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Volumn 412, Issue 2, 2011, Pages 385-390

ATF3 represses PDX-1 expression in pancreatic β-cells

Author keywords

Activating transcription factor 3 (ATF3); ATF CREB responsive element (ATF CRE); Hyperglycemia; Hyperlipidemia; Pancreatic and duodenal homeobox factor 1 (PDX 1); Promoter

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ACTIVATING TRANSCRIPTION FACTOR 4; GLUCOSE; PALMITIC ACID; THAPSIGARGIN; TRANSCRIPTION FACTOR PDX 1;

EID: 80052037831     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.07.108     Document Type: Article
Times cited : (16)

References (26)
  • 1
    • 0033572844 scopus 로고    scopus 로고
    • Insulin stimulates pancreatic-duodenal homoeobox factor-1 (PDX1) DNA-binding activity and insulin promoter activity in pancreatic beta cells
    • Wu H., MacFarlane W.M., Tadayyon M., Arch J.R., James R.F., Docherty K. Insulin stimulates pancreatic-duodenal homoeobox factor-1 (PDX1) DNA-binding activity and insulin promoter activity in pancreatic beta cells. Biochem. J. 1999, 15:813-818.
    • (1999) Biochem. J. , vol.15 , pp. 813-818
    • Wu, H.1    MacFarlane, W.M.2    Tadayyon, M.3    Arch, J.R.4    James, R.F.5    Docherty, K.6
  • 2
    • 0032525981 scopus 로고    scopus 로고
    • Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
    • Ahlgren U., Jonsson J., Jonsson L., Simu K., Edlund H. Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes 1998, 12:1763-1768.
    • (1998) Genes , vol.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5
  • 5
    • 3342917161 scopus 로고    scopus 로고
    • Does the aspartic acid to asparagine substitution at position 76 in the pancreas duodenum homeobox gene (PDX1) cause late-onset type 2 diabetes?
    • Elbein S.C., Karim M.A. Does the aspartic acid to asparagine substitution at position 76 in the pancreas duodenum homeobox gene (PDX1) cause late-onset type 2 diabetes?. Diabetes Care 2004, 27:1968-1973.
    • (2004) Diabetes Care , vol.27 , pp. 1968-1973
    • Elbein, S.C.1    Karim, M.A.2
  • 7
    • 33750502270 scopus 로고    scopus 로고
    • Oxidative stress and impaired insulin secretion in type 2 diabetes
    • Robertson R.P. Oxidative stress and impaired insulin secretion in type 2 diabetes. Curr. Opin. Pharmacol. 2006, 6:615-619.
    • (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 615-619
    • Robertson, R.P.1
  • 8
    • 33644865024 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation
    • Kawamori D., Kaneto H., Nakatani Y., Matsuoka T.A., Matsuhisa M., Hori M., Yamasaki Y. The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation. J. Biol. Chem. 2006, 281:1091-1098.
    • (2006) J. Biol. Chem. , vol.281 , pp. 1091-1098
    • Kawamori, D.1    Kaneto, H.2    Nakatani, Y.3    Matsuoka, T.A.4    Matsuhisa, M.5    Hori, M.6    Yamasaki, Y.7
  • 9
    • 0036895372 scopus 로고    scopus 로고
    • Regulation of pdx-1 gene expression
    • Melloul D., Marshak S., Cerasi E. Regulation of pdx-1 gene expression. Diabetes 2002, 51(Suppl 3):320-325.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 3 , pp. 320-325
    • Melloul, D.1    Marshak, S.2    Cerasi, E.3
  • 10
    • 34250303128 scopus 로고    scopus 로고
    • Regulation of pancreas duodenum homeobox-1 expression by early growth response-1
    • Eto K., Kaur V., Thomas M.K. Regulation of pancreas duodenum homeobox-1 expression by early growth response-1. J. Biol. Chem. 2007, 282:5973-5983.
    • (2007) J. Biol. Chem. , vol.282 , pp. 5973-5983
    • Eto, K.1    Kaur, V.2    Thomas, M.K.3
  • 11
    • 1542357573 scopus 로고    scopus 로고
    • Conserved transcriptional regulatory domains of the pdx-1 gene
    • Gerrish K., Jennifer C., Velkinburgh V., Stein R. Conserved transcriptional regulatory domains of the pdx-1 gene. Mol. Endocrinol. 2004, 18:533-548.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 533-548
    • Gerrish, K.1    Jennifer, C.2    Velkinburgh, V.3    Stein, R.4
  • 13
    • 0035948624 scopus 로고    scopus 로고
    • The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis
    • Hai T., Hartman M.G. The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis. Gene 2001, 273:1-11.
    • (2001) Gene , vol.273 , pp. 1-11
    • Hai, T.1    Hartman, M.G.2
  • 14
    • 0035800759 scopus 로고    scopus 로고
    • The roles of ATF3 in glucose homeostasis: a transgenic mouse model with liver dysfunction and defects in endocrine pancreas
    • Allen-Jennings A.E., Hartman M.G., Kociba G.J., Hai T. The roles of ATF3 in glucose homeostasis: a transgenic mouse model with liver dysfunction and defects in endocrine pancreas. J. Biol. Chem. 2001, 276:29507-29514.
    • (2001) J. Biol. Chem. , vol.276 , pp. 29507-29514
