Mechanisms for the Establishment of Pregnancy in the Pig

Reproduction in Domestic Animals

Volumn 46, Issue SUPPL. 3, 2011, Pages 31-41

  Ziecik, Aj ^a   Waclawik, A ^a   Kaczmarek, Mm ^a   Blitek, A ^a   Jalali, B Moza ^a   Andronowska, A ^a  

^a INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTAGLANDIN;

ANIMAL; ANIMAL DISEASE; ARTIFICIAL INSEMINATION; BREEDING; FEMALE; FEMALE GENITAL SYSTEM; MALE; METABOLISM; PHYSIOLOGY; PREGNANCY; REVIEW; SPERM; SWINE;

ANIMALS; FEMALE; GENITALIA, FEMALE; INSEMINATION, ARTIFICIAL; MALE; PREGNANCY; PREGNANCY, ANIMAL; PROSTAGLANDINS; SEMEN; SWINE;

SUIDAE;

EID: 80051866971     PISSN: 09366768     EISSN: 14390531     Source Type: Journal    
DOI: 10.1111/j.1439-0531.2011.01843.x     Document Type: Review

References (122)

1. 2 on luteal function in cycling gilts. Prostaglandins 32, 291-299.
2. Almlid T, 1981: Does enhanced antigenicity of semen increase the litter size in pigs? J Anim Breed Genet 98, 1-10.
3. Ashworth MD, Ross JW, Hu J, White FJ, Stein DR, Desilva U, Johnson GA, Spencer TE, Geisert RD, 2006: Expression of porcine endometrial prostaglandin synthase during the estrous cycle and early pregnancy, and following endocrine disruption of pregnancy. Biol Reprod 74, 1007-1015.
4. Bauersachs S, Blum H, Mallok S, Wenigerkind H, Rief S, Prelle K, Wolf E, 2003: Regulation of ipsilateral and contralateral bovine oviduct epithelial cell function in the postovulation period: a transcriptomics approach. Biol Reprod 68, 783-795.
5. 2α by the uterine endometrium. Prostaglandins 14, 397-401.
6. Bazer FW, Spencer TE, Johnson GA, Burghardt RC, Wu G, 2009: Comparative aspects of implantation. Reproduction 138, 195-209.
7. Bischof RJ, Brandon MR, Lee CS, 1995: Cellular immune responses in the pig uterus during pregnancy. J Reprod Immunol 29, 161-178.
8. Blitek A, Ziecik AJ, 2006a: Role of tumour necrosis factor alpha in stimulation of prostaglandins F(2alpha) and E(2) release by cultured porcine endometrial cells. Reprod Domest Anim 41, 562-567.
9. Blitek A, Waclawik A, Kaczmarek MM, Stadejek T, Pejsak Z, Ziecik AJ, 2006b: Expression of cyclooxygenase-1 and -2 in the porcine endometrium during the oestrous cycle and early pregnancy. Reprod Domest Anim 41, 251-257.
10. 2 release and cyclooxygenase-2 expression in cultured porcine endometrial stromal cells. Reprod Biol 7, 73-88.
11. Blitek A, Kaczmarek MM, Kiewisz J, Ziecik AJ, 2010a: Endometrial and conceptus expression of HoxA10, transforming growth factor β1, leukemia inhibitory factor, and prostaglandin H synthase-2 in early pregnant pigs with gonadotropin-induced estrus. Domest Anim Endocrinol 38, 222-234.
12. Blitek A, Kiewisz J, Waclawik A, Kaczmarek MM, Ziecik AJ, 2010b: Effect of steroids on HOXA10 mRNA and protein expression and prostaglandin production in the porcine endometrium. J. Reprod. Dev. 56, 643-648.
13. Blitek A, Morawska E, Kiewisz J, Ziecik AJ, 2011: Effect of conceptus secretions on HOXA 10 and PTGS2 gene expression, and PGE2 release in co-cultured luminal epithelial and stromal cells of the porcine endometrium at the time of early implantation. Theriogenology DOI: 10.1016/j.theriogenology.2011.05.002.
