Efficacy of the motile sperm organelle morphology examination (MSOME) in predicting pregnancy after intrauterine insemination

Reproductive Biology and Endocrinology

Volumn 9, Issue , 2011, Pages

  Akl, Livia D ^a   Oliveira, Joao Batista A ^a,b,c   Petersen, Claudia G ^a,b,c   Mauri, Ana L ^b,c   Silva, Liliane F I ^a,b,c   Massaro, Fabiana C ^b,c   Baruffi, Ricardo L R ^b,c   Cavagna, Mario ^b,c   Franco Jr, Jose G ^a,b,c  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b Center for Human Reproduction Prof Franco Junior   (Brazil)

^c Paulista Center for Diagnosis Research and Training   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT CHORIONIC GONADOTROPIN; RECOMBINANT FOLLITROPIN;

ADULT; ARTICLE; CELL ORGANELLE; CELL STRUCTURE; FEMALE; HUMAN; HUMAN CELL; INTRAUTERINE INSEMINATION; MALE; PREDICTIVE VALUE; PREGNANCY; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SPERMATOZOON MOTILITY; TRANSVAGINAL ECHOGRAPHY; ARTIFICIAL INSEMINATION; CYTOLOGY; MALE INFERTILITY; METHODOLOGY; PREGNANCY RATE; SEMEN ANALYSIS; SPERMATOZOON;

ADULT; FEMALE; HUMANS; INFERTILITY, MALE; INSEMINATION; INSEMINATION, ARTIFICIAL, HOMOLOGOUS; MALE; PREGNANCY; PREGNANCY RATE; SEMEN ANALYSIS; SENSITIVITY AND SPECIFICITY; SPERM MOTILITY; SPERMATOZOA;

EID: 80052035222     PISSN: None     EISSN: 14777827     Source Type: Journal    
DOI: 10.1186/1477-7827-9-120     Document Type: Article

References (65)