    • Allen-Jennings, A.E.1    Hartman, M.G.2    Kociba, G.J.3    Hai, T.4
  • 16
    • 0036230225 scopus 로고    scopus 로고
    • Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic β-cell function
    • Busch A.K., Cordery D., Denyer G.S., Biden T.J. Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic β-cell function. Diabetes 2002, 51:977-987.
    • (2002) Diabetes , vol.51 , pp. 977-987
    • Busch, A.K.1    Cordery, D.2    Denyer, G.S.3    Biden, T.J.4
  • 17
    • 40949116757 scopus 로고    scopus 로고
    • The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis
    • Li D., Yin X., Zmuda E.J., Wolford C.C., Dong X., White M.F., Hai T. The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis. Diabetes 2008, 57:635-644.
    • (2008) Diabetes , vol.57 , pp. 635-644
    • Li, D.1    Yin, X.2    Zmuda, E.J.3    Wolford, C.C.4    Dong, X.5    White, M.F.6    Hai, T.7
  • 18
    • 33745293067 scopus 로고    scopus 로고
    • NFATc4 and ATF3 negatively regulate adiponectin gene expression in 3T3-L1 adipocytes
    • Kim H.B., Kong M., Kim T.M., Suh Y.H., Kim W.H., Lim J.H., Song J.H., Jung M.H. NFATc4 and ATF3 negatively regulate adiponectin gene expression in 3T3-L1 adipocytes. Diabetes 2006, 55:1342-1352.
    • (2006) Diabetes , vol.55 , pp. 1342-1352
    • Kim, H.B.1    Kong, M.2    Kim, T.M.3    Suh, Y.H.4    Kim, W.H.5    Lim, J.H.6    Song, J.H.7    Jung, M.H.8
  • 20
    • 77951757036 scopus 로고    scopus 로고
    • AdipoR2 is transcriptionally regulated by ER stress-inducible ATF3 in HepG2 human hepatocyte cells
    • Koh I.U., Lim J.H., Joe M.K., Kim W.H., Jung M.H., Yoon J.B., Song J. AdipoR2 is transcriptionally regulated by ER stress-inducible ATF3 in HepG2 human hepatocyte cells. FEBS. J. 2010, 277:2304-2317.
    • (2010) FEBS. J. , vol.277 , pp. 2304-2317
    • Koh, I.U.1    Lim, J.H.2    Joe, M.K.3    Kim, W.H.4    Jung, M.H.5    Yoon, J.B.6    Song, J.7
  • 21
    • 33745769040 scopus 로고    scopus 로고
    • Mitochondrial dysfunction induces aberrant insulin signalling and glucose utilisation in murine C2C12 myotube cells
    • Lim J.H., Lee J.I., Suh Y.H., Kim W., Song J.H., Jung M.H. Mitochondrial dysfunction induces aberrant insulin signalling and glucose utilisation in murine C2C12 myotube cells. Diabetologia 2006, 49:1924-1936.
    • (2006) Diabetologia , vol.49 , pp. 1924-1936
    • Lim, J.H.1    Lee, J.I.2    Suh, Y.H.3    Kim, W.4    Song, J.H.5    Jung, M.H.6
  • 22
    • 33745234081 scopus 로고    scopus 로고
    • Diabetes, glucose toxicity and oxidative stress: a case of double jeopardy for the pancreatic islet beta cell
    • Robertson R.P., Harmon J.S. Diabetes, glucose toxicity and oxidative stress: a case of double jeopardy for the pancreatic islet beta cell. Free Radic. Biol. 2006, 41:177-184.
    • (2006) Free Radic. Biol. , vol.41 , pp. 177-184
    • Robertson, R.P.1    Harmon, J.S.2
  • 23
    • 78651323561 scopus 로고    scopus 로고
    • SREBP-1c, Pdx-1, and GLP-1R involved in palmitate-EPA regulated glucose-stimulated insulin secretion in INS-1 cells
    • Shao S., Liu Z., Yang Y., Zhang M., Yu X. SREBP-1c, Pdx-1, and GLP-1R involved in palmitate-EPA regulated glucose-stimulated insulin secretion in INS-1 cells. J. Cell. Biochem. 2010, 111(3):634-642.
    • (2010) J. Cell. Biochem. , vol.111 , Issue.3 , pp. 634-642
    • Shao, S.1    Liu, Z.2    Yang, Y.3    Zhang, M.4    Yu, X.5
  • 24
    • 10744227975 scopus 로고    scopus 로고
    • Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase
    • Kawamori D., Kajimoto Y., Kaneto H., Umayahara Y., Fujitani Y., Miyatsuka T., Watada H., Leibiger I.B., Yamasaki Y., Hori M. Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase. Diabetes 2003, 52:2896-2904.
    • (2003) Diabetes , vol.52 , pp. 2896-2904
    • Kawamori, D.1    Kajimoto, Y.2    Kaneto, H.3    Umayahara, Y.4    Fujitani, Y.5    Miyatsuka, T.6    Watada, H.7    Leibiger, I.B.8    Yamasaki, Y.9    Hori, M.10
  • 25
    • 25444480496 scopus 로고    scopus 로고
    • Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans
    • Hagman D.K., Hays L.B., Parazzoli S.D., Poitout V. Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans. J. Biol. Chem. 2005, 280:32413-32418.
    • (2005) J. Biol. Chem. , vol.280 , pp. 32413-32418
    • Hagman, D.K.1    Hays, L.B.2    Parazzoli, S.D.3    Poitout, V.4
  • 26
    • 79959897450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and pancreatic β-cell death
    • Fonseca S.G., Gromada J., Urano F. Endoplasmic reticulum stress and pancreatic β-cell death. Trends Endocrinol. Metab. 2011, 22:266-274.
    • (2011) Trends Endocrinol. Metab. , vol.22 , pp. 266-274
    • Fonseca, S.G.1    Gromada, J.2    Urano, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.