14. Bowen JA, Bazer FW, Burghardt RC, 1996: Spatial and temporal analyses of integrin and Muc-1 expression in porcine uterine epithelium and trophectoderm in vivo. Biol Reprod 55, 1098-1106.
15. Buhi WC, Alvarez IM, 2003: Identification, characterization and localization of three proteins expressed by the porcine oviduct. Theriogenology 60, 225-238.
16. Burghardt RC, Johnson GA, Jaeger LA, Ka H, Garlow JE, Spencer TE, Bazer FW, 2002: Integrins and extracellular matrix proteins at the maternal-fetal interface in domestic animals. Cells Tissues Organs 171, 202-217.
17. Calvete JJ, Ensslin M, Mburu J, Iborra A, Martínez P, Adermann K, Waberski D, Sanz L, Töpfer-Petersen E, Weitze KF, Einarsson S, Rodríguez-Martínez H, 1997: Monoclonal antibodies against boar sperm zona pellucida-binding protein AWN-1. Characterization of a continuous antigenic determinant and immunolocalization of AWN epitopes in inseminated sows. Biol Reprod 57, 735-742.
18. Chow JF, Lee KF, Chan STH, Yeung WSB, 2001: Quantification of transforming growth factor β-1 (TGFβ-1) mRNA expression in mouse preimplantation embryos and determination of TGFβ-1 receptor (type I and type II) expression in mouse embryos and reproductive tract. Mol Hum Reprod 7, 1047-1056.
19. 2. Prostaglandins 47, 61-75.
20. Conley AJ, Ford SP, 1989: Direct luteotrophic effect of oestradiol-17β on pig corpora lutea. J Reprod Fertil 87, 125-131.
21. Daftary GS, Taylor HS, 2006: Endocrine regulators of HOX genes. Endocr Rev 27, 331-355.
22. Dantzer V, 1985: Electron microscopy of the initial stages of placentation in the pig. Anat Embryol (Berl) 172, 281-293.
23. Davis DL, Blair RM, 1993: Studies of uterine secretions and products of primary cultures of endometrial cells in pigs. J Reprod Fertil Suppl 48, 143-155.
24. Downing SJ, Maguiness SD, Tay JI, Watson A, Leese HJ, 2002: Effect of platelet-activating factor on electro-physiology of the human Fallopian tube: early mediation of embryo-maternal dialogue. Reproduction 124, 523-529.
25. Dziuk PJ, 1985: Effect of migration, distribution and spacing of pig embryos on pregnancy and fetal survival. J Reprod Fertil 33, 57-63.
26. Einarsson S, Jones B, Larsson K, Viring S, 1980: Distribution of small- and medium-sized molecules within the genital tract of artificially inseminated gilts. J Reprod Fertil 59, 453-457.
27. Emond V, Fortier MA, Murphy BD, Lambert RD, 1998: Prostaglandin E2 regulates both interleukin-2 and granulocyte-macrophage colony-stimulating factor gene expression in bovine lymphocytes. Biol Reprod 58, 143-151.
28. Erikson DW, Burghardt RC, Bayless KJ, Johnson GA, 2009: Secreted phosphoprotein 1 (SPP1, osteopontin) binds to integrin alphavbeta6 on porcine trophectoderm cells and integrin alphavbeta3 on uterine luminal epithelial cells, and promotes trophectoderm cell adhesion and migration. Biol Reprod 81, 814-825.
29. Fazeli A, Affara NA, Hubank M, Holt WV, 2004: Sperm-induced modification of the oviductal gene expression profile after natural insemination in mice. Biol Reprod 71, 60-65.
30. Finetti F, Solito R, Morbidelli L, Giachetti A, Ziche M, Donnini S, 2008: Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1. J Biol Chem 283, 2139-2146.
