Activation of spinal extracellular signal-regulated kinases (ERK) 1/2 is associated with the development of visceral hyperalgesia of the bladder

Pain

Volumn 152, Issue 9, 2011, Pages 2117-2124

  Lai, H Henry ^a,b   Qiu, Chang Shen ^a,c   Crock, Lara W ^c   Morales, Maria Elena P ^c   Ness, Timothy J ^d   Gereau IV, Robert W ^c  

^a WASHINGTON UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Central sensitization; ERK signaling; Inflammatory pain; Urinary bladder; Visceral pain; Visceromotor response

Indexed keywords

CYCLOPHOSPHAMIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER DISTENSION; BLADDER HYPERALGESIA; BRAIN COMMISSURE; CHEMICAL CYSTITIS; CONTROLLED STUDY; CYSTALGIA; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXPERIMENTAL MOUSE; FEMALE; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; LUMBAR SPINAL CORD; MOUSE; NOCICEPTION; NONHUMAN; PARASYMPATHETIC NERVE; PRIORITY JOURNAL; SACRAL SPINAL CORD; SPINAL CORD DORSAL HORN; SPINAL PARASYMPATHETIC NUCLEUS; VISCERAL PAIN; VISCEROMOTOR RESPONSE;

ANIMALS; ENZYME ACTIVATION; FEMALE; HYPERALGESIA; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; SPINAL CORD; URINARY BLADDER; VISCERAL PAIN;

EID: 80051795833     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2011.05.017     Document Type: Article

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