Estradiol-17β, prostaglandin E2 (PGE2), and the PGE2 receptor are involved in PGE2 positive feedback loop in the porcine endometrium

Endocrinology

Volumn 150, Issue 8, 2009, Pages 3823-3832

  Waclawik, Agnieszka ^a   Jabbour, Henry N ^b   Blitek, Agnieszka ^a   Ziecik, Adam J ^a  

^a INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; CARBONYL REDUCTASE; CYCLIC AMP; ESTRADIOL; GW 627368X; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN D2 11 KETOREDUCTASE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG; CYCLOOXYGENASE 2; ESTROGEN; ISOMERASE; OXYTOCIC AGENT; PROSTAGLANDIN E SYNTHASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOMETRIUM; ESTRUS CYCLE; FEEDBACK SYSTEM; FIRST TRIMESTER PREGNANCY; GILT (SWINE); NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECT; ENZYME IMMUNOASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; METABOLISM; POLYMERASE CHAIN REACTION; PREGNANCY; SWINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CYCLIC AMP; CYCLOOXYGENASE 2; DINOPROST; DINOPROSTONE; ENDOMETRIUM; ESTRADIOL; ESTROGENS; ESTROUS CYCLE; FEMALE; IMMUNOENZYME TECHNIQUES; IMMUNOHISTOCHEMISTRY; INTRAMOLECULAR OXIDOREDUCTASES; OXYTOCICS; POLYMERASE CHAIN REACTION; PREGNANCY; RECEPTORS, PROSTAGLANDIN E; SWINE;

EID: 67651160584     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1499     Document Type: Article

References (50)