31. Ford SP, Magness RR, Farley DB, Van Orden DE, 1982: Local and systemic effects of intrauterine estradiol-17 beta on luteal function of nonpregnant sows. J Anim Sci 55, 657-664.
32. Franczak A, Kurowicka B, Oponowicz A, Petroff BK, Kotwica G, 2006: The effect of progesterone on oxytocin-stimulated intracellular mobilization of Ca2+ and prostaglandin E2 and F2alpha secretion from porcine myometrial cells. Prostaglandins Other Lipid Mediat 81, 37-44.
33. Franczak A, Zmijewska A, Kurowicka B, Wojciechowicz B, Kotwica G, 2010: Interleukin 1β-induced synthesis and secretion of prostaglandin E(2) in the porcine uterus during various periods of pregnancy and the estrous cycle. J Physiol Pharmacol 61, 733-742.
34. Gabler C, Einspanier A, Schams D, 1999: Expression of vascular endothelial growth factor (VEGF) and its corresponding receptors (flt-1 and flk-1) in the bovine oviduct. Mol Reprod Dev 53, 376-383.
35. Gadsby JE, Lovdal JA, Britt JH, Fitz TA, 1993: Prostaglandin F2α receptor concentrations in corpora lutea of cycling, pregnant, and pseudopregnant pigs. Biol Reprod 49, 604-608.
36. Garlow JE, Ka H, Johnson GA, Burghardt RC, Jaeger LA, Bazer FW, 2002: Analysis of osteopontin at the maternal-placental interface in pigs. Biol Reprod 66, 718-725.
37. Garverick HA, Polge C, Flint AP, 1982: Oestradiol administration raises luteal LH receptor levels in intact and hysterectomized pigs. J Reprod Fertil 66, 371-377.
38. Geisert RD, Zavy MT, Moffatt RJ, Blair RM, Yellin T, 1990: Embryonic steroids and the establishment of pregnancy in pigs. J Reprod Fertil Suppl 40, 293-305.
39. Geisert RD, Brenner RM, Moffatt J, Harney JP, Yellin T, Bazer FW, 1993: Changes in oestrogen receptor protein, mRNA expression and localization in the endometrium of cyclic and pregnant gilts. Reprod Fertil Dev 5, 247-260.
40. Geisert RD, Pratt TN, Bazer FW, Mayes JS, Watson GH, 1994: Immunocytochemical localization and changes in endometrial progestin receptor protein during the porcine oestrous cycle and early pregnancy. Reprod Fertil Dev 6, 749-760.
41. Geisert RD, Ross JW, Ahworth MD, White FJ, Johnson GA, DeSilva U, 2006: Maternal recognition of pregnancy signal or endocrine disruptor: the two faces of oestrogen during establishment of pregnancy in the pig. In: Ashworth CJ, Kraeling RR (eds), Control of Pig Reproduction VII. University Press Nottingham, Nottingham, pp. 131-145.
42. Georgiou AS, Sostaric E, Wong CH, Snijders APL, Wright PC, Moore HD, Fazeli A, 2005: Gametes alter the oviductal secretory proteome. Mol Cell Proteomics 4, 1785-1796.
43. Georgiou AS, Sniders APL, Sostaric E, Aflatoonian R, Vazquez JL, Vazquez JM, Roca J, Martinez EA, Wright PC, Fazeli A, 2007: Modulation of the oviductal environment by gametes. J Proteome Res 6, 4656-4666.
44. Giguère A, Girard CL, Lambert R, Laforest JP, Matte JJ, 2000: Reproductive performance and uterine prostaglandin secretion in gilts conditioned with dead semen and receiving dietary supplements of folic acid. Can J Anim Sci 80, 467-472.
45. Gupta A, Dekaney ChM, Bazer FW, Madrigal MM, Jaeger LA, 1998a: Beta Transforming growth factors (TGFβ) at the porcine conceptus maternal interface. Part II: uterine TGFβ bioactivity and expression of immunoreactive TGFβs (TGFβ1, TGFβ2, and TGFβ3) and their receptors (type I and type II). Biol Reprod 59, 911-917.