1. Group TECW Intrauterine insemination. Hum Reprod Update 2009, 15:265-277. Group TECW.
2. Marchetti C, Dewailly D. Intrauterine insemination: indications and methods. Rev Prat 2006, 56:500-506.
3. Bensdorp AJ, Cohlen BJ, Heineman MJ, Vandekerckhove P. Intra-uterine insemination for male subfertility. Cochrane Database Syst Rev 2007, CD000360.
4. Baccetti B. Microscopical advances in assisted reproduction. J Submicrosc Cytol Pathol 2004, 36:333-339.
5. Gianaroli L, Magli MC, Ferraretti AP, Crippa A, Lappi M, Capitani S, Baccetti B. Birefringence characteristics in sperm heads allow for the selection of reacted spermatozoa for intracytoplasmic sperm injection. Fertil Steril 2010, 93:807-813. 10.1016/j.fertnstert.2008.10.024, 19064263.
6. Petersen CG, Vagnini LD, Mauri AL, Massaro FC, Cavagna M, Baruffi RL, Oliveira JB, Franco JG. Relationship between DNA damage and sperm head birefringence. Reprod Biomed Online 2011, 22:583-589. 10.1016/j.rbmo.2011.03.017, 21507722.
7. Razavi SH, Nasr-Esfahani MH, Deemeh MR, Shayesteh M, Tavalaee M. Evaluation of zeta and HA-binding methods for selection of spermatozoa with normal morphology, protamine content and DNA integrity. Andrologia 2010, 42:13-19. 10.1111/j.1439-0272.2009.00948.x, 20078511.
8. Prinosilova P, Kruger T, Sati L, Ozkavukcu S, Vigue L, Kovanci E, Huszar G. Selectivity of hyaluronic acid binding for spermatozoa with normal Tygerberg strict morphology. Reprod Biomed Online 2009, 18:177-183. 10.1016/S1472-6483(10)60253-2, 19192336.
9. Petersen CG, Massaro FC, Mauri AL, Oliveira JB, Baruffi RL, Franco JG. Efficacy of hyaluronic acid binding assay in selecting motile spermatozoa with normal morphology at high magnification. Reprod Biol Endocrinol 2010, 8:149. 10.1186/1477-7827-8-149, 3016298, 21129168.
10. Ombelet W, Bosmans E, Janssen M, Cox A, Vlasselaer J, Gyselaers W, Vandeput H, Gielen J, Pollet H, Maes M, et al. Semen parameters in a fertile versus subfertile population: a need for change in the interpretation of semen testing. Hum Reprod 1997, 12:987-993. 10.1093/humrep/12.5.987, 9194652.
11. Menkveld R, Wong WY, Lombard CJ, Wetzels AM, Thomas CM, Merkus HM, Steegers-Theunissen RP. Semen parameters, including WHO and strict criteria morphology, in a fertile and subfertile population: an effort towards standardization of in-vivo thresholds. Hum Reprod 2001, 16:1165-1171. 10.1093/humrep/16.6.1165, 11387287.
12. Coetzee K, Kruge TF, Lombard CJ. Predictive value of normal sperm morphology: a structured literature review. Hum Reprod Update 1998, 4:73-82. 10.1093/humupd/4.1.73, 9622414.
13. Gunalp S, Onculoglu C, Gurgan T, Kruger TF, Lombard CJ. A study of semen parameters with emphasis on sperm morphology in a fertile population: an attempt to develop clinical thresholds. Hum Reprod 2001, 16:110-114. 10.1093/humrep/16.1.110, 11139547.
14. Kruger T, Van der Merwe F, Van Waart J. The Tygerberg strict criteria: what are the clinical thresholds for in vitro fertilization, intrauterine insemination, and in vivo fertilization?. Atlas of Human Sperm Morphology Evaluation 2004, 13-18. London: Taylor and Francis, Kruger T, Franken D.
15. van der Merwe FH, Kruger TF, Oehninger SC, Lombard CJ. The use of semen parameters to identify the subfertile male in the general population. Gynecol Obstet Invest 2005, 59:86-91. 10.1159/000082368, 15572878.
16. Tasdemir I, Tasdemir M, Tavukcuoglu S, Kahraman S, Biberoglu K. Effect of abnormal sperm head morphology on the outcome of intracytoplasmic sperm injection in humans. Hum Reprod 1997, 12:1214-1217. 10.1093/humrep/12.6.1214, 9222003.
