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Volumn 14, Issue 5, 2011, Pages 497-503

Commensal bacteria: The link between IBS and IBD?

Author keywords

antibiotics; Crohn's disease; inflammatory bowel disease; irritable bowel syndrome; microbiota; probiotics; ulcerative colitis

Indexed keywords

ANTIBIOTIC AGENT; PLACEBO; PREBIOTIC AGENT; PROBIOTIC AGENT; RIFAXIMIN;

EID: 80051790402     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0b013e328348c033     Document Type: Review
Times cited : (7)

References (66)
  • 2
    • 70449513263 scopus 로고    scopus 로고
    • An evidence-based approach to the management of irritable bowel syndrome in Europe
    • Quigley EMM, Bergmann J-F, Bytzer P, et al. An evidence-based approach to the management of irritable bowel syndrome in Europe. Eur J Gastroenterol Hepatol 2007;19(Suppl 1):S1-S37.
    • (2007) Eur J Gastroenterol Hepatol , vol.19 , Issue.1 SUPPL.
    • Quigley, E.M.M.1    Bergmann, J.-F.2    Bytzer, P.3
  • 3
    • 77954002828 scopus 로고    scopus 로고
    • Asian consensus on irritable bowel syndrome
    • Gwee KA, Bak YT, Ghoshal UC, et al. Asian consensus on irritable bowel syndrome. J Gastroenterol Hepatol 2010;25:1189-1205. An important survey of the prevalence, presenting features and management of IBS in Asia which reveals some interesting deviations from Western experience in terms of demographics and symptomatology.
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 1189-1205
    • Gwee, K.A.1    Bak, Y.T.2    Ghoshal, U.C.3
  • 7
    • 70349566856 scopus 로고    scopus 로고
    • Postinfectious irritable bowel syndrome
    • Thabane M, Marshall JK. Postinfectious irritable bowel syndrome. World J Gastroenterol 2009;15:3591-3596.
    • (2009) World J Gastroenterol , vol.15 , pp. 3591-3596
    • Thabane, M.1    Marshall, J.K.2
  • 8
    • 65449165950 scopus 로고    scopus 로고
    • Postinfectious irritable bowel syndrome
    • Spiller R, Garsed K. Postinfectious irritable bowel syndrome. Gastroenterology 2009;136:1979-1988.
    • (2009) Gastroenterology , vol.136 , pp. 1979-1988
    • Spiller, R.1    Garsed, K.2
  • 9
    • 77949833947 scopus 로고    scopus 로고
    • Genetic risk factors for postinfectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis
    • Villani AC, Lemire M, Thabane M, et al. Genetic risk factors for postinfectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis. Gastroenterology 2010;138:1502-1513. Identifies genetic factors that seem to predispose to PI-IBS and link its development to deficits in the epithelial barrier and the host immune response.
    • (2010) Gastroenterology , vol.138 , pp. 1502-1513
    • Villani, A.C.1    Lemire, M.2    Thabane, M.3
  • 10
    • 77953274740 scopus 로고    scopus 로고
    • Bacteria, genetics and irritable bowel syndrome (IBS)
    • Craig OF, Quigley EMM. Bacteria, genetics and irritable bowel syndrome (IBS). Expert Rev Gastroenterol 2010;4:271-276.
    • (2010) Expert Rev Gastroenterol , vol.4 , pp. 271-276
    • Craig, O.F.1    Quigley, E.M.M.2
  • 11
    • 66949151443 scopus 로고    scopus 로고
    • The vexed relationship between Clostridium difficile and inflammatory bowel disease: An assessment of carriage in an outpatient setting among patients in remission
    • Clayton EM, Rea MC, Shanahan F, et al. The vexed relationship between Clostridium difficile and inflammatory bowel disease: an assessment of carriage in an outpatient setting among patients in remission. Am J Gastroenterol 2009;104:1162-1169.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1162-1169
    • Clayton, E.M.1    Rea, M.C.2    Shanahan, F.3
  • 12
    • 67650973314 scopus 로고    scopus 로고
    • Increased short-and longterm risk of inflammatory bowel disease after salmonella or campylobacter gastroenteritis
    • Gradel KO, Nielsen HL, Schønheyder HC, et al. Increased short-and longterm risk of inflammatory bowel disease after salmonella or campylobacter gastroenteritis. Gastroenterology 2009;137:495-501.