46. Gupta A, Ing NH, Bazer FW, Bustamante LS, Jaeger LA, 1998b: Beta Transforming growth factors (TGFβ) at the porcine conceptus maternal interface. Part I: expression of TGFβ1, TGFβ2, and TGFβ3 messenger ribonucleic acids. Biol Reprod 59, 905-910.
47. Hunt JS, Chen HL, Miller L, 1996: Tumor necrosis factors: pivotal components of pregnancy? Biol Reprod 54, 554-562.
48. Hunter RHF, 1974: Chronological and cytological details of fertilization and early embryonic development in the domestic pig, Sus scrofa. Anat Rec 178, 169-185.
49. Jaeger LA, Spiegel AK, Ing NH, Johnson GA, Bazer FW, Burghardt RC, 2005: Functional effects of transforming growth factor β on adhesive properties of porcine trophectoderm. Endocrinology 146, 3933-3942.
50. Jiwakanon J, Berg M, Persson E, Fossum C, Dalin AM, 2010: Cytokine expression in the gilt oviduct: effects of seminal plasma, spermatozoa and extender after insemination. Anim Reprod Sci 119, 244-257.
51. Joyce MM, Burghardt RC, Geisert RD, Burghardt JR, Hooper RN, Ross JW, Ashworth MD, Johnson GA, 2007: Pig conceptuses secrete estrogen and interferons to differentially regulate uterine STAT1 in a temporal and cell type-specific manner. Endocrinology 148, 4420-4431.
52. Ka H, Jaeger LA, Johnson GA, Spencer TE, Bazer FW, 2001: Keratinocyte growth factor expression is up-regulated by estrogen in porcine uterine endometrium and it functions in trophectodermal cell proliferation and differentiation. Endocrinology 142, 2303-2310.
53. Ka H, Al-Ramadan S, Johnson GA, Burghardt RC, Spencer TE, Jaeger LA, Bazer FW, 2007: Regulation of fibroblast growth factor 7 expression in the pig uterine endometrium by progesterone and estradiol. Biol Reprod 77, 172-180.
54. 2. Mol Cell Endocrinol 291, 33-41.
55. Kaczmarek MM, Blitek A, Filant J, Ziecik AJ, 2009a: Seminal plasma regulates prostaglandin synthesis enzymes in the porcine endometrium. 8th International Conference on Pig Reproduction, Banff, Canada, June 2009. Conference proceedings 131.
56. Kaczmarek MM, Krawczynski K, Blitek A, Ziecik AJ, 2009b: Seminal plasma affects angiogenesis in the porcine endometrium. Reprod Dom Anim 44, 110.
57. Kaczmarek MM, Kiewisz J, Schams D, Ziecik AJ, 2009c: Expression of VEGF-receptor system in conceptus during peri-implantation period and endometrial and luteal expression of soluble VEGFR-1 in the pig. Theriogenology 71, 1298-1306.
58. Kaczmarek MM, Krawczynski K, Blitek A, Kiewisz J, Schams D, Ziecik AJ, 2010: Seminal plasma affects prostaglandin synthesis in the porcine oviduct. Theriogenology 74, 1207-1220.
59. Kaminska K, Wasielak M, Bogacka I, Blitek M, Bogacki M, 2008: Quantitative expression of lysophosphatidic acid receptor 3 gene in porcine endometrium during the periimplantation period and estrous cycle. Prostaglandins Other Lipid Mediat 85, 26-32.
60. Kennedy TG, Gillio-Meina C, Phang SH, 2007: Prostaglandins and the initiation of blastocyst implantation and decidualization. Reproduction 134, 635-643.
61. Keys JL, King GJ, Kennedy TG, 1986: Increased uterine vascular permeability at the time of embryonic attachment in the pig. Biol Reprod 34, 405-411.