17. De Vos A, Van De Velde H, Joris H, Verheyen G, Devroey P, Van Steirteghem A. Influence of individual sperm morphology on fertilization, embryo morphology, and pregnancy outcome of intracytoplasmic sperm injection. Fertil Steril 2003, 79:42-48. 10.1016/S0015-0282(02)04571-5, 12524062.
18. Baccetti B, Capitani S, Collodel G, Estenoz M, Gambera L, Piomboni P. Infertile spermatozoa in a human carrier of robertsonian translocation 14;22. Fertil Steril 2002, 78:1127-1130. 10.1016/S0015-0282(02)03379-4, 12414006.
19. Chemes EH, Rawe YV. Sperm pathology: a step beyond descriptive morphology. Origin, characterization and fertility potential of abnormal sperm phenotypes in infertile men. Hum Reprod Update 2003, 9:405-428. 10.1093/humupd/dmg034, 14640375.
20. Palermo GD, Neri QV, Takeuchi T, Rosenwaks Z. ICSI: where we have been and where we are going. Semin Reprod Med 2009, 27:191-201. 10.1055/s-0029-1202309, 19247922.
21. Berkovitz A, Eltes F, Soffer Y, Zabludovsky N, Beyth Y, Farhi J, Levran D, Bartoov B. ART success and in vivo sperm cell selection depend on the ultramorphological status of spermatozoa. Andrologia 1999, 31:1-8.
22. Bartoov B, Berkovitz A, Eltes F. Selection of spermatozoa with normal nuclei to improve the pregnancy rate with intracytoplasmic sperm injection. N Engl J Med 2001, 345:1067-1068. 10.1056/NEJM200110043451416, 11586970.
23. Bartoov B, Berkovitz A, Eltes F, Kogosowski A, Menezo Y, Barak Y. Real-time fine morphology of motile human sperm cells is associated with IVF-ICSI outcome. J Androl 2002, 23:1-8.
24. Bartoov B, Berkovitz A, Eltes F, Kogosovsky A, Yagoda A, Lederman H, Artzi S, Gross M, Barak Y. Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection. Fertil Steril 2003, 80:1413-1419. 10.1016/j.fertnstert.2003.05.016, 14667877.
25. Antinori M, Licata E, Dani G, Cerusico F, Versaci C, d'Angelo D, Antinori S. Intracytoplasmic morphologically selected sperm injection: a prospective randomized trial. Reprod Biomed Online 2008, 16:835-841. 10.1016/S1472-6483(10)60150-2, 18549694.
26. Nadalini M, Tarozzi N, Distratis V, Scaravelli G, Borini A. Impact of intracytoplasmic morphologically selected sperm injection on assisted reproduction outcome: a review. Reprod Biomed Online 2009, 19(Suppl 3):45-55.
27. Oliveira JB, Massaro FC, Mauri AL, Petersen CG, Nicoletti AP, Baruffi RL, Franco JG. Motile sperm organelle morphology examination is stricter than Tygerberg criteria. Reprod Biomed Online 2009, 18:320-326. 10.1016/S1472-6483(10)60088-0, 19298729.
28. Oliveira JB, Massaro FC, Baruffi RL, Mauri AL, Petersen CG, Silva LF, Vagnini LD, Franco JG. Correlation between semen analysis by motile sperm organelle morphology examination and sperm DNA damage. Fertil Steril 2010, 94:1937-1940. 10.1016/j.fertnstert.2010.01.042, 20189558.
29. World Health Organization WHO laboratory manual for the examination and processing of human semen 2010, Geneva: World Health Organization, 5, World Health Organization.
30. Vagnini L, Baruffi RL, Mauri AL, Petersen CG, Massaro FC, Pontes A, Oliveira JB, Franco JG. The effects of male age on sperm DNA damage in an infertile population. Reproductive biomedicine online 2007, 15:514-519. 10.1016/S1472-6483(10)60382-3, 18028741.
31. Franco JG, Baruffi RL, Mauri AL, Petersen CG, Oliveira JB, Vagnini L. Significance of large nuclear vacuoles in human spermatozoa: implications for ICSI. Reprod Biomed Online 2008, 17:42-45. 10.1016/S1472-6483(10)60291-X, 18616888.
32. Berkovitz A, Eltes F, Yaari S, Katz N, Barr I, Fishman A, Bartoov B. The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm. Hum Reprod 2005, 20:185-190.