    • (2009) Gastroenterology , vol.137 , pp. 495-501
    • Gradel, K.O.1    Nielsen, H.L.2    Schønheyder, H.C.3
  • 13
    • 78149264493 scopus 로고    scopus 로고
    • Do patients with functional gastrointestinal disorders have an altered flora?
    • Quigley EMM. Do patients with functional gastrointestinal disorders have an altered flora? Ther Adv Gastroenterol 2009;2(Suppl 1):S23-S30.
    • (2009) Ther Adv Gastroenterol , vol.2 , Issue.1 SUPPL.
    • Quigley, E.M.M.1
  • 14
    • 77949263115 scopus 로고    scopus 로고
    • Pathogenesis of IBS: Role of inflammation, immunity and neuroimmune interactions
    • Ohman L, Simren M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nat Rev Gastroenterol Hepatol 2010;7:163-173.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 163-173
    • Ohman, L.1    Simren, M.2
  • 15
    • 79751499345 scopus 로고    scopus 로고
    • Differential expression of Toll-like receptors (TLRs) in patients with irritable bowel syndrome
    • Brint EK, MacSharry J, Fanning A, et al. Differential expression of Toll-like receptors (TLRs) in patients with irritable bowel syndrome. Am J Gastroenterol 2011;106:329-336. By demonstrating up-regulation of genes encoding forTLR-4, as well as increased expression of TLR-4 in the colonic epithelium, provides the much-needed link between Gram-negative bacteria and IBS, suggesting that these organisms may be responsible for the enhanced inflammatory response seen in IBS.
    • (2011) Am J Gastroenterol , vol.106 , pp. 329-336
    • Brint, E.K.1    MacSharry, J.2    Fanning, A.3
  • 16
    • 59749092589 scopus 로고    scopus 로고
    • Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome
    • Langhorst J, Junge A, Rueffer A, et al. Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome. Am J Gastroenterol 2009;104:404-410.
    • (2009) Am J Gastroenterol , vol.104 , pp. 404-410
    • Langhorst, J.1    Junge, A.2    Rueffer, A.3
  • 17
    • 79953704539 scopus 로고    scopus 로고
    • Altered peripheral toll-like receptor responses in the irritable bowel syndrome
    • McKernan DP, Gaszner G, Quigley EM, et al. Altered peripheral toll-like receptor responses in the irritable bowel syndrome. Aliment Pharmacol Ther 2011;33:1045-1052.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 1045-1052
    • McKernan, D.P.1    Gaszner, G.2    Quigley, E.M.3
  • 18
    • 80051788176 scopus 로고    scopus 로고
    • Basic and translational understandings of microbial recognition by toll-like receptors in the intestine
    • Rhee SH. Basic and translational understandings of microbial recognition by toll-like receptors in the intestine. J Neurogastroenterol Motil 2011;17:28-34.
    • (2011) J Neurogastroenterol Motil , vol.17 , pp. 28-34
    • Rhee, S.H.1
  • 19
    • 79952397377 scopus 로고    scopus 로고
    • The enteric microbiota in the pathogenesis and management of constipation
    • Quigley EM. The enteric microbiota in the pathogenesis and management of constipation. Best Pract Res Clin Gastroenterol 2011;25:119-126. An up-to-date review of the status of antibacterial, microbiota-modifying and antiinflammatory approaches in constipation.
    • (2011) Best Pract Res Clin Gastroenterol , vol.25 , pp. 119-126
    • Quigley, E.M.1
  • 20
    • 33644910165 scopus 로고    scopus 로고
    • Germs, gas and the gut; the evolving role of the enteric flora in IBS
    • DOI 10.1111/j.1572-0241.2006.00445.x
    • Quigley EM. Germs, gas and the gut; the evolving role of the enteric flora in IBS. Am J Gastroenterol 2006;101:334-335. (Pubitemid 43381676)
    • (2006) American Journal of Gastroenterology , vol.101 , Issue.2 , pp. 334-335
    • Quigley, E.M.M.1
  • 21
    • 77950670562 scopus 로고    scopus 로고
    • Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome
    • Tana C, Umesaki Y, Imaoka A, et al. Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome. Neurogastroenterol Motil 2010;22:512-519.