62. King GJ, 1988: Reduction in uterine intra-epithelial lymphocytes during early gestation in pigs. J Reprod Immunol 14, 41-46.
63. 2 and tumor necrosis factor α on the VEGF-receptor system expression in cultured porcine luteal cells. Mol Reprod Dev 75, 1558-1566.
64. Kowalski AA, Graddy LG, Vale-Cruz DS, Choi I, Katzenellenbogen BS, Simmen FA, Simmen RC, 2002: Molecular cloning of porcine estrogen receptor-beta complementary DNAs and developmental expression in periimplantation embryos. Biol Reprod 66, 760-769.
65. Kraeling RR, Rampacek GB, Fiorello NA, 1985: Inhibition of pregnancy with indomethacin in mature gilts and prepuberal gilts induced to ovulate. Biol Reprod 32, 105-110.
66. Krzymowski T, Stefanczyk-Krzymowska S, 2004: The oestrous cycle and early pregnancy - a new concept of local endocrine regulation. Vet J 168, 285-296.
67. Krzymowski T, Kotwica J, Okrasa S, Doboszynska T, Ziecik A, 1978: Luteal function in sows after unilateral PGF2α infusion into the anterior uterine on different days of the oestrous cycle. J Reprod Fertil 54, 21-27.
68. Laforest JP, King GJ, 1992: Structural and functional aspects of porcine endometrial capillaries on days 13 and 15 after oestrus or mating. J Reprod Fertil 94, 269-277.
69. Lai YM, Wang SH, Lee CL, Lee JD, Huang HY, Chang FH, Lee JF, Soong YK, 1996: Insulin-like growth factor-binding proteins produced by Vero cells, human oviductal cells and human endometrial cells, and the role of insulin-like growth factor-binding protein-3 in mouse embryo co-culture system. Hum Reprod 11, 1281-1286.
70. Massuto DA, Kneese EC, Johnson GA, Burghardt RC, Hooper RN, Ing NH, Jaeger LA, 2010: Transforming growth factor beta (TGFβ) signaling is activated during porcine implantation: proposed role for latency-associated peptide interactions with integrins at the conceptus-maternal interface. Reproduction 139, 465-478.
71. Mathew DJ, Sellner EM, Green JC, Okamura CS, Anderson LL, Lucy MC, Geisert RD, 2011: Uterine progesterone receptor expression, conceptus development, and ovarian function in pigs treated with RU 486 during early pregnancy. Biol Reprod 84, 130-139.
72. McCauley TC, Buhi WC, Wu GM, Mao J, Caamano JN, Didion BA, Day BN, 2003: Oviduct-specific glycoprotein modulates sperm-zona binding and improves efficiency of porcine fertilization in vitro. Biol Reprod 69, 828-834.
73. Modrić T, Kowalski AA, Green ML, Simmen RC, Simmen FA, 2000: Pregnancy-dependent expression of leukaemia inhibitory factor (LIF), LIF receptor-beta and interleukin-6 (IL-6) messenger ribonucleic acids in the porcine female reproductive tract. Placenta 21, 345-353.
74. Moeljono MP, Thatcher WW, Bazer FW, Frank M, Owens LJ, Wilcox CJ, 1977: A study of prostaglandin F2alpha as the luteolysin in swine: II Characterization and comparison of prostaglandin F, estrogens and progestin concentrations in utero-ovarian vein plasma of nonpregnant and pregnant gilts. Prostaglandins 14, 543-555.
75. Murray FA, Grifo AP Jr, Parker CF, 1983: Increased litter size in gilts by intrauterine infusion of seminal and sperm antigens before breeding. J Anim Sci 56, 895-900.
76. O'Leary S, Jasper MJ, Warnes GM, Armstrong DT, Robertson SA, 2004: Seminal plasma regulates endometrial cytokine expression, leukocyte recruitment and embryo development in the pig. Reproduction 128, 237-247.
