Proteome profiling of wild type and lumican-deficient mouse corneas

Journal of Proteomics

Volumn 74, Issue 10, 2011, Pages 1895-1905

  Shao, HanJuan ^a   Chaerkady, Raghothama ^a,b   Chen, Shoujun ^c   Pinto, Sneha M ^b,d   Sharma, Rakesh ^e   Delanghe, Bernard ^f   Birk, David E ^c   Pandey, Akhilesh ^a   Chakravarti, Shukti ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF BIOINFORMATICS   (India)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d MANIPAL UNIVERSITY   (India)

^e NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^f THERMO FISHER SCIENTIFIC   (Germany)

Author keywords

Collagen; Cornea; ITRAQ; Lumican; Mass spectrometry; Proteomics

Indexed keywords

ALCOHOL DEHYDROGENASE; COLLAGEN TYPE 1; COLLAGEN TYPE 4; COLLAGEN TYPE 7; CYTOKERATIN 14; CYTOKERATIN 8; ENTACTIN; FIBROMODULIN; KERATOCAN; LAMININ; LUMICAN; PROTEOME; SUPEROXIDE DISMUTASE;

ARTICLE; CONTROLLED STUDY; CORNEA; CORNEA EPITHELIUM; EXTRACELLULAR MATRIX; HUMAN; MASS SPECTROMETRY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; CHONDROITIN SULFATE PROTEOGLYCANS; CORNEA; EPITHELIUM, CORNEAL; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION PROFILING; KERATAN SULFATE; MICE; PROTEOME; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

MUS;

EID: 80052036854     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2011.04.032     Document Type: Article

References (48)

