Fatal progressive hepatic necrosis associated with lamotrigine treatment: A case report and literature review

Digestive Diseases and Sciences

Volumn 47, Issue 9, 2002, Pages 1921-1925

  Overstreet, Kerith ^a   Costanza, Christopher ^b   Behling, Cynthia ^a   Hassanin, Tarrek ^b   Masliah, Eliezer ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UCSD MEDICAL CENTER   (United States)

Author keywords

Drug; Hepatotoxin; Lamotrigine; Liver; Toxicity

Indexed keywords

ACETYLCYSTEINE; ALBUMIN; ALPHA TOCOPHEROL; CARNITINE; CHLORAL HYDRATE; GANCICLOVIR; HALOPERIDOL; LAMOTRIGINE; OLANZAPINE; PARACETAMOL; RISPERIDONE; TOPIRAMATE; TRAZODONE; URSODEOXYCHOLIC ACID; VITAMIN K GROUP;

ADULT; ARTICLE; AUTOPSY; CASE REPORT; CHILD; CHILL; CLINICAL FEATURE; DRUG INDUCED DISEASE; FEMALE; FEVER; HEPATIC ENCEPHALOPATHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INSOMNIA; LIVER BIOPSY; LIVER NECROSIS; MANIC DEPRESSIVE PSYCHOSIS; NAUSEA; PELVIS PAIN SYNDROME; PRIORITY JOURNAL; RASH; SUBSTANCE ABUSE; SYMPTOM; VOMITING;

ADULT; ANTICONVULSANTS; BIOPSY; BIPOLAR DISORDER; FATAL OUTCOME; FEMALE; HEPATITIS, TOXIC; HUMANS; LIVER; LIVER FAILURE; TRIAZINES;

EID: 0036715545     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019627618972     Document Type: Article

References (8)

1. Lamotrigine
2. Lamotrigine in children
3. Severe Hypersensitivity syndrome to lamotrigine confirmed by lymphocyte stimulation in vitro
4. Multisystem adverse reaction to lamotrigine
5. Fulminant hepatic failure induced by lamotrigine
6. Potential hepatotoxicity of lamotrigine
7. Acute hepatic failure in a child treated with lamotrigine
8. Multiorgan failure and disseminated intravascular coagulation in severe convulsive seizures