77. Østrup E, Bauersachs S, Blum H, Wolf E, Hyttel P, 2010: Differential endometrial gene expression in pregnant and nonpregnant sows. Biol Reprod 83, 277-285.
78. Parhar RS, Yagel S, Lala PK, 1989: PGE2-mediated immunosuppression by first trimester human decidual cells blocks activation of maternal leukocytes in the deciduas with potential anti-trophoblast activity. Cell Immunol 120, 61-74.
79. Paria BC, Reese J, Das SK, Dey SK, 2002: Deciphering the cross-talk of implantation: advances and challenges. Science 296, 2185-2188.
80. Pope WF, Maurer RR, Stormshak F, 1982: Intrauterine migration of the porcine embryo-interaction of embryo, uterine flushings and indomethacin on myometrial function in vitro. J Anim Sci 55, 1169-1178.
81. Rhodes M, Brendemuhl JH, Hansen PJ, 2006: Litter characteristics of gilts artificially inseminated with transforming growth factor-beta. Am J Reprod Immunol 56, 153-156.
82. Robertson SA, 2007: Seminal fluid signaling in the female reproductive tract: lessons from rodents and pigs. J Anim Sci 85(E. Suppl.), E36-E44.
83. Robertson SA, Mau VJ, Tremellen KP, Seamark RF, 1996: Role of high molecular weight seminal vesicle proteins in eliciting the uterine inflammatory response to semen in mice. J Reprod Fertil 107, 265-277.
84. Rodríguez-Martínez H, Einarsson S, 1985: Influence of prostaglandins on the spontaneous motility of pig oviducts. Anim Reprod Sci 8, 259-279.
85. Ross JW, Malayer JR, Ritchey JW, Geisert RD, 2003: Characterization of the interleukin-1beta system during porcine trophoblastic elongation and early placental attachment. Biol Reprod 69, 1251-1259.
86. Rozeboom KJ, Troedsson MH, Crabo BG, 1998: Characterization of uterine leukocyte infiltration in gilts after artificial insemination. J Reprod Fertil 114, 195-199.
87. Rozeboom KJ, Troedsson MH, Molitor TW, Crabo BG, 1999: The effect of spermatozoa and seminal plasma on leukocyte migration into the uterus of gilts. J Anim Sci 77, 2201-2206.
88. Rozeboom KJ, Rocha-Chavez G, Troedsson MH, 2001: Inhibition of neutrophil chemotaxis by pig seminal plasma in vitro: a potential method for modulating post-breeding inflammation in sows. Reproduction 121, 567-572.
89. Segi E, Haraguchi K, Sugimoto Y, Tsuji M, Tsunekawa H, Tamba S, Tsuboi K, Tanaka S, Ichikawa A, 2003: Expression of messenger RNA for prostaglandin E receptor subtypes EP4/EP2 and cyclooxygenase isozymes in mouse periovulatory follicles and oviducts during superovulation. Biol Reprod 68, 804-811.
90. Seo H, Kim M, Choi Y, Lee CK, Ka H, 2008: Analysis of lysophosphatidic acid (LPA) receptor and LPA-induced endometrial prostaglandin-endoperoxide synthase 2 expression in the porcine uterus. Endocrinology 149, 6166-6175.
91. Short RV, 1969: Implantation and the maternal recognition of pregnancy. In: Wolstenholme GEW, O'Connor M (eds), Ciba Foundation Symposium on Foetal Autonomy. J. and A. Churchil, London, pp. 2-26.
92. Spencer TE, Johnson GA, Burghardt RC, Bazer FW, 2004: Progesterone and placental hormone actions on the uterus: insights from domestic animals. Biol Reprod 71, 2-10.
93. Stefanczyk-Krzymowska S, Krzymowski T, 2002: Local adjustment of blood and lymph circulation in the hormonal regulation of reproduction in female pigs-facts, conclusions and suggestions for future research. Reprod Biol 2, 115-132.