1. Perry JS, Heap RB, Amoroso EC 1973 Steroid hormone production by pig blastocysts. Nature 245:45-47
2. Bazer FW, Thatcher WW 1977 Theory of maternal recognition of pregnancy in swine based on estrogen controlled endocrine versus exocrine secretion of prostaglandin F2α by the uterine endometrium. Prostaglandins 14:397-400
3. Ford SP, Magness RR, Farley DB, Van Orden DE 1982 Local and systemic effects of intrauterine estradiol-17β on luteal function of nonpregnant sows. J Anim Sci 55:657-664
4. Spencer TE, Bazer FW 2004 Conceptus signals for establishment and maintenance of pregnancy. Reprod Biol Endocrinol 2:49
5. Geisert RD, Thatcher WW, Roberts RM, Bazer FW 1982 Establishment of pregnancy in the pig. III. Endometrial secretory response to estradiol valerate administered on day 11 of the estrous cycle. Biol Reprod 27:957-965
6. Conley AJ, Ford SP 1989 Direct luteotrophic effect of oestradiol-17β on pig corpora lutea. J Reprod Fertil 87:125-131
7. Christenson LK, Ford SP 1995 Comparison of prostaglandin F2α-induced luteolysis in early pregnant and estrogen-treated 'pseudopregnant' gilts. Anim Reprod Sci 38:239-249
8. Akinlosotu BA, Diehl JR, Gimenez T 1986 Sparing effects of intrauterine treatment with prostaglandin E2 on luteal function in cycling gilts. Prostaglandins 32:291-299
9. Christenson LK, Farley DB, Anderson LH, Ford SP 1994 Luteal maintenance during early pregnancy in the pig role for prostaglandin E2. Prostaglandins 47:61-75
10. Weems CW, Weems YS, Randel RD 2006 Prostaglandins and reproduction in female farm animals. Vet J 171:206-228
11. Kennedy TG, Gillio-Meina C, Phang SH 2007 Prostaglandins and the initiation of blastocyst implantation and decidualization. Reproduction 134:635-643
12. Kraeling RR, Rampacek GB, Fiorello NA 1985 Inhibition of pregnancy with indomethacin in mature gilts and prepuberal gilts induced to ovulate. Biol Reprod 32:105-110
13. Smith WL, Garavito RM, De Witt DL 1996 Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem 271:33157-33160
14. Waclawik A, Rivero-Muller A, Blitek A, Kaczmarek MM, Brokken LJ, Watanabe K, Rahman NA, Ziecik AJ 2006 Molecular cloning and spatiotemporal expression of prostaglandin F synthase and microsomal prostaglandin E synthase-1 in porcine endometrium. Endocrinology 147:210-221
15. Schieber A, Frank RW, Ghisla S 1992 Purification and properties of prostaglandin 9-ketoreductase from pig and human kidney. Identity with human carbonyl reductase. Eur J Biochem 206:491-502
16. Ghosh D, Sawicki M, Pletnev V, Erman M, Ohno S, Nakajin S, Duax WL 2001 Porcine carbonyl reductase. structural basis for a functional monomer in short chain dehydrogenases/reductases. J Biol Chem 276 18457-18463
17. Waclawik A, Ziecik AJ 2007 Differential expression of prostaglandin (PG) synthesis enzymes in conceptus during peri-implantation period and endometrial expression of carbonyl reductase/PG 9-ketoreductase in the pig. J Endocrinol 194:499-510
18. Ashworth MD, Ross JW, Hu J, White FJ, Stein DR, Desilva U, Johnson GA, Spencer TE, Geisert RD 2006 Expression of porcine endometrial prostaglandin synthase during the estrous cycle and early pregnancy, and following endocrine disruption of pregnancy. Biol Reprod 74:1007-1015
19. Blitek A, Waclawik A, Kaczmarek MM, Stadejek T, Pejsak Z, Ziecik AJ 2006 Expression of cyclooxygenase-1 and -2 in the porcine endometrium during the oestrous cycle and early pregnancy. Reprod Domest Anim 41: 251-257
20. Geisert RD, Renegar RH, Thatcher WW, Roberts RM, Bazer FW 1982 Establishment of pregnancy in the pig. I. Interrelationships between preimplantation development of the pig blastocyst and uterine endometrial secretions. Biol Reprod 27:925-939
21. Narumiya S, Sugimoto Y, Ushikubi F 1999 Prostanoid receptors: structures, properties, and functions. Physiol Rev 79:1193-1226
22. 2 receptors in pseudopregnant rat endometrium. Biol Reprod 62:1515-1525
23. Fortier MA, Boulet AP, DugréFJ, Lambert RD 1990 Local alteration in adenylate cyclase activity and stimulation response at implantation site in rabbit endometrium during early pregnancy. Biol Reprod 42:106-113
24. Tanaka N, Miyazaki K, Tashiro H, Mizutani H, Okamura H 1993 Changes in adenylyl cyclase activity in human endometrium during the menstrual cycle and in human decidua during pregnancy. J Reprod Fertil 98:33-39
25. Kobayashi T, Narumiya S 2002 Function of prostanoid receptors: studies on knockout mice. Prostaglandins Other Lipid Mediat 68-69:557-573
26. Kennedy TG, Keys JL, King GJ 1986 Endometrial prostaglandin E2-binding sites in the pig characterization and changes during the estrous cycle and early pregnancy. Biol Reprod 35:624-632
