Induction of diabetes with signs of autoimmunity in primates by the injection of multiple-low-dose streptozotocin

Biochemical and Biophysical Research Communications

Volumn 412, Issue 2, 2011, Pages 373-378

  Wei, Lingling ^a   Lu, Yanrong ^a   He, Sirong ^a   Jin, Xi ^a   Zeng, Li ^a   Zhang, Shuang ^a   Chen, Younan ^a   Tian, Bole ^a   Mai, Gang ^a   Yang, Guang ^a   Zhang, Jie ^a   Wang, Li ^b   Li, Hongxia ^b   Markmann, James F ^c   Cheng, Jingqiu ^a   Deng, Shaoping ^c  

^a SICHUAN UNIVERSITY   (China)

^b National Chengdu Center for Safety Evaluation of Traditional Chinese Medicine   (China)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Animal model; Autoimmunity; Multiple low dose streptozotocin; Rhesus monkey; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; GLUCOSE; HEMOGLOBIN A1C; PIG INSULIN; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DIABETOGENESIS; DISEASE SEVERITY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HISTOLOGY; HYPERGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; KIDNEY; LIVER; MALE; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRIMATE; PRIORITY JOURNAL; RHESUS MONKEY; SEROLOGY; STREPTOZOCIN DIABETES; T LYMPHOCYTE;

ANIMALS; AUTOANTIBODIES; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; ISLETS OF LANGERHANS; MACACA MULATTA; MALE; STREPTOZOCIN;

ANIMALIA; MACACA MULATTA; PRIMATES;

EID: 80052037731     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.07.105     Document Type: Article

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