Yeast dynamically modify their environment to achieve better mating efficiency

Science Signaling

Volumn 4, Issue 186, 2011, Pages

  Jin, Meng ^a   Errede, Beverly ^a   Behar, Marcelo ^b   Mather, Will ^c   Nayak, Sujata ^c   Hasty, Jeff ^c   Dohlman, Henrik G ^a   Elston, Timothy C ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAR1 PROTEASE; FUNGAL ENZYME; MATING HORMONE ALPHA FACTOR; PROTEINASE; UNCLASSIFIED DRUG; ASPARTIC PROTEINASE; BAR1 PROTEIN, S CEREVISIAE; PEPTIDE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CELL ELONGATION; CHEMOTROPIC GROWTH; COMPUTER SIMULATION; CONTROLLED STUDY; ENZYME RELEASE; FUNGAL CELL; FUNGAL STRAIN; FUNGUS GROWTH; MATING SUCCESS; MICROFLUIDICS; NONHUMAN; ORGANISMAL INTERACTION; PRESSURE GRADIENT; PRIORITY JOURNAL; GENETICS; MATING FACTOR; METABOLISM; PROTEIN DEGRADATION; SACCHAROMYCES CEREVISIAE; SECRETION;

SACCHAROMYCETALES;

ASPARTIC ACID ENDOPEPTIDASES; PEPTIDES; PROTEOLYSIS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 80051857711     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2001763     Document Type: Article

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21. Funding: This work was supported by NIH grants GM-079271 (M.J. and T.C.E.), GM-084071 (B.E.), GM-073180 (H.G.D.), and GM-079333 (J.H.). Author contributions: M.J. and B.E. devised the mating assays and performed the experiments. M.J., M.B., and T.C.E. devised the computational investigations.M.J. and M.B. developed the computational platform for simulating chemotropic growth and M.J. performed the simulations.S.N., W.M., and J.H. devised themicrofluidic experiments, and S.N. and W.M. performed the gradient experiments. M.J., B.E., H.G.D., and T.C.E. wrote the manuscript. Simulation availability: http://www.med.unc.edu/pharm/elstonlab/ResearchSignalTransduction. html.