94. Stefanczyk-Krzymowska S, Wasowska B, Chlopek J, Gilun P, Grzegorzewski W, Radomski M, 2006: Retrograde and local destination transfer of uterine prostaglandin E2 in early pregnant sow and its physiological consequences. Prostaglandins Other Lipid Mediat 81, 71-79.
95. Szafrańska B, Ziecik A, 1989: Active and passive immunization against luteinizing hormone in pigs. Acta Physiol Hung 74, 253-258.
96. Tayade C, Fang Y, Hilchie D, Croy BA, 2007: Lymphocyte contributions to altered endometrial angiogenesis during early and midgestation fetal loss. J Leukocyte Biol 82, 877-886.
97. Taylor U, Zerbe H, Seyfert HM, Rath D, Baulain U, Langner KF, Schuberth HJ, 2009a: Porcine spermatozoa inhibit post-breeding cytokine induction in uterine epithelial cells in vivo. Anim Reprod Sci 115, 279-289.
98. Taylor U, Schuberth HJ, Rath D, Michelmann HW, Sauter-Louis C, Zerbe H, 2009b: Influence of inseminate components on porcine leucocyte migration in vitro and in vivo after pre- and post-ovulatory insemination. Reprod Domest Anim 44, 180-188.
99. Tremellen KP, Seamark RF, Robertson SA, 1998: Seminal transforming growth factor beta1 stimulates granulocyte-macrophage colony-stimulating factor production and inflammatory cell recruitment in the murine uterus. Biol Reprod 58, 1217-1225.
100. Uzumcu M, Braileanu GT, Carnahan KG, Ludwig TE, Mirando MA, 1998: Oxytocin-stimulated phosphoinositide hydrolysis and prostaglandin F secretion by luminal epithelial, glandular and stromal cells from pig endometrium. I. Response of cyclic pigs on day 16 postestrus. Biol Reprod 59, 1259-1265.
101. Vallet JL, Christenson RK, Trout WE, Klemcke HG, 1998: Conceptus, progesterone, and breed effects on uterine protein secretion in swine. J Anim Sci 76, 2657-2670.
102. Waberski D, Dohring A, Ardon F, Ritter N, Zerbe H, Schuberth H-J, Hewicker-Trautwein M, Weitze KF, Hunter RHF, 2006: Physiological routes from intra-uterine seminal contents to advancement of ovulation. Acta Vet Scand 48, 13.
103. Waclawik A, Ziecik AJ, 2007: Differential expression of prostaglandin (PG) synthesis enzymes in conceptus during peri-implantation period and endometrial expression of carbonyl reductase/PG 9-ketoreductase in the pig. J Endocrinol 194, 499-510.
104. Waclawik A, Rivero-Muller A, Blitek A, Kaczmarek MM, Brokken LJ, Watanabe K, Rahman NA, Ziecik AJ, 2006: Molecular cloning and spatiotemporal expression of prostaglandin F synthase and microsomal prostaglandin E synthase-1 in porcine endometrium. Endocrinology 147, 210-221.
105. Waclawik A, Kaczmarek MM, Kowalczyk AE, Bogacki M, Ziecik AJ, 2008a: Expression of prostaglandin synthesis pathway enzymes in the porcine corpus luteum during the estrous cycle and early pregnancy. Theriogenology 70, 145-152.
106. Waclawik A, Blitek A, Jabbour HN, Ziecik AJ, 2008b: The expression and regulation of EP2 and EP4 in the pig endometrium. Abstract Book, The Society for Reproduction and Fertility Conference, Edinburgh, UK, 29th June - 1st July, pp. 56.
107. Waclawik A, Blitek A, Kaczmarek MM, Kiewisz J, Ziecik AJ, 2009a: Antiluteolytic mechanisms and the establishment of pregnancy in the pig. In: Rodriguez-Martinez H, Vallet JL, Ziecik AJ (eds), Control of Pig Reproduction VIII. Nottingham University Press, Nottingham, pp. 307-320.
