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Volumn 33, Issue 4, 2011, Pages 443-452

Methadone, cocaine, opiates, and metabolite disposition in umbilical cord and correlations to maternal methadone dose and neonatal outcomes

Author keywords

Cocaine; In utero drug exposure; Methadone; Opiates; Umbilical cord

Indexed keywords

2 ETHYLIDENE 1,5 DIMETHYL 3,3 DIPHENYLPYRROLIDINE; COCAINE; ILLICIT DRUG; METHADONE; OPIATE;

EID: 80051789107     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/FTD.0b013e31822724f0     Document Type: Article
Times cited : (45)

References (52)
  • 2
    • 0037077803 scopus 로고    scopus 로고
    • Drug abuse's smallest victims: In utero drug exposure
    • Huestis MA, Choo RE. Drug abuse's smallest victims: in utero drug exposure. Forensic Sci Int. 2002;128:20-30.
    • (2002) Forensic Sci Int , vol.128 , pp. 20-30
    • Huestis, M.A.1    Choo, R.E.2
  • 3
    • 84907133642 scopus 로고
    • The consequences of prenatal substance use for the developing fetus, newborn, and young child
    • Behnke M, Eyler FD. The consequences of prenatal substance use for the developing fetus, newborn, and young child. Int J Addict. 1993;28: 1341-1391. (Pubitemid 23350948)
    • (1993) International Journal of the Addictions , vol.28 , Issue.13 , pp. 1341-1391
    • Behnke, M.1    Eyler, F.D.2
  • 5
    • 0030250836 scopus 로고    scopus 로고
    • The effects of prenatal cocaine use on neonatal neurobehavioral status
    • DOI 10.1016/0892-0362(96)00062-1
    • Richardson GA, Hamel SC, Goldschmidt L, et al. The effects of prenatal cocaine use on neonatal neurobehavioral status. Neurotoxicol Teratol. 1996;18:519-528. (Pubitemid 26346097)
    • (1996) Neurotoxicology and Teratology , vol.18 , Issue.5 , pp. 519-528
    • Richardson, G.A.1    Hamel, S.C.2    Goldschmidt, L.3    Day, N.L.4
  • 7
    • 73449121924 scopus 로고    scopus 로고
    • Prenatal methadone exposure and neonatal neurobehavioral functioning
    • Velez ML, Jansson LM, Schroeder J, et al. Prenatal methadone exposure and neonatal neurobehavioral functioning. Pediatr Res. 2009;66:704-709.
    • (2009) Pediatr Res , vol.66 , pp. 704-709
    • Velez, M.L.1    Jansson, L.M.2    Schroeder, J.3
  • 8
    • 51149115082 scopus 로고    scopus 로고
    • Methadone maintenance vs. methadone taper during pregnancy: Maternal and neonatal outcomes
    • Jones HE, O'Grady KE, Malfi D, et al. Methadone maintenance vs. methadone taper during pregnancy: maternal and neonatal outcomes. Am J Addict. 2008;17:372-386.
    • (2008) Am J Addict , vol.17 , pp. 372-386
    • Jones, H.E.1    O'grady, K.E.2    Malfi, D.3
  • 9
    • 0026076829 scopus 로고
    • Treatment issues for opioid-dependent women during the perinatal period
    • Finnegan LP. Treatment issues for opioid-dependent women during the perinatal period. J Psychoactive Drugs. 1991;23:191-201.
    • (1991) J Psychoactive Drugs , vol.23 , pp. 191-201
    • Finnegan, L.P.1
  • 10
    • 49249097100 scopus 로고    scopus 로고
    • Treating pregnant women dependent on opioids is not the same as treating pregnancy and opioid dependence: A knowledge synthesis for better treatment for women and neonates
    • Winklbaur B, Kopf N, Ebner N, et al. Treating pregnant women dependent on opioids is not the same as treating pregnancy and opioid dependence: a knowledge synthesis for better treatment for women and neonates. Addiction. 2008;103:1429-1440.
