Lamotrigine-dextran conjugates-synthesis, characterization, and biological evaluation

Medicinal Chemistry Research

Volumn 20, Issue 5, 2011, Pages 595-600

  Pugazhendhy, S ^a   Shrivastava, Prabhat K ^a   Sinha, Saurabh K ^a   Shrivastava, Sushant K ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Anticonvulsant activity; Dextran; Hepatotoxicity; In vitro hydrolysis; Lamotrigine; Prodrug

Indexed keywords

ALDEHYDE; DEXTRAN; GLYCOCONJUGATE; IMINE; LAMOTRIGINE; LAMOTRIGINE DEXTRAN CONJUGATE; PERIODATE SODIUM; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG HYDROLYSIS; DRUG SAFETY; DRUG SCREENING; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; LIVER TOXICITY; MALE; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; SEIZURE; ULTRAVIOLET SPECTROSCOPY; VISCOMETER;

EID: 80052024668     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9355-9     Document Type: Article

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