    • (2010) Neurogastroenterol Motil , vol.22 , pp. 512-519
    • Tana, C.1    Umesaki, Y.2    Imaoka, A.3
  • 22
    • 79957601426 scopus 로고    scopus 로고
    • Microbial community and metabolomic comparison of irritable bowel syndrome faeces
    • Epub ahead of print
    • Ponnusamy K, Choi JN, Kim J, et al. Microbial community and metabolomic comparison of irritable bowel syndrome faeces. J Med Microbiol 2011 [Epub ahead of print].
    • (2011) J Med Microbiol
    • Ponnusamy, K.1    Choi, J.N.2    Kim, J.3
  • 23
    • 80051785670 scopus 로고    scopus 로고
    • Luminal and mucosal-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome
    • Carroll IM, Chang YH, Park J, et al. Luminal and mucosal-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome. Gut Pathog 2010;2:19.
    • (2010) Gut Pathog , vol.2 , pp. 19
    • Carroll, I.M.1    Chang, Y.H.2    Park, J.3
  • 24
    • 78149341679 scopus 로고    scopus 로고
    • Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota
    • Noor SO, Ridgway K, Scovell L, et al. Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota. BMC Gastroenterol 2010;10:134.
    • (2010) BMC Gastroenterol , vol.10 , pp. 134
    • Noor, S.O.1    Ridgway, K.2    Scovell, L.3
  • 25
    • 79251495453 scopus 로고    scopus 로고
    • Molecular analysis of faecal and duodenal samples reveals significantly higher prevalence and numbers of Pseudomonas aeruginosa in irritable bowel syndrome
    • Kerckhoffs AP, Ben-Amor K, Samsom M, et al. Molecular analysis of faecal and duodenal samples reveals significantly higher prevalence and numbers of Pseudomonas aeruginosa in irritable bowel syndrome. J Med Microbiol 2011;60:236-245.
    • (2011) J Med Microbiol , vol.60 , pp. 236-245
    • Kerckhoffs, A.P.1    Ben-Amor, K.2    Samsom, M.3
  • 26
    • 77957591287 scopus 로고    scopus 로고
    • Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome
    • Malinen E, Krogius-Kurikka L, Lyra A, et al. Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome. World J Gastroenterol 2010;16:4532-4540.
    • (2010) World J Gastroenterol , vol.16 , pp. 4532-4540
    • Malinen, E.1    Krogius-Kurikka, L.2    Lyra, A.3
  • 27
    • 74549185684 scopus 로고    scopus 로고
    • Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers
    • Krogius-Kurikka L, Lyra A, Malinen E, et al. Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers. BMC Gastroenterol 2009;9:95.
    • (2009) BMC Gastroenterol , vol.9 , pp. 95
    • Krogius-Kurikka, L.1    Lyra, A.2    Malinen, E.3
  • 28
    • 74549200558 scopus 로고    scopus 로고
    • Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification
    • Lyra A, Rinttila T, Nikkila J, et al. Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification. World J Gastroenterol 2009;15:5936-5945.
    • (2009) World J Gastroenterol , vol.15 , pp. 5936-5945
    • Lyra, A.1    Rinttila, T.2    Nikkila, J.3
  • 29
    • 76849116160 scopus 로고    scopus 로고
    • A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome
    • Codling C, O'Mahony L, Shanahan F, et al. A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome. Dig DisSci 2010;55:392-397.
    • (2010) Dig DisSci , vol.55 , pp. 392-397
    • Codling, C.1    O'Mahony, L.2    Shanahan, F.3
  • 30
    • 67651252736 scopus 로고    scopus 로고
    • Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients
    • Kerckhoffs AP, Samsom M, van der Rest ME, et al. Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients. World J Gastroenterol 2009;15:2887-2892.
    • (2009) World J Gastroenterol , vol.15 , pp. 2887-2892
    • Kerckhoffs, A.P.1    Samsom, M.2    Van Der Rest, M.E.3
  • 31
    • 77950673152 scopus 로고    scopus 로고
    • Altered intestinal microbiota in irritable bowel syndrome
    • Lee KJ, Tack J. Altered intestinal microbiota in irritable bowel syndrome. Neurogastroenterol Motil 2010;22:493-498.
    • (2010) Neurogastroenterol Motil , vol.22 , pp. 493-498
    • Lee, K.J.1    Tack, J.2
  • 32
    • 77952512325 scopus 로고    scopus 로고
    • Intestinal dysbiosis in irritable bowel syndrome: Etiological factor or epiphenomenon?