    • (2008) Addiction , vol.103 , pp. 1429-1440
    • Winklbaur, B.1    Kopf, N.2    Ebner, N.3
  • 11
    • 63049126145 scopus 로고    scopus 로고
    • Opioid maintenance treatment during pregnancy: Occurrence and severity of neonatal abstinence syndrome. A national prospective study
    • Bakstad B, Sarfi M,Welle-Strand GK, et al. Opioid maintenance treatment during pregnancy: occurrence and severity of neonatal abstinence syndrome. A national prospective study. Eur Addict Res. 2009;15: 128-134.
    • (2009) Eur Addict Res , vol.15 , pp. 128-134
    • Bakstad, B.1    Sarfi, M.2    Welle-Strand, G.K.3
  • 13
    • 62149133757 scopus 로고    scopus 로고
    • Maternal methadone use in pregnancy: Factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources
    • Dryden C, Young D, Hepburn M, et al. Maternal methadone use in pregnancy: factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources. BJOG. 2009;116:665-671.
    • (2009) BJOG , vol.116 , pp. 665-671
    • Dryden, C.1    Young, D.2    Hepburn, M.3
  • 16
    • 0347383736 scopus 로고    scopus 로고
    • Stereoselective Metabolism of Methadone N-Demethylation by Cytochrome P4502B6 and 2C19
    • DOI 10.1002/chir.10303
    • Gerber JG, Rhodes RJ, Gal J. Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19. Chirality. 2004;16: 36-44. (Pubitemid 37532283)
    • (2004) Chirality , vol.16 , Issue.1 , pp. 36-44
    • Gerber, J.G.1    Rhodes, R.J.2    Gal, J.3
  • 18
    • 0037184794 scopus 로고    scopus 로고
    • Polymorphism of cytochrome P450 and xenobiotic toxicity
    • DOI 10.1016/S0300-483X(02)00492-4, PII S0300483X02004924
    • Ingelman-Sundberg M. Polymorphism of cytochrome P450 and xenobiotic toxicity. Toxicology. 2002;181-182:447-452. (Pubitemid 36015735)
    • (2002) Toxicology , vol.181-182 , pp. 447-452
    • Ingelman-Sundberg, M.1
  • 19
    • 33748187632 scopus 로고    scopus 로고
    • Toxicokinetics of drugs of abuse: Current knowledge of the isoenzymes involved in the human metabolism of tetrahydrocannabinol, cocaine, heroin, morphine, and codeine
    • DOI 10.1097/01.ftd.0000211812.27558.6e, PII 0000769120060600000027
    • Maurer HH, Sauer C, Theobald DS. Toxicokinetics of drugs of abuse: current knowledge of the isoenzymes involved in the human metabolism of tetrahydrocannabinol, cocaine, heroin, morphine, and codeine. Ther Drug Monit. 2006;28:447-453. (Pubitemid 44314935)
    • (2006) Therapeutic Drug Monitoring , vol.28 , Issue.3 , pp. 447-453
    • Maurer, H.H.1    Sauer, C.2    Theobald, D.S.3
  • 22
    • 0036898460 scopus 로고    scopus 로고
    • Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability
    • DOI 10.1093/bja/aef284
    • Williams DG, Patel A, Howard RF. Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability. Br J Anaesth. 2002;89:839-845. (Pubitemid 35460521)
    • (2002) British Journal of Anaesthesia , vol.89 , Issue.6 , pp. 839-845
    • Williams, D.G.1    Patel, A.2    Howard, R.F.3
  • 23
    • 70349659641 scopus 로고    scopus 로고
    • Fatal and severe codeine intoxication in 3-year-old twins-interpretation of drug and metabolite concentrations
    • Ferreiros N, Dresen S, Hermanns-Clausen M, et al. Fatal and severe codeine intoxication in 3-year-old twins-interpretation of drug and metabolite concentrations. Int J Legal Med. 2009;123:387-394.
