TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Mitra, Aninda ^a   Kalayarasan, Srinivasan ^a   Gupta, Vijay ^a,b   Radha, Vegesna ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FORSKOLIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR C3G; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; PERVANADATE; PHOSPHOTYROSINE; SOMATOMEDIN; TYROSINE; UNCLASSIFIED DRUG; VANADIC ACID; MUTANT PROTEIN; PROTEIN TYROSINE KINASE; PTPN2 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING ASSAY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; ENZYME INACTIVATION; ENZYME SUBSTRATE; GOLGI COMPLEX; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEUROBLASTOMA; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE BINDING SITE; ONCOGENE SRC; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; CELL DIFFERENTIATION; CELL STRAIN HEK293; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; METABOLISM; NEURITE; PATHOLOGY; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

CELL DIFFERENTIATION; CELL LINE, TUMOR; FORSKOLIN; GOLGI APPARATUS; GUANINE NUCLEOTIDE-RELEASING FACTOR 2; HEK293 CELLS; HUMANS; MUTANT PROTEINS; NEURITES; NEUROBLASTOMA; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 2; SRC-FAMILY KINASES; STRUCTURE-ACTIVITY RELATIONSHIP; VANADATES;

EID: 80051840811     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023681     Document Type: Article

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