33. ASTM Standard E1951-02 Physical and Mechanical Testing Standards West Conshohocken, PA. ASTM., http://www.astm.org
34. Press WH. Numerical recipes in FORTRAN: the art of scientific computing 1992, Cambridge England; New York, NY, USA: Cambridge University Press, 2.
35. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982, 143:29-36.
36. DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1988, 44:837-845. 10.2307/2531595, 3203132.
37. Merviel P, Heraud MH, Grenier N, Lourdel E, Sanguinet P, Copin H. Predictive factors for pregnancy after intrauterine insemination (IUI): an analysis of 1038 cycles and a review of the literature. Fertil Steril 2010, 93:79-88. 10.1016/j.fertnstert.2008.09.058, 18996517.
38. Badawy A, Elnashar A, Eltotongy M. Effect of sperm morphology and number on success of intrauterine insemination. Fertil Steril 2009, 91:777-781. 10.1016/j.fertnstert.2007.12.010, 18304534.
39. Dorjpurev U, Kuwahara A, Yano Y, Taniguchi T, Yamamoto Y, Suto A, Tanaka Y, Matsuzaki T, Yasui T, Irahara M. Effect of semen characteristics on pregnancy rate following intrauterine insemination. J Med Invest 2011, 58:127-133. 10.2152/jmi.58.127, 21372497.
40. Kamath MS, Bhave P, Aleyamma T, Nair R, Chandy A, Mangalaraj AM, Muthukumar K, George K. Predictive factors for pregnancy after intrauterine insemination: A prospective study of factors affecting outcome. J Hum Reprod Sci 2010, 3:129-134. 10.4103/0974-1208.74154, 3017328, 21234173.
41. Wainer R, Albert M, Dorion A, Bailly M, Bergere M, Lombroso R, Gombault M, Selva J. Influence of the number of motile spermatozoa inseminated and of their morphology on the success of intrauterine insemination. Hum Reprod 2004, 19:2060-2065. 10.1093/humrep/deh390, 15243004.
42. Matorras R, Osuna C, Exposito A, Crisol L, Pijoan JI. Recombinant FSH versus highly purified FSH in intrauterine insemination: systematic review and metaanalysis. Fertil Steril 2011, 95:1937-1942. e1933, 10.1016/j.fertnstert.2011.02.030, 21429486.
43. Allegra A, Marino A, Coffaro F, Scaglione P, Sammartano F, Rizza G, Volpes A. GnRH antagonist-induced inhibition of the premature LH surge increases pregnancy rates in IUI-stimulated cycles. A prospective randomized trial. Hum Reprod 2007, 22:101-108.
44. Cantineau AE, Cohlen BJ, Klip H, Heineman MJ. The addition of GnRH antagonists in intrauterine insemination cycles with mild ovarian hyperstimulation does not increase live birth rates--a randomized, double-blinded, placebo-controlled trial. Hum Reprod 2011, 26:1104-1111. 10.1093/humrep/der033, 21339196.
45. Lazaros L, Kaponis A, Vartholomatos G, Hatzi E, Botsari S, Plachouras N, Makrydimas G, Zikopoulos K, Sofikitis N, Georgiou I. Using semen flow cytometry to evaluate association of ploidy status and chromatin condensation of spermatozoa with conventional semen parameters: clinical application in intrauterine insemination. Fertil Steril 2011, 95:110-115. 10.1016/j.fertnstert.2010.05.012, 20667800.
46. van der Poel N, Farquhar C, Abou-Setta AM, Benschop L, Heineman MJ. Soft versus firm catheters for intrauterine insemination. Cochrane Database Syst Rev 2010, CD006225.
47. Burr RW, Siegberg R, Flaherty SP, Wang XJ, Matthews CD. The influence of sperm morphology and the number of motile sperm inseminated on the outcome of intrauterine insemination combined with mild ovarian stimulation. Fertil Steril 1996, 65:127-132.
48. Belaisch-Allart J, Mayenga JM, Plachot M. [Intra-uterine insemination]. Contracept Fertil Sex 1999, 27:614-619.
49. Guerif F. [Which assisted reproduction technique as a function of sperm morphology?]. Gynecol Obstet Fertil 2010, 38:508-510. 10.1016/j.gyobfe.2010.07.002, 20692863.