    • (2009) Int J Legal Med , vol.123 , pp. 387-394
    • Ferreiros, N.1    Dresen, S.2    Hermanns-Clausen, M.3
  • 25
    • 1642523162 scopus 로고    scopus 로고
    • Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
    • DOI 10.1016/j.clpt.2003.09.012
    • Marzolini C, Paus E, Buclin T, et al. Polymorphisms in human MDR1 (Pglycoprotein): recent advances and clinical relevance. Clin Pharmacol Ther. 2004;75:13-33. (Pubitemid 38130115)
    • (2004) Clinical Pharmacology and Therapeutics , vol.75 , Issue.1 , pp. 13-33
    • Marzolini, C.1    Paus, E.2    Buclin, T.3    Kim, R.B.4
  • 26
    • 54249118552 scopus 로고    scopus 로고
    • Correlations of maternal buprenorphine dose, buprenorphine, and metabolite concentrations in meconium with neonatal outcomes
    • Kacinko SL, Jones HE, Johnson RE, et al. Correlations of maternal buprenorphine dose, buprenorphine, and metabolite concentrations in meconium with neonatal outcomes. Clin Pharmacol Ther. 2008;84: 604-612.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 604-612
    • Kacinko, S.L.1    Jones, H.E.2    Johnson, R.E.3
  • 27
    • 77956376715 scopus 로고    scopus 로고
    • Identifying prenatal cannabis exposure and effects of concurrent tobacco exposure on neonatal growth
    • Gray TR, Eiden RD, Leonard KE, et al. Identifying prenatal cannabis exposure and effects of concurrent tobacco exposure on neonatal growth. Clin Chem. 2010;56:1442-1450.
    • (2010) Clin Chem , vol.56 , pp. 1442-1450
    • Gray, T.R.1    Eiden, R.D.2    Leonard, K.E.3
  • 30
    • 0002126897 scopus 로고
    • Neonatal abstinence syndrome
    • Hoekelman RA Friedman SB Nelson NM et al eds. St Louis MO: Mosby -Year Book
    • Finnegan LP, Kaltenbach K. Neonatal abstinence syndrome. In: Hoekelman RA, Friedman SB, Nelson NM, et al, eds. Primary Pediatric Care. St Louis, MO: Mosby-Year Book; 1992:1367-1378.
    • (1992) Primary Pediatric Care , pp. 1367-1378
    • Finnegan, L.P.1    Kaltenbach, K.2
  • 31
    • 69749122064 scopus 로고    scopus 로고
    • Development and validation of a liquid chromatography mass spectrometry assay for the simultaneous quantification of methadone, cocaine, opiates and metabolites in human umbilical cord
    • de Castro A, Concheiro M, Shakleya DM, et al. Development and validation of a liquid chromatography mass spectrometry assay for the simultaneous quantification of methadone, cocaine, opiates and metabolites in human umbilical cord. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877:3065-3071.
    • (2009) J Chromatogr B Analyt Technol Biomed Life Sci , vol.877 , pp. 3065-3071
    • De Castro, A.1    Concheiro, M.2    Shakleya, D.M.3
  • 32
    • 68949099204 scopus 로고    scopus 로고
    • Simultaneous quantification of methadone, cocaine, opiates, and metabolites in human placenta by liquid chromatography-mass spectrometry
    • de Castro A, Concheiro M, Shakleya DM, et al. Simultaneous quantification of methadone, cocaine, opiates, and metabolites in human placenta by liquid chromatography-mass spectrometry. J Anal Toxicol. 2009;33:243-252.