    • Cremon C, Carini G, De Giorgio R, et al. Intestinal dysbiosis in irritable bowel syndrome: etiological factor or epiphenomenon? Expert Rev Mol Diagn 2010;10:389-393. A critical review of the microbiota in IBS.
    • (2010) Expert Rev Mol Diagn , vol.10 , pp. 389-393
    • Cremon, C.1    Carini, G.2    De Giorgio, R.3
  • 34
    • 79851512688 scopus 로고    scopus 로고
    • Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial overgrowth in patients with IBS
    • Yu D, Cheeseman F, Vanner S. Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial overgrowth in patients with IBS. Gut 2011;60:334-340.
    • (2011) Gut , vol.60 , pp. 334-340
    • Yu, D.1    Cheeseman, F.2    Vanner, S.3
  • 35
    • 70449710320 scopus 로고    scopus 로고
    • Small intestinal bacterial overgrowth in irritable bowel syndrome: Systematic review and meta-analysis
    • Ford AC, Spiegel BM, Talley NJ, Moayyedi P. Small intestinal bacterial overgrowth in irritable bowel syndrome: systematic review and meta-analysis. Clin Gastroenterol Hepatol 2009;7:1279-1286.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 1279-1286
    • Ford, A.C.1    Spiegel, B.M.2    Talley, N.J.3    Moayyedi, P.4
  • 36
    • 79957514424 scopus 로고    scopus 로고
    • Questioning the bacterial overgrowth hypothesis of irritable bowel syndrome: An epidemiologic and evolutionary perspective
    • Spiegel BM. Questioning the bacterial overgrowth hypothesis of irritable bowel syndrome: an epidemiologic and evolutionary perspective. Clin Gastroenterol Hepatol 2011 [Epub ahead of print]. A thoughtful, insightful and critical review of the role of SIBO in IBS.
    • (2011) Clin Gastroenterol Hepatol
    • Spiegel, B.M.1
  • 37
    • 38649115342 scopus 로고    scopus 로고
    • Microbial Influences in Inflammatory Bowel Diseases
    • DOI 10.1053/j.gastro.2007.11.059, PII S0016508507021579
    • Sartor RB. Microbial influences in inflammatory bowel disease. Gastroenterology 2008;134:577-594. (Pubitemid 351173057)
    • (2008) Gastroenterology , vol.134 , Issue.2 , pp. 577-594
    • Sartor, R.B.1
  • 38
    • 78649693004 scopus 로고    scopus 로고
    • Genetics and environmental interactions shape the intestinal microbiome to promote inflammatory bowel disease versus mucosal homeostasis
    • Sartor RB. Genetics and environmental interactions shape the intestinal microbiome to promote inflammatory bowel disease versus mucosal homeostasis. Gastroenterology 2010;139:181 6-1819. A concise review of interactions between the microbiota, genetics and the environment in Crohn's disease.
    • (2010) Gastroenterology , vol.139 , pp. 1816-1819
    • Sartor, R.B.1
  • 39
    • 79953748870 scopus 로고    scopus 로고
    • Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives
    • Joossens M, Huys G, Cnockaert M, et al. Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives. Gut 2011;60:631-637. One of the largest studies, to date, of the microbiota in Crohn's disease which compared Crohn's patients, not just with healthy controls, but also with unaffected relatives and, by revealing different patterns of dysbiosis in the patients and their unaffected relatives, suggests a role for the microbiota independent of diet and genetic background in this form of IBD.
    • (2011) Gut , vol.60 , pp. 631-637
    • Joossens, M.1    Huys, G.2    Cnockaert, M.3
  • 40
    • 78649686679 scopus 로고    scopus 로고
    • A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes
    • Willing BP, Dicksved J, Halfvarson J, et al. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology 2010;139:1844-1854. A detailed examination of the microbiota in Crohn's, ulcerative colitis and control individuals demonstrating, not only difference between Crohn's and ulcerative colitis and controls, but also differences between those with ileal and colonic Crohn's disease.
