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Volumn 90, Issue 3, 2011, Pages 455-460

In vitro testing for hypersensitivity-mediated adverse drug reactions: Challenges and future directions

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ALLOPURINOL; ANTICONVULSIVE AGENT; AZATHIOPRINE; BETA LACTAM ANTIBIOTIC; CYTOKINE; DAPSONE; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; IODINATED CONTRAST MEDIUM; MINOCYCLINE; NEVIRAPINE; NONSTEROID ANTIINFLAMMATORY AGENT; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULFONAMIDE; TERBINAFINE; TUMOR NECROSIS FACTOR ALPHA;

EID: 80052024836     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2011.155     Document Type: Article
Times cited : (16)

References (40)
  • 1
    • 84861305959 scopus 로고    scopus 로고
    • Adverse drug reactions in hospital in-patients: A prospective analysis of 3695 patient-episodes
    • Davies, E.C., Green, C.F., Taylor, S., Williamson, P.R., Mottram, D.R. & Pirmohamed, M. Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes. PLoS ONE 4, e4439 (2009).
    • (2009) PLoS ONE , vol.4
    • Davies, E.C.1    Green, C.F.2    Taylor, S.3    Williamson, P.R.4    Mottram, D.R.5    Pirmohamed, M.6
  • 3
    • 0001774061 scopus 로고
    • Mechanisms of adverse drug reactions
    • (ed. Davies, D.) Oxford University Press, Oxford, UK
    • Rawlins, M., Thompson, J. Mechanisms of adverse drug reactions. In: Textbook of Adverse Drug Reactions. (ed. Davies, D.) 18-45 (Oxford University Press, Oxford, UK, 1991).
    • (1991) Textbook of Adverse Drug Reactions , pp. 18-45
    • Rawlins, M.1    Thompson, J.2
  • 4
    • 84874613829 scopus 로고    scopus 로고
    • Drug hypersensitivity reactions: Classification and relationship to T-cell activation
    • (ed. Pichler, W.) Karger, Basel, Switzerland
    • P ichler, W. Drug hypersensitivity reactions: Classification and relationship to T-cell activation. In: Drug Hypersensitivity. (ed. Pichler, W.) 168-189 (Karger, Basel, Switzerland, 2007).
    • (2007) Drug Hypersensitivity , pp. 168-189
    • Pichler, W.1
  • 5
    • 0001082980 scopus 로고
    • Classification of allergic reactions responsible for clinical hypersensitivity and disease
    • (eds. Gell, P., Coombs, R. & Lachmann, P.) Blackwell, London
    • Coombs, R. & Gell, P. Classification of allergic reactions responsible for clinical hypersensitivity and disease. In: Clinical Aspects of Immunology. (eds. Gell, P., Coombs, R. & Lachmann, P.) 761-781 (Blackwell, London, 1975).
    • (1975) Clinical Aspects of Immunology , pp. 761-781
    • Coombs, R.1    Gell, P.2
  • 6
    • 0003190104 scopus 로고
    • Studies on the mechanism of the formation of the penicillin antigen. III. The N-(D-alpha-benzylpenicilloyl) group as an antigenic determinant responsible for hypersensitivity to penicillin G
    • Levine, B.B. & Ovary, Z. Studies on the mechanism of the formation of the penicillin antigen. III. The N-(D-alpha-benzylpenicilloyl) group as an antigenic determinant responsible for hypersensitivity to penicillin G. J. Exp. Med. 114, 875-904 (1961).
    • (1961) J. Exp. Med. , vol.114 , pp. 875-904
    • Levine, B.B.1    Ovary, Z.2
  • 7
    • 79953811482 scopus 로고    scopus 로고
    • The in vitro platelet toxicity assay (iPTA): A novel approach for assessment of drug hypersensitivity syndrome
    • Elzagallaai, A.A., Rieder, M.J. & Koren, G. The in vitro platelet toxicity assay (iPTA): a novel approach for assessment of drug hypersensitivity syndrome. J. Clin. Pharmacol. 51, 428-435 (2011).