    • (2009) J Anal Toxicol , vol.33 , pp. 243-252
    • De Castro, A.1    Concheiro, M.2    Shakleya, D.M.3
  • 33
    • 11844250580 scopus 로고    scopus 로고
    • Determination of methadone, 2-ethylidene-1,5-dimethyl-3,3- diphenylpyrrolidine, 2-ethyl-5-methyl-3,3-diphenylpyraline and methadol in meconium by liquid chromatography atmospheric pressure chemical ionization tandem mass spectrometry
    • DOI 10.1016/j.jchromb.2004.10.068, PII S1570023204008979
    • Choo RE, Murphy CM, Jones HE, et al. Determination of methadone, 2-ethylidene-1, 5-dimethyl-3, 3-diphenylpyrrolidine, 2-ethyl-5-methyl-3, 3-diphenylpyraline and methadol in meconium by liquid chromatography atmospheric pressure chemical ionization tandem mass spectrometry. J Chromatogr B, Analyt Technol Biomed Life Sci. 2005;814:369-373. (Pubitemid 40091657)
    • (2005) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.814 , Issue.2 , pp. 369-373
    • Choo, R.E.1    Murphy, C.M.2    Jones, H.E.3    Huestis, M.A.4
  • 34
    • 63449101736 scopus 로고    scopus 로고
    • A liquid chromatography tandem mass spectrometry method for the simultaneous quantification of 20 drugs of abuse and metabolites in human meconium
    • Gray TR, Shakleya DM, Huestis MA. A liquid chromatography tandem mass spectrometry method for the simultaneous quantification of 20 drugs of abuse and metabolites in human meconium. Anal Bioanal Chem. 2009; 393:1977-1990.
    • (2009) Anal Bioanal Chem , vol.393 , pp. 1977-1990
    • Gray, T.R.1    Shakleya, D.M.2    Huestis, M.A.3
  • 35
    • 3343017655 scopus 로고    scopus 로고
    • Neonatal abstinence syndrome in methadone-exposed infants is altered by level of prenatal tobacco exposure
    • DOI 10.1016/j.drugalcdep.2004.03.012, PII S0376871604000924
    • Choo RE, Huestis MA, Schroeder JR, et al. Neonatal abstinence syndrome in methadone-exposed infants is altered by level of prenatal tobacco exposure. Drug Alcohol Depend. 2004;75:253-260. (Pubitemid 38993295)
    • (2004) Drug and Alcohol Dependence , vol.75 , Issue.3 , pp. 253-260
    • Choo, R.E.1    Huestis, M.A.2    Schroeder, J.R.3    Shin, A.S.4    Jones, H.E.5
  • 36
    • 0027336245 scopus 로고
    • Relationships between maternal methadone dosage, maternal-neonatal methadone levels, and neonatal withdrawal
    • Doberczak TM, Kandall SR, Friedmann P. Relationships between maternal methadone dosage, maternal-neonatal methadone levels, and neonatal withdrawal. Obstet Gynecol. 1993;81:936.
    • (1993) Obstet Gynecol , vol.81 , pp. 936
    • Doberczak, T.M.1    Kandall, S.R.2    Friedmann, P.3
  • 39
    • 0034704455 scopus 로고    scopus 로고
    • Plasma concentrations of the enantiomers of methadone and therapeutic response in methadone maintenance treatment
    • Eap CB, Bourquin M, Martin JL, et al. Plasma concentrations of the enantiomers of methadone and therapeutic response in methadone maintenance treatment. Drug Alcohol Depend. 2000;61:47-54.
    • (2000) Drug Alcohol Depend , vol.61 , pp. 47-54
    • Eap, C.B.1    Bourquin, M.2    Martin, J.L.3
  • 40
    • 0017761752 scopus 로고
    • Maternal ingested methadone, body fluid methadone, and the neonatal withdrawal syndrome
    • Harper RG, Solish G, Feingold E, et al. Maternal ingested methadone, body fluid methadone, and the neonatal withdrawal syndrome. Am J Obstet Gynecol. 1977;129:417-424. (Pubitemid 8211784)
    • (1977) American Journal of Obstetrics and Gynecology , vol.129 , Issue.4 , pp. 417-424
    • Harper, R.G.1    Solish, G.2    Feingold, E.3
  • 41
    • 0017661797 scopus 로고
    • The narcotic-dependent mother: Fetal and neonatal consequences
    • Kandall SR, Albin S, Gartner LM, et al. The narcotic-dependent mother: fetal and neonatal consequences. Early Hum Dev. 1977;1:159-169. (Pubitemid 8224194)
    • (1977) Early Human Development , vol.1 , Issue.2 , pp. 159-169
    • Kandall, S.R.1    Albin, S.2    Gartner, L.M.3
  • 42
    • 0018065667 scopus 로고
    • Management of pregnant drug-dependent women
    • Finnegan LP. Management of pregnant drug-dependent women. Ann N Y Acad Sci. 1978;311:135-146.
