Effects of inorganic mercury on reproductive performance of mice

Food and Chemical Toxicology

Volumn 42, Issue 4, 2004, Pages 571-577

  Khan, Abu T ^a,b   Atkinson, Alfonza ^a   Graham, Thomas C ^a   Thompson, Sherylee J ^a   Ali, Salwa ^a   Shireen, Kaniz F ^a,b  

^a TUSKEGEE UNIVERSITY   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Analysis of variance; ANOVA; Maximum tolerated dose; MC; Mercuric chloride; Methyl mercuric chloride; Mice; MMC; MTD; Oral; Reproductive toxicity

Indexed keywords

MERCURIC CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; CONTROLLED STUDY; DRUG EXPOSURE; FEMALE; FEMALE FERTILITY; HISTOPHOTOMETRY; LACTATION; LITTER SIZE; MALE; MALE FERTILITY; MATING SYSTEM; MOUSE; NIDATION; NONHUMAN; ORGAN WEIGHT; PREGNANCY; REPRODUCTIVE TOXICITY; SPECIES COMPARISON; TARGET CELL DESTRUCTION;

ADMINISTRATION, ORAL; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; FERTILITY; LONGEVITY; MALE; MATERNAL EXPOSURE; MERCURIC CHLORIDE; MICE; MICE, INBRED C57BL; ORGAN SIZE; OVARY; PATERNAL EXPOSURE; PREGNANCY; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 1542376195     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2003.10.018     Document Type: Article

References (22)

1. Atkinson A., Thompson S.J., Khan A.T., Graham T.C., Ali S., Shannon C., Clarke O., Upchurch L. Assessment of a two-generation reproductive and fertility study of mercuric chloride in rats. Food and Chemical Toxicolgy. 39:2001;73-84.
2. Baranshi B., Szmczyk I. Effects of mercury vapor upon reproductive function of female white rats. Medycyna pracy. 24:1973;248.
3. Berlin M. Mercury. Friberg L., Nordberg G.F., Vouk V.B., Kessler X. Handbook on the Toxicology of Metals, 2nd ed., Vol, Specific Metals. 1986;387-445 Elsever, Amsterdam.
4. Bishop J.B., Morris R.W., Seely J.C., Hughes L. A, Cain, K. T, Generoso, W. M., Alterations in reproductive patterns of female mice exposed to xenobiotics. Fundamental and Applied Toxicology. 21:1997;8-14.
5. Burbacher T.M., Mohammed M.K., Mottett N.K. Methylmercury effects on reproduction and offspring size at birth. Reproductive Toxicology. 1:1988;267-278.
6. Chapin R.E., Morrisey R.E., Gulati D.K. Hope, E, Barnes, L. H, Russell, S. A, Kennedy, S. R., Are mouse strains differentially susceptible to reproductive toxicity of ethylene glycol monomethyl ether? A study of three strains. Fundamental and Applied Toxicology. 40:1993;191-204.
7. Chey S.W., Keong W.M., Min S.Y. Changes in tissue glutathione and mercury concentrations in rats following mercuric chloride injection through the hepatic portal vein. Bulletin of Environmental Contamination and Toxicology. 42:1989;942-948.
8. Cordier S., Deplan F., Mandereau L. Paternal exposure to mercury and spontaneous abortions. British Journal of Industrial Medicine. 48(6):1991;375-381.
9. Fuyuta F.T., Hirata S. Embryonic effects of methylmercuric chloride administrated to mice and rats during organogenesis. Teratology. 18:1978;353-366.
10. Gale T.F. Embryonic effects of different routes of administration of mercuric acetate on the hamster. Environmental Research. 8:1974;207-213.
11. Germani M.S., Zolleer W.H. Vapor-phase concentrations of arsenic, selenium bromine, iodine and mercury in the stack of a coal-fired power plant. Environmental Science and Technology. 22(9):1988;1079-1085.
12. Hatch W.R., Ott W.L. Determination of submicrogram quantities of mercury by atomic absorption Spectrophotometry. Analytical Chemistry. 40:1968;2085-2087.
13. Hughes J.A., Annau Z. Postnatal behavioral effects in mice after prenatal exposure to methylmercury. Pharmacology, biochemistry, and behavior 4. 1976;385-391.
14. Inouye M., Kajiwara Y. Developmental disturbance of the fetal brain in guinea-pigs caused by methylmercury. Archive of Toxicology. 62:1988;15-21.
15. Jonker D., Woutersen R.A., Van Bladeren P.J. Sub acute (4-wk) oral toxicity of a combination of four nephrotoxins in rats. comparison with the toxicity of the individual compounds Food and Chemical Toxicology. 31:1993;125-136.
16. Khan A.T., Atkinson A., Graham T.C., Thompson S.J., Datiri B., Ali S., Webster J.E., Ferguson J. A, Effects of 14 days exposure of mice to mercuric chloride on body weight and tissue distribution of mercury. The Toxicologist. 36:1997;278.
17. Khera K.S. Reproductive capability of male rats and mice treated with methyl mercury. Toxicology and Applied Pharmacology. 24:1973;167-177.
18. Oser B.L., Oser M. Nutritional studies on rats on diets containing high levels of partial ester emulsifiers. II. Reproduction and lactation. Journal of Nutrition. 60:1966;489.
19. Nishiyama S., Taguchi T., Onosaka S. Induction of zincthionein by estradiol and protective effects of inorganic mercury-induced renal toxicity. Biochemical. Pharmacology. 36:1987;3387-3391.
20. NTP, 1993. Technical Report on the Toxicology and Carcinogenesis Studies of Mercuric Chloride in F344 Rats and B6C3F1 Mice (CAS No. 7487-94-7, NIH Publication No. 93-3139).
21. Sikorski R., Juszkiewicz T., Paszkowski J.K. Women in dental surgeries. Reproductive hazards in occupational exposure to metallic mercury International archives of occupational and environmental health. 59:1987;551-557.
22. Suter K.E. Studies on the dominant-lethal and fertility effects of heavy metal compounds methylmercuric hydroxide, mercuric chloride and cadmium chloride in male and female mice. Mutation Research. 30:1975;365-374.