    • (2011) J. Clin. Pharmacol. , vol.51 , pp. 428-435
    • Elzagallaai, A.A.1    Rieder, M.J.2    Koren, G.3
  • 8
    • 65949091607 scopus 로고    scopus 로고
    • Patch testing for the diagnosis of anticonvulsant hypersensitivity syndrome: A systematic review
    • Elzagallaai, A.A., Knowles, S.R., Rieder, M.J., Bend, J.R., Shear, N.H. & Koren, G. Patch testing for the diagnosis of anticonvulsant hypersensitivity syndrome: a systematic review. Drug Saf. 32, 391-408 (2009).
    • (2009) Drug Saf. , vol.32 , pp. 391-408
    • Elzagallaai, A.A.1    Knowles, S.R.2    Rieder, M.J.3    Bend, J.R.4    Shear, N.H.5    Koren, G.6
  • 9
    • 79959905166 scopus 로고    scopus 로고
    • Severe bullous hypersensitivity reactions after exposure to carbamazepine in a Han-Chinese child with a positive HLA-B*1502 and negative in vitro toxicity assays: Evidence for different pathophysiological mechanisms
    • Elzagallaai, A.A., Garcia-Bournissen, F., Finkelstein, Y., Bend, J.R., Rieder, M.J. & Koren, G. Severe bullous hypersensitivity reactions after exposure to carbamazepine in a Han-Chinese child with a positive HLA-B*1502 and negative in vitro toxicity assays: evidence for different pathophysiological mechanisms. J. Popul. Ther. Clin. Pharmacol. 18, e1-e9 (2011).
    • (2011) J. Popul. Ther. Clin. Pharmacol. , vol.18
    • Elzagallaai, A.A.1    Garcia-Bournissen, F.2    Finkelstein, Y.3    Bend, J.R.4    Rieder, M.J.5    Koren, G.6
  • 10
    • 33745894681 scopus 로고    scopus 로고
    • Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: Does a DRESS syndrome really exist?
    • Network of the French Pharmacovigilance Centers
    • P eyriie, H. et al.; Network of the French Pharmacovigilance Centers. Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist? Br. J. Dermatol. 155, 422-428 (2006).
    • (2006) Br. J. Dermatol. , vol.155 , pp. 422-428
    • Peyriie, H.1
  • 15
    • 13244294124 scopus 로고    scopus 로고
    • A new combined test with flowcytometric basophil activation and determination of sulfidoleukotrienes is useful for in vitro diagnosis of hypersensitivity to aspirin and other nonsteroidal anti-inflammatory drugs
    • DOI 10.1159/000082586
    • S anz, M.L., Gamboa, P. & de Weck, A.L. A new combined test with flowcytometric basophil activation and determination of sulfidoleukotrienes is useful for in vitro diagnosis of hypersensitivity to aspirin and other nonsteroidal anti-inflammatory drugs. Int. Arch. Allergy Immunol. 136, 58-72 (2005). (Pubitemid 40187031)
    • (2005) International Archives of Allergy and Immunology , vol.136 , Issue.1 , pp. 58-72
    • Sanz, M.L.1    Gamboa, P.2    De Weck, A.L.3
  • 16
    • 70350212578 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug hypersensitivity syndrome A multicenter study. I. Clinical findings and in vitro diagnosis
    • De Weck, A.L. et al. Nonsteroidal anti-inflammatory drug hypersensitivity syndrome. A multicenter study. I. Clinical findings and in vitro diagnosis. J. Investig. Allergol. Clin. Immunol. 19, 355-369 (2009).
    • (2009) J. Investig. Allergol. Clin. Immunol. , vol.19 , pp. 355-369
    • De Weck, A.L.1
  • 17
    • 77953657779 scopus 로고    scopus 로고
    • In vitro diagnosis of immediate allergic reactions to drugs: An update
    • Immunology Committee of the Spanish Society of Allergology and Clinical Immunology of the SEAIC
    • Mayorga, C. et al.; Immunology Committee of the Spanish Society of Allergology and Clinical Immunology of the SEAIC. In vitro diagnosis of immediate allergic reactions to drugs: an update. J. Investig. Allergol. Clin. Immunol. 20, 103-109 (2010).