    • (1978) Ann N y Acad Sci , vol.311 , pp. 135-146
    • Finnegan, L.P.1
  • 43
    • 0025739561 scopus 로고
    • Perinatal substance abuse: Comments and perspectives
    • Finnegan LP. Perinatal substance abuse: comments and perspectives. Semin Perinatol. 1991;15:331-339.
    • (1991) Semin Perinatol , vol.15 , pp. 331-339
    • Finnegan, L.P.1
  • 44
    • 0016417245 scopus 로고
    • Disposition of methadone and its relationship to severity of withdrawal in the newborn
    • Rosen TS, Pippenger CE. Disposition of methadone and its relationship to severity of withdrawal in the newborn. Addict Dis. 1975;2:169-178.
    • (1975) Addict Dis , vol.2 , pp. 169-178
    • Rosen, T.S.1    Pippenger, C.E.2
  • 45
    • 0017186482 scopus 로고
    • Pharmacologic observations on the neonatal withdrawal syndrome
    • Rosen TS, Pippenger CE. Pharmacologic observations on the neonatal withdrawal syndrome. J Pediatr. 1976;88:1044-1048.
    • (1976) J Pediatr , vol.88 , pp. 1044-1048
    • Rosen, T.S.1    Pippenger, C.E.2
  • 47
  • 48
    • 43549115662 scopus 로고    scopus 로고
    • Validated method for the simultaneous determination of methadone and its main metabolites (EDDP and EMDP) in plasma of umbilical cord blood by gas chromatography-mass spectrometry
    • Nikolaou PD, Papoutsis II, Atta-Politou J, et al. Validated method for the simultaneous determination of methadone and its main metabolites (EDDP and EMDP) in plasma of umbilical cord blood by gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2008;867:219-225.
    • (2008) J Chromatogr B Analyt Technol Biomed Life Sci , vol.867 , pp. 219-225
    • Nikolaou, P.D.1    Papoutsis, I.I.2    Atta-Politou, J.3
  • 49
    • 0027510079 scopus 로고
    • Determination of cocaine and its major metabolite, benzoylecgonine, in amniotic fluid, umbilical cord blood, umbilical cord tissue, and neonatal urine: A case study [1]
    • Moore CM, Brown S, Negrusz A, et al. Determination of cocaine and its major metabolite, benzoylecgonine, in amniotic fluid, umbilical cord blood, umbilical cord tissue, and neonatal urine: a case study. J Anal Toxicol. 1993; 17:62. (Pubitemid 23030894)
    • (1993) Journal of Analytical Toxicology , vol.17 , Issue.1 , pp. 62
    • Moore, C.M.1    Brown, S.2    Negrusz, A.3    Tebbett, I.4    Meyer, W.5    Jain, L.6
  • 51
    • 55749093088 scopus 로고    scopus 로고
    • Using umbilical cord tissue to detect fetal exposure to illicit drugs: A multicentered study in Utah and New Jersey
    • Montgomery DP, Plate CA, Jones M, et al. Using umbilical cord tissue to detect fetal exposure to illicit drugs: a multicentered study in Utah and New Jersey. J Perinatol. 2008;28:750-753.
    • (2008) J Perinatol , vol.28 , pp. 750-753
    • Montgomery, D.P.1    Plate, C.A.2    Jones, M.3
  • 52
    • 78751645527 scopus 로고    scopus 로고
    • Nicotine and metabolites in paired umbilical cord tissue and meconium specimens
    • Marin SJ, Christensen RD, Baer VL, et al. Nicotine and metabolites in paired umbilical cord tissue and meconium specimens. Ther Drug Monit. 2010;33:80-85.
    • (2010) Ther Drug Monit , vol.33 , pp. 80-85
    • Marin, S.J.1    Christensen, R.D.2    Baer, V.L.3


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