1. Hassell J.R., Birk D.E. The molecular basis of corneal transparency. Exp Eye Res 2010, 91:326-335.
2. Chen S., Oldberg A., Chakravarti S., Birk D.E. Fibromodulin regulates collagen fibrillogenesis during peripheral corneal development. Dev Dyn 2010, 239:844-854.
3. Chaerkady R., Pandey A. Quantitative proteomics for identification of cancer biomarkers. Proteomics Clin Appl 2007, 1:1080-1089.
4. Nichols J.J., Green-Church K.B. Mass spectrometry-based proteomic analyses in contact lens-related dry eye. Cornea 2009, 28:1109-1117.
5. Pannebaker C., Chandler H.L., Nichols J.J. Tear proteomics in keratoconus. Mol Vis 2010, 16:1949-1957.
6. Chakravarti S. Functions of lumican and fibromodulin: lessons from knockout mice. Glycoconj J 2002, 19:287-293.
7. Saika S., Shiraishi A., Liu C.Y., Funderburgh J.L., Kao C.W., Converse R.L., et al. Role of lumican in the corneal epithelium during wound healing. J Biol Chem 2000, 275:2607-2612.
8. Wu F., Chakravarti S. Differential expression of inflammatory and fibrogenic genes and their regulation by NF-{kappa}B inhibition in a mouse model of chronic colitis. J Immunol 2007, 179:6988-7000.
9. Chakravarti S., Magnuson T., Lass J.H., Jepsen K.J., LaMantia C., Carroll H. Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J Cell Biol 1998, 141:1277-1286.
10. Ezura Y., Chakravarti S., Oldberg A., Chervoneva I., Birk D.E. Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons. J Cell Biol 2000, 151:779-788.
11. Quantock A.J., Meek K.M., Chakravarti S. An X-ray diffraction investigation of corneal structure in lumican-deficient mice. Invest Ophthalmol Vis Sci 2001, 42:1750-1756.
12. Rada J.A., Cornuet P.K., Hassell J.H. Regulation of corneal collagen fibrillogenesis in vitro by corneal keratan sulfate proteoglycan (lumican) and decorin core proteins. Exp Eye Res 1993, 56:635-648.
13. Song J., Lee Y.G., Houston J., Petroll W.M., Chakravarti S., Cavanagh H.D., et al. Neonatal corneal stromal development in the normal and lumican-deficient mouse. Invest Ophthalmol Vis Sci 2003, 44:548-557.
14. Beecher N., Chakravarti S., Joyce S., Meek K.M., Quantock A.J. Neonatal development of the corneal stroma in wild-type and lumican-null mice. Invest Ophthalmol Vis Sci 2006, 47:146-150.
15. Chakravarti S., Petroll W.M., Hassell J.R., Jester J.V., Lass J.H., Paul J., et al. Corneal opacity in lumican-null mice: defects in collagen fibril structure and packing in the posterior stroma. Invest Ophthalmol Vis Sci 2000, 41:3365-3373.
16. Vij N., Roberts L., Joyce S., Chakravarti S. Lumican suppresses cell proliferation and aids Fas-Fas ligand mediated apoptosis: implications in the cornea. Exp Eye Res 2004, 78:957-971.
17. Vij N., Roberts L., Joyce S., Chakravarti S. Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling. Invest Ophthalmol Vis Sci 2005, 46:88-95.
18. Danielson K.G., Baribault H., Holmes D.F., Graham H., Kadler K.E., Iozzo R.V. Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J Cell Biol 1997, 136:729-743.
19. Zhang G., Chen S., Goldoni S., Calder B.W., Simpson H.C., Owens R.T., et al. Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan. J Biol Chem 2009, 284:8888-8897.
20. Chakravarti S., Paul J., Roberts L., Chervoneva I., Oldberg A., Birk D.E. Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice. Invest Ophthalmol Vis Sci 2003, 44:2422-2432.
21. Meek K.M., Quantock A.J., Boote C., Liu C.Y., Kao W.W. An X-ray scattering investigation of corneal structure in keratocan-deficient mice. Matrix Biol 2003, 22:467-475.
22. Wu F., Lee S., Schumacher M., Jun A., Chakravarti S. Differential gene expression patterns of the developing and adult mouse cornea compared to the lens and tendon. Exp Eye Res 2008, 87:214-225.
23. Norman B., Davis J., Piatigorsky J. Postnatal gene expression in the normal mouse cornea by SAGE. Invest Ophthalmol Vis Sci 2004, 45:429-440.
24. Noonan D., Hassell J. Perlecan, the large low-density proteoglycan of basement membranes: Structure and variant forms. Kidney Int 1993, 43:53-60.
25. Chakravarti S., Tam M., Chung A. The basement membrane glycoprotein entactin promotes cell attachment and binds calcium ions. J Biol Chem 1990, 265:10597-10603.
26. Ekblom M., Falk M., Salmivirta K., Durbeej M., Ekblom P. Laminin isoforms and epithelial development. Ann N Y Acad Sci 1998, 23(857):194-211.
27. Knight D.P. Unconventional collagens. J Cell Sci 2000, 113(Pt 23):4141-4142.
28. Govindarajan B., Gipson I.K. Membrane-tethered mucins have multiple functions on the ocular surface. Exp Eye Res 2010, 90:655-663.
29. S. Merjava, K. Brejchova, A. Vernon, J.T. Daniels, K. Jirsova. Cytokeratin 8 is expressed in human corneoconjunctival epithelium, particularly in limbal epithelial cells. Invest Ophthalmol Vis Sci.52:787-94.
30. Carlson E.C., Liu C.Y., Chikama T., Hayashi Y., Kao C.W., Birk D.E., et al. Keratocan, a cornea-specific keratan sulfate proteoglycan, is regulated by lumican. J Biol Chem 2005, 280:25541-25547.
31. Jepsen K.J., Wu F., Peragallo J.H., Paul J., Roberts L., Ezura Y., et al. A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice. J Biol Chem 2002, 277:35532-35540.
32. Munier F., Korvatska E., Djemai A., Paslier D.L., Zografos L., Pescia G., et al. Kerato-epithelin mutations in four 5q31-linked corneal dystrophies. Nat Genet 1997, 15:247-251.
33. Jester J.V. Corneal crystallins and the development of cellular transparency. Semin Cell Dev Biol 2008, 19:82-93.
34. Lassen N., Black W.J., Estey T., Vasiliou V. The role of corneal crystallins in the cellular defense mechanisms against oxidative stress. Semin Cell Dev Biol 2008, 19:100-112.
35. Piatigorsky J. Enigma of the abundant water-soluble cytoplasmic proteins of the cornea: the "refracton" hypothesis. Cornea 2001, 20:853-858.
36. Nezzar H., Chiambaretta F., Marceau G., Blanchon L., Faye B., Dechelotte P., et al. Molecular and metabolic retinoid pathways in the human ocular surface. Mol Vis 2007, 13:1641-1650.
37. Ubels J.L., Iorfino A., O'Brien W.J. Retinoic acid decreases the number of EGF receptors in corneal epithelium and Chang conjunctival cells. Exp Eye Res 1991, 52:763-765.
38. Zhang J.C., Claffey K., Sakthivel R., Darzynkiewicz Z., Shaw D.E., Leal J., et al. Two-chain high molecular weight kininogen induces endothelial cell apoptosis and inhibits angiogenesis: partial activity within domain 5. FASEB J 2000, 14:2589-2600.
39. Shirai R., Hirano F., Ohkura N., Ikeda K., Inoue S. Up-regulation of the expression of leucine-rich alpha(2)-glycoprotein in hepatocytes by the mediators of acute-phase response. Biochem Biophys Res Commun 2009, 382:776-779.
40. Linton J.M., Martin G.R., Reichardt L.F. The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression. Development 2007, 134:2501-2509.
41. Qi H., Shine H.D., Li D.Q., de Paiva C.S., Farley W.J., Jones D.B., et al. Glial cell-derived neurotrophic factor gene delivery enhances survival of human corneal epithelium in culture and the overexpression of GDNF in bioengineered constructs. Exp Eye Res 2008, 87:580-586.
42. You L., Ebner S., Kruse F.E. Glial cell-derived neurotrophic factor (GDNF)-induced migration and signal transduction in corneal epithelial cells. Invest Ophthalmol Vis Sci 2001, 42:2496-2504.
43. Kenney M.C., Brown D.J. The cascade hypothesis of keratoconus. Cont Lens Anterior Eye 2003, 26:139-146.
44. Mootha V.V., Kanoff J.M., Shankardas J., Dimitrijevich S. Marked reduction of alcohol dehydrogenase in keratoconus corneal fibroblasts. Mol Vis 2009, 15:706-712.
45. Cheng E.L., Maruyama I., SundarRaj N., Sugar J., Feder R.S., Yue B.Y. Expression of type XII collagen and hemidesmosome-associated proteins in keratoconus corneas. Curr Eye Res 2001, 22:333-340.
46. Lin H.J., Wan L., Tsai Y., Chen W.C., Tsai S.W., Tsai F.J. The association between lumican gene polymorphisms and high myopia. Eye (Lond) 2010, 24:1093-1101.
47. Metlapally R., Ki C.S., Li Y.J., Tran-Viet K.N., Abbott D., Malecaze F., et al. Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort. Invest Ophthalmol Vis Sci 2010, 51:4476-4479.
48. Chakravarti S., Paul J., Roberts L., Chervoneva I., Oldberg A., Birk D.E. Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice. Invest Ophthalmol Vis Sci 2003, 44:2422-2432.