50. Karabinus DS, Gelety TJ. The impact of sperm morphology evaluated by strict criteria on intrauterine insemination success. Fertil Steril 1997, 67:536-541. 10.1016/S0015-0282(97)80082-9, 9091343.
51. Cooper TG, Noonan E, von Eckardstein S, Auger J, Baker HW, Behre HM, Haugen TB, Kruger T, Wang C, Mbizvo MT, Vogelsong KM. World Health Organization reference values for human semen characteristics. Hum Reprod Update 2010, 16:231-245. 10.1093/humupd/dmp048, 19934213.
52. Oliveira JB, Petersen CG, Massaro FC, Baruffi RL, Mauri AL, Silva LF, Ricci J, Franco JG. Motile sperm organelle morphology examination (MSOME): intervariation study of normal sperm and sperm with large nuclear vacuoles. Reprod Biol Endocrinol 2010, 8:56. 10.1186/1477-7827-8-56, 2889997, 20529256.
53. Bartoov B, Fisher J, Eltes F, Langzam J, Lunenfeld B. A comparative morphological analysis of abnormal human spermatozoa. Advances in Diagnosis and Treatment of Infertility 1981, 355-373. Amsterdam: Elsevier/North Holland, Insler V, Bettendorf G.
54. Berkovitz A, Eltes F, Ellenbogen A, Peer S, Feldberg D, Bartoov B. Does the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome?. Hum Reprod 2006, 21:1787-1790. 10.1093/humrep/del049, 16497697.
55. Franco JG, Mauri AL, Petersen CG, Massaro FC, Silva LF, Felipe V, Cavagna M, Pontes A, Baruffi RL, Oliveira JB, Vagnini LD. Large nuclear vacuoles are indicative of abnormal chromatin packaging in human spermatozoa. Int J Andro 2011,
56. Garolla A, Fortini D, Menegazzo M, De Toni L, Nicoletti V, Moretti A, Selice R, Engl B, Foresta C. High-power microscopy for selecting spermatozoa for ICSI by physiological status. Reprod Biomed Online 2008, 17:610-616. 10.1016/S1472-6483(10)60307-0, 18983744.
57. Toshimori K, Ito C. Human sperm ultrastructures and fertility. J Mamm Ova Res 2008, 25:232-239.
58. Gopalkrishnan K, Padwal V, Meherji PK, Gokral JS, Shah R, Juneja HS. Poor quality of sperm as it affects repeated early pregnancy loss. Arch Androl 2000, 45:111-117. 10.1080/014850100418800, 11028929.
59. Kacem O, Sifer C, Barraud-Lange V, Ducot B, De Ziegler D, Poirot C, Wolf J. Sperm nuclear vacuoles, as assessed by motile sperm organellar morphological examination, are mostly of acrosomal origin. Reprod Biomed Online 2010, 20:132-137. 10.1016/j.rbmo.2009.10.014, 20158998.
60. Junca A, Cohen-Bacrie P, Hazout A. Improvement of fertilization and pregnancy rate after intracytoplasmic fine morphologically selected sperm injection. Fertil Steril 2004, 82:S173.
61. Hazout A, Dumont-Hassan M, Junca AM, Cohen Bacrie P, Tesarik J. High-magnification ICSI overcomes paternal effect resistant to conventional ICSI. Reprod Biomed Online 2006, 12:19-25. 10.1016/S1472-6483(10)60975-3, 16454928.
62. Vanderzwalmen P, Hiemer A, Rubner P, Bach M, Neyer A, Stecher A, Uher P, Zintz M, Lejeune B, Vanderzwalmen S, et al. Blastocyst development after sperm selection at high magnification is associated with size and number of nuclear vacuoles. Reprod Biomed Online 2008, 17:617-627. 10.1016/S1472-6483(10)60308-2, 18983745.
63. Tasaka A, Doshida M, Sato Y, Kyoya T, Nakajo Y, Kyono K. Outcome of IMSI (intracytoplasmic morphologically selected sperm injection) in patients with repeated ICSI failures. Fertil Steril 2009, 92:S76.
64. Bar-Chama N, Schiff J, Luna M, Dann AB, Copperman JB. The level of sperm vacuoles in the fresh post-processed sperm sample significantly affects IVF cycle outcomes. Fertil Steril 2007, 88:S18.
65. Franken DR, Kruger TF. The what is a normal spermatozoon?. Atlas of Human Sperm Morphology Evaluation 2004, 49-74. London: Taylor and Francis, Kruger TF, Franken DR.