    • (2010) Gastroenterology , vol.139 , pp. 1844-1854
    • Willing, B.P.1    Dicksved, J.2    Halfvarson, J.3
  • 41
    • 78650099360 scopus 로고    scopus 로고
    • Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases
    • Frank DN, Robertson CE, Hamm CM, et al. Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases. Inflamm Bowel Dis 2011;17:179-184.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 179-184
    • Frank, D.N.1    Robertson, C.E.2    Hamm, C.M.3
  • 42
    • 78650973052 scopus 로고    scopus 로고
    • High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and noninflamed regions of the intestine in inflammatory bowel disease
    • Walker AW, Sanderson JD, Churcher C, et al. High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and noninflamed regions of the intestine in inflammatory bowel disease. BMC Microbiol 2011;11:7. Raises the possibility that microbial changes in IBD may be the consequence rather than the cause of the inflammatory process.
    • (2011) BMC Microbiol , vol.11 , pp. 7
    • Walker, A.W.1    Sanderson, J.D.2    Churcher, C.3
  • 43
    • 79951868908 scopus 로고    scopus 로고
    • Key questions to guide a better understanding of host-commensal microbiota interactions in intestinal inflammation
    • Sartor RB. Key questions to guide a better understanding of host-commensal microbiota interactions in intestinal inflammation. Mucosal Immunol 2011;4:127-132. Raises many of the issues and challenges that will need to be addressed in future studies of the role of the microbiota in inflammatory disease processes in the gastrointestinal tract.
    • (2011) Mucosal Immunol , vol.4 , pp. 127-132
    • Sartor, R.B.1
  • 44
    • 66249129571 scopus 로고    scopus 로고
    • Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease
    • Willing B, Halfvarson J, Dicksved J, et al. Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflamm Bowel Dis 2009;15:653-660.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 653-660
    • Willing, B.1    Halfvarson, J.2    Dicksved, J.3
  • 45
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an antiinflammatory commensal bacterium identified by gut microbiota analysis of Crohn's disease patients
    • Sokol H, Pigneur B, Watterlot L, et al. Faecalibacterium prausnitzii is an antiinflammatory commensal bacterium identified by gut microbiota analysis of Crohn's disease patients. Proc Natl Acad Sci USA 2008;105:16731-16736.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3
  • 46
    • 78649622569 scopus 로고    scopus 로고
    • Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray
    • Kang S, Denman SE, Morrison M, et al. Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray. Inflamm Bowel Dis 2010;16:2034-2042.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 2034-2042
    • Kang, S.1    Denman, S.E.2    Morrison, M.3
  • 47
    • 80051786272 scopus 로고    scopus 로고
    • Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease
    • Ng SC, Benjamin JL, McCarthy NE, et al. Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease. Inflamm Bowel Dis 2010 [Epub ahead of print].
    • (2010) Inflamm Bowel Dis
    • Ng, S.C.1    Benjamin, J.L.2    McCarthy, N.E.3
  • 48
    • 79958261709 scopus 로고    scopus 로고
    • The bowel microbiota and inflammatory bowel diseases
    • Tannock GW. The bowel microbiota and inflammatory bowel diseases. Int J Inflamm 2010;2010:954051. A thorough review of the pitfalls that have beset and the challenges that lie ahead for studies of the microbiota in IBD; many of these issues are also relevant to IBS.
    • (2010) Int J Inflamm , vol.2010 , pp. 954051
    • Tannock, G.W.1
  • 49
    • 77955419649 scopus 로고    scopus 로고
    • Irritable bowel syndrome-type symptoms in patients with inflammatory bowel disease: A real association or reflection of occult inflammation?
    • Keohane J, O'Mahony C, O'Mahony L, et al. Irritable bowel syndrome-type symptoms in patients with inflammatory bowel disease: a real association or reflection of occult inflammation? Am J Gastroenterol 2010;105:1789-1884.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1789-1884
    • Keohane, J.1    O'Mahony, C.2    O'Mahony, L.3
  • 50
    • 33646154460 scopus 로고    scopus 로고
    • The Manitoba Inflammatory Bowel Disease Cohort Study: Prolonged symptoms before diagnosis: How much is irritable bowel syndrome?