108. Waclawik A, Jabbour HN, Blitek A, Ziecik AJ, 2009b: Estradiol-17beta, prostaglandin E2 (PGE2), and the PGE2 receptor are involved in PGE2 positive feedback loop in the porcine endometrium. Endocrinology 150, 3823-3832.
109. Waclawik A, Blitek A, Ziecik AJ, 2010: Oxytocin and tumor necrosis factor alpha stimulate expression of prostaglandin E2 synthase and secretion of prostaglandin E2 by luminal epithelial cells of the porcine endometrium during early pregnancy. Reproduction 140, 613-622.
110. Wånggren K, Lalitkumar PG, Stavreus-Evers A, Ståbi B, Gemzell-Danielsson K, 2006: Prostaglandin E2 and F2alpha receptors in the human Fallopian tube before and after mifepristone treatment. Mol Hum Reprod 12, 577-585.
111. Wasielak M, Glowacz M, Kaminska K, Waclawik A, Bogacki M, 2008: The influence of embryo presence on prostaglandin synthesis and prostaglandin E2 and F2α content in corpora lutea during periimplantation period in the pig. Mol Reprod Dev 75, 1208-1216.
112. Watanabe K, 2002: Prostaglandin F synthase. Prostaglandins Other Lipid Mediat. 68-69, 401-407.
113. Watson AJ, Westhusin ME, Winger QA, 1999: IGF paracrine and autocrine interactions between conceptus and oviduct. J Reprod Fertil Suppl 54, 303-315.
114. White FJ, Kimball EM, Wyman G, Stein DR, Ross JW, Ashworth MD, Geisert RD, 2009: Estrogen and interleukin-1beta regulation of trophinin, osteopontin, cyclooxygenase-1, cyclooxygenase-2, and interleukin-1beta system in the porcine uterus. In: Rodriguez-Martinez H, Vallet JL, Ziecik AJ (eds), Control of Pig Reproduction VIII. Nottingham University Press, Nottingham, pp. 203-204.
115. Whyte A, Binns RM, 1994: Adhesion molecule expression and infiltrating maternal leucocyte phenotypes during blastocyst implantation in the pig. Cell Biol Int 18, 759-766.
116. Ye X, Hama K, Contos JJ, Anliker B, Inoue A, Skinner MK, Suzuki H, Amano T, Kennedy G, Arai H, Aoki J, Chun J, 2005: LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing. Nature 435, 104-108.
117. Yeung WS, Lau EY, Chan AY, Ho PC, 1996: The production of interleukin-1 alpha immunoreactivity by human oviductal cells in the coculture system. J Asist Reprod Genet 13, 772-775.
118. Yu Z, Gordon JR, Kendall J, Thacker PA, 1998: Elevation in tumour necrosis factor-alpha (TNF-alpha) messenger RNA levels in the uterus of pregnant gilts after oestrogen treatment. Anim Reprod Sci 50, 57-67.
119. Yun SM, Choi KC, Kim IH, An BS, Lee GS, Hong EJ, Oh GT, Jeung EB, 2004: Dominant expression of porcine Calbindin-D9k in the uterus during a luteal phase. Mol Reprod Dev 67, 251-256.
120. Zavy MT, Bazer FW, Thatcher WW, Wilcox CJ, 1980: A study of prostaglandin F2 alpha as the luteolysin in swine: V. Comparison of prostaglandin F, progestins, estrone and estradiol in uterine flushings from pregnant and nonpregnant gilts. Prostaglandins 20, 837-851.
121. Ziecik A, Shaw HJ, Flint APF, 1980: Luteal receptors during the estrous cycle and early pregnancy in the pig. J Reprod Fertil 60, 129-137.
122. Zorrilla LM, Irvin MS, Gadsby JE, 2009: Protein kinase C isoforms in the porcine corpus luteum: temporal and spatial expression patterns. Domest Anim Endocrinol 36, 173-185.