    • (2010) J. Investig. Allergol. Clin. Immunol. , vol.20 , pp. 103-109
    • Mayorga, C.1
  • 18
    • 0029200041 scopus 로고
    • Lymphocyte transformation test in the diagnosis of immediate type hypersensitivity reactions to penicillins
    • Bircher, A.J. Lymphocyte transformation test in the diagnosis of immediate type hypersensitivity reactions to penicillins. Curr. Probl. Dermatol. 22, 31-37 (1995).
    • (1995) Curr. Probl. Dermatol. , vol.22 , pp. 31-37
    • Bircher, A.J.1
  • 20
    • 0034605712 scopus 로고    scopus 로고
    • Idiosyncratic drug reactions: The reactive metabolite syndromes
    • Knowles, S.R., Uetrecht, J. & Shear, N.H. Idiosyncratic drug reactions: the reactive metabolite syndromes. Lancet 356, 1587-1591 (2000).
    • (2000) Lancet , vol.356 , pp. 1587-1591
    • Knowles, S.R.1    Uetrecht, J.2    Shear, N.H.3
  • 22
    • 33847081148 scopus 로고    scopus 로고
    • Idiosyncratic drug reactions: Current understanding
    • Uetrecht, J. Idiosyncratic drug reactions: current understanding. Annu. Rev. Pharmacol. Toxicol. 47, 513-539 (2007).
    • (2007) Annu. Rev. Pharmacol. Toxicol. , vol.47 , pp. 513-539
    • Uetrecht, J.1
  • 24
    • 0021952693 scopus 로고
    • 3H]benzo(a)pyrene-treated rabbits
    • Horton, J.K., Rosenior, J.C., Bend, J.R. & Anderson, M.W. Quantitation of benzo(a)pyrene metabolite: DNA adducts in selected hepatic and pulmonary cell types isolated from [3H]benzo(a)pyrene-treated rabbits. Cancer Res. 45, 3477-3481 (1985). (Pubitemid 15226410)
    • (1985) Cancer Research , vol.45 , Issue.8 , pp. 3477-3481
    • Horton, J.K.1    Rosenior, J.C.2    Bend, J.R.3    Anderson, M.W.4
  • 26
    • 0019416541 scopus 로고
    • Predisposition to phenytoin hepatotoxicity assessed in vitro
    • S pielberg, S.P., Gordon, G.B., Blake, D.A., Goldstein, D.A. & Herlong, H.F. Predisposition to phenytoin hepatotoxicity assessed in vitro. N. Engl. J. Med. 305, 722-727 (1981). (Pubitemid 11062054)
    • (1981) New England Journal of Medicine , vol.305 , Issue.13 , pp. 722-727
    • Spielberg, S.P.1    Gordon, G.B.2    Blake, D.A.3
  • 27
    • 70349668597 scopus 로고    scopus 로고
    • In vitro testing for the diagnosis of anticonvulsant hypersensitivity syndrome: A systematic review
    • Elzagallaai, A.A., Knowles, S.R., Rieder, M.J., Bend, J.R., Shear, N.H. & Koren, G. In vitro testing for the diagnosis of anticonvulsant hypersensitivity syndrome: a systematic review. Mol. Diagn. Ther. 13, 313-330 (2009).