    • Burgmann T, Clara I, Graff L, et al. The Manitoba Inflammatory Bowel Disease Cohort Study: prolonged symptoms before diagnosis: how much is irritable bowel syndrome? Clin Gastroenterol Hepatol 2006;4:614-620.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 614-620
    • Burgmann, T.1    Clara, I.2    Graff, L.3
  • 51
    • 57249089713 scopus 로고    scopus 로고
    • Rifaximin for the treatment of diarrhea-associated irritable bowel syndrome: Short-term treatment leading to long term sustained response
    • Lembo A, Zakko SF, Ferreira NL, et al. Rifaximin for the treatment of diarrhea-associated irritable bowel syndrome: short-term treatment leading to long term sustained response. Gastroenterology 2008;134:A-545.
    • (2008) Gastroenterology , vol.134
    • Lembo, A.1    Zakko, S.F.2    Ferreira, N.L.3
  • 52
    • 67649368679 scopus 로고    scopus 로고
    • Predictors of clinical response from a phase 2 multicenter efficacy trial using rifaximin, a gut-selective, nonabsorbed antibiotic for the treatment of diarrhea-associated irritable bowel syndrome
    • Ringel Y, Zakko SF, Ferreira NL, et al. Predictors of clinical response from a phase 2 multicenter efficacy trial using rifaximin, a gut-selective, nonabsorbed antibiotic for the treatment of diarrhea-associated irritable bowel syndrome. Gastroenterology 2008;134:A-550.
    • (2008) Gastroenterology , vol.134
    • Ringel, Y.1    Zakko, S.F.2    Ferreira, N.L.3
  • 53
    • 78650864077 scopus 로고    scopus 로고
    • Rifaximin therapy for patients with irritable bowel syndrome without constipation
    • Pimentel M, Lembo A, Chey WD, et al. Rifaximin therapy for patients with irritable bowel syndrome without constipation. New Engl J Med 2011;364:22-32.
    • (2011) New Engl J Med , vol.364 , pp. 22-32
    • Pimentel, M.1    Lembo, A.2    Chey, W.D.3
  • 54
    • 79951570315 scopus 로고    scopus 로고
    • Therapies aimed at the gut microbiota and inflammation: Antibiotics, prebiotics, probiotics, synbiotics, anti-inflammatory therapies
    • Quigley EM. Therapies aimed at the gut microbiota and inflammation: antibiotics, prebiotics, probiotics, synbiotics, anti-inflammatory therapies. Gastroenterol Clin North Am 2011;40:207-222.
    • (2011) Gastroenterol Clin North Am , vol.40 , pp. 207-222
    • Quigley, E.M.1
  • 55
    • 77649275204 scopus 로고    scopus 로고
    • Prebiotics and probiotics; modifying and mining the microbiota
    • Quigley EM. Prebiotics and probiotics; modifying and mining the microbiota. Pharmacol Res 2010;61:213-218.
    • (2010) Pharmacol Res , vol.61 , pp. 213-218
    • Quigley, E.M.1
  • 56
    • 77749318556 scopus 로고    scopus 로고
    • The efficacy of probiotics in the therapy of irritable bowel syndrome: A systematic review
    • Moayyedi P, Ford AC, Talley NJ, et al. The efficacy of probiotics in the therapy of irritable bowel syndrome: a systematic review. Gut 2010;59:325-332.
    • (2010) Gut , vol.59 , pp. 325-332
    • Moayyedi, P.1    Ford, A.C.2    Talley, N.J.3
  • 57
    • 65449172901 scopus 로고    scopus 로고
    • The utility of probiotics in the treatment of irritable bowel syndrome: A systematic review
    • Brenner DM, Moeller MJ, Chey WD, Schoenfeld PS. The utility of probiotics in the treatment of irritable bowel syndrome: a systematic review. Am J Gastroenterol 2009;104:1033-1049.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1033-1049
    • Brenner, D.M.1    Moeller, M.J.2    Chey, W.D.3    Schoenfeld, P.S.4
  • 58
    • 59149093199 scopus 로고    scopus 로고
    • Clinical trial: The effects of a transgalactooligosaccheride on faecal microbiota and symptoms in irritable bowel syndrome
    • Silk DBA, Davis A, Vulevic J, et al. Clinical trial: the effects of a transgalactooligosaccheride on faecal microbiota and symptoms in irritable bowel syndrome. Aliment Pharmacol Ther 2009;29:508-518.
