The proton translocation domain of cellular vacuolar ATPase provides a target for the treatment of influenza A virus infections

British Journal of Pharmacology

Volumn 164, Issue 2, 2011, Pages 344-357

  Müller, Konstantin H ^a   Kainov, Denis E ^a,g   El Bakkouri, Karim ^b   Saelens, Xavier ^c   De Brabander, Jef K ^d   Kittel, Christian ^e   Samm, Elisabeth ^f   Muller, Claude P ^a  

^a LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f Avir Green Hills Biotechnology AG   (Austria)

^g UNIVERSITY OF HELSINKI   (Finland)

Author keywords

archazolid B; bafilomycin A1; concanamycin A; H5N1; influenza A virus; pandemic H1N1; salicylihalamide A derivatives; saliphenylhalamide; v ATPase; v ATPase inhibitor

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE INHIBITOR; ANTIVIRUS AGENT; ARCHAZOLID B; BAFILOMYCIN A1; CONCANAMYCIN A; GREEN FLUORESCENT PROTEIN; OSELTAMIVIR; SALIPHENYLHALAMIDE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; CELL VACUOLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG CYTOTOXICITY; DRUG EFFECT; ENZYME BINDING; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA A; INFLUENZA VIRUS A; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PANDEMIC INFLUENZA; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TARGETING; PROTON TRANSPORT; VIRUS INHIBITION; VIRUS MUTATION; VIRUS RESISTANCE; VIRUS STRAIN; WILD TYPE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DOGS; ENZYME INHIBITORS; GREEN FLUORESCENT PROTEINS; INFLUENZA A VIRUS, H1N1 SUBTYPE; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; ORTHOMYXOVIRIDAE INFECTIONS; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS; VACUOLAR PROTON-TRANSLOCATING ATPASES; VIRUS REPLICATION;

EID: 80051966225     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01346.x     Document Type: Article

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