387     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0030-1260807     Document Type: Article

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