27. Tysseling KA, Uzumcu M, Hoagland TA, Crain RC, Mirando MA 1996 The role of phosphoinositide-derived second messengers in oxytocin-stimulated prostaglandin F2α release from endometrium of pigs. Domest Anim Endocrinol 13:411-420
28. Parent J, Fortier MA 2005 Expression and contribution of three different isoforms of prostaglandin E synthase in the bovine endometrium. Biol Reprod 73:36-44
29. Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
30. Waclawik A, Kaczmarek MM, Kowalczyk AE, Bogacki M, Ziecik AJ 2008 Expression of prostaglandin synthesis pathway enzymes in the porcine corpus luteum during the oestrous cycle and early pregnancy. Theriogenology 70: 145-152
31. Blitek A, Ziecik AJ 2004 Prostaglandins F and E secretion by porcine epithelial and stromal endometrial cells on different days of the oestrous cycle. Reprod Domest Anim 39:340-346
32. Wilson RJ, Giblin GM, Roomans S, Rhodes SA, Cartwright KA, Shield VJ, Brown J, Wise A, Chowdhury J, Pritchard S, Coote J, Noel LS, Kenakin T, Burns-Kurtis CL, Morrison V, Gray DW, Giles H 2006 GW627368X ((N-{2-[4-(4,9-diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl) phenyl]acetyl} benzene sulphonamide): a novel, potent and selective prostanoid EP4 receptor antagonist. Br J Pharmacol 148:326-339
33. Krzymowski T, Kotwica J, Stefanczyk-Krzymowska S 1990 Uterine and ovarian countercurrent pathways in the control of ovarian function in the pig. J Reprod Fertil Suppl 40:179-191
34. Fischer HE, Bazer FW, Fields MJ 1985 Steroid metabolism by endometrial and conceptus tissues during early pregnancy and pseudopregnancy in gilts. J Reprod Fertil 75:69-78
35. Pusateri AE, Rothschild MF, Warner CM, Ford SP 1990 Changes in morphology, cell number, cell size and cellular estrogen content of individual littermate pig conceptuses on days 9 to 13 of gestation. J Anim Sci 68:3727-3735
36. Geisert RD, Yelich JV 1997 Regulation of conceptus development and attachment in pigs. J Reprod Fertil Suppl 52:133-149
37. Flood PF 1974 Steroid-metabolizing enzymes in the early pig conceptus and in the related endometrium. J Endocrinol 63:413-414
38. White FJ, Ross JW, Joyce MM, Geisert RD, Burghardt RC, Johnson GA 2005 Steroid regulation of cell specific secreted phosphoprotein 1 (osteopontin) expression in the pregnant porcine uterus. Biol Reprod 73:1294-1301
39. Beaver CJ, Murdoch WJ 1992 Ovarian and uterine prostaglandin E2-9-ketoreductase activity in cyclic and pregnant ewes. Prostaglandins 44:37-42
40. 2 reductase effect of oxytocin and interferon-τ. Biol Reprod 62:125-131
41. Schlegel W, Krü ger S, Korte K 1984 Purification of prostaglandin E2-9-oxoreductase from human decidua vera. FEBS Lett 171:141-144
42. Ing NH 2005 Steroid hormones regulate gene expression posttranscriptionally by altering the stabilities of messenger RNAs. Biol Reprod 72:1290-1296
43. Geisert RD, Ross JW, Ashworth MD, White FJ, Johnson GA, De Silva U 2006 Maternal recognition of pregnancy signal or endocrine disruptor: the two faces of oestrogen during establishment of pregnancy in the pig. Soc Reprod Fertil Suppl 62:131-145
44. Weems YS, Lammoglia MA, Lewis AW, Randel RD, Sasser RG, Morita I, Weems CW 1999 PGE2 induces its own secretion in vitro by bovine 270-day placenta but not by 200-day placenta. Prostaglandins Other Lipid Mediat 57:189-205
45. 2 in endometrial adenocarcinoma: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors. Br J Cancer 85:1023-1031
46. 2 synthesis are up-regulated in carcinomas of the cervix: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors. J Clin Endocrinol Metab 86:2243-2249
47. Arosh JA, Banu SK, Kimmins S, Chapdelaine P, Maclaren LA, Fortier MA 2004 Effect of interferon-τ on prostaglandin biosynthesis, transport, and signaling at the time of maternal recognition of pregnancy in cattle: evidence of polycrine actions of prostaglandin E2. Endocrinology 145:5280 - 5293
48. Hamilton GS, Kennedy TG 1994 Uterine vascular changes after unilateral intrauterine infusion of indomethacin and prostaglandin E2 to rats sensitized for the decidual cell reaction. Biol Reprod 50:757-764
49. 2 and EP2/EP4 receptors in human nonpregnant endometrium across the menstrual cycle. J Clin Endocrinol Metab 86:4453-4459
50. Arosh JA, Banu SK, Chapdelaine P, Emond V, Kim JJ, MacLaren LA, Fortier MA 2003 Molecular cloning and characterization of bovine prostaglandin E2 receptors EP2 and EP4: expression and regulation in endometrium and myometrium during the estrous cycle and early pregnancy. Endocrinology 144: 3076-3091