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 508-518
    • Silk, D.B.A.1    Davis, A.2    Vulevic, J.3
  • 59
    • 79953781975 scopus 로고    scopus 로고
    • Antibiotic therapy in inflammatory bowel disease: A systematic review and meta-analysis
    • Khan KJ, Ullman TA, Ford AC, et al. Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis. Am J Gastroenterol 2011;106:661-673. A detailed, high-quality systematic review and meta-analysis which does reveal evidence of efficacy for antibiotics in the induction of remission in both Crohn's disease and ulcerative colitis; however, the use of abroad range of antibiotics makes it difficult to translate these findings into a clinical recommendation. More trials needed!
    • (2011) Am J Gastroenterol , vol.106 , pp. 661-673
    • Khan, K.J.1    Ullman, T.A.2    Ford, A.C.3
  • 60
    • 68049093112 scopus 로고    scopus 로고
    • Antibiotics and probiotics in inflammatory bowel disease: Why, when, and how
    • Prantera C, Scribano ML. Antibiotics and probiotics in inflammatory bowel disease: why, when, and how. Curr Opin Gastroenterol 2009;25:329-333.
    • (2009) Curr Opin Gastroenterol , vol.25 , pp. 329-333
    • Prantera, C.1    Scribano, M.L.2
  • 61
    • 77949770445 scopus 로고    scopus 로고
    • Interventions for prevention of postoperative recurrence of Crohn's disease
    • Doherty G, Bennett G, Patil S, et al. Interventions for prevention of postoperative recurrence of Crohn's disease. Cochrane Database Syst Rev 2009;CD006873.
    • (2009) Cochrane Database Syst Rev
    • Doherty, G.1    Bennett, G.2    Patil, S.3
  • 62
    • 75749113277 scopus 로고    scopus 로고
    • Long-term antibiotic treatment for Crohn's disease: Systematic review and meta-analysis of placebo-controlled trials
    • Feller M, Huwiler K, Schoepfer A, et al. Long-term antibiotic treatment for Crohn's disease: systematic review and meta-analysis of placebo-controlled trials. Clin Infect Dis 2010;50:473-480.
    • (2010) Clin Infect Dis , vol.50 , pp. 473-480
    • Feller, M.1    Huwiler, K.2    Schoepfer, A.3
  • 63
    • 77954960655 scopus 로고    scopus 로고
    • Treatment and prevention of pouchitis after ileal pouch-anal anatomises for chronic ulcerative colitis
    • Holubar SD, Cima RR, Sandborn WJ, Pardi DS. Treatment and prevention of pouchitis after ileal pouch-anal anatomises for chronic ulcerative colitis. Cochrane Database Syst Rev 2010;CD001176.
    • (2010) Cochrane Database Syst Rev
    • Holubar, S.D.1    Cima, R.R.2    Sandborn, W.J.3    Pardi, D.S.4
  • 64
    • 77957911673 scopus 로고    scopus 로고
    • Pharmabiotic manipulation of the microbiota in gastrointestinal disorders, from rationale to reality
    • Shanahan F, Collins SM. Pharmabiotic manipulation of the microbiota in gastrointestinal disorders, from rationale to reality. Gastroenterol Clin North Am 2010;39:721-726. A comprehensive and critical review of the current status of 'pharmabiotics' in the management of gastrointestinal disorders, including IBS and IBD.
    • (2010) Gastroenterol Clin North Am , vol.39 , pp. 721-726
    • Shanahan, F.1    Collins, S.M.2
  • 65
    • 33845910428 scopus 로고    scopus 로고
    • The role of antibiotic and probiotic therapies in current and future management of inflammatory bowel disease
    • DOI 10.1007/s11894-006-0039-z
    • Ewaschuk JB, Tejpar QZ, Soo I, et al. The role of antibiotic and probiotic therapies in current and future management of inflammatory bowel disease. Curr Gastroenterol Rep 2006;8:486-498. (Pubitemid 46017161)
    • (2006) Current Gastroenterology Reports , vol.8 , Issue.6 , pp. 486-498
    • Ewaschuk, J.B.1    Tejpar, Q.Z.2    Soo, I.3    Madsen, K.L.4    Fedorak, R.N.5
  • 66
    • 79958221480 scopus 로고    scopus 로고
    • Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease
    • Epub ahead of print
    • Benjamin JL, Hedin CR, Koutsoumpas A, et al. Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease. Gut 2011 [Epub ahead of print].
    • (2011) Gut
    • Benjamin, J.L.1    Hedin, C.R.2    Koutsoumpas, A.3


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