    • (2009) Mol. Diagn. Ther. , vol.13 , pp. 313-330
    • Elzagallaai, A.A.1    Knowles, S.R.2    Rieder, M.J.3    Bend, J.R.4    Shear, N.H.5    Koren, G.6
  • 28
    • 0034537765 scopus 로고    scopus 로고
    • A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes
    • DOI 10.1016/S0009-9120(00)00146-6, PII S0009912000001466
    • Neuman, M.G., Malkiewicz, I.M. & Shear, N.H. A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes. Clin. Biochem. 33, 517-524 (2000). (Pubitemid 32011860)
    • (2000) Clinical Biochemistry , vol.33 , Issue.7 , pp. 517-524
    • Neuman, M.G.1    Malkiewicz, I.M.2    Shear, N.H.3
  • 29
    • 78149401252 scopus 로고    scopus 로고
    • Predictive value of the lymphocyte toxicity assay in the diagnosis of drug hypersensitivity syndrome
    • Elzagallaai, A.A. et al. Predictive value of the lymphocyte toxicity assay in the diagnosis of drug hypersensitivity syndrome. Mol. Diagn. Ther. 14, 317-322 (2010).
    • (2010) Mol. Diagn. Ther. , vol.14 , pp. 317-322
    • Elzagallaai, A.A.1
  • 30
    • 84884754706 scopus 로고    scopus 로고
    • Platelet structure
    • (ed. Michelson, A.) Academic Press, Burlington, MA
    • White, J. Platelet structure. In: Platelets (ed. Michelson, A.) 45-74 (Academic Press, Burlington, MA; 2007).
    • (2007) Platelets , pp. 45-74
    • White, J.1
  • 31
    • 0001849290 scopus 로고    scopus 로고
    • Platelet preparation and estimation of functional responses
    • (eds. Watson, S., Authi, K.) Oxford University Press, Oxford, UK
    • McNicol, A. Platelet preparation and estimation of functional responses. In: Platelets (eds. Watson, S., Authi, K.) 1-26 (Oxford University Press, Oxford, UK, 1996).
    • (1996) Platelets , pp. 1-26
    • McNicol, A.1
  • 33
    • 36749058003 scopus 로고    scopus 로고
    • Defining a role for platelets in allergic inflammation
    • DOI 10.1042/BST0351104
    • P itchford, S.C. Defining a role for platelets in allergic inflammation. Biochem. Soc. Trans. 35, 1104-1108 (2007). (Pubitemid 350206439)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1104-1108
    • Pitchford, S.C.1
  • 35
    • 61549089703 scopus 로고    scopus 로고
    • Platelets play important roles in the late phase of the immediate hypersensitivity reaction
    • 587.e1
    • T amagawa-Mineoka, R., Katoh, N. & Kishimoto, S. Platelets play important roles in the late phase of the immediate hypersensitivity reaction. J. Allergy Clin. Immunol. 123, 581-7, 587.e1 (2009).
    • (2009) J. Allergy Clin. Immunol. , vol.123 , pp. 581-587
    • Tamagawa-Mineoka, R.1    Katoh, N.2    Kishimoto, S.3
  • 38
    • 77952867867 scopus 로고    scopus 로고
    • Approach to the patient with a drug hypersensitivity reactionsclinical perspectives
    • ( ed. Pichler, W.) Karger, Basel, Switzerland
    • Birchler, A. Approach to the patient with a drug hypersensitivity reactionsclinical perspectives. In: Drug Hypersensitivity ( ed. Pichler, W.) 352-365 (Karger, Basel, Switzerland, 2007).
    • (2007) Drug Hypersensitivity , pp. 352-365
    • Birchler, A.1
  • 39
    • 77953549920 scopus 로고    scopus 로고
    • Approach to the patient with drug allergy
    • xv
    • S chnyder, B. Approach to the patient with drug allergy. Med. Clin. North Am. 94, 665-79, xv (2010).
    • (2010) Med. Clin. North Am. , vol.94 , pp. 665-679
    • Schnyder, B.1
  • 40
    • 77949320495 scopus 로고    scopus 로고
    • Pharmacogenetics of idiosyncratic adverse drug reactions
    • P irmohamed, M. Pharmacogenetics of idiosyncratic adverse drug reactions. Handb. Exp. Pharmacol. 196, 477-491 (2010).
    • (2010) Handb. Exp. Pharmacol. , vol.196 , pp. 477-491
    • Pirmohamed, M.1


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