Occurrence of identical NOTCH1 mutation in non-twinned sisters with T-cell acute lymphoblastic leukemia

Leukemia

Volumn 25, Issue 8, 2011, Pages 1368-1370

  Mansur, M B ^a   Ford, A M ^b   Van Delft, F W ^b   Gonzalez, D ^b   Emerenciano, M ^a   Maia, R C ^a   Greaves, M ^b   Pombo De Oliveira, M S ^a  

^a INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HOX PROTEIN; HOX11 PROTEIN; HOX11L2 PROTEIN; LMO1 PROTEIN; LMO2 PROTEIN; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN P53; TRANSCRIPTION FACTOR TAL1; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; CANCER RISK; CELL PROLIFERATION; CHILDHOOD CANCER; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; LETTER; LEUKEMIA REMISSION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 80051793833     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.96     Document Type: Letter

References (9)

1. Draper GJ, Sanders BM, Lennox EL, Brownbill PA. Patterns of childhood cancer among siblings. Br J Cancer 1996;74:152-158. (Pubitemid 26231994)
2. Hemminki K, Sundquist J, Bermejo JL. How common is familial cancer? Ann Oncol 2008;19:163-167.
3. Papaemmanuil E, Hosking FJ, Vijayakrishnan J, Price A, Olver B, Sheridan E et al. Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat Genet 2009;41:1006-1010.
4. Grabher C, von Boehmer H, Look AT. Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. Nat Rev Cancer 2006;6:347-359.
5. Weng AP, Ferrando AA, Lee W, Morris IV JP, Silverman LB, Sanchez-Irizarry C et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004;306:269-271. (Pubitemid 39336870)
6. Eguchi-Ishimae M, Eguchi M, Kempski H, Greaves M. NOTCH1 mutation can be an early, prenatal genetic event in T-ALL. Blood 2008;111:376-378.
7. Chen J, Jette C, Kanki JP, Aster JC, Look AT, Griffin JD. NOTCH1-induced T-cell leukemia in transgenic zebrafish. Leukemia 2007;21:462-471.
8. O'Neil J, Calvo J, McKenna K, Krishnamoorthy V, Aster JC, Bassing CH et al. Activating Notch1 mutations in mouse models of T-ALL. Blood 2006;107:781-785. (Pubitemid 43076406)
9. Greaves MF, Maia AT, Wiemels JL, Ford AM. Leukemia in twins: lessons in natural history. Blood 2003;102:2321-2333